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Efficacy of Photobiomodulation Therapy Utilizing 808 nm and 660 nm Alone and in Combination for Treatment of Paresthesia in Rats
Published 2024-12-01“…<b>Methods</b>: This animal study was conducted on 36 adult male Wistar rats. …”
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62
Application of stem cells alone and in combination with low-level laser therapy for sciatic nerve repair in rats
Published 2025-01-01“…Abstract This study evaluated the efficacy of tubular constructs containing stem cells and Type I collagen, both independently and in conjunction with low-level laser therapy (LLLT), in repairing the sciatic nerve in a rat model. In this animal study, the right sciatic nerve of 30 male Wistar rats, each weighing 250–300 g, was surgically excised to a length of 8 mm. …”
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63
Separate Evaluation of the Effects of Hydroalcoholic Extracts of Eryngium Caucasicum L. and Zataria Multiflora L. on Gastric Ulcers in an Animal Model
Published 2024-12-01“…Cultivated Artemia salina was used to evaluate the toxicity of the extracts. The animal study was conducted using eight groups of Balb/c mice. …”
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64
Anticancer effect of the antirheumatic drug leflunomide on oral squamous cell carcinoma by the inhibition of tumor angiogenesis
Published 2025-01-01“…LEF dose-dependently suppressed endothelial tube formation. In the animal study, LEF significantly suppressed tumor growth in both immunodeficient and syngeneic mice. …”
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65
Deep-learning based electromagnetic navigation system for transthoracic percutaneous puncture of small pulmonary nodules
Published 2025-01-01“…In the phantom study, the DL-EMNS group showed a higher technical success rate (95.6% vs. 77.8%, p = 0.027), smaller error (1.47 ± 1.62 mm vs. 3.98 ± 2.58 mm, p < 0.001), shorter procedure duration (291.56 ± 150.30 vs. 676.44 ± 246.12 s, p < 0.001), and fewer number of CT acquisitions (1.2 ± 0.66 vs. 2.93 ± 0.98, p < 0.001) compared to the traditional CT-guided group. In the animal study, DL-EMNS significantly improved technical success rate (100% vs. 84.0%, p = 0.015), reduced operation time (121.36 ± 38.87 s vs. 321.60 ± 129.12 s, p < 0.001), number of CT acquisitions (1.09 ± 0.29 vs. 2.96 ± 0.73, p < 0.001) and complication rate (0% vs. 20%, p = 0.002). …”
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66
Basic research for ultrasound-guided injection into skeletal muscle lesions in an experimental animal model
Published 2025-01-01“…Conclusion: This experimental animal study demonstrated the potential of ultrasound to quantitatively visualize abnormalities of skeletal muscle. …”
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67
Effects of biophilic virtual reality on cognitive function of patients undergoing laparoscopic surgery: study protocol for a sham randomised controlled trial
Published 2022-07-01“…Due to the lack of an effective postoperative follow-up system, the incidence of POCD in China is not clear, and although many drugs have been proposed to improve POCD in the animal study, their clinical applications are limited, while VR provides an innovative method to provide non-pharmacological management.Methods and design This is a single-centre, randomised, double-blind, sham-controlled clinical trial. …”
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68
The Inhibitory Effect of Connective Tissue Growth Factor Antibody on Postoperative Fibrosis in a Rabbit Model of Trabeculectomy
Published 2022-11-01“…Conclusion: Based on the results of this animal study, the anti-CTGF antibody injection resulted in a significant reduction in collagenous tissue and myofibroblast cells after trabeculectomy.…”
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Effects of Diet on Brain Plasticity in Animal and Human Studies: Mind the Gap
Published 2014-01-01“…Lastly, we discuss some of the obstacles to harnessing the promising effects of diet on brain plasticity in animal studies into effective recommendations and interventions to promote healthy brain function in humans. …”
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71
Efficacy and Safety Concerns with Sn-Mesoporphyrin as an Adjunct Therapy in Neonatal Hyperbilirubinemia: A Literature Review
Published 2022-01-01“…This review evaluates in-vitro studies, animal studies, and clinical trials for the efficacy and safety of tin analogues of metalloporphyrin. …”
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72
Cyclosporine and Herbal Supplement Interactions
Published 2014-01-01“…Decreased CyA blood concentration has been shown with St John’s wort in case reports and, in vivo animal studies, with ginger, liquorice, scutellariae radix, and quercetin. …”
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73
Nutritional Supplementation with the Mushroom Agaricus sylvaticus Reduces Oxidative Stress in Children with HIV
Published 2014-01-01“…BACKGROUND: The involvement of free radicals and oxidative stress in HIV infection has been extensively studied, and the benefits of antioxidant supplementation in animal studies have been demonstrated. However, few studies have demonstrated a benefit in clinical studies.…”
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74
The Role of Gut Microbiota Modification in Nonalcoholic Fatty Liver Disease Treatment Strategies
Published 2024-01-01“…However, further investigations are required to generalize the outcomes of animal studies to humans.…”
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75
Transdermal delivery of tolterodine tartrate for overactive bladder treatment: In vitro and in vivo evaluation
Published 2017-09-01“…There were no significant interactions between TT and other excipients. Animal studies indicated that the TT patch reduced the incidence of side effects; however, studies of longer duration are required to determine the effectiveness in treating OAB.…”
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76
(Mesenchymal) Stem Cell-Based Therapy in Cisplatin-Induced Acute Kidney Injury Animal Model: Risk of Immunogenicity and Tumorigenicity
Published 2017-01-01“…Although MSCs have potent immunosuppressive properties, animal studies also suggest that transplanted MSCs may elicit immune response. …”
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77
Sympathoexcitation Associated with Renin-Angiotensin System in Metabolic Syndrome
Published 2013-01-01“…As a novel aspect connecting the importance of SNS and RAS activation, we and other investigators have recently demonstrated that angiotensin II type 1 receptor (AT1R) blockers (ARBs) improve SNS activation in patients with MetS. In the animal studies, SNS activation is regulated by the AT1R-induced oxidative stress in the brain. …”
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Examining the therapeutic potential and side effects of calcium channel blockers in mortality and morbidity of patients with stroke: A systematic review of pre-clinical and clinica...
Published 2025-06-01“…After the title and abstract screening, 56 human and animal studies were selected to be discussed in this article. …”
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Rethinking love, independence, and speciesism in assistance dog discourse
Published 2025-01-01“…Incorporating insights from human-animal studies and disability studies, the paper seeks to enrich sociological research on emotions and power structures, advocating for a shift toward valuing the labor and wellbeing of assistance dogs. …”
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Bovine Antibody-Based Oral Immunotherapy for Reduction of Intragastric Helicobacter pylori Colonization: A Randomized Clinical Trial
Published 2011-01-01“…Effective prevention and eradication of H pylori by passive immunization with orally administered bovine antibodies has been demonstrated in animal studies, and may serve as an alternative therapy in humans.…”
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