Fetal Growth Restriction Prediction: How to Move beyond by Debora F. B. Leite, Jose G. Cecatti

“…Placental growth factor levels are decreased in SGA pregnancies, and it is the most promising biomarker in differentiating angiogenesis-related SGA from other causes. Unfortunately, however, only few societies recommend universal screening. …”
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Gene Expression Profile Analysis in Epilepsy by Using the Partial Least Squares Method by Dong Wang, Xixiao Song, Yan Wang, Xia Li, Shanshan Jia, Zhijing Wang

“…For GO enrichment analysis, except for processes related to the nervous system, we also identified overrepresentation of dysregulated genes in angiogenesis. Network analysis revealed two hub genes, CUL3 and EP300, which may serve as potential targets in further therapeutic studies. …”
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Peroxisome Proliferator-Activated Receptor γ Regulates the Expression of Lipid Phosphate Phosphohydrolase 1 in Human Vascular Endothelial Cells by Yazi Huang, Beilei Zhao, Yahan Liu, Nanping Wang

“…Lipid phosphate phosphohydrolase 1 (LPP1), a membrane ectophosphohydrolase regulating the availability of bioactive lipid phosphates, plays important roles in cellular signaling and physiological processes such as angiogenesis and endothelial migration. However, the regulated expression of LPP1 remains largely unknown. …”
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Anticancer Role of PPARγ Agonists in Hematological Malignancies Found in the Vasculature, Marrow, and Eyes by P. J. Simpson-Haidaris, S. J. Pollock, S. Ramon, N. Guo, C. F. Woeller, S. E. Feldon, R. P. Phipps

“…This paper has two objectives: first to highlight the potential uses for PPARγ agonists in anticancer therapy with special emphasis on their role when used as adjuvant or combined therapy in the treatment of hematological malignancies found in the vasculature, marrow, and eyes, and second, to review the potential role PPARγ and/or its ligands may have in modulating cancer-associated angiogenesis and tumor-stromal microenvironment crosstalk in bone marrow.…”
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The Effect and Related Mechanism of Action of Astragalus Compatible with Curcumin against Colon Cancer Metastasis in Mice by Jiafei Wu, Decai Tang

“…During tumor metastasis, cancer cells first enhance their proliferative capacity by lowering autophagy and apoptosis, and then, their capacity is stimulated by boosting tumors’ ability to take nutrients from the outside via angiogenesis. Traditional treatment focuses on eliminating tumor cells by triggering cell death or activating the immune system, which often results in side effects or chemoresistance recurrence. …”
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Improvement of the Survival of Human Autologous Fat Transplantation by Adipose-Derived Stem-Cells-Assisted Lipotransfer Combined with bFGF by Aimei Jiang, Ming Li, Wenjing Duan, Yilong Dong, Yanmei Wang

“…This study was designed to test the hypothesis that basic fibroblast growth factor (bFGF) may improve the effects of ASCs because it owns the property to boost angiogenesis. In the present study, human fat tissues were mixed with ASCs, ASCs plus 100 U bFGF, or medium as the control and then injected subcutaneously into immunologically compromised nude mice for 12 weeks. …”
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The Antiangiogenic Effects of a Vascular Endothelial Growth Factor Decoy Receptor Can Be Monitored in Vivo Using Contrast-Enhanced Ultrasound Imaging by Flemming Forsberg, Raymond J. Ro, Andrew Marshall, Ji-Bin Liu, See-Ying Chiou, Daniel A. Merton, Priscilla Machado, Adam P. Dicker, Levon N. Nazarian

“…Measures of tumor vascularity obtained with the different imaging modes were compared to immunohistochemical markers of angiogenesis. Mean tumor volume was smaller in the active group than in the control group (656 ± 225 vs 1,160 ± 605 mm 3 ). …”
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Integrated in silico and in vitro exploration of the anti-VEGFR-2 activities of a semisynthetic xanthine alkaloid inhibiting breast cancer. by Eslam B Elkaeed, Hazem Elkady, Ahmed M Khattab, Reda G Yousef, Hanan A Al-Ghulikah, Dalal Z Husein, Ibrahim M Ibrahim, Mohamed A Elkady, Ahmed M Metwaly, Ibrahim H Eissa

“…This study presents T-1-NBAB, a new compound derived from the natural xanthine alkaloid theobromine, aimed at inhibiting VEGFR-2, a crucial protein in angiogenesis. T-1-NBAB's potential to interacts with and inhibit the VEGFR-2 was indicated using in silico techniques like molecular docking, MD simulations, MM-GBSA, PLIP, essential dynamics, and bi-dimensional projection experiments. …”
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Targeting HIF-1α to Prevent Renal Ischemia-Reperfusion Injury: Does It Work? by Kapil Sethi, Kenny Rao, Damien Bolton, Oneel Patel, Joseph Ischia

“…HIF mediates metabolic adaptation, angiogenesis, erythropoiesis, cell growth, survival, and apoptosis. …”
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3D Segmentation and Visualization of Skin Vasculature Using Line-Field Confocal Optical Coherence Tomography by Oliver Mayer, Hanna Wirsching, Sophia Schlingmann, Julia Welzel, Sandra Schuh

“…The research aims to improve the understanding of tumor angiogenesis and the complex vascular morphology associated with malignancies. …”
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Vitreous Mediators in Retinal Hypoxic Diseases by Roberto dell'Omo, Francesco Semeraro, Giulio Bamonte, Francesco Cifariello, Mario R. Romano, Ciro Costagliola

“…Cytokines, which usually serve as signals between neighboring cells, are involved in essentially every important biological process, including cell proliferation, inflammation, immunity, migration, fibrosis, tissue repair, and angiogenesis. Cytokines and chemokines are multifunctional mediators that can direct the recruitment of leukocytes to sites of inflammation, promote the process, enhance immune responses, and promote stem cell survival, development, and homeostasis. …”
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Modulation of Immunity by Antiangiogenic Molecules in Cancer by Magali Terme, Orianne Colussi, Elie Marcheteau, Corinne Tanchot, Eric Tartour, Julien Taieb

“…In the last decades a new class of therapeutic drugs have been developed that block tumor angiogenesis. These antiangiogenic molecules, which target VEGF or VEGFR, PDGFR, and c-kit, can act not only on endothelial cells but also on immune cells. …”
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Exercise Training Effects on Inflammatory Gene Expression in White Adipose Tissue of Young Mice by Tracy Baynard, Victoria J. Vieira-Potter, Rudy J. Valentine, Jeffrey A. Woods

“…VEGF (indicator of angiogenesis) was greatest in the HF/EX versus the other 3 groups (). …”
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Comparative analysis of bone healing in subcritical defects with air turbine and electric handpiece in a rat model. by Izabella Sol, Henrique Hadad, Tatsuya Henrique Kano, Karen Rawen Tonini, Martina Andreia Lage Nunes, Daniela Ponzoni

“…A reduced number of inflammatory cells and increased angiogenesis in the initial periods was seen in EG, corroborating the consistent values of collagen type 1 and a decrease of collagen type 3 over times. …”
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Pinitol Improves Diabetic Foot Ulcers in Streptozotocin-Induced Diabetes Rats Through Upregulation of Nrf2/HO-1 Signaling by Jinsick Kim, Min Young Go, Chae Young Jeon, Jung Un Shin, Mujun Kim, Hye Won Lim, Dong Wook Shin

“…Furthermore, pinitol facilitated angiogenesis, contributing to improved wound healing. …”
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Plant-Derived Anti-Cancer Therapeutics and Biopharmaceuticals by Ghyda Murad Hashim, Mehdi Shahgolzari, Kathleen Hefferon, Afagh Yavari, Srividhya Venkataraman

“…A multifactorial and multitargeted approach is required towards intervention of the multitude of signaling pathways associated with carcinogenesis inclusive of angiogenesis and metastasis. In this context, plants provide an immense source of phytotherapeutics that show great promise as anticancer drugs. …”
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Therapeutic potential of mesenchymal stem cells and stem cell-derived extracellular vesicles in tuberculosis of various localizations: A review by Veronika V. Shumko, Andrei I. Gorelov, Anna N. Remezova, Yanina G. Ivanova, Alexandr N. Muraviov, Natalia M. Yudintceva, Tatiana I. Vinogradova, Anna A. Gorelova

“…The action of MSCs is mediated by the release of EV which play a direct role in the implementation of several important biological processes: angiogenesis, proliferation, modulation of the inflammatory process and immune response, inhibition of cellular apoptosis, etc. …”
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Tumor-Associated Mast Cells in Thyroid Cancer by Carla Visciano, Nella Prevete, Federica Liotti, Gianni Marone

“…Among the different cell populations that infiltrate cancer stroma, mast cells (MCs) can influence several aspects of tumor biology, including tumor development and progression, angiogenesis, lymphangiogenesis, and tissue remodelling. …”
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Cerenkov Luminescence Tomography of Aminopeptidase N (APN/CD13) Expression in Mice Bearing HT1080 Tumors by Zhenhua Hu, Weidong Yang, Xiaowei Ma, Wenhui Ma, Xiaochao Qu, Jimin Liang, Jing Wang, Jie Tian

“…The promising CLT technique could be potentially used for sensitively evaluating tumor angiogenesis in vivo.…”
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Molecular Circuits of Resolution in the Eye by Elvira L. Liclican, Karsten Gronert

“…Protective endogenous roles of LXA4 and NPD1 have been established utilizing lipidomic analysis, knockout mice, and pharmacological, genetic, and dietary manipulation, providing compelling evidence that these intrinsic lipid autacoid circuits play essential roles in restraining inflammation, promoting wound healing, inhibiting pathological angiogenesis, and providing neuroprotection in the delicate visual axis.…”
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