Increasing the meaningful involvement of women in HIV cure-related research: a qualitative interview study in the United States by Karine Dubé, Elizabeth Barr, Morgan Philbin, Amaya Perez-Brumer, Brian Minalga, Beth Peterson, Dawn Averitt, Bridgette Picou, Krista Martel, Cecilia Chung, María Mejía, Martha Cameron, Gail Graham, Lynda Dee, Dázon Dixon Diallo, Ebony Gordon, Anastasia Korolkova, Typhanye Dyer, Judith D. Auerbach, Eileen Scully, Krista L. Dong, Sara Gianella

“…Participants noted that women would be willing to participate in HIV cure trials, related procedures (e.g. biopsies), and analytical treatment interruptions. They also expressed a desired for women-centered and holistic clinical trial designs that account for intersectionality. …”
Get full text

Integrated hepatic transcriptomics and metabolomics identify Pck1 as a key factor in the broad dysregulation induced by vehicle pollutants by Gajalakshmi Ramanathan, Yuqi Zhao, Rajat Gupta, Siri Langmo, May Bhetraratana, Fen Yin, Will Driscoll, Jerry Ricks, Allen Louie, James A. Stewart, Timothy R. Gould, Timothy V. Larson, Joel Kaufman, Michael E. Rosenfeld, Xia Yang, Jesus A. Araujo

“…An integrated transcriptomic and metabolomic analytical strategy was employed to dissect critical pathways and identify candidate genes that could dissect DE-induced pathogenesis. …”
Get full text

Application of fourier transform infrared vibrational spectroscopy in identifying early biochemical changes in lipid profiles of individuals undergoing Roux-en-y gastric bypass by Amanda Motta de Bortoli, Márcia Helena Cassago Nascimento, Blanca Elena Guerrero Daboin, Beatriz Bobbio de Brito, Luiza Recla Pessotti, Paulo Roberto Filgueiras, Andressa Bolsoni Lopes, Valerio Garrone Barauna, Fabiano Kenji Haraguchi

“…Abstract Background Fourier transform infrared spectroscopy (FTIR) is an analytical technique increasingly applied in biological analysis. …”
Get full text

Tuberculosis and HIV/AIDS-attributed mortalities and associated sociodemographic factors in Papua New Guinea: evidence from the comprehensive health and epidemiological surveillanc... by Chalapati Rao, Willie Pomat, Tony Okely, Bang Nguyen Pham, Norah Abori, Vinson D Silas, Ronny Jorry

“…This study examines TB and HIV/AIDS mortalities and associated sociodemographic factors in PNG.Method As part of a longitudinal study, verbal autopsy (VA) interviews were conducted using the WHO 2016 VA Instrument to collect data of 926 deaths occurred in the communities within the catchment areas of the Comprehensive Health and Epidemiological Surveillance System from 2018 to 2020.InterVA-5 cause of deaths analytical tool was used to assign specific causes of death (COD). …”
Get full text

A multicenter, cross‐sectional analysis to assess the safety and usage pattern of brivaracetam in the management of partial‐onset seizure with BAEs—BREEZE study: A post‐hoc analysi... by Arvind Sharma, Krishnaprasad Korukonda, Amit Haldar, Usha Kant Misra, R. V. Anand, Yakshdeep Dave, Girish Kulkarni

“…The study was approved by central independent ethics committee. Descriptive and analytical statistics employed using SPSS version 29.0.1.0. …”
Get full text

A high number of tumor deposits (≥ 4) is an isolated predictor of local recurrence and distant metastasis in non-metastatic colorectal cancer: a single center study by Ahmed Bendari, Ebubekir Ucar, Alaa Bendari, Hamed Hammoud, FNU Kiran, Reham Al-Refai, Sunder Sham, Sanjay Kirshan Kumar, Ryan Des Jean, Manju Harshan

“…The aim of this study is to identify the different prognostic factors associated with tumor recurrence and distant metastasis in CRC. Design An analytical cross-sectional design was employed, and our hospital clinical and pathology databases were queried for non-metastatic CRC (stage I-III). …”
Get full text

Chronic Energy Deficiency and Its Determinant Factors among Adults Aged 18–59 Years in Ethiopia: A Cross-Sectional Study by Samuel Dagne, Yonatan Menber, Yosef Wassihun, Gedefaw Dires, Atitegeb Abera, Seteamlak Adane, Melese Linger, Zelalem T. Haile

“…Data were collected using a multistage stratified cluster sampling technique, and the analytic sample consisted of 9,280 adults aged 18–59 years. …”
Get full text

Elevations in D-dimer levels in patients with Plasmodium infections: a systematic review and meta-analysis by Suriyan Sukati, Kwuntida Uthaisar Kotepui, Frederick Ramirez Masangkay, Ching-Ping Tseng, Aongart Mahittikorn, Nsoh Godwin Anabire, Polrat Wilairatana, Kinley Wangdi, Hideyuki J Majima, Apiporn Thinkhamrop Suwannatrai, Wiyada Kwanhian Klangbud, Wanida Mala, Rujikorn Rattanatham, Manas Kotepui

“…According to the evaluated studies, patients with Plasmodium infections had higher D-dimer levels. A meta-analytic evaluation of D-dimer levels between patients with and without Plasmodium infections revealed a significant elevation of D-dimer in patients with infection, with high heterogeneity (SMD = 2.11, 95% CI = 0.59; 3.64, P = 0.007, I² = 98%, 6 studies, 1,418 participants, random-effects model). …”
Get full text

Risk factors for COVID-19 hospitalisations and deaths in Mexican children and adolescents: retrospective cross-sectional study by Mauricio Hernandez-Avila, Libny Martínez-Valdez, Vesta Richardson López Collada, Luis Enrique Castro-Ceronio, Ángela María Rodríguez Gutiérrez, Aurora Bautista-Márquez

“…Objective To describe the epidemiology and risk factors for hospitalisation and death in Mexican children under 18 years of age with COVID-19.Design Retrospective, cross-sectional and analytical study.Setting Mexican Ministry of Health open databases with COVID-19 cases occurred from 7 March 2020 to 30 September 2021.Participants Mexican children under 18 years of age with COVID-19.Main outcome measures COVID-19 hospitalisations and deaths were characterised by age group, sex, presence of pneumonia and comorbidities, intubation and intensive care unit admission, and institution that provided medical care. …”
Get full text

Beyond support: exploring the dynamic and static biomechanical changes induced by preventive ankle taping: a novel cross-sectional study by María Bravo-Aguilar, Vanesa Abuín-Porras, María Blanco-Morales, Carlos Romero Morales, Jaime Almazán-Polo, Jorge Hugo Villafañe, Lorena Canosa-Carro

“…Methods An observational, analytic, cross-sectional study was designed. Data from static and dynamic plantar pressures with a pressure platform and balance data assessed with the Y Balance Test (YBT) were analysed in 50 participants (age = 21.00 ± 2.34 years, weight = 71.11 ± 13.12 kg, height = 1.75 ± 00.9 m, BMI = 22.94 ± 2.50 kg/m2, foot size = 41.60 ± 3.00) with and without preventive functional taping for lateral ankle sprain (LAS). …”
Get full text

Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery by Arda Halu, Sarvesh Chelvanambi, Julius L. Decano, Joan T. Matamalas, Mary Whelan, Takaharu Asano, Namitra Kalicharran, Sasha A. Singh, Joseph Loscalzo, Masanori Aikawa

“…Conclusions Our network-based analytical framework integrating pharmacogenomics and cheminformatics (available at https://github.com/r-duh/Pathopticon ) provides a feasible blueprint for a cell type-specific drug discovery and repositioning platform with broad implications for the efficiency and success of drug development.…”
Get full text

Clinical validation of an artificial intelligence-based decision support system for diagnosis and risk stratification of heart failure (STRATIFYHF): a protocol for a prospective, m... by Prithwish Banerjee, Guy A MacGowan, Frans H Rutten, Iacopo Olivotto, Petar M Seferović, Jonathan Mant, Djordje G Jakovljevic, Oscar Fernandez, Josep Darbà, Nduka C Okwose, Jose Zamorano, Duncan Edwards, David Sinclair, Lazar Velicki, Amy Groenewegen, Lars S Maier, Dimitris Fotiadis, Sarah Jane Charman, Annamaria Del Franco, Maria Tafelmeier, Andrej Preveden, Cristina Garcia Sebastian, Amy S Fuller, Anne Pauline Nelissen, Petros Malitas, Aikaterini Zisaki, Zoran Bosnic, Petar Vracar, Fausto Barlocco, Marta Jiménez-Blanco Bravo, Nenad Filipovic, Bano Fatima, Williams Kate, Fornaro Alessandra, Milovancev Aleksandra, Ascanio Meritxell, Aguera Ainoa, Pičulin Matej, Flis Borut, Boucharas Dimitrios, Manousos Dimitris, Tsiknakis Manolis, Kassiotis Thomas, Sustersic Tijana, Milicevic Bogdan, Hobbs FD Richard, Kaagman Onno

“…We propose to address this global challenge by developing the STRATIFYHF artificial intelligence-driven decision support system (DSS), which uses novel analytical methods in determining the risk, diagnosis and prognosis of HF. …”
Get full text

Characteristics of base materials and acrylates used in removable prosthetics in dental practice (review) by Yu.I. Poliukhovych, A.Ye. Demkovych, Yu.I. Bondarenko, V.V. Shcherba, O.I. Lebid, K.M. Duda

“…Used methods: bibliographic and analytical. The relation between the properties of the materials from which the prosthesis is made and the mucous membrane of the prosthetic bed was revealed, and the direct dependence of the quality of the prosthesis, the period of wearing, and the level of oral hygiene was determined. …”
Get full text

Post-COVID-19 manifestations among college students: shedding the light on young adults’ health by Areej Abed Alkhormani, Reema Abdullah Alghamdi, Yara Abdulaziz Damdam, Maria Eissa Almaghrabi, Faisal F. Alamri, Muhammad Anwar Khan, Alqassem Y. Hakami

“…Therefore, the aim of this study was to determine the prevalence and characteristics of post-COVID-19 manifestations in young adults. Methods An analytical cross-sectional online questionnaire was distributed from July 2022 to July 2023 to health sciences students in Saudi Arabia. …”
Get full text

MLinvitroTox reloaded for high-throughput hazard-based prioritization of high-resolution mass spectrometry data by Katarzyna Arturi, Eliza J. Harris, Lilian Gasser, Beate I. Escher, Georg Braun, Robin Bosshard, Juliane Hollender

“…This refinement makes the analytical confirmation of the toxicologically most relevant features feasible, offering significant benefits for cost-efficient chemical risk assessment. …”
Get full text

Pharmacognostic analysis and antimalarial evaluation of quercetin in Ilex umbellulata bark using HPTLC, in vitro screening, molecular docking, and network pharmacology by James H. Zothantluanga, Dipak Chetia, Yasangam Umbon, T. C. Lalhriatpuii, Dhritiman Roy, Nidahun Lamare, Salem Lalvenhimi

“…In this study, we aim to develop the missing pharmacognostic parameters with modern analytical techniques and carry out multi-step computational studies to study the antimalarial potential of I. umbellulata. …”
Get full text

Thiazide-Associated Hyponatremia and Mortality Risk: A Cohort Study by Steven G. Achinger, Juan Carlos Ayus, Ambuj Kumar, Athanasios Tsalatsanis

“…Secondary outcomes include development of sepsis, pneumonia, urinary tract infection, cellulitis, myocardial infarction, stroke, congestive heart failure, ataxia, fall, and hip fracture. Analytical Approach: The design is a retrospective cohort study, propensity score matched. …”
Get full text

Preferences for and acceptability of long-acting HIV prevention products among pregnant and lactating women accessing health services in Kenya: a mixed method cross-sectional analy... by Vallery Ogello, Paul Mwangi, Zachary Kwena, Nicholas Thuo, Catherine Makokha, Emmah Owidi, Nelson Muteti, Catherine Kiptinness, Nelly R. Mugo, Kenneth Ngure

“…Inductive and deductive content analytic approaches were used for in-depth interviews. …”
Get full text

Evaluation of mechanical and thermal performance of jute and coconut fiber-reinforced epoxy composites with rice husk ash for wall insulation applications by Md. Ahtesham Akhter, Dipayan Mondal, Arup Kumar Debnath, Md. Ashraful Islam, Md. Sanaul Rabbi

“…Furthermore, the heat transfer analysis has been studied analytically by considering two types of wall insulation configurations (type 1 and type 2). …”
Get full text

Importance of EQA/PT for the detection of genetic variants in comprehensive cancer genome testing by Kazuyuki Matsushita, Takayuki Ishige, Kousuke Watanabe, Toshiaki Akahane, Akihide Tanimoto, Michiko Yoshimoto, Munekazu Yamakuchi, Teruto Hashiguchi, Yoshinaga Okugawa, Makoto Ikejiri, Toshikazu Yamaguchi, Tadashi Yamasaki, Mayu Takeda, Masaaki Hibi, Naoki Akiyama, Kaho Shimizu, Naonori Hashimoto, Hiroko Sato, Yoshinori Tanaka, Fumie Amari, the EQA working group of Japan Association for Clinical Laboratory Science(JACLS)

“…Therefore, 10% VAF in pre-analytic processing for DNA extraction from FFPE was critical for variant detection in CGP analysis. …”
Get full text