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1701
Molecular cloning and expression dynamics of Atrogin-1 in muscle tissue of Russian sturgeon (Acipenser gueldenstaedtii) under high salt stress
Published 2025-03-01“…The cDNA encoding the Russian sturgeon protein Atrogin-1 was successfully cloned, comprising 1472 bp and encoding 353 amino acid residues (with an open reading frame of 1062 bp). …”
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1702
SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer
Published 2025-01-01“…We investigated the role of the amino acid transporter SLC1A5 (ASCT2) and its association with BC subtypes and patient outcomes. …”
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1703
Effects of Artificial Compound Feed for Live Fish Feed on Growth Performance, Nutrient Composition, Digestive Performance, and Gut Microbiota of Giant Salamander (<i>Andrias davidi...
Published 2024-12-01“…The water content in the S group was significantly higher than that in the H group (<i>p</i> < 0.05), and the crude fat content was slightly higher, whereas other nutritional components showed no significant differences (<i>p</i> > 0.05). The analysis of amino acid composition found no significant differences among the three groups of Chinese giant salamanders (<i>p</i> > 0.05). …”
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1704
Protective potential of structural proteins of the SARS-CoV-2 virus in protecting against COVID-19
Published 2024-12-01“…The largest number of amino acid substitutions in the structural proteins of different SARS-CoV-2 variants was detected in glycoprotein S, the smallest — in nucleoprotein N. …”
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1705
Molecular-genetic bases of plumage coloring in chicken
Published 2019-05-01“…The basis for the formation of melanin is the aromatic amino acid tyrosine. The process of melano-genesis involves many loci, part of the complex expression of plumage color genes. …”
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1706
Effects of Fishmeal Substitution with Mealworm Meals (Tenebrio molitor and Alphitobius diaperinus) on the Growth, Physiobiochemical Response, Digesta Microbiome, and Immune Genes E...
Published 2024-01-01“…Whole-body proximate and amino acid compositions were not statistically different between treatments, while essential fatty acids, including linolenic, eicosapentaenoic acid, and homo-a-linolenic, were lower in fish fed 100% DMM. …”
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1707
Predicting the Most Deleterious Missense Nonsynonymous Single-Nucleotide Polymorphisms of Hennekam Syndrome-Causing CCBE1 Gene, In Silico Analysis
Published 2021-01-01“…The FT web server predicted amino acid residues involved in the ligand-binding site of the CCBE1 protein, and two of the substitutions (R167W and T153N) were found to be involved. …”
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1708
Effects and function of citric acid on fermentation quality and microbial community in sugarcane tops silage with high and low water-soluble carbohydrate content
Published 2025-01-01“…., Clostridium_sensu_stricto_12 and Paecilomyces) and animal pathogens, while amino acid metabolism was lower in high-WSC STS regardless of CA treatment. …”
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1709
Calcitonin Gene-Related Peptide (Cgrp), Adrenomedullin (Am), Amylin, And Calcitonin (Ct) Receptors And Overlapping Biological Actions
Published 2001-01-01“…CGRP, AM, amylin, and CT have in common N-terminal 6-7 amino acid ring structures linked by disulfide bridges and amidated C-termini required for biological activity. …”
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1710
Diversity in Adaptive Evolution of Methicillin-Resistant Staphylococcus aureus Clinical Isolates Under Exposure to Continuous Linezolid Stress in vitro
Published 2025-02-01“…A new mutation in the domain V region of 23S rRNA gene (C2404T) and one mutation in amino acid sequences of ribosomal protein (Met208Thr) were firstly identified among linezolid-resistant strains. …”
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1711
Effect of Swimming on Gut Microbiota and Inflammation in Colorectal Cancer Cells Transplanted Mice
Published 2022-06-01“…Metabolic pathways enrichment of functional genes in the model group was significantly higher than those in the swimming group in terms of infectious diseases, carbohydrate metabolism, parasitism, membrane transport, exogenous biodegradation and metabolism, drug dependence, immune diseases and other amino acid metabolic pathways (<italic>P</italic><0.05). …”
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1712
Role of Fcγ receptors in HER2-targeted breast cancer therapy
Published 2022-01-01“…An example of an approved anti-HER2 Fc-engineered chimeric mAb is margetuximab, which targets the same epitope as trastuzumab, but features five amino acid substitutions in the IgG 1 Fc domain that were deliberately introduced to increase binding to activating FcγRIIIa and decrease binding to inhibitory FcγRIIb (CD32B). …”
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1713
Nature's defense against emerging neurodegenerative threats: Dynamic simulation, PCA, DCCM identified potential plant-based antiviral lead targeting borna disease virus nucleoprote...
Published 2024-01-01“…The three top compounds coordinated with the protein's common amino acid residues at GLN 161, ARG 165, ILE 145, ILE 162, ILE 149, and VAL 229 during molecular docking, which implies that both lead compounds and the control ligand interact within the protein's shared active site. …”
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1714
Unraveling the interactive effect of opaque2 and waxy1 genes on kernel nutritional qualities and physical properties in maize (Zea mays L.)
Published 2025-01-01“…Abstract The mutant waxy allele (wx1) is responsible for increased amylopectin in maize starch, with a wide range of food and industrial applications. The amino acid profile of waxy maize resembles normal maize, making it particularly deficient in lysine and tryptophan. …”
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1715
Zwitterion Effect of Cow Brain Protein towards Efficiency Improvement of Dye-Sensitized Solar Cell (DSSC)
Published 2020-01-01“…From the XRD test results by increasing the concentration of cow brain protein in DSSC, the structure of amino acid crystals also increased and the crystal size increased with the largest crystal size of 42.25 nm at the addition of 75% of cow brain protein. …”
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1716
The Safety and Efficacy of the Repeated PRRT with [90Y]Y/[177Lu]Lu-DOTATATE in Patients with NET
Published 2021-01-01“…Patients were treated with [90Y]Y/[177Lu]Lu-DOTATATE (1 : 1) with mixed amino acid infusion for kidney protection. Toxicity was evaluated using the CTCAE 3.0 criteria. …”
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1717
Genetic Diversity, Repeat Motifs, and Natural Selection at the C-Terminal Knob-Associated Histidine Rich Protein (KAHRP) of Plasmodium falciparum Clinical Samples from Saudi Arabia
Published 2022-01-01“…Alignment and analysis of 441 C-terminal PfKAHRP-deduced amino acid sequences identified 5 genotypes (I–V) based on the decapeptide repeat arrangements (TKEASTSKEA, TKEASTSKGA, TKEASTTEGA, and TKEASTSKRA). …”
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1718
The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes
Published 2018-12-01“…Phylogenies of POPB and POPA based on both coding and amino acid sequences showed very different results: while POPA genes clearly reflected the phylogeny of the host species, POPB did not; strikingly, it formed a wellsupported monophyletic clade, despite that the species belong to different genera in disjunct families. …”
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1719
Phosphorylation of Bok at Ser-8 blocks its ability to suppress IP3R-mediated calcium mobilization
Published 2025-01-01“…Also, using mammalian cells that exclusively or predominately express IP3R1, to which Bok binds strongly, and a fluorescent Ca2+-sensitive dye or a genetically-encoded Ca2+ sensor, we explored how endogenous and exogenous Bok controls the Ca2+ mobilizing function of IP3R1, and whether Bok phosphorylation at Ser-8, or replacement of Ser-8 with a phosphomimetic amino acid, is regulatory. Results Our results confirm that Ser-8 of Bok is phosphorylated by cAMP-dependent protein kinase, and remarkably that phosphorylation can be detected with Bok specific antibodies. …”
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1720
Exploring Disparities in Gill Physiological Responses to NaHCO<sub>3</sub>-Induced Habitat Stress in Triploid and Diploid Crucian Carp (<i>Carassius auratus</i>): A Comprehensive I...
Published 2024-12-01“…Notably, diploid carp efficiently excrete excess BUN through purine metabolism, mitigating protein metabolism and amino acid imbalances caused by BUN accumulation. This enables them to allocate less energy for coping with external environmental stress, redirecting surplus energy toward growth and development. …”
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