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1141
iTRAQ-based quantitative proteomic analysis of herbicide stress in Avena ludoviciana Durieu
Published 2025-01-01“…Gene Ontology (GO) analysis revealed that these DEPs mainly consisted of proteins related to photosynthesis, respiration, amino acid synthesis and translation, secondary metabolite biosynthesis, defense proteins, and detoxification. …”
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1142
Exploring the Mechanism of <i>Clostridium autoethanogenum</i> Protein for Broiler Growth Based on Gut Microbiota and Serum Metabolomics
Published 2025-01-01“…In summary, incorporating CAP into the diet can increase the relative abundance of beneficial bacteria in the cecum and improve the feed conversion efficiency of broilers by enhancing amino acid and energy metabolism.…”
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1143
Metabolic reprogramming and immunological changes in the microenvironment of esophageal cancer: future directions and prospects
Published 2025-01-01“…Mounting evidence underscores the importance of modulating metabolic traits within the tumor microenvironment (TME) to augment anti-tumor immunotherapy.MethodsWe selected relevant studies on the metabolism of the esophageal cancer tumor microenvironment and immune cells based on our searches of MEDLINE and PubMed, focusing on screening experimental articles and reviews related to glucose metabolism, amino acid metabolism, and lipid metabolism, as well their interactions with tumor cells and immune cells, published within the last five years. …”
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1144
Effects of Different Cooking Methods on Nutritional Properties and Non-volatile Flavor Substances of Lyophyllum decastes
Published 2025-02-01“…The results showed that boiling significantly reduced the levels of polysaccharides, total phenols, protein, total dietary fiber, soluble sugar, free amino acid, and 5'-nucleotide flavor content. Conversely, baking was found to be the most effective method in preserving or even enhancing these nutritional and flavor profiles. …”
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1145
Analysis of Nucleotide Alterations in the E6 Genomic Region of Human Papillomavirus Types 6 and 11 in Condyloma Acuminatum Samples from Brazil
Published 2019-01-01“…In this way, despite the nucleotide alterations found, it was not possible to observe amino acid changes and variants grouping according to geographical region.…”
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1146
Quantitative proteomics and targeted metabolomics reveal the role of Cassia siamea L. extract in the response to high-fat diet-induced obesity in Drosophila
Published 2025-02-01“…CSE helped restore disrupted amino acid levels, particularly glutamine, alanine, and proline, indicating improved metabolic regulation. …”
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1147
Enhancement of systemic and lung-localized CD4<sup>+</sup> T-cell immune responses by truncation of NS1 protein of a seasonal live influenza vaccine strain
Published 2024-11-01“…The main objective of this study is to evaluate the immunogenic properties of the H1N1 seasonal LAIV strain by truncation of the NS1 protein to 126 amino acides. Materials and methods. Using reverse genetics technique, two H1N1 LAIV strains with full-length and truncated NS1 protein with three consecutive stop codons added after the 126th amino acid residue were obtained.C57BL/6J mice were immunized intranasally with the vaccine candidates, twice at a three-week interval. …”
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1148
Genomic and Pathogenic Characteristics of Virulent Newcastle Disease Virus Isolated from Chicken in Live Bird Markets and Backyard Flocks in Kenya
Published 2020-01-01“…Also, the polybasic amino acid sequence at the fusion-protein cleavage site had the motif 112RRQKRFV118. …”
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1149
Exometabolomic exploration of culturable airborne microorganisms from an urban atmosphere
Published 2025-02-01“…Bacteria exhibited proficiency in amino acid synthesis, while fungi were actively involved in amino acid metabolism, transcription, and expression processes. …”
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1150
Severe deviation in protein fold prediction by advanced AI: a case study
Published 2025-02-01“…AlphaFold is remarkable in this arena for its outstanding accuracy in modelling proteins fold based solely on their amino acid sequences. In spite of these remarkable advances, experimental structure determination remains critical. …”
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1151
Pharmacovigilance in veterinary profession
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1152
Comprehensive cDNA cloning and putative feature analysis of endogenous cellulases possessed by the Pacific oyster, Crassostrea gigas.
Published 2025-01-01“…An alignment of the amino acid sequences suggested the presence of at least endo-β-1,4-glucanase. …”
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1153
Synthesis and Characterization of a Gd-DOTA--Permeation Peptide for Magnetic Resonance Relaxation Enhancement of Intracellular Targets
Published 2003-10-01“…Based upon enhanced cellular uptake of permeation peptides with D -amino acid residues, an all-D Tat basic domain peptide was conjugated to DOTA and chelated to gadolinium. …”
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1154
Recent Advances in Potential Clinical Application of Ghrelin in Obesity
Published 2012-01-01“…Ghrelin is the natural ligand of the growth hormone secretagogue receptor (GHS-R1a). Ghrelin is a 28 amino acid peptide possessing a unique acylation on the serine in position 3 catalyzed by ghrelin O-acyltransferase (GOAT). …”
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1155
Genomic Changes in an Attenuated ZB Strain of Foot-and-Mouth Disease Virus Serotype Asia1 and Comparison with Its Virulent Parental Strain
Published 2014-01-01“…The results showed that attenuation may be brought about by 28 common amino acid substitutions in the coding region, with one nucleotide point mutation in the 5′-untranslated region (5′-UTR) and another one in the 3′-UTR. …”
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1156
Characteristic and effect analysis of protein and peptide in Cantonese cured meat processing
Published 2022-09-01“…Glu and His were the major amino acid. The approximate molecular weights of the sarcoplasmic proteins and myofibrillar proteins ranged from 31 kDa to 50 kDa and 66 kDa, respectively. …”
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1157
tRNA modifications: greasing the wheels of translation and beyond
Published 2025-12-01“…Transfer RNA (tRNA) is one of the most abundant RNA types in cells, acting as an adaptor to bridge the genetic information in mRNAs with the amino acid sequence in proteins. Both tRNAs and small fragments processed from them play many nonconventional roles in addition to translation. tRNA molecules undergo various types of chemical modifications to ensure the accuracy and efficiency of translation and regulate their diverse functions beyond translation. …”
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1158
Engineering of acyl ligase domain in non-ribosomal peptide synthetases to change fatty acid moieties of lipopeptides
Published 2025-01-01“…Abstract Cyclic lipopeptides (CLPs) produced by the genus Bacillus are amphiphiles composed of hydrophilic amino acid and hydrophobic fatty acid moieties and are biosynthesised by non-ribosomal peptide synthetases (NRPSs). …”
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1159
Stress, nutrients and genotype: understanding and managing asparagine accumulation in wheat grain
Published 2020-07-01“…Accumulation of high concentrations of the amino acid asparagine in its free (soluble, non-protein) form is an example of an undesirable outcome of stress for the nutritional quality and food safety of wheat because of its role as a precursor to acrylamide, a carcinogenic processing contaminant. …”
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1160
ICGenomics: A PROGRAM COMPLEX FOR ANALYSIS OF SYMBOL SEQUENCES IN GENOMICS
Published 2014-12-01“…Examples are: ChIP-seq analysis; functional annotation of gene regulatory regions in nucleotide and amino acid sequences; prediction of nucleosome positioning; and structural and functional annotation of proteins, including their allergenicity and evolution features. …”
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