Lactobacillus salivarius metabolite succinate enhances chicken intestinal stem cell activities via the SUCNR1-mitochondria axis by Danni Luo, Minyao Zou, Xi Rao, Mingping Wei, Lingzhi Zhang, Yuping Hua, Lingzi Yu, Jiajia Cao, Jinyi Ye, Sichao Qi, Huanan Wang, Yuling Mi, Caiqiao Zhang, Jian Li

“…The results indicate that the administration of Lactobacillus salivarius supernatant to laying hens notably increased the mRNA abundance of the amino acid transporters oligopeptide transporter 1 (PepT1) and sodium-dependent neutral amino acid transporter (B0AT). …”
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Smad1 Promotes Tumorigenicity and Chemoresistance of Glioblastoma by Sequestering p300 From p53 by Lingli Gong, Daxing Xu, Kaixiang Ni, Jie Li, Wei Mao, Bo Zhang, Zhening Pu, Xiangming Fang, Ying Yin, Li Ji, Jingjing Wang, Yaling Hu, Jiao Meng, Rui Zhang, Jiantong Jiao, Jian Zou

“…Through molecular docking, it is discovered that Smad1 and p53 both interact with the acetyltransferase domain of p300, but at different amino acid sites. Disturbing the interface of Smad1 through amino acid mutations abolishes the Smad1‐p300 complex and promotes p53 acetylation. …”
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Patient-derived cornea organoid model to study metabolomic characterization of rare disease: aniridia-associated keratopathy by Ali Can Koc, Vedat Sari, Gamze Kocak, Tuba Recber, Emirhan Nemutlu, Daniel Aberdam, Sinan Güven

“…Conclusions This study emphasizes the profound impact of AAK mutations on metabolism, particularly in amino acid biosynthesis and energy metabolism pathways.…”
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α-methyltryptophan-mediated protection against diabetic nephropathy in db/db mice as studied with a metabolomics approach by Aimin Cai, Dingchao Shen, Qiushuang Xiong, Jie Ding, Yang Ding, Xinlu Lin, Lijia Chen, Qing Yao, Qing Yao, Guangyong Lin, Ruijie Chen, Vadivel Ganapathy, Vadivel Ganapathy, Longfa Kou

“…These disturbances are chiefly characterized by alterations in amino acid metabolism, energy production pathways, membrane biochemical features, and nicotinamide metabolism, all of which have been implicated in mTOR signaling and apoptotic pathways.DiscussionAdministration of α-MT to db/db mice showed evidence of IDO1 inhibition and rectification of metabolic dysfunctions with concurrent suppression of mTOR signaling and apoptosis. …”
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Human SLC26A1 Gene Variants: A Pilot Study by Paul A. Dawson, Pearl Sim, David W. Mudge, David Cowley

“…DNA sequence analyses showed missense mutations in seven patients: one individual was heterozygous R372H; 4 individuals were heterozygous Q556R; one patient was homozygous Q556R; and one patient with severe nephrocalcinosis (requiring nephrectomy) was homozygous Q556R and heterozygous M132T. The M132 amino acid in human SAT1 is conserved with 15 other species and is located within the third transmembrane domain of the predicted SAT1 protein structure, suggesting that this amino acid may be important for SAT1 function. …”
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The Influence of Neocate in Paediatric Short Bowel Syndrome on PN Weaning by E. De Greef, T. Mahler, A. Janssen, H. Cuypers, G. Veereman-Wauters

“…We recommend the use of an amino-acid-based formula to induce earlier weaning of PN.…”
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Effect of abattoir waste water on metabolic and antioxidant profiles of cowpea seedlings grown in crude oil contaminated soil by F. I. Achuba, M. O. Ja-anni

“…The concentrations of total sugar, total protein, total amino acid and β-carotene, chlorophyll, starch metabolizing enzymes as well as oxidative stress markers, lipid peroxidation, catalase, xanthine oxidase, aldehyde oxidase and superoxide dismutase were determined using standard methods. …”
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Digestibility of protein and estimated bioavailability of mineral compounds in plant-based yoghurt alternatives by Anastassia Zeinatulina, Kristel Tanilas, Kristel Ehala-Aleksejev, Ene Viiard, Tiina Kriščiunaite

“…This study evaluated the nutritional quality of 25 commercial plant-based (PB) yoghurt alternatives (lupin-, soya-, oat-, coconut-based), focusing on protein digestibility and amino acid score and the content of the essential minerals calcium, iron, magnesium, and zinc. …”
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Clinical Manifestation and Phylogenetic Analysis of Peste des Petits Ruminants in Local Iraqi Breed Sheep in Al-Diwaniyah Province by Khalefa A. Mansour, Muthanna H. Hussain, Saad H. Al-Husseiny, Asaad J. Abid, Qassim H. Kshash

“…Moving from a smaller hydrophobic amino acid to one with a bigger side chain may reduce protein stability. …”
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The Effect of Fish Oil-Based Lipid Emulsion and Soybean Oil-Based Lipid Emulsion on Cholestasis Associated with Long-Term Parenteral Nutrition in Premature Infants by Leilei Wang, Jing Zhang, Jiejin Gao, Yan Qian, Ya Ling

“…Analysis was made on the gender, feeding intolerance, infection history, birth weight, gestational age, duration of parenteral nutrition, total dosage of amino acid, age at which feeding began, usage of lipid emulsions, and incidence of cholestasis between the two groups. …”
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Preparation and Assessment of Surface and Functional Properties of Protein Blends from Moringa oleifera and Monodora myristica Seeds by A. E. Samuel, Y. B. Hyeladzira, S. I. Hussaina, F. Muhammad, Y. K. Adamu, N. Halliru, S. Mukhtar

“…The protein blends showed thixotropic behavior at elevated concentration and presented 1MOI:1MMI blend with the highest values of 9.75%, 22.47%, 32.11%, 60.21% and 72.09% for polar, basic, acidic, hydrophilic and non-essential amino acid distributions respectively. In contrast, 1MOI:2MMI and 2MOI:1MMI blends showed higher essential, aliphatic, aromatic, hydrophobic and non-polar amino acid distributions albeit lower in the former. …”
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The effect of homocysteine and homocystine protonation on double-layer parameters at the electrode/chlorates(VII) interface by Agnieszka Nosal-Wiercińska, Małgorzata Wiśniewska, Mariusz Grochowski, Waldemar Kaliszczak, Sławomira Skrzypek, Mariola Brycht, Dariusz Guziejewski, Wojciech Franus

“…It seems that the changes in E z and γ z values accompanying the change in the amino acid protonation in the basic electrolyte solution, confirm the altered arrangement of the cysteine mercury thiolates on the electrode surface.…”
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Potential Antidepressant Effects of Omeprazole Introduced Through Network Analysis and Systems Biology Should Be Interpreted with Caution in the Clinical Environment by Seyed-Ali Mostafavi

“…These alterations could affect protein/amino acid malnutrition and eventually lead to increased signs of depression. …”
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Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking by Ya-Li Wang, Guang Hu, Qian Zhang, Yu-Xiu Yang, Qiao-Qiao Li, Yuan-Jia Hu, Hua Chen, Feng-Qing Yang

“…However, the other two compounds lithospermic acid and salvianolic acid A had a weak effect on TYR, as they do not combine with the active amino acid residues or act on the active center of TYR. …”
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Helicobacter pylori promotes intestinal flora imbalance and hepatic metabolic disorders under arsenic stress by Linmin Zhong, Qiling Yang, Yiming Shao, Shanwen Hu, Lianxian Guo

“….), and metabolic potential of the intestinal microflora (amino acid metabolism and energy metabolism) in the combinatory exposure group. …”
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Investigating the Impact of HTNV Infection on the Gut Microbiota of Wild-Type and NLRX1 Knockout Mice by Wenjie Sun, Yaxin Ding, Ziyu Liu, Shiyuan Hou, Danni Sun, Ruixue Ma, Huarui Kang, Xiaohan Ma, Jiayu Wang, Hongrui Mu, Yunhua Lv, Tianle Gu, Qikang Ying, Fang Wang, Xingan Wu, Rongrong Liu

“…In addition, a comprehensive analysis of serum metabolomics revealed that differential metabolites were mainly concentrated in amino acid metabolism and lipid metabolism. Amino acid metabolism mainly involves arginine, lysine, and histidine metabolism, while lipid metabolism is mainly related to glycerophospholipid metabolism and fatty acid synthesis. …”
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Genomic characterization and evolutionary analysis of a Getah virus variant from piglets in central China by Zhenhua Guo, Yao Jiang, Peng Li, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang, Gaiping Zhang

“…Besides, six amino acid sites were under positive selection of E2 protein. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Transcriptomic analysis suggests that overexpression of TaMGD influenced multiple metabolic pathways in response to high-temperature stress, including carbon metabolism, amino acid metabolism, photosynthesis, and lipid-related metabolism. …”
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Docking Studies of Binding of Ethambutol to the C-Terminal Domain of the Arabinosyltransferase from Mycobacterium tuberculosis by Guillermo Salgado-Moran, Rodrigo Ramirez-Tagle, Daniel Glossman-Mitnik, Samuel Ruiz-Nieto, Pran Kishore-Deb, Marta Bunster, Francisco Lobos-Gonzalez

“…The complex shows that location of the Ethambutol coincides with the cocrystallization ligand position and that amino acid residues ASH1051, ASN740, ASP1052, and ARG1055 should be critical in the binding of Ethambutol to C-terminal domain EmbC.…”
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1H and 13C NMR Assignments of Cytotoxic 3S-1,2,3,4-Tetrahydro-β-carboline-3-carboxylic Acid from the Leaves of Cichorium endivia by Fu-Xin Wang, An-Jun Deng, Jin-Feng Wei, Hai-Lin Qin, Ai-Ping Wang

“…An amino acid, 3S-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid, was isolated for the first time from the leaves of Cichorium endivia. …”
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