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861
Effect of ionic strength and mixing ratio on complex coacervation of soy protein isolate/Flammulina velutipes polysaccharide
Published 2023-01-01“…Soy protein isolate (SPI) is a commercial protein with balanced amino acids, while the poor solubility impedes its use in traditional foods. …”
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862
Hydrolyzed Collagen from Salmon Skin Increases the Migration and Filopodia Formation of Skin Keratinocytes by Activation of FAK/Src Pathway
Published 2021-09-01“…HCSS had a high content of hydrophobic amino acids and imino acids. HaCaT cell proliferation and migration were significantly increased in response to HCSS at the concentration of 100-1000 μg/mL. …”
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863
Metabolomics combined with physiology and transcriptomics reveal the regulation of key nitrogen metabolic pathways in alfalfa by foliar spraying with nano-selenium
Published 2025-01-01“…The transcriptome and metabolome revealed that nano-selenium mainly affected the pathways of ‘biosynthesis of amino acids’, ‘starch and sucrose metabolism’, ‘pentose and glucuronate interconversions’, ‘pentose phosphate pathway’, and ‘flavonoid biosynthesis’. …”
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864
Repurposing brucine as a chemopreventive agent in mammary gland carcinoma: Regulating lactate transport through MCT-4
Published 2025-06-01“…BRU demonstrated strong affinity for the MCT-4 transporter's catalytic domain, forming significant hydrophobic and polar interactions with essential amino acids at the binding site. BRU demonstrated significant cytotoxicity and increased the extracellular lactate levels in MCF-7 cells. …”
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865
Phycospheric Bacteria Alleviate the Stress of Erythromycin on <i>Auxenochlorella pyrenoidosa</i> by Regulating Nitrogen Metabolism
Published 2025-01-01“…Metabolic functions, such ABC transporters, the microbial metabolism in diverse environments, and the biosynthesis of amino acids, were significantly upregulated in the treatments of higher concentrations (1.0 and 10 mg/L). …”
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866
Diet management of older subjects with Oropharyngeal Dysphagia: The efficacy of ready-made texture-modified and fortified meals
Published 2025-02-01“…This study investigated whether the ready-made texture-modified meals, fortified with amino acids and Vitamin D, may guarantee safe and efficient management of meals in older subjects with OD and facilitate patient management. …”
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867
Integrated Transcriptomic and Targeted Metabolomic Analysis Reveals the Key Genes Involved in Triterpenoid Biosynthesis of <i>Ganoderma lucidum</i>
Published 2025-01-01“…The results showed that a total of 699 components were detected, including lignans, terpenoids, amino acids and derivatives, and phenolic acids, among others. …”
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868
Ginkgo biloba extract EGb761 mitigates ischemic stroke via metabolic pathway modulation
Published 2025-01-01“…Conclusion: The ginkgo biloba extract EGb761 demonstrates anti-ischemic stroke effect on ischemic stroke model rats by regulating amino acids and amino acid derivatives, such as isoleucine, N6-acetyllysine, glutamate, methionine, and N,N-dimethylglycine.…”
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869
A bioinformatics approach for identifying the probable cause of the cross-interaction of antibodies to the antigenic protein HPV16 L1 with the HPV6 L1 protein
Published 2021-12-01“…There is a difference in only one position, but it is not critical due to the similarity of the physicochemical properties of amino acids, for which there is a replacement in the amino acid sequence of antigenic determinants. …”
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870
A variant in GRN of Spanish origin presenting with heterogeneous phenotypes
Published 2025-01-01“…Ex vivo splicing assays confirmed that the mutation c.1414-1G>T affects the splicing of the exon, causing a loss of 20 amino acids in exon 11. Conclusions: We conclude that variant c.1414-1G>T of the GRN gene is pathogenic, can lead to a variety of clinical presentations and to gene dosage effect, and probably has a Spanish founder effect. …”
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871
VdPAT1 encoding a pantothenate transporter protein is required for fungal growth, mycelial penetration and pathogenicity of Verticillium dahliae
Published 2025-01-01“…In previous study, we identified a pantothenate transporter gene (VdPAT1) in V. dahliae which can be induced by root exudates from a susceptible cotton variety.MethodsIn this study, we generated VdPAT1 deletion mutants and complementary strain via homologous recombination by a PEG-mediated transformation method and used for the gene functional characterization.Results and discussionThe VdPAT1 deletion mutants displayed reduced colony growth, melanin production, spore yield and germination rate, showed abnormal mycelial branching and decreased ability of mycelial penetration and utilization of nutrients (carbon, amino acids and vitamin), leading to a lower pathogenicity. …”
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872
Drought Adaptation and Responses of Stipa krylovii Vary Among Different Regions: Evidence From Growth, Physiology, and RNA‐Seq Transcriptome Analysis
Published 2025-01-01“…By KEGG functional enrichment analysis, individuals from the eastern and middle regions mainly regulated energy metabolism and metabolism of other amino acids; and those from the western region mainly regulated biosynthesis of other secondary metabolites and carbohydrate metabolism. (3) Clustering analysis based on gene expressions separated the western region from the other two regions under the same drought treatment. …”
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873
Designing multi-epitope vaccines against Echinococcus granulosus: an in-silico study using immuno-informatics
Published 2024-12-01“…The majority of the amino acids were positioned in the Ramachandran plot’s favourable area, and during the molecular dynamic simulation at 100 ns, no notable structural abnormalities were noticed. …”
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874
Effects of Different Tea Varieties on the Quality of Enshi Yulu Tea
Published 2024-12-01“…To investigate the effects of tea varieties on the quality of Enshi Yulu tea, 10 main tea cultivars (Fuyun 6, Echa 1, Chunbolü, Zhenong 117, Longjing 43, Wuniuzao, Zhongcha 108, Echa 10, Zhuyeqi, and Fuding Dabai) grown in Enshi were processed into Yulu tea, which was then evaluated for sensory quality, major physicochemical quality components (tea polyphenols, free amino acids, water extracts, and chlorophylls), dry tea color parameters (L*, a*, and b*), and volatile components. …”
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875
Dynamical Hybrid System for Optimizing and Controlling Efficacy of Plant-Based Protein in Aquafeeds
Published 2021-01-01“…Besides, ADC of crude lipid for RM-Yeast and RM-Koji, on the one hand, and ADC of gross energy for RM-Yeast, on the other hand, were not varied from that for FM (P>0.05). Amino acid digestibility reflects protein digestibility in most cases. …”
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876
Integrated metabolomics and proteomics analysis to provide insights into muscle atrophy of turbot Scophthalmus maximus by dietary Clostridium autoethanogenum protein
Published 2025-03-01“…Finally, the up-regulated AAR induced amino acids catabolism through purine-based combined deamination. …”
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877
CDK12 antagonizes a viral suppressor of RNAi to modulate antiviral RNAi in Drosophila
Published 2025-01-01“…In this study, cyclin-dependent kinase 12 (CDK12) was identified to interact with B2, a VSR of Flock House virus (FHV), and the critical amino acids responsible for dsRNA binding and dimerization in B2 were essential for this interaction. …”
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878
Differences in the Quality Components of Wuyi Rock Tea and Huizhou Rock Tea
Published 2024-12-01“…Biochemical experiments showed that HT was the highest in water leachables, about 43.12%; WT was the highest in tea polyphenols, about 14.91%; WR was the highest in free amino acids, about 3.38%; and the six rock teas had different health benefits. …”
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879
TaWI12 may be involved in pistillody and leaf cracking in wheat
Published 2025-01-01“…The open reading frames (ORFs) of TaWI12-4A, TaWI12-4B and TaWI12-4D were 408 bp, 417 bp and 417 bp, respectively, and encoded 135, 138 and 138 amino acids, respectively. The phylogenetic tree revealed a high degree of homology between the protein sequences of TaWI12 and the wound-induced proteins of Hordeum vulgare (KAI4994568) and Aegilops tauschii (XP_020196548). …”
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880
Is The SARS-CoV2 Evolved in Human Being: A prospective Genetic Analysis
Published 2020-12-01“…The evolutionary changes observed in the inserted 23 amino acids in the RNA binding domain (RBD) of the coronvirus spike glycoprotein which cannot be detected in any other human coronavirus. …”
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