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581
Application of a sourdough type-II fermentation model to gelatinized legume flours: Starter robustness, technological and nutritional implications, potential of the bread and pasta...
Published 2025-06-01“…However, after the fifth propagation cycle, there was a decline in the dominance of starter cultures, which negatively impacted the concentration of free amino acids and protein digestibility in the breads. …”
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582
Coupling Strategies for the Synthesis of Peptide-Oligonucleotide Conjugates for Patterned Synthetic Biomineralization
Published 2011-01-01“…The peptide, selected from a combinatorial library for its gold-binding behavior, was 12 amino acids long with an N-terminus acetyl cap. Formation of the conjugates was confirmed by gel electrophoresis and mass spectrometry while molecular recognition functionality of the peptide portion was verified using atomic force microscopy. …”
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583
Protein enrichment in instant pudding with fish protein hydrolysate (FPH) from trash fish
Published 2024-01-01“…Fish Protein Hydrolysate (FPH) from trash fish is a product derived from fish through the process of protein hydrolysis, into smaller protein, including peptides and eventually amino acids. The FPH is used to enhance the characteristics of various food products, such as to amino acid profiles, and improve nutritional content. …”
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584
Ligand-Based Pharmacophore Modeling and Virtual Screening of RAD9 Inhibitors
Published 2013-01-01“…The results revealed that camptothecin can act as an effective inhibitor among all the ligands taken and can be used as an RAD9 inhibitor. The amino acids ARG45 and ALA134 of RAD9 protein are interacting commonly with the drugs and BCL-2 protein.…”
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585
Chemo-selective modification of cysteine residue: synthesis and application in the discovery of potential drug candidates
Published 2024-09-01“…Chemo-select modification of peptides, targeting a handful of the most reactive proteinogenic amino acids (AAs), is gradually utilized to address the medical needs of peptide drugs and biopharmaceuticals. …”
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586
Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell
Published 2025-01-01“…Trisindoline 5 can inhibit EGFR binding site on some amino acids and forms hydrogen bonds that predicted to be more stable. …”
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587
Effect of Low-Frequency Ultrasonic-Assisted Enzymolysis on the Physicochemical and Antioxidant Properties of Corn Protein Hydrolysates
Published 2017-01-01“…Molecular weight distribution and amino acid profile analysis showed that ultrasound pretreatment enhanced the formation of short-chain peptides with molecular weight of 200–3000 Da, especially the peptides containing hydrophobic amino acids. …”
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588
Arabidopsis 3‐Deoxy‐d‐Arabino‐Heptulosonate 7‐Phosphate (DAHP) Synthases of the Shikimate Pathway Display Both Manganese‐ and Cobalt‐Dependent Activities
Published 2025-01-01“…ABSTRACT The plant shikimate pathway directs a significant portion of photosynthetically assimilated carbon into the downstream biosynthetic pathways of aromatic amino acids (AAA) and aromatic natural products. 3‐Deoxy‐d‐arabino‐heptulosonate 7‐phosphate (DAHP) synthase (hereafter DHS) catalyzes the first step of the shikimate pathway, playing a critical role in controlling the carbon flux from central carbon metabolism into the AAA biosynthesis. …”
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589
Synthesis, docking, pharmacokinetic prediction, and acetylcholinesterase inhibitory evaluation of N-(2-(piperidine-1-yl)ethyl)benzamide derivatives as potential anti-Alzheimer agen...
Published 2024-12-01“…Docking studies were also performed to investigate the binding mode and determine the interacting amino acids with the corresponding ligands. Finally, the pharmacokinetic (ADME parameters) of the most potent derivative (5d) was predicted and compared with donepezil. …”
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590
An Enhanced GC/MS Procedure for the Identification of Proteins in Paint Microsamples
Published 2018-01-01“…Using DMF, the formation of artifacts is limited and the derivatization yield of hydrophilic amino acids such as proline and hydroxyproline has improved, thus making the identification of organic paint media more straightforward. …”
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591
LC-MS/MS-based proteomics and metabolomics of HCT-116 colorectal cancer cells: A potential anticancer activity of atorvastatin
Published 2025-01-01“…Compared to the control, atorvastatin significantly altered numerous metabolites in HCT-116 cells, including a reduction in the levels of decanoylcarnitine and octanoyl-L-carnitine and in the biosynthesis and metabolism of amino acids like alanine and citrate cycle. Proteomic study showed that atorvastatin-treated HCT-116 cells expressed 127 proteins differently from controls. …”
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592
Skin Lesions Associated with Nutritional Management of Maple Syrup Urine Disease
Published 2017-01-01“…Maple syrup urine disease (MSUD) is an inborn error of branched chain amino acids (BCAAs) metabolism. We report an infant with MSUD who developed 2 episodes of cutaneous lesions as a result of isoleucine deficiency and zinc deficiency, respectively. …”
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593
Impact of Power Ultrasound on Antihypertensive Activity, Functional Properties, and Thermal Stability of Rapeseed Protein Hydrolysates
Published 2017-01-01“…Compared to the hydrolysates obtained without sonication, the amino acid profile of ultrasound pretreated hydrolysates showed significant changes particularly in the proline content and hydrophobic amino acids with an increased rate of 2.47% and 6.31%, respectively. …”
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594
Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes
Published 2018-01-01“…NMR measurements revealed that levels of branched-chain amino acids (BCAAs) and the valine metabolite 3-hydroxyisobyturate were higher in T2DM and IGT groups and correlated with measures of insulin resistance and lipid metabolism. …”
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595
The Current Applications of Metabolomics in Understanding Endometriosis: A Systematic Review
Published 2025-01-01“…Significant alterations of lipids, amino acids, as well as other compounds were present in human and animal models. …”
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596
The Phytochemical Screening and Antioxidants Potential of Schoenoplectus triqueter L. Palla
Published 2020-01-01“…Important types of phytochemicals found in this species are alkaloids, proteins, amino acids, flavonoids, phenols, terpenoids, tannins, saponins, and carbohydrates. …”
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597
Evaluating Metabolic Profiling of Human Milk Using Biocrates MxP<sup>®</sup> QUANT 500 Assay
Published 2025-01-01“…Higher concentrations at the later lactation stages were found predominantly for amino acids and related compounds. <b>Conclusions:</b> The MxP Quant<sup>®</sup> 500 assay is a useful tool for HM metabolic profiling, minimizing analytical bias between matrices, and enhancing our ability to study milk as a biological system.…”
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598
Identification of a Gene Sharing a Promoter and Peroxisome Proliferator-Response Elements With Acyl-CoA Oxidase Gene
Published 2006-01-01“…GSPA encodes a protein of 161 amino acids that is enriched in 3T3-L1 cells. Even other gene pairs might be regulated through common sequence elements, and conversely it would be interesting how each gene is aptly regulated in clusters.…”
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599
Physiological, biochemical and genetic bases of amaranth (Amaranthus L.) breeding for food and feed purposes (a review)
Published 2020-12-01“…It is characterized by a high content of protein saturated with essential amino acids, especially lysine, and a large number of bioactive compounds, such as vitamin C, amaranthine, rutin, carotenoids, etc. …”
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600
A dual expression plasmid with Microcin B17 compatible with both prokaryotic and mammalian systems
Published 2025-06-01“…In this study, we evaluated the utility of microcin B17 (MccB17), a peptide consisting of 43 amino acids, in promoting DNA recombination within pgMAX-II, a dual expression plasmid for both prokaryotic and mammalian systems. …”
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