Effects of nasal corticosteroids on boosts of systemic allergen-specific IgE production induced by nasal allergen exposure. by Cornelia Egger, Christian Lupinek, Robin Ristl, Patrick Lemell, Friedrich Horak, Petra Zieglmayer, Susanne Spitzauer, Rudolf Valenta, Verena Niederberger

“…<h4>Background</h4>Allergen exposure via the respiratory tract and in particular via the nasal mucosa boosts systemic allergen-specific IgE production. Intranasal corticosteroids (INCS) represent a first line treatment of allergic rhinitis but their effects on this boost of allergen-specific IgE production are unclear.…”
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Persistence of IgE-associated allergy and allergen-specific IgE despite CD4+ T cell loss in AIDS. by Katharina Marth, Eva Wollmann, Daniela Gallerano, Portia Ndlovu, Ian Makupe, Rudolf Valenta, Elopy Sibanda

“…The aim of the study was to investigate whether HIV-infected patients with CD4 cell counts <200 cells/µl can suffer from symptoms of IgE-mediated allergy, produce allergen-specific IgE antibody responses and show boosts of allergen-specific IgE production. …”
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Analysis of specific IgE allergens in patients with urticaria and allergic rhinitis by REN Sun, WU Tingting, MIN Wei

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Food allergen sensitization patterns in psoriasis patients by A. A. Barilo, S. V. Smirnova, A. A. Sinyakov

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Prevalence of Allergen-Specific IgE Positivity and Serum Immunoglobulin E Concentrations of Allergens in Dogs with Suspected Allergic Dermatitis Using the Multiple Allergen Simultaneous Test in South Korea by Yoon-Seok Jang, Jae-Il Han, Eun-Soo Lee, Doo-Sung Cheon, Aryung Nam, Jae-Eun Hyun

“…Dogs are diagnosed with allergic dermatitis based on history, clinical signs, and allergen-specific IgE detection. Using the multiple allergen simultaneous test (MAST)–immunoblot assay, this study measured IgE concentrations and analyzed the proportion of dogs showing allergen-specific IgE positivity, and IgE concentrations of environmental and food allergens in South Korea. …”
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Elucidation of Desensitization Mechanisms Induced by Oral Immunotherapy in a Rat Model of Ovalbumin Allergy by Daigo Takizawa, Tomoharu Yokooji, Chika Miyamoto, Yuki Koga, Keisuke Oda, Ryohei Ogino, Takanori Taogoshi, Hiroaki Matsuo

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High risk of asthma among early teens is associated with quantitative differences in mite and cat allergen specific IgE and IgG4: a modified Th2 related antibody response revisitedResearch in context by Thomas A. Platts-Mills, Behnam Keshavarz, Jeffrey M. Wilson, Sheryl L. Rifas-Shiman, Samuel M. Ailsworth, Joanne E. Sordillo, Lisa Workman, Martin Chapman, Jonas Lidholm, Emily Oken, Diane R. Gold

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Murine model of cross-IgE sensitization and cross-anaphylactic reactions among multiple group food allergens by Ibrahim Musa, Fariba Ardalani, Nan Yang, Soheila J. Maleki, Xiu-Min Li, Xiu-Min Li, Xiu-Min Li

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T follicular helper and memory B cells in IgE recall responses by Joshua F.E. Koenig

“…Lifelong allergies are the result of persistent production of allergen-specific IgE. However, IgE antibodies and the plasma cells that secrete them tend to be short-lived. …”
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Allergen sensitization patterns: Allergic rhinitis with multimorbidity versus alone—A real‐world study by Ya‐Ting Li, Qi‐Qing Ye, Ya‐Xin Lu, Ke‐Xin Yang, Ping‐Ping Zhang, Chang Chen, Min Zhou, Pei‐Ying Feng, Zhuang‐Gui Chen

“…The risk of allergic multimorbidity also increases with specific allergen positivity and higher allergen‐specific IgE levels.…”
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Immunoregulatory Role of HLA-G in Allergic Diseases by Giuseppe Murdaca, Paola Contini, Simone Negrini, Giorgio Ciprandi, Francesco Puppo

“…Elevated levels of soluble HLA-G (sHLA-G) molecules are detected in serum of patients with allergic rhinitis to seasonal and perennial allergens and correlate with allergen-specific IgE levels, clinical severity, drug consumption, and response to allergen-specific immunotherapy. sHLA-G molecules are also found in airway epithelium of patients with allergic asthma and high levels of sHLA-G molecules are detectable in plasma and bronchoalveolar lavage of asthmatic patients correlating with allergen-specific IgE levels. …”
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FcgammaRIIb inhibits allergic lung inflammation in a murine model of allergic asthma. by Nilesh Dharajiya, Swapnil V Vaidya, Hiroki Murai, Victor Cardenas, Alexander Kurosky, Istvan Boldogh, Sanjiv A Sur

“…Allergic asthma is characterized by airway eosinophilia, increased mucin production and allergen-specific IgE. Fc gamma receptor IIb (FcgammaRIIb), an inhibitory IgG receptor, has recently emerged as a negative regulator of allergic diseases like anaphylaxis and allergic rhinitis. …”
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In vitro testing using immunocap provides reliable assessment of sensitizing patterns to local allergens in patients with rhinitis/asthma by Sujoy Khan

“…Total immunoglobulin E (IgE) and allergen-specific IgE levels were done using Phadia 100 (Thermo Fisher Scientific). …”
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Endotypes of allergic rhinitis and asthma accompanying food allergy by A. V. Klimov, P. Yu. Isaev, V. V. Klimov, V. S. Sviridova

“…61 people suffering from persistent allergic rhinitis and asthma accompanying food allergies were studied using case histories, the NHANES questionnaire, polyspecific serum levels, allergen-specific IgE, IL4, IFNg and IL10 assays, and allergy skin tests. …”
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Prevalence of Vitamin D Insufficiency/Deficiency and Their Role in Atopic Dermatitis Development and Course in Children by Tatiana S. Kashinskaya, Natalia V. Shakhova, Yrij F. Lobanov, Elena M. Kamaltynova

“…Many studies have shown that patients with AD have low concentration of 25(OH)D in blood associated with high concentration of allergen specific IgE (according to several reports). The analysis of low 25(OH)D concentration prevalence, association of vitamin D deficiency with AD severity and sensitization to allergens, and association of vitamin D disorders with risk of AD development is presented.…”
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Multi-biofluid metabolomics analysis of allergic respiratory rhinitis and asthma in early childhood by Chih-Yung Chiu, MD, PhD, Meng-Han Chiang, MS, Chieh-Ni Kuo, BS, Mei-Ling Cheng, PhD, Gigin Lin, MD, PhD

“…An integrative analysis of their associations with allergen-specific IgE levels in the context of allergic rhinitis and asthma were also assessed. …”
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Intratonsillar Immunotherapy: A Convenient and Effective Alternative to Subcutaneous Immunotherapy for Allergic Rhinitis by Tian Gu, Wei Zhang, Lu Tan, Rong Xiang, Peiqiang Liu, Jingyu Huang, Qin Deng, Yuqin Deng, Zezhang Tao, Shiming Chen, Yu Xu

“…Prior to clinical trials, we analyzed tonsil samples from human subjects to assess immune responses, measuring interleukin-4 (IL-4), IL-21, total IgE (tIgE), and allergen-specific IgE concentrations using ELISA and BioIC. …”
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Molecular Allergy Diagnostics in Children with Cow’s Milk Allergy: Prediction of Oral Food Challenge Response in Clinical Practice by Maria Angela Tosca, Irene Schiavetti, Roberta Olcese, Chiara Trincianti, Giorgio Ciprandi

“…The aim of the study was to identify the cutoff value of serum allergen-specific IgE values able to predict a positive response to OFC. …”
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Evaluating the Pathogenic Potential of IgE Targeting Cross-Reactive Carbohydrate Determinants in Dogs by Thierry Olivry, Ana Mas Fontao, Laura Widorn, Ralf S. Mueller

“…Altogether, these results suggest that in dogs, as in humans, anti-CCD IgE are likely to have little pathogenic potential and blocking them in allergen-specific IgE serological tests is warranted to avoid false-positive results to plant extracts.…”
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Regulation of the IgE response by T follicular regulatory cells by Alexander L. Dent

“…Allergen-specific IgE is a major mediator of allergic responses and contributes greatly to allergic disease in the human population. …”
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