Insecticide resistance status and high frequency of kdr mutations in Aedes aegypti in Tegucigalpa, Honduras by Cindy Reyes-Perdomo, Denis Escobar, Luis Galo, Oscar Urrutia, Rita Lucrecia Vizcaino, Audrey Lenhart, Gustavo Fontecha

“…Frequencies of the F1534C and V1016I kdr alleles and their haplotypes were determined, and sequencing of the vgsc gene was performed for further genotyping. …”
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CYP2C19 PHARMACOGENETIC TESTING FOR PERSONALIZATION OF ANTIPLATELET THERAPY IN PATIENTS WITH ACUTE CORONARY SYNDROME IN ROUTINE CLINICAL PRACTICE by A. I. Akhmetova, E. B. Kleimenova, D. A. Sychev, O. V. Parshina, L. P. Yashina

“…PhGT results (detection of carriage of the CYP2C19*2 allele variant) was a significant predictor of antiplatelet therapy correction in ACS patients. …”
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PHARMACOGENETIC ASPECTS OF NEW ORAL ANTICOAGULANTS APPLICATION by A. V. Kryukov, D. A. Sychev, O. V. Tereshchenko

“…It is known the case of gastrointestinal bleeding in the carrier of allelic variants of ABCB1 gene rs2032582 and rs1045642 polymorphisms. …”
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Dissemination of a IncHI2A plasmid co-harboring the mcr-9 and bla NDM-1 genes in Israeli hospitals by Amos Adler, Stefany Ayala-Montaño, Mark V. Assous, Yuval Geffen, Sandra Reuter

“…Abstract The mcr-9 allele is typically located on IncHI2 type plasmids, but there are only few reports describing the co-occurrence of the bla NDM gene on the same plasmid. …”
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Integrated meta‐QTL and in silico transcriptome assessment pinpoint major genomic regions responsible for spike length in wheat (Triticum aestivum L.) by Changgang Yang, Xueting Zhang, Shihong Wang, Na Liu

“…The frequency of the elite allelic variation TaPP2C‐3B‐Hap II with high SL remained relatively stable at about 49.62% from the 1960s to 1990s. …”
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Human herpes viruses are associated with steeper age-dependent increases of serum biomarkers for dementia in cognitively unimpaired women by Lisa M. James, George Stratigopoulos, Apostolos P. Georgopoulos

“…These findings document a link between prior viral infection and dementia-related blood biomarkers, adding support to the HHV hypothesis in developing dementia, irrespective of apoE4 allele presence.…”
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HE DEPENDENCE OF IMMUNOGLOBULIN IGA AND IGE TEAR LEVELS FROM GLUTATHIONES-TRANSFERASE P1 GENE POLYMORPHISMS IN STEELWORKERS WITH OPHTHALMOPATHY by N. V. Mal’tseva, O. F. Lykova, M. A. Mel’nichenko, S. V. Arkhipova, A. L. Onishchenko

“…Genotyping was performed by means of allele-specific polymerase chain reaction, whereas ELISA technique was used for immune testing. …”
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FOXP3 and cholesterol 7α-hydroxylase variants: unraveling genetic links to multiple sclerosis and neuromyelitis optica by Aya Amir Nassef, Hebattalah Monir Mohammed Selim, Nevin Mohieldin Shalaby, Asmaa Ahmed Abdelrasool, Hend Hamed Tamim

“…The CYP7A1 wild AA genotype and A allele were more frequent in controls than in MS (p = 0.009, p = 0.041) and NMO patients (p = 0.016, p = 0.027). …”
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CYTOGENETIC EFFECTS OF TICK-BORNE TRANSMITTED CO- OR MONOINFECTIONS DEPENDING ON THE VARIANTS OF GLUTATHIONE-S-TRANSFERASE GENES (GSTM1 OR GSTT1) IN THE PATIENT’S GENOTYPE by N. N. Ilyinskikh, E. N. Ilyinskikh, E. V. Zamyatina, V. P. Zuevskiy

“…The significantly increased frequency of micronucleated cells was associated with the mutant inactive alleles of the GSTM1(0/0) and GSTT1(0/0) genes. If the patients were carriers of the mutant allele of the GSTM1(0/0) gene, the cytogenetic instability could persist for half a year. …”
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PREDICTIVE ROLE OF CONNEXIN 40 IN THE PATHOGENESIS OF HEREDITARY SICK SINUS SYNDROME by S. Yu. Nikulina, A. A. Chernova, V. A. Shulman, T. S. Kukushkina, M. I. Voevoda, V. N. Maksimov

“…Results. 71 SSS patients, 44 their healthy relatives, I-III degree of kinship, 197 subjects of control group were genotyped for the polymorphism of 44G>A of gene Cx40. According to allele-specific polymerase chain reaction 3 types of genotypes ADRA2B (II — homozygous wild, ID — heterozygous, DD — homozygous mutant) were found in SSS patients, their relatives and healthy subjects of control group. …”
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High-resolution detection of copy number alterations in single cells with HiScanner by Yifan Zhao, Lovelace J. Luquette, Alexander D. Veit, Xiaochen Wang, Ruibin Xi, Vinayak V. Viswanadham, Yuwei Zhang, Diane D. Shao, Christopher A. Walsh, Hong Wei Yang, Mark D. Johnson, Peter J. Park

“…Here, we introduce HiScanner (High-resolution Single-Cell Allelic copy Number callER), which combines read depth, B-allele frequency, and haplotype phasing to identify CNAs with high resolution. …”
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Association of <i>ABCG5</i> and <i>ABCG8</i> Polymorphisms with Gallstone Disease and Gallbladder Cancer by I. N. Grigor’eva, T. E. Notova, D. L. Nepomnyashchikh

“…The presence of the H allele D19H (rs11887534) is associated with a two-fold risk of recurrence of GSD after cholecystectomy. …”
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A short-chain dehydrogenase/reductase gene confers resistance to Verticillium wilt in cotton and reveals adaptive selection during domestication by Mubashir Abbas, Muhammad Jawad Umer, Aamir Ali Abro, Zhang Menghan, Chao Lu, Qiankun Liu, Heng Wang, Mengying Yang, Yiman Liu, Huang Wenjuan, Muhammad Aamir Khan, Muhammad Ali Abid, Muhammad Askari, Muhammad Aneeq Ur Rahman, Yuqing Hou, Jie Zhang, Yanchao Xu, Xiaoyan Cai, Zhongli Zhou, Rui Zhang, Fang Liu

“…Population genetic analysis revealed a favorable GhSDR500 allele selected during cotton domestication. A G > C mutation causing a glycine-to-alanine substitution in the NAD domain was identified, with the G allele strongly favored in modern cultivars due to its association with enhanced resistance. …”
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The role of VNTR aggrecan gene polymorphism in the development of osteoarthritis in women by D. A. Shapovalova, A. V. Tyurin, S. S. Litvinov, E. K. Khusnutdinova, R. I. Khusainova

“…We searched for associations between the VNTR locus and OA in general and with an account of the localization of the pathological process, as well as with the presence of uCTD signs. Twelve allelic variants and 24 genotypes of the VNTR polymorphism of the aggrecan gene (ACAN) were identified, the most frequent variants were alleles with 27, 28 and 26 repeats. …”
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Effect of HER2 Ile655Val polymorphism on the response to trastuzumab treatment in HER2-positive breast cancer patients by Zohreh Gheibipour, Tina Vosoughi, Gholamreza Shariati, Mehran Hoseinzadeh, Mohammad Reza Mahmoudian-Sani, Mahdi Bijanzadeh

“…The frequency of the G allele in treatment-responder and non-responder HPBC patients was 10.3% and 22.2%, respectively. …”
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The Role of Phosphatidylethanolamine-N-methyltransferase (PEMT) Gene rs12449964 Polymorphism in the Development of Acute Pancreatitis and its Complications by T. A. Samgina, Yu. E. Azarova, Yu. V. Kanishchev, V. A. Lazarenko, P. M. Nazarenko, A. V. Polonikov

“…The study has shown that the frequency of the C allele and the C/C PEMT C/T rs12449964 genotype was higher in the group of patients with acute pancreatitis, while the C/T genotype was predominant in the control group. …”
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Genetic Differentiation of Ornamental and Fruit-Bearing <i>Prunus laurocerasus</i> Revealed by SSR and <i>S</i>-Locus Markers by Attila Hegedűs, Péter Honfi, Sezai Ercisli, Gulce Ilhan, Endre György Tóth, Júlia Halász

“…The SSR loci amplified between 4 (ASSR63) and 17 (BPPCT039) alleles per accession, with eight of the 11 primers generating more than 12 alleles per accession. …”
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Association of TGF-β1 with periodontitis patients in north Indian population by Ruchi Pandey, Sumit Bhateja, Lipika Gopal, Ankita Chhabrani, Anju Rana, Puneet Batra

“…Correlation studies on gene polymorphism with the disease occurrence were carried out by estimating allele frequency, Hardy-Weinberg equilibrium (HWE), and chi-square test (GenAlex package), and linkage disequilibrium and haplotype analysis (SHEsis). …”
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Effect of ABCB1 Gene Carriage and Drug-Drug Interactions on Apixaban and Rivaroxaban Pharmacokinetics and Clinical Outcomes in Patients with Atrial Fibrillation and Deep Vein Throm... by L. V. Fedina, I. N. Sychev, T. D. Rastvorova, E. V. Strigunkova, A. A. Kachanova, Z. A. Sozaeva, P. O. Bochkov, A. V. Vardanyan, K. B. Mirzayev, D. A. Sychev

“…Our study revealed that the plasma concentration of rivaroxaban was higher in patients carrying the ABCB1 (rs4148738) C&gt;T polymorphism T allele. And patients taking apixaban together with CYP3A4/P-gp inhibitor had higher risk of hemorrhagic complications in comparison with patients not taking such drugs. …”
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THE POLYMORPHISM OF Α2B-ADRENERGIC RECEPTOR GENE — A NEW GENETIC MARKER OF THE HEREDITARY SICK SINUS SYNDROME by S. Iu. Nikulina, V. A. Shulman, A. A. Chernova, D. A. Nikulin, M. I. Voevoda, V. N. Maksimov

“…Genotypic examination of gene ADRA2B I/D polymorphism was performed in 213 individuals: 75 SSS-patients, 49 their healthy relatives, 89 healthy volunteers.Results. 3 types of ADRA2B genotypes (II — homozygous wild, ID — heterozygous, DD — homozygous mutant) were founded by allele-specific polymerase chain reaction. Significant prevalence of the homozygous genotype of more rare alleles DD in SSS-patients (28±5.2%) compared to the control group (8.99±3.0%) was found.Conclusion. …”
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