Piperine: Chemical, biological and nanotechnological applications by Quijia Christian Rafael, Araujo Victor Hugo, Chorilli Marlus

“…Piperine (PIP) is an alkaloid present in several species of piper, mainly Piper nigrum Linn. and P. longum, among other species. …”
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Molecular and cellular aspects of the impact of secondary metabolites from common barberry and hybrid goat’s rue on the HeLa cell line by E. Yu. Zlatnik, Ya. S. Enin, O. N. Burov, E. S. Bondarenko, A. B. Sagakyants, D. S. Kutilin, Yu. V. Dzigunova, O. G. Ishonina, E. V. Shalashnaya, N. D. Ushakova

“…All compounds used in the experiment exhibited a cytotoxic effect on the HeLa cell line. Berberine alkaloid showed the most pronounced cytotoxic effect on the HeLa line as recorded by all methods used in the study. …”
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INVESTIGATING CHOLAGOGUE AND CHOLERETIC ACTIVITY OF PEUMUS BOLDUS by Raphael S. F. Silva, Marcus Vinícius H. Faria, Joyce F. S. D. de Almeida, Tanos C. C. França

“…This study aimed to utilize molecular modeling and theoretical chemistry methods to contribute to the elucidation of the mechanism of action of boldine, an alkaloid present in the Peumus boldo plant. Boldo holds a special place in traditional medicinal practices throughout Brazil and has been officially recognized as medicinal plant. …”
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骆驼蓬总碱药理作用的研究 by 潘启超　杨小平　李春杰　胡海棠　利国威　曹　俊　许招懂　谢冰芬　潘伟光

“…摘　要　从骆驼蓬(Peganum harmala L .)种子中提取骆驼蓬总碱(total alkaloid of harmala, TAH)。实验 证明TAH 对6 种体外培养人癌细胞有强力细胞毒作用, 对3 种杂种鼠移植性肿瘤和3 种人癌裸鼠移植物有明 显抑瘤作用, 与顺铂或阿霉素有协同作用。…”
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Case report: Significant lesion reduction and neural structural changes following ibogaine treatments for multiple sclerosis by David Qixiang Chen, José Adalberto Inzunza Domínguez, Juan Manuel Valle Uzeta, Abhiram P. Pushparaj, Abhiram P. Pushparaj, Jonathan E. Dickinson

“…Ibogaine, a psychoactive alkaloid, has been proposed as a potential neuroregenerative agent due to its multifaceted pharmacological profile. …”
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Metabolite Profiling of Meridianin C In Vivo of Rat by UHPLC/Q-TOF MS by Guozhe Zhang, Linxia Xiao, Liang Qi

“…Meridianin C (MC), as a marine alkaloid, is a potent protein kinase inhibitor which exhibits good anticancer activity. …”
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Antibacterial and Oxacillin Resistance Reversing Effect of Harmaline in Different Strains of Staphylococcus Aureus by Zaid Ibraheem

“…Background: Harmaline is a naturally occurring indole alkaloid with many medicinal effects. Its antimicrobial effect against different pathogens has been reported previously.Objective: To explore the ability of harmaline to revers oxacillin resistance in the methicillin-resistant strain of Staphylococcus aureus (MRSA).Materials and methods: Briefly, 124 isolates of MRSA were procured from different wards of the Medical Complex City, Baghdad, Iraq. …”
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Anticalculi and antibacterial activity of methanol extract of Holothuria atra by Irwan Irwan, Jefri Saputra Mulia, Softyatuddin Karina, Eli Nurliza

“…Extraction was performed using the maceration method with methanol as the solvent over a period of 72 hours The analysis revealed the presence of four bioactive components in the methanol fraction: alkaloid, triterpenoids, flavonoids, and saponins. …”
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Antioxidant Activity of Methanol Extracts from Mangifera indica L., Mangifera foetida Lour, and Mangifera odorata Griff.Woods by Ganis Lukmandaru, Kristian Vembrianto, Anisa Alfiana Gazidy

“…Qualitative phytochemical tests of EtOAc soluble fractions indicated that alkaloid and tannin could contribute to the AOA results. …”
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Novel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA by Yi-ning Zhong, Yan Zhang, Yun-qiong Gu, Shi-yun Wu, Wen-ying Shen, Ming-xiong Tan

“…Tryptanthrin is one of the most important members of indoloquinoline alkaloids. We obtained this alkaloid from Isatis. Two novel FeII and CoII complexes of tryptanthrin were first synthesized. …”
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SKRINING FITOKIMIA DAN UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN SIRIH HITAM TERHADAP BAKTERI Escherichia coli by Florida Manek, Janrigo Klaumegio Mere, Sefrinus Maria Dolfi Kolo

“…Berdasarkan hasil skrining fitokimia, diketahui bahwa ekstrak etil asetat daun sirih hitam positif mengandung golongan senyawa steroid, alkaloid, dan tanin. Uji pada bakteri menunjukkan bahwa ekstrak etil asetat mampu menghambat pertumbuhan bakteri hingga kategori sangat kuat yaitu pada diameter 23,076 ± 0,04 mm pada konsentrasi 100%.…”
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Keefektivan Ekstrak Daun Sirih Hutan Sebagai Pengendali Serangan Hama Penggerek Buah Kopi (Hypothenemus hampei Ferrari) di Lapangan by John Agus Sahputra Pardosi, Arif Ravi Wibowo, Ebenezer Muaratama Sibarani

“…One such botanical pesticide is derived from the Piper aduncum L. plant, which contains various compounds including dilapiol, piperamidin alkaloid, flavonoids, saponins, steroids, polyphenols, tannins, and terpenoids. …”
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Severe Neurotoxicity due to Atropa belladonna Poisoning: A Case Report and Literature Review by Seyed Javad Boskabadi, Sima Ramezaninejad, Zakaria Zakariaei

“…The toxic effects of A. belladonna are attributable to its alkaloid content, which possesses potent anticholinergic properties. …”
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Stephania japonica Ameliorates Scopolamine-Induced Memory Impairment in Mice through Inhibition of Acetylcholinesterase and Oxidative Stress by Md. Yusuf Al-Amin, Amitav Lahiry, Rafia Ferdous, Md. Kamrul Hasan, Md. Abdul Kader, AHM Khurshid Alam, Zahangir Alam Saud, Md. Golam Sadik

“…The phytochemical profile revealed the high content of polyphenolics and alkaloids in the chloroform fraction. Pearson’s correlation studies showed a significant association of anticholinesterase and antioxidant activity with alkaloid and phenolic contents. …”
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Inhibitory Effect of Matrine on Blood-Brain Barrier Disruption for the Treatment of Experimental Autoimmune Encephalomyelitis by Su Zhang, Quan-Cheng Kan, Yuming Xu, Guang-Xian Zhang, Lin Zhu

“…Matrine (MAT), a quinolizidine alkaloid derived from the herb Radix Sophorae Flave, has been recently found to suppress clinical EAE and CNS inflammation. …”
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Inhibitory Effect of Aconitine on Colorectal Cancer Malignancy via Inducing Apoptosis and Suppression of Cell Motion by Xuehui Li, Jianglin Hu, Duan Tong, Taotao Yang, Ming Deng

“…Aconitine is a diester diterpenoid alkaloid that exhibits an antitumor role in several cancers. …”
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TOXICITY TEST OF LIME PEEL EXTRACT (Citrus aurantifolia) USING THE BRINE SHRIMP LETHALITY TEST (BSLT) METHOD FOR DETECTION OF ANTI CANCER ACTIVITY by Indah Khairunnisa, Endang Linirin Widiastuti, Nuning Nurcahyani

“…Based on phytochemical and FTIR tests, lime peel (C. aurantifolia) contains alkaloid, flavonoid, and tannin compounds which are known to have antioxidant properties and can disrupt the balance of Reactive Oxygen Species (ROS) so as to trigger apoptosis of cancer cells. …”
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Larvacide Activity of Tumih (Combretocarpus rotundatus (Miq.)Danser) Leaf Extracts against Aedes aegypti by Renhart Jemi, Royda Dara Ertini Damanik, Lies Indrayanti

“…Danser leaves contained alkaloids, flavonoids, saponins, and tannins. Larvicidal test conducted on the extracts exhibited an effect on the mortality levels against Aedes aegypti larvae. …”
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Computational Study of Trisindoline 5 Against Overexpressed EGFR Protein on Breast Cancer Stem Cell by Nurhayati A.P.D., Fatoni M., Santoso M., Wati F.A.

“…Trisindoline is an indole trimer alkaloid natural compound that provide a cytotoxic effect on cancer cells. …”
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Regulating the PI3K and AMPK pathway: the secret of 1-deoxynojirimycin's success in alleviating chronic diseases by Chengwei Yu, Qirui Hu

“…The 1-deoxynojirimycin (DNJ) is the unique alkaloid and the primary component for hypoglycemic effects in the mulberry leaves. …”
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