An Indole Alkaloid Extracted from Evodia rutaecarpa Inhibits Colonic Motility of Rats In Vitro by Guo-xiang Wang, Yan-li Xiang, Hong-gang Wang, Yang-de Miu, Guang Yu

“…Evodiamine (Evo) is an indole alkaloid extracted from the traditional Chinese medicinal herb Evodia rutaecarpa. …”
Get full text

Warifteine, an Alkaloid Purified from Cissampelos sympodialis, Inhibits Neutrophil Migration In Vitro and In Vivo by Thaline F. A. Lima, Juliana D. B. Rocha, Anderson B. Guimarães-Costa, José M. Barbosa-Filho, Débora Decoté-Ricardo, Elvira M. Saraiva, Luciana B. Arruda, Marcia R. Piuvezam, Ligia M. T. Peçanha

“…We investigated whether warifteine, its main alkaloid, would have anti-inflammatory effect due to a blockage of neutrophil function. …”
Get full text

New Steroid–Alkaloid Bioconjugates as Potential Bioactive Compounds: Synthesis, Spectroscopic and In Silico Study by Hanna Koenig, Karolina Babijczuk, Kamil Ostrowski, Damian Nowak, Tomasz Pospieszny, Beata Jasiewicz

Subjects: Get full text

Total syntheses of the parvistemoline alkaloids enabled by stereocontrolled Ir/Pd-catalyzed allylic alkylation by Xiao Liang, Qian-Hui Ding, Jian-Ting Yang, Hua-Fei Yang, Yi Deng, Li Shi, Kun Wei, Yu-Rong Yang

“…Abstract The functionalized polycycle with densely contiguous tertiary stereocenters is a formidable challenge in synthesizing the parvistemoline family of Stemona alkaloids. We herein report their catalytic, asymmetric total syntheses in 13–14 steps from commercially available 2-(methoxycarbonyl)-pyrrole, featuring the development and deployment of an Ir/Pd-synergistically-catalyzed allylation of α-non-substituted keto esters with secondary aryl-substituted alcohols, stereodivergently accessible to four stereoisomers. …”
Get full text

Vibrational Spectroscopic Study of the Cocrystal Products Formed by Cinchona Alkaloids with 5-Nitrobarbituric Acid by Harry G. Brittain

“…For the nitrobarbiturate cocrystals with cinchonine, cinchonidine, and quinidine, the predominant interaction was with the quinoline ring system of the alkaloid. However, for quinine, the predominant interaction was with the quinuclidine group of the alkaloid. …”
Get full text

Alkaloids of narrow-leaved lupine as a factor determining alternative ways of the crop’s utilization and breeding by M. A. Vishnyakova, A. V. Kushnareva, T. V. Shelenga, G. P. Egorova

Subjects: Get full text

Cryptolepine, the Main Alkaloid of the Antimalarial Cryptolepis sanguinolenta (Lindl.) Schlechter, Induces Malformations in Zebrafish Embryos by Kwesi Boadu Mensah, Charles Benneh, Arnold Donkor Forkuo, Charles Ansah

“…Previous studies on cryptolepine, the antimalarial and cytotoxic alkaloid of Cryptolepis sanguinolenta, showed that it preferentially accumulates in rapidly proliferating cells and melanin-containing tissues. …”
Get full text

Alkaloid Profile, Anticholinesterase and Antioxidant Activities, and Sexual Propagation in <i>Hieronymiella peruviana</i> (Amaryllidaceae) by Olimpia Llalla-Cordova, Javier E. Ortiz, Luciana R. Tallini, Laura Torras-Claveria, Jaume Bastida, Lorena Celina Luna, Gabriela E. Feresin

“…This work examines the alkaloidal profile using GC-MS and UPLC-MS/MS of alkaloid-enriched extracts obtained from the leaves and bulbs of <i>H. peruviana</i> and their inhibitory activity against acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) enzymes. …”
Get full text

In-vitro acaricidal activity of peganum harmala and glaucium flavum alkaloid against rhipicephalus sp. of dog by Rosa Kebbi, Omar Besseboua, Mohamed Nait-Mouloud, Abdelhanine Ayad

Subjects: “…alkaloid…”
Get full text

Antileishmanial Activity of Warifteine: A Bisbenzylisoquinoline Alkaloid Isolated from Cissampelos sympodialis Eichl. (Menispermaceae) by Eliete Cavalcanti da Silva, Cynthia Dias Rayol, Paloma Lys Medeiros, Regina Célia Bressan Queiroz Figueiredo, Márcia Regina Piuvezan, José Maria Brabosa-Filho, Alexsandro Fernandes Marinho, Teresinha Gonçalves Silva, Gardenia Carmen Gadelha Militão, Ana Paula Pimentel Cassilhas, Paulo Paes de Andrade

“…The bisbenzylisoquinoline alkaloids have been related to antibacterial, antiprotozoal, and antifungal activities. …”
Get full text

Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…In this context, we identified alkaloid fractions derived from PJLME (PJLME-AF) as key agents in PJLME's cytotoxic effect against melanoma cells. …”
Get full text

Stability of Alkaloids during Drying Process and Their Effect on Anticoagulating Activity of Uncariae Ramulus Cum Uncis by Lu Zou, Fengyu Lu, Bing Lin, Ying Zhou, Tingting Liu, Yue Sun

“…It was observed that the alkaloids content of URCU firstly showed a tendency of increasing and then decreasing after reaching the peak at the 570th minute in the process of constant temperature drying. …”
Get full text

Interaction of norsecurinine-type monomeric and dimeric alkaloids with α-tubulin: a molecular docking study by Gérard Vergoten, Christian Bailly

Subjects: Get full text

Antibacterial and antioxidant potentials, detection of host origin compounds, and metabolic profiling of endophytic Bacillus spp. isolated from Rauvolfia serpentina (L.) Benth. ex... by Rusi Lata, Surendra Kumar Gond

Subjects: “…Alkaloid…”
Get full text

Kajian Farmakoinformatika Senyawa Alkaloid Anggur Laut (Caulerpa racemose) Sebagai Inhibitor Collagenase Dalam Mekanisme Antiaging by Dewi Ratih Tirto Sari, M.Eko Pranoto, Siti Zamilatul Azkiyah

Subjects: “…alkaloid…”
Get full text

β-Carboline Alkaloids and Essential Tremor: Exploring the Environmental Determinants of One of the Most Prevalent Neurological Diseases by Elan D. Louis, Wei Zheng

“…Harmane (1-methyl-9H-pyrido[3,4-β]indole) is a potent, tremor-producing β-carboline alkaloid, and emerging literature has provided initial links between this neurotoxin and ET. …”
Get full text

An In Silico Study of the Interactions of Alkaloids from Cryptolepis sanguinolenta with Plasmodium falciparum Dihydrofolate Reductase and Dihydroorotate Dehydrogenase by Lois Kwane Kyei, Edward Ntim Gasu, Gilbert Boadu Ampomah, Jehoshaphat Oppong Mensah, Lawrence Sheringham Borquaye

“…Therefore, molecular docking and molecular dynamics simulations were used to investigate the interactions and stability of the alkaloids with PfDHFR and PfDHODH. Based on physicochemical characteristics, alkaloids were grouped as sterically bulky (sb) or planar (pg). …”
Get full text

Effects of typical plant growth regulator chlormequat chloride on alkaloidal compounds in Corydalis yanhusuo and molecular mechanisms by Zixuan Du, Jiayin Cao, Jie Meng, Heng Zhou, Qing Hu, Ling Li, Yun Liao, Shui Miao, Wenting Li, Shen Ji, Tongshuai Wang

“…Transcriptomic analysis also facilitates the identification of differential genes and enzymes associated with alkaloid production between the two groups. Chlormequat chloride significantly increased the yield of C. yanhusuo, but the content of the quantitatively abundant alkaloids decreased. …”
Get full text

First report of fatty acid-derived alkaloids produced by species of the ladybird genus Scymnus (Coccinellidae: Coleoptera) by Magro, Alexandra, Ramon-Portugal, Felipe, Touboul, David, Borges, Isabel, Hemptinne, Jean-Louis

“…The results of the GC-MS analyses suggest that Scymnus spp. produce azamacrolides, which are fatty acid-derived alkaloids.…”
Get full text

Virtual Screening, Toxicity Evaluation and Pharmacokinetics of Erythrina Alkaloids as Acetylcholinesterase Inhibitor Candidates from Natural Products by Permana A, Akili AWR, Hardianto A, Latip JB, Sulaeman AP, Herlina T

Subjects: “…erythrina alkaloid…”
Get full text