Aminoguanidine hemisulfate improves mitochondrial autophagy, oxidative stress, and muscle force in Duchenne muscular dystrophy via the AKT/FOXO1 pathway in mdx mice by Shiyue Sun, Tongtong Yu, Joo Young Huh, Yujie Cai, Somy Yoon, Hafiz Muhammad Ahmad Javaid

“…Methods Male wild-type (WT) and mdx mice were divided into three groups: WT, mdx, and AGH-treated mdx mice (40 mg/kg intraperitoneally for two weeks) at 6 weeks of age. Gene expression, western blotting, H&E staining, immunofluorescence, ROS assays, TUNEL apoptosis, glutathione activity, and muscle force measurements were performed. …”
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Effect of Graphene Warm Abduction Orthosis on Hip Joint Development in Children with Spastic Cerebral Palsy by CUI Meiyu, LIU Jianjun, ZHANG Yan, ZENG Fanyong

“…ObjectiveTo observe the effect of graphene warm abduction orthosis on hip joint development in children with spastic cerebral palsy.MethodsA total of 28 children (56 hips) aged 2-10 years with spastic cerebral palsy were randomly divided into two groups by random number table method. …”
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Diagnostic Accuracy Of Barium Swallow For Dysphagia, Keeping Rigid Esophagoscopy As The Gold Standard by Ansa Umara Akram, Sadia Chaudhry, Sundas Masood, Amna Kausar, Seema Naveed, Areesha Manzoor

“…Results: A total of 111 patients were included in this study. The mean age of these patients was 50.79 ± 13.01 years, ranging from 28 to 70 years. …”
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Karakteristik Pasien Penyakit Jantung Rematik yang Dirawat Inap di RSUP Dr. M. Djamil Padang by Marhamah Hasnul, Najirman , Yanwirasti

“…The result of this study showed that majority of the patients at the age group 11-20 years (50%), female (57.41%), elementary education degree/equal and junior high/equal of each 25.93%, students/university students (53.70%), and come from rural areas (70.37%). …”
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Comparison of different severe obesity definitions in predicting future cardiometabolic risk in a longitudinal cohort of children by Gilles Paradis, Melanie Henderson, Lisa Kakinami, Angelo Tremblay, Anna Smyrnova

“…Unfavourable blood pressure was defined as ≥90th percentile for age-adjusted, sex-adjusted and height-adjusted systolic or diastolic blood pressure.Analysis Area under the receiver operating characteristic curve (AUC) and McFadden psuedo R2 for predicting F1 or F2 unfavourable cardiometabolic levels from baseline SO definitions were calculated. …”
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An exploration of desired abstinent and non-abstinent recovery outcomes among people who use methamphetamine by Alex Elswick, Amanda Fallin-Bennett, Karen L. Roper, Evan Batty, Christopher J. McLouth, William Stoops, Hilary L. Surratt, Carrie B. Oser

“…Results Participants were primarily White (88%), male (67%), and an average age of 40. Approximately two-thirds of participants agreed that people need to stop all mood- or mind-altering substances to be in recovery (64%). …”
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The Validation of a Novel, Sex-Specific LDL-Cholesterol Equation and the Friedewald, Sampson-NIH, and Extended-Martin–Hopkins Equations Against Direct Measurement in Korean Adults... by Hyun Suk Yang, Soo-Nyung Kim, Seungho Lee, Mina Hur

“…<b>Methods:</b> This study included 23,757 subjects (51% male; median age, 51 years) from the 2009–2022 Korean National Health and Nutrition Examination Survey. …”
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Comparative effectiveness of manual therapy, pharmacological treatment, exercise therapy, and education for neck pain (COMPETE study): protocol of a systematic review with network... by Ana Izabela Sobral de Oliveira-Souza, Jordana Barbosa-Silva, Douglas P. Gross, Bruno R. da Costa, Nikolaus Ballenberger, Tiago V. Pereira, Liz Dennett, Susan Armijo-Olivo

“…Studies should include adults (aged > 18) with neck pain who received any of the interventions of interest (education, ET, MT, and medication). …”
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Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease. by Magdaléna Neřoldová, Elżbieta Ciara, Janka Slatinská, Soňa Fraňková, Petra Lišková, Radana Kotalová, Janka Globinovská, Markéta Šafaříková, Lucie Pfeiferová, Hana Zůnová, Lenka Mrázová, Viktor Stránecký, Alena Vrbacká, Ondřej Fabián, Eva Sticová, Daniela Skanderová, Jan Šperl, Marta Kalousová, Tomáš Zima, Milan Macek, Joanna Pawlowska, A S Knisely, Stanislav Kmoch, Milan Jirsa

“…(Lys56Thr) born to first cousins, had liver disease, interpreted on biopsy aged 4y as glycogen storage disease, followed by adult-onset nephronophthisis at 25y. …”
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Effects of a 16-week dance intervention on loneliness and self-esteem in left behind children: a randomised controlled trial by Xiaolin Li, Qian Yang, Jiayi Long, Linghui Zhou, Chunxia Lu, Zhenqian Zhou, Ming Zeng, Weixin Dong

“…Linear mixed-effects models for repeated measures were used to test the effects of time, group and time × group interactions. (a) The average age of the 1261 participants was 10 years (SD = 3.52), with high levels of loneliness (42.48 ± 12.04) and low levels of self-esteem (26.75 ± 6.39). …”
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Statut foncier et services écosystémiques fournis par les palmiers dattiers (Phoenix dactylifera L) des oasis du Kawar (Nord-Est du Niger) by Malam Moussa Dagrama, Tidjani Adamou Didier, Moustapha Moustapha Aboubacar, Elhadji Mohamoud Chekou Koré

“…Les oasis occupées essentiellement par les palmiers dattiers s’échelonnent à l’Est, le long de la falaise gréseuse, d’âge tertiaire. Elles supportent les activités économiques des populations locales en offrant de nombreux services écosystémiques en lien avec le palmier dattier. …”
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Dose-Weighted Network Pharmacology: Evaluating Traditional Chinese Medicine Formulations for Lumbar Disc Herniation by Zhou C, Xiang T, Yu Y, Ma H, Liu C, Yang F, Yang L

“…Changwen Zhou,1 Ting Xiang,2 Yu Yu,3 Hongzhong Ma,1 Ce Liu,1 Feng Yang,1,4,&ast; Lixue Yang1,4,&ast; 1The First Clinical Medical College, Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China; 2Rehabilitation Department, Xiang Xi Autonomous Prefecture National Hospital, Hunan, People’s Republic of China; 3Department of Chinese Medicine, Minda Hospital of Hubei Minzu University, Hubei, People’s Republic of China; 4Department of Orthopedic Hospital, The Affiliated Hospital of Shaanxi University of Chinese Medicine, Shaanxi, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Lixue Yang; Feng Yang, The First Clinical Medical College, Shaanxi University of Chinese Medicine, Vice No. 2, West Weiyang Road, Qindu District, Shaanxi, 712000, People’s Republic of China, Email ylx18391076233@163.com; yangfengdudu@163.comBackground and Purpose: Lumbar disc herniation (LDH) significantly impacts individuals, particularly those aged 40– 45. Traditional Chinese Medicine (TCM) formulations such as Taohong Siwu Decoction (TSD), Yaotong Jizheng Decoction (YJD), and Panlong Qi Tablet (PQT) are widely used for treatment. …”
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Impact of biological sex and gender-related factors on public engagement in protective health behaviours during the COVID-19 pandemic: cross-sectional analyses from a global survey by Simon L Bacon, Kim L Lavoie, Valeria Raparelli, Louise Pilote, Rubee Dev, Colleen M Norris

“…Multivariable logistic regression was conducted to determine the factors associated with non-adherence to behaviours.Results Among 48 668 respondents (mean age: 43 years; 71% female), 98.3% adopted hand washing, 68.5% mask wearing and 76.9% physical distancing. …”
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Transcranial Doppler sonography follow-up study in mild vascular cognitive impairment. by Mariagiovanna Cantone, Manuela Pennisi, Giuseppe Lanza, Raffaele Ferri, Francesco Fisicaro, Francesco Cappellani, Emanuele David, Vito Nicosia, Klizia Cortese, Giovanni Pennisi, Valentina Puglisi, Rita Bella

“…<h4>Methods</h4>From the original cohort of 161 patients, 127 with VCI (mean age 73.6 ± 7.1; 67 males) were re-evaluated after 5.0 ± 1.8 years. …”
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Epicutaneous immunotherapy for food allergy: a systematic review and meta-analysis by Xiaohong Xiang, Jingwei Hu, Rangui Sachu, Chonghua Gao, Hongyan Niu, Yi Gao, Shiju Chen, Xiaotian Cui, Xiang Li

“…The meta-analysis revealed that EPIT promoted desensitization in patients with food allergy (RR 2.11, 95% CI 1.72–2.58; I 2 = 0%, high certainty), particularly in aged ≤ 11 years (RR 3.84, 95% CI 2.39–6.26; I 2 = 34%). …”
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Systemic therapy a risk factor for glaucoma development and progression by A.M. Getmanova, A.Yu. Brezhnev, A.V. Kuroyedov, V.I. Baranov, A.S. Dvornikov

“…Dvornikov⁴</b> </p> <p> <b>¹Bryansk Regional Hospital, Bryansk, Russian Federation</b> </p> <p> <b>²Kursk State Medical University, Kursk, Russian Federation</b> </p> <p> <b>³Mandryka Military Clinical Hospital, Moscow, Russian Federation</b> </p> <p> <b>⁴Pirogov Russian National Research Medical University, Moscow, Russian Federation</b> </p> <p> <i>The prevalence of multimorbidity defined as the presence of two or more chronic diseases increases with ageing. Multimorbidity which is associated with a decline in the quality of life and functional abilities results in the increase in the rate of various physiological disorders and hospital treatment and, therefore, growing healthcare costs. …”
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Catlet scoring system as a new predictor for in-stent restenosis in patients with chronic coronary artery disease undergoing percutaneous coronary intervention with drug-eluting st... by Juan Wang, Mingchao Zhang, Weipeng Gan, Mingxing Xu, JiaYan Zhou, Lingfei Yang, Yongsheng Ke

“…Results A total of 165 patients (46 women and 119 men) with a mean ages of 66.19 ± 10.54 years were finally enrolled in this study. …”
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Improving Outcomes with Sequential Fixation Using Long-Threaded Screws for Valgus-Impacted Femoral Neck Fractures by Jeong-Hyun Koh, Seungyeob Sakong, Won-Tae Cho, Sumin Lim, Hyung Keun Song

“…<i>Materials and Methods:</i> This prospective study included 135 patients aged 60 years or older with valgus-impacted femoral neck fractures (OTA 31B1.1 and 31B1.2) treated between March 2017 and February 2021. …”
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Long-term Patency and Complications of Endovascular and Surgical Revascularization for Takayasu Arteritis by Jiyoung Shin, Ara Cho, Ahram Han, Sanghyun Ahn, Sangil Min, Seung-Kee Min

“…The data included clinical features, angiographic and laboratory findings, treatment modalities, and clinical outcomes. Results : The mean age of the participants was 40.3±20.3 years, with a predominance of female (75.0%). …”
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Improving care experiences for premenstrual symptoms and disorders in the United Kingdom (UK): a mixed-methods approach by E. L. Funnell, N. A. Martin-Key, S. Bahn

“…Results The sample included 339 participants who completed at least 97% of the survey, reported premenstrual symptoms in consecutive cycles, and had sought formal help for these symptoms. Mean age was 34.66 (SD = 5.88), with the majority identifying as women (n = 332, 97.94%) and white/Caucasian (n = 311, 91.74%). 75.22% (n = 255) felt that care was poor. 44.25% (n = 150) felt their symptoms were not taken seriously. 37.76% perceived a lack of healthcare professional knowledge (n = 128). …”
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