qBiCo: a method to assess global DNA conversion performance in epigenetics via single-copy genes and repetitive elements by Faidra Karkala, Roy B. Simons, Floor Claessens, Vivian Kalamara, Manfred Kayser, Athina Vidaki

“…Abstract Background Human DNA methylation profiling offers great promises in various biomedical applications, including ageing, cancer and even forensics. So far, most DNA methylation techniques are based on a chemical process called sodium bisulfite conversion, which specifically converts non-methylated cytosines into uracils. …”
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Risk Estimation of Severe Primary Graft Dysfunction in Heart Transplant Recipients Using a Smartphone by Souhila Ait-Tigrine, Roger Hullin, Elsa Hoti, Matthias Kirsch, Piergiorgio Tozzi

“…Eleven risk factors were identified: female donors, female donor to male recipient, undersized donor, donor age, recipient on ventricular assist device support, recipient on amiodarone treatment, recipient with diabetes and renal dysfunction, re-sternotomy, graft ischemic time, and bypass time. …”
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Architekci pogranicza kulturowego: Julian i Alfred Zachariewiczowie, Iwan Lewiński, Tadeusz Obmiński by Ihor Żuk

“…These four carried out the most important architectural and construction projects of Lviv in the age of the greatest construction boom in the city’s history. …”
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Options of improvement of efficacy of gastroesophageal reflux disease treatment by dioctaedric smectite by O. A. Storonova, A. S. Trukhmanov, N. Yu. Ivashkina, V. T. Ivashkin

“…Overall 45 case records of GERD patients (25 women and 20 men, mean age 43,06 years) were analyzed. All patients underwent esophagogastroduodenoscopy (EGDS) and 24-hour рН-impedance recording prior to the treatment onset and at the 14-th day of therapy. …”
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Clinicopathological Features of 166 Cases of Invasive Ductal Breast Carcinoma and Effect of Primary Tumor Location on Prognosis after Modified Radical Mastectomy by Shiman Chen, Liang Yang, Yaqiong Li

“…There were no significant differences in age, menopause, histological grading, molecular typing, lymph node metastasis, vascular invasion, radiation therapy, and chemotherapy among different groups (P>0.05). …”
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Study of Radioclinical and Risk Factors of Cerebral Venous Thrombosis: A Retrospective Analysis of Patients Presenting to a Tertiary Hospital in Mogadishu, Somalia by Adam BA, Osman AA, Sheikh Hassan M, Sidow NO, Osman Hidig MF, Mohamed AA, Ibrahim AA, Mohamed SA, Mohamed YG, Ahmed SA, Jeele MOO, Hassan MO

“…Descriptive statistics and chi-square tests were used for analysis.Results: The majority of patients were female (86.76%) and aged 20– 40 years (86.76%). Significant risk factors included the postpartum period (77.94%) and pregnancy, with statistical analysis showing strong associations between CVT and the postpartum period (χ² = 62.96, p < 0.0001) and pregnancy (χ² = 5.21, p = 0.022). …”
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Seroprevalence and Associated Risk Factors of Infectious Bovine Rhinotracheitis (IBR) and Animal Owners’ Knowledge, Attitude and Practice (KAP) Towards the Disease in Selected Dist... by Abdisa Mitiku Danu, Abriham Kebede Deresa, Chala Guyassa Dinagde

“…The significant association (p <0.05) was found for breed, age, body condition and herd size but not for district and sex as risk factors. …”
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Classification and Statistical Trend Analysis in Detecting Glaucomatous Visual Field Progression by Cristiana Valente, Elisa D’Alessandro, Michele Iester

“…Twenty Caucasian patients (mean age 73.8 ± 13.43 years) with open-angle glaucoma were recruited in the study. …”
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Interaction effect between overweight/obesity and alcohol consumption on hypertension risk in China: a longitudinal study by Xiaoqin Wang, Zhaozhao Hui, Jiaru Sun, Paul D Terry, Xiaohan Ren, Shuangyan Lei, Caihua Wang, Mingxu Wang

“…A total of 13 121 residents from 12 provinces were included and completed physical examinations and questionnaires at baseline.Outcome First incidence of hypertension.Results Over a mean follow-up of 4 years, 690 incident hypertension cases were reported. After adjusting for age, gender, education level, marital status, physical activity, diabetes and smoking, high body mass index (BMI) and light drinking (OR=5.07, 95% CI 3.06 to 8.41), high waist circumference (WC) and light drinking (OR=4.81, 95% CI 2.92 to 7.91), high waist hip ratio and light drinking (OR=2.85, 95% CI 1.84 to 4.42) were the highest risk of all participants in the three combinations. …”
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ASA Class Is a Stronger Predictor of Early Revision Risk Following Primary Total Knee Arthroplasty than BMI by Christopher J. Wall, MBBS, BMedSc, FRACS, FAOrthA, Richard N. de Steiger, MBBS, PhD, DipBiomech, FRACS, FAOrthA, Christopher J. Vertullo, MBBS, PhD, FRACS, FAOrthA, Dylan Harries, BSc(Hons), MBiostat, PhD, Srinivas Kondalsamy-Chennakesavan, MBBS, MPH, FRSPH

“…A total of 274,786 primary TKAs (54.5% female; mean age, 68.3 years) were included in the study, of which 5,401 were revised during the study period. …”
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The e-STROKE Study: The Design of a Prospective Observational Multicentral Study by Kateřina Dvorníková, Veronika Kunešová, Svatopluk Ostrý, Robert Mikulík, Michal Bar

“…Data collection includes demographic, clinical, and imaging data variables such as age, sex, ethnicity, risk factors, treatment times (OTT, DNT, and OGT), TICI scores, post-treatment hemorrhage (ECAS II), mRS outcome, stroke etiology, e-ASPECTS, acute ischemic volume (AIV), thrombus length on NCCT, CTA collateral score and collateral vessel density, location of large vessel occlusion, ischemic core, hypoperfusion volume, mismatch ratio and volume, final infarct volume, hemorrhage volume, and MRI in case of negative follow-up NCCT. …”
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Characterization of microbiota signatures in Iberian pig strains using machine learning algorithms by Lamiae Azouggagh, Noelia Ibáñez-Escriche, Marina Martínez-Álvaro, Luis Varona, Joaquim Casellas, Sara Negro, Cristina Casto-Rebollo

“…Results Beta diversity analysis on 16 S rRNA microbiome data revealed compositional divergence among genetic, age and batch groups. ML models exploring maternal, paternal and heterosis effects showed varying levels of classification performance, with the paternal effect scenario being the best, achieving a mean Area Under the ROC curve (AUROC) of 0.74 using the Catboost (CB) algorithm. …”
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The Relationship of Attitudes toward Other Religious Groups with Perceived Islamophobia, Intergroup Contact, and Social Identity: A Study among Muslims Living in Western Countries by Kenan Sevinç, Metin Güven

“…., Germany, and other Western countries, aged 18 and 55+. The survey deployed “Social Identification Scale” and “Perceived Islamophobia Scale.” …”
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Colostrum feeding practice and associated factors among mothers who come for postnatal care to Asella referral and teaching hospital, Arsi Zone, South-East Ethiopia by Gisha Haji, Gebi Agero, Amde Eshete, Abdurahman Hasan, Ahmed Hiko

“…The variables with significant association were identified based on p-value &lt; 0.05.ResultsIn this study, 301 study participants took part, with a 99% response rate. The mean age of mothers was found to be 27.13 ± 5.46. This study’s overall prevalence of practice was 57.8% (95% CI, 52.2–63.35). …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…Jianwen Li,1,2,&ast; Hongqi Meng,3,&ast; Wenlai Guo,3 Lubin Zhou,4 Siyu Wu,3 Guanghui Gao,4 Quanzhe Liu,3 Di You,5 Wenrui Qu2,3 1Gastroenteric Medicine and Digestive Endoscopy Center, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Changchun, 130041, People’s Republic of China; 3Department of Hand Surgery, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 4Polymeric and Soft Materials Laboratory, Advanced Institute of Materials Science, School of Chemical Engineering, Changchun University of Technology, Changchun, 130012, People’s Republic of China; 5Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130012, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Di You; Guanghui Gao, Email youdi1118@jlu.edu.cn; ghgao@ccut.edu.cnBackground: Diabetic foot ulcers (DFUs) are often associated with persistent inflammatory response, impaired macrophage polarization, and slow vascular regeneration. …”
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Prognostic Factors for COVID-19 Hospitalized Patients with Preexisting Type 2 Diabetes by Yuanyuan Fu, Ling Hu, Hong-Wei Ren, Yi Zuo, Shaoqiu Chen, Qiu-Shi Zhang, Chen Shao, Yao Ma, Lin Wu, Jun-Jie Hao, Chuan-Zhen Wang, Zhanwei Wang, Richard Yanagihara, Youping Deng

“…Twelve risk factors predictive of mortality were identified. Older age (HR = 1.076, 95% CI = 1.014–1.143, p=0.016), elevated glucose level (HR = 1.153, 95% CI = 1.038–1.28, p=0.0079), increased serum amyloid A (SAA) (HR = 1.007, 95% CI = 1.001–1.014, p=0.022), diabetes treatment with only oral diabetes medication (HR = 0.152, 95%CI = 0.032–0.73, p=0.0036), and oral medication plus insulin (HR = 0.095, 95%CI = 0.019–0.462, p=0.019) were independent prognostic factors. …”
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Conversion from clinically isolated syndrome to multiple sclerosis: what paraclinical tests findings are the most characteristic? by M. Malciūtė, I. Čelpačenko, R. Stankevičiūtė, R. Balnytė

“…The patients were divided into 2 groups according to the final diagnosis (MS group and non-MS group) and into 3 age groups (18-30, 30-50, >50 years old). The prevalence and statistical difference of paraclinical tests were estimated between the groups. …”
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Hispanic Patients Undergoing Spinal Fusion for Neuromuscular Scoliosis Sustain Health Inequalities by Armando S. Martinez, David Momtaz, Travis Kotzur, Alexandra McLennan, Abdullah Ghali, Farhan Ahmad, Ebubechi Adindu, Alan C. Santiago-Rodriquez, Ali Seifi, Brian Smith

“…Results: Compared to non-Hispanic patients (N=1829), Hispanic patients (N=431) had spinal fusion with instrumentation at younger ages (12.9 vs. 14.1 years old, p=0.011) and had significantly different household incomes with less representation in the 75th to 100th percentile (16.8% vs. 26.5%, p<0.001). …”
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Associated factors and prognostic implications of neutropenia in individuals with HIV/AIDS by Pengpeng Li, Xiaoyan Lv, Hui Shen, Jiamin Fang, Mingrui Wei, Xiaoyan Liu, Fuling Zhou

“…Kaplan–Meier survival curve analysis showed that Grade 2 neutropenia group (ANC<0.5 × 109/L) had a worse prognosis than Grade 1 neutropenia group (0.5 × 109/L ≤ ANC<2 × 109/L, p = 0.019) and non-neutropenia group (ANC ≥ 2.0 × 109/L, p = 0.008). Older age (p = 0.002), lower hemoglobin levels (p = 0.001), and a reduced proportion of bone marrow granulocytes (p = 0.002) were associated with a poorer prognosis in PLWHA. …”
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Application of deep learning model based on unenhanced chest CT for opportunistic screening of osteoporosis: a multicenter retrospective cohort study by Chengbin Huang, Dengying Wu, Bingzhang Wang, Chenxuan Hong, Jiasen Hu, Zijian Yan, Jianpeng Chen, Yaping Jin, Yingze Zhang

“…Abstract Introduction A large number of middle-aged and elderly patients have an insufficient understanding of osteoporosis and its harm. …”
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