Arbovirus exposure and subclinical myocardial dysfunction in an Indigenous population in Northeast Brazil: a cross-sectional study by Jandir Mendonça Nicacio, Carlos Dornels Freire de Souza, Ricardo Khouri, Vanessa Cardoso Pereira, Rodrigo Feliciano do Carmo, Pedro Vinícius Amorim de Medeiros Patriota, Sávio Luiz Pereira Nunes, Jeová Cordeiro de Morais Júnior, Manoel Barral-Netto, João Augusto Costa Lima, Anderson da Costa Armstrong

“…Results One hundred seventy-four participants were included, with a median age of 45.0 years (interquartile range 38.0–55.0). …”
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Short-term costs of alcohol-associated hepatitis care in different clinical settings by Chi Mai Nguyen, Jing Su, Yang Li, Ryan Healey, Shihui Jiang, Jiangqiong Li, Naga Chalasani, Samer Gawrieh, Suthat Liangpunsakul, Wanzhu Tu

“…The cohort included individuals aged 21 years and older diagnosed with AH from January 1, 2016, to September 30, 2023. …”
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Prevalence, aetiology, and service mapping of dementia in rural Uganda. Part of DEPEND Uganda (Dementia Epidemiology, unmet Need and co-Developing Solutions in Uganda). [version 2;... by Joseph Mugisha, Nicholas J Ashton, Claire J Steves, Racheal Alinaitwe, Josephine Prynn, Tunde Peto, Beatrice Kimono, Martin Prince

“…Methods The study is nested within the General Population Cohort run by the Medical Research Council/Uganda Virus Research Institute & London School of Hygiene and Tropical Medicine Research Unit. All adults aged 60+ (around 1400) are undergoing brief cognitive screening. …”
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A clinical decision model for failed adrenal vein sampling in primary aldosteronism by Sophie N. M. ter Haar, Sofie J. van Goor, Eleonora P. M. Corssmit, Arian R. van Erkel, Bartholomeus E. P. B. Ballieux, Olaf M. Dekkers, Olaf M. Dekkers, Michiel F. Nijhoff

“…The Youden index calculated cut-off values, targeting a specificity >90% for PA subtype differentiation.ResultsThe cohort, averaging 48.5 ± 9.5 years in age, comprised 21 women and 33 men, among whom 26 presented with unilateral and 28 with bilateral disease. …”
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Retrospective analysis of disease characteristics and treatment patterns among patients with esophageal cancer across 14 surgically represented centers by Zhihao Lu, Mingfei Geng, Yongtao Han, Jianzhong Cao, Jun Wang, Tianshu Liu, Xianglin Yuan, Xue Meng, Yanqiao Zhang, Rong Zhao, Lixin Wan, Enxiao Li, Wenran Wang, Zhijie Li, Danfeng Shi, Jing Qian, Si Shi, Fengshi Dong, Lin Shen

“…Results: Of 3,493 patients, 75.7% were men, the mean age was 64.1 years, and 75.0% had no family history of cancer. …”
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The prognostic significance of tertiary lymphoid structures in oral squamous cell carcinomas: a systematic review by V. Ribeiro, J-L. Teillaud, J-L. Teillaud, J-L. Teillaud, M-C. Dieu-Nosjean, M-C. Dieu-Nosjean, M-C. Dieu-Nosjean, G. Lescaille, G. Lescaille, G. Lescaille, G. Lescaille, G. Lescaille, J. Rochefort, J. Rochefort, J. Rochefort, J. Rochefort, J. Rochefort

“…Remarkably, Tertiary Lymphoid Structures (TLS) identified in solid tumors have shown associations with favorable outcomes, yet their prognostic significance in OSCC remains understudied.ObjectiveThus, this systematic review aims to explore the value of TLS in OSCC reported in the literature.MethodA scoping review was conducted and six retrospective cohort studies involving 1,203 patients met the inclusion criteria.ResultsPredominantly male patients, with an average age of 49.3 years were included. Immunohistochemistry was the primary method to identify TLS, present in 21% up to 100% of cases. …”
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General practitioner-centered rural obesity management: Design, protocol and baseline data of the German HAPpEN pragmatic trial by Marika Haderer, Reiner Hofmann, Tina Bartelmeß, Laura König, Constanze Betz, Mirna Al Masri, Alisa Bader, Natascha von Schau

“…Results: The baseline cohort (mean age: 46.9 ± 11.8 years, 74.1 % female) exhibited high obesity rates (mean BMI: 40.1 ± 6.1 kg/m2), with 48.5 % classified as grade III obese. …”
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Oral health-related quality of life of community-dwellers in the canton of Bern, Switzerland by Roberta Borg-Bartolo, Andrea Roccuzzo, Christian Tennert, Maria Prasinou, Maurus Jäggi, Pedro Molinero-Mourelle, Michael M. Bornstein, Guglielmo Campus

“… Objective: The study aims to describe and analyze the oral health-related quality of life (OHRQoL) of persons aged ≥45 years in the canton of Bern, Switzerland. …”
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Biological and psychosocial factors associated with the persistence of pruritus symptoms: protocol for a prospective, exploratory observational study in Germany (individual project... by Sonja Ständer, Stefan W Schneider, Gudrun Schneider, Stefan Kahnert, Manuel Pedro Pereira, Christian Mess, Volker Huck, Konstantin Agelopoulos, Gina Frank

“…Within 1 year, patients and 80 age-matched and sex-matched healthy controls will be examined at three time points, allowing cross-sectional comparison and a longitudinal investigation of predictive outcome factors in patients under treatment according to existing guidelines.Ethics and dissemination The study has been approved by the ethics committees of Hamburg (2020-10200-BO-ff) and Münster (2020-676 f-S), Germany. …”
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Influence of Cardiorespiratory Fitness on PPARG mRNA Expression Using Monozygotic Twin Case Control by Marcos Roberto Queiroga, Ricardo Augusto Barbieri, Sandra Aires Ferreira, André Ducati Luchessi, Rosario Dominguez Crespo Hirata, Mario Hiroyuki Hirata, Eduardo Kokubun

“…Monozygotic twin pairs aged 11–18 years were grouped into discordant (D) and concordant (C) high and low VO2max groups. …”
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Epidemiology of notifiable outbreaks in different hospital units in Saudi Arabia: A national descriptive study by Nawal M. Alanazi, Nasser H. Alshanbari, Hala M. Roushdy, Yahya I. Alnshbah, Eman Ali Barnawi, Nawaf M. Almatrafi, Rula Felemban, Zainah M. Al Shahrani, Nadeen Burhan, Aiman El-Saed, Khalid H. Alanazi

“…Males represented 62.3 % of the patients, and the average age was 51.2 ± 27.7 years. Almost all patients had devices: central line (63.6 %), foley catheters (52.7 %), or mechanical ventilation (50.4 %). …”
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The Increased Ratio of Blood CD56bright NK to CD56dim NK Is a Distinguishing Feature of Primary Sjögren’s Syndrome by Bingxia Ming, Tong Wu, Shaozhe Cai, Peng Hu, Jungen Tang, Fang Zheng, Cong Ye, Lingli Dong

“…We included 52 pSS patients fulfilling the 2002 AECG criteria or 2012 ACR criteria and 20 age- and gender-matched healthy volunteers. The frequency and absolute number of NK cells and CD56 NK cell subsets in peripheral blood samples were detected by flow cytometry. …”
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The proportion of clinically relevant alarms decreases as patient clinical severity decreases in intensive care units: a pilot study by Ryota Inokuchi, Kent Doi, Kazuaki Shinohara, Kensuke Nakamura, Takehiro Matsubara, Susumu Nakajima, Hajime Sato, Masataka Gunshin, Takahiro Hiruma, Takeshi Ishii, Yoichi Kitsuta, Naoki Yahagi, Yuko Nanjo, Masahiro Echigo, Aoi Tanaka, Mitsuo Umezu

“…Objectives To determine (1) the proportion and number of clinically relevant alarms based on the type of monitoring device; (2) whether patient clinical severity, based on the sequential organ failure assessment (SOFA) score, affects the proportion of clinically relevant alarms and to suggest; (3) methods for reducing clinically irrelevant alarms in an intensive care unit (ICU).Design A prospective, observational clinical study.Setting A medical ICU at the University of Tokyo Hospital in Tokyo, Japan.Participants All patients who were admitted directly to the ICU, aged ≥18 years, and not refused active treatment were registered between January and February 2012.Methods The alarms, alarm settings, alarm messages, waveforms and video recordings were acquired in real time and saved continuously. …”
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Influence of Organ‐Specific Extranodal Involvement on Survival Outcomes in Stage IV Diffuse Large B‐Cell Lymphoma by Tong‐Yoon Kim, Tae‐Jung Kim, Eun Ji Han, Gi June Min, Sung‐Soo Park, Silvia Park, Jae‐Ho Yoon, Sung‐Eun Lee, Byung‐Sik Cho, Ki‐Seong Eom, Yoo‐Jin Kim, Hee‐Je Kim, Seok Lee, Chang‐Ki Min, Jong‐Wook Lee, Youngwoo Jeon, Seok‐Goo Cho

“…Methods We retrospectively reviewed data from 119 patients with DLBCL aged < 60 years who achieved CR after chemo‐immunotherapy between 2008 and 2020. …”
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The Conceptual Domain of Hunting and Its Negative Representation in Love: A Cognitive-Cultural Analysis by Raheleh Gandomkar, Masoomeh Hashemi

“…The results showed that factors such as gender, commitment to cohabitation and the suitability of couples in terms of appearance, economy, age, celibacy and ethical orientation affect metaphorical representations. …”
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Analysis of Foreign Tourists’ Behavioral Patterns and Perceptions in Rural Destinations by Hamdollah Sojasi Gheidari, Zahra Soleymani

“…However, in the digital age, many tourists willingly share their photos online and provide geotags, making it relatively easy to access a representative collection of photographs for a specific destination. …”
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A systematic review and meta-analysis of influencing factors of postoperative wound healing in patients with anal fistula (肛瘘患者术后伤口愈合影响因素系统评价与Meta分析)... by CHEN Qi (陈祺), LIU Zhiping (刘志平), BAI Jianying (白建英), LIU Bo (刘博), FENG Jiangxu (冯江雪)

“…Conclusion Age(≥60 years old), alcohol consumption, diabetes, anal fistula duration > 6 months, complex anal fistula, constipation, poor stool quality, postoperative wound infection, and poor wound drainage were the influencing factors of postoperative wound healing in patients with anal fistula. …”
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Seeking and encountering online information for menstrual health: a qualitative study among adolescent schoolgirls in Gianyar Regency and Denpasar City, Bali, Indonesia by Heather Suttor, Kadek Putri Yamayanti, Ni Luh Eka Purni Astiti, Tungga Dewi, Richard D. Chenhall, Ansariadi Ansariadi, Julie Hennegan

“…We conducted a qualitative study in junior high schools in two districts of Bali, Indonesia. 24 school girls aged 13–15 took part. We wanted to understand how they accessed online information and what they learnt from this about menstruation. …”
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Efficacy and safety of neoadjuvant therapy with tislelizumab plus axitinib for nonmetastatic renal cell carcinoma with inferior vena cava tumor thrombus: a retrospective study by Zhongjie Zhao, Zhengsheng Liu, Kaiyan Zhang, Wei Li, Lijian Zhang, Bingliang Jiang, Bin Chen, Jinchun Xing, Xuegang Wang

“…The main outcomes included objective response rate (ORR), reduction of tumor thrombus size and level, surgical outcomes, and adverse events (AEs). The median age was 66 (range, 50–72) years, and five (71.4%) patients were male. …”
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Habitual alcohol consumption associated with reduced semen quality and changes in reproductive hormones; a cross-sectional study among 1221 young Danish men by Anders Juul, Niels Jørgensen, Niels E Skakkebæk, Shanna H Swan, Tina Kold Jensen, Mads Gottschau, Jens Otto Broby Madsen, Anne-Maria Andersson, Tina Harmer Lassen, Lærke Priskorn

“…Objective Study associations between three measures of alcohol consumption (recent, typical/habitual, binging), semen quality and serum reproductive hormones.Design Cross-sectional population based study.Setting and participants 1221 young Danish men, aged 18–28 years were recruited when they attended a compulsory medical examination to determine their fitness for military service from 2008 to 2012. …”
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