Increasing and maintaining rates of standardized depression screening in youth with childhood-onset systemic lupus erythematosus in a pediatric rheumatology clinic by Emily Datyner, Jodi Dingle, Victoria Newsome, Lisa H. Buckley, Natasha Belsky, Seungweon Park, Manda Mitchell, Brooke Fine, Barron Patterson, T. Brent Graham, Alaina Davis

“…Methods Patients with cSLE 12 years of age or older seen for routine follow-up at our pediatric rheumatology clinic from September 16, 2019, through December 30, 2022, were offered the Patient Health Questionnaire-9 modified for adolescents (PHQ-A) to screen for depressive symptoms. …”
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Nasopharyngeal carriage of Staphylococcus aureus in a rural population, Sierra Leone by Lisa Maria Kleine, Emmanuel Marx Kanu, Tobias Grebe, Desmond Mohamed Sesay, Henning Loismann, Maxwell Sesay, Tom Theiler, Viktoria Rudolf, Alexander Mellmann, Laura C. Kalkman, Martin P. Grobusch, Frieder Schaumburg

“…Results: Of 300 participants (62.7 % females, median age: 16 years), 168 (56 %) were colonized with S. aureus-related complex; six participants carried two different S. aureus genotypes, resulting in a total number of 174 isolates. …”
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Transcervical resection of myoma (TCRM): Part I by Peng-Hui Wang, Szu-Ting Yang, Wen-Hsun Chang, Hung-Hsien Liu, Wen-Ling Lee

“…Uterine fibroids occur frequently in women during the reproductive age, and they are rarely associated with clinical meaning because of their benign characteristics and asymptomatic clinical presentation. …”
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Osteoradionecrosis in osseous free flaps after maxillofacial reconstruction: a single-center experience by Jakob Fenske, Philipp Lampert, Eirini Nikolaidou, Claudius Steffen, Marcus Beck, Norbert Neckel, Susanne Nahles, Max Heiland, Friedrich Mrosk, Steffen Koerdt, Carsten Rendenbach

“…Following case matching, 42 patients (10 females, mean age 61.5 ± 9.1 years) were included in the final analysis. …”
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Pulmonary Densitovolumetry Using Computed Tomography in Patients with Nontuberculous Mycobacteria: Correlation with Pulmonary Function Tests by Patricia Gomes Cytrangulo De Marca, Telma Goldenberg, Fernanda Carvalho Queiroz Mello, Alysson Roncally Silva Carvalho, Alan Ranieri Medeiros Guimarães, Roberto Mogami, Agnaldo José Lopes

“…This is a cross-sectional study in which 31 patients with NTM-PD and 27 controls matched by sex, age, and body mass index underwent CT pulmonary densitovolumetry and pulmonary function tests including spirometry and body plethysmograph. …”
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Mineralogy as a potential driver of irregular radiocarbon patterns among Icelandic fluvial carbon pools by Nora Gallarotti, Lisa Bröder, Julie Lattaud, Stephan Wartenweiler, Negar Haghipour, Timothy I Eglinton

“…After excluding other potential factors, we argue that this apparent age inversion among carbon pools in Icelandic rivers may reflect retention of DOC prior to its release to the aquatic continuum through interactions with high surface area minerals prevalent in the volcanic soils of Iceland. …”
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Real-world clinical outcome of unresectable locally advanced & de-novo metastatic pancreatic ductal adenocarcinoma: a multicentre retrospective study by Mohamed Aseafan, Ali H. Alfakeeh, Emad Tashkandi, Mervat Mahrous, Mohammed Alghamdi, Bader Alshamsan, Marwan Al-Hajeili, Safwan Bakhsh, Kanan Alshammari, Fahad A. Almugbel, Abdulhameed H. Alfagih, Ahmed Allehebi, Mohamed Montaser, Mohamed Hamdy Elsafty, Khaled Abd Elaziz Elnaghi, Ibrahim Issa, Eesa Bakshi, Sadeem AlSubaie, Bandar AlMutairi, Hoda Mokhtar, Mohamed Aboelatta, Nedal Bukhari, Ali M. Alzahrani, Tusneem Elhassan, Ali Alqahtani, Shouki Bazarbashi

“…Data were collected from 10 oncology centers across Saudi Arabia. Results The median age at diagnosis was 60 years, with 63% of patients presenting with multiple metastatic sites, primarily in the liver (66.3%). …”
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Self-Perceived Barriers to Pediatric Cancer Care in Sub-Saharan Africa: A Cross-Sectional Multinational Study by Ole Stoeter, Nikolaus C.S. Mezger, Tamara Koenig, Eric Chokunonga, Girum Tessema, Adugna Fekadu Damise, Alda Stevy Makouanzi, Esther Majaliwa, Mahine Ivanga, Bakarou Kamate, Franck Gnahatin, Sarah Nambooze, Ima-Obong A. Ekanem, Toralf Bernig, Biying Liu, Sumit Gupta, Eva Johanna Kantelhardt

“…Inclusion criteria comprised a cancer diagnosis according to the International Classification of Childhood Cancer, age 0-19 years, and year of diagnosis 2017-2019. …”
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Proteinuria and the risk of Incident atrial fibrillation according to glycemic stages: a nationwide population-based cohort study by Muhan Yeo, So-Ryoung Lee, Eue-Keun Choi, JungMin Choi, Kyung-Yeon Lee, Soonil Kwon, Hyo-Jeong Ahn, Bong-Seong Kim, Kyung-Do Han, Seil Oh, Gregory Y. H. Lip

“…Results Overall, the cohort (mean age 47 ± 14 years, 44.8% female) showed increasing annual AF incidence rates from 2.05 to 7.22 per 1000 person-years from normal to late DM (p < 0.001). …”
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Effect of propofol and ciprofol in patients undergoing bronchoscopy: protocol for a double-blind, randomised controlled trial by Fang Chen, Cheng Li, Dongliang Li, Jinxuan Tang, Jiayu Huang

“…This study aims to compare the impact of equivalent effective doses of propofol and ciprofol on haemodynamic changes in patients undergoing bronchoscopy under general anaesthesia.Methods This prospective, double-blind, randomised, controlled clinical trial will recruit 250 patients aged 18–80 years scheduled for elective bronchoscopy under general anaesthesia. …”
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Challenges and barriers to physician decision-making for prescribing and deprescribing among patients with multimorbidity in eastern China’s primary care settings: a qualitative st... by Ming Yan, Zhijie Xu, Andrew Farmer, Yu Xia, Mi Yao, Lingyan Wu, Xinmei Zhou, Liyan Han

“…Themes were developed using a conventional content analysis approach.Setting 12 community health centers and 8 township health centers across four regions in eastern China were included.Participants 26 PCPs from 20 primary care institutions in eastern China were interviewed through purposive sampling, representing a mix of urban and rural healthcare settings.Results Of the 26 participants in this study, 14 (53.8%) were women, and the mean age was 36.3 years old. When prescribing and stopping medications for patients with multimorbidity, they often encounter complex challenges. …”
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Hidden blood loss and risk factors after percutaneous endoscopic transforaminal lumbar interbody fusion by Meng Ge, Meng Ge, Fangbing Zhu, Fangbing Zhu, Weibin Du, Weibin Du, Zhengcong Ye, Zhengcong Ye, Zhenfei Xiong, Zhenfei Xiong, Lukai Zhang, Lukai Zhang, Hua Zhou, Hua Zhou, Jun Yang, Jun Yang

“…PurposeIn this study, we aimed to assess the occurrence of hidden blood loss (HBL) and its associated risk factors in patients with lumbar degenerative diseases who underwent percutaneous endoscopic transforaminal lumbar interbody fusion (Endo-TLIF).MethodsSex, age, height, weight, body mass index, and medical history including hypertension, diabetes, and osteoporosis were recorded. …”
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TOURISM study (Treatment Outcomes in UteRIne SarcoMa): a 10-year retrospective evaluation of practice in the UK by Rebekah Webb, Mohammed Al-Zubaidi, Mark A Baxter, Karin Purshouse, James Robertson, Helen Creedon, Katherine Fair, Asma Sarwar, Laura Hannington, Adam L Peters, Samuel Mcinerney, Karen E Mactier, Georgina E Wood, Mai K Bishr, Leonie Eastlake, Katharine Lankester, Alison L Stillie

“…Routine clinical data, including general patient demographics, diagnosis, treatment and outcomes, were collated and pseudonymised.Setting Patients diagnosed with uterine sarcoma in the UK National Health Service between 1 January 2008 and 31 December 2017 were identified from electronic records.Participants A total of 406 patients from eight centres were eligible for inclusion.Results The median age at diagnosis was 56 years, with leiomyosarcoma the most common diagnosis (54.4%). …”
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Overcoming barriers to engagement and adherence to a home-based physical activity intervention for patients with heart failure: a qualitative focus group study by Guy A MacGowan, Sarah Charman, Djordje G Jakovljevic, Nduka C Okwose, Nicola O'Brien, Sophie Cassidy, David Brodie, Kristian Bailey, Leah Avery

“…Data were analysed using thematic analysis.Participants A purposive sample of 16 patients, 82% male, aged 68±7 years, with heart failure duration of 10±9 years were recruited.Intervention A 12-week behavioural intervention targeting physical activity was delivered once per week by telephone.Results Ten main themes were generated that provided a comprehensive overview of the active ingredients of the intervention in terms of engagement and adherence. …”
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Joint association of sleep patterns and oxidative balance score with all-cause and cardiovascular mortality among the general population by Chen Chen, Hanzhang Wu, Hanzhang Wu, Hongyu Jin, Zhiping Jiang, Wei Wang, Xiao Tan, Xiao Tan, Wen-Yang Li

“…BackgroundThis study investigates the joint effect of sleep patterns and oxidative balance score (OBS) on all-cause and CVD mortality in the general population.MethodsWe examined 21,427 individuals aged 18–85 from NHANES 2005–2014, connecting them to mortality data until December 31, 2019, using interview and physical examination dates. …”
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Efficacy and Safety of an Aflibercept Treat-and-Extend Regimen in Treatment-Naïve Patients with Macular Oedema Secondary to Central Retinal Vein Occlusion (CRVO): A Prospective 12-... by Jose Garcia-Arumi, Francisco Gómez-Ulla, Navea Amparo, Enrique Cervera, Alex Fonollosa, Luis Arias, Javier Araiz, Juan Donate, Marta Suárez de Figueroa, Lucia Manzanas, Jaume Crespí, Roberto Gallego

“…Results. 24 eyes (24 patients) were included; mean (SD) age: 62.8 (15.0) years; 54.2% male; median (IQR) time since diagnosis: 7.6 (3.0, 15.2) days. …”
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Salivary alpha-amylase activity and its association with early childhood caries and rampant caries experience: a cross-sectional study by Vivek Padmanabhan, Md Sofiqul Islam, Muhammed Mustahsen Rahman, Manjunatha B. K. Goud, Latifa Majed Sulaiman Allay Alshehhi, Hebah Mushref Ahmad Hamed, Sheela Haridas, Dileep Sharma

“…It also examines the relationship between salivary alpha-amylase levels and increased caries activity in the children with ECC or RC.Materials and methodsA cross-sectional study was conducted at RAK College of Dental Sciences (RAKCODS) with 100 children aged 3–12 years. Participants were divided into ECC and RC groups, each consisting of study and control groups. …”
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<i>MTHFR</i> Gene Polymorphisms and Cancer Risk in Children and Adolescents: A Systematic Review and Meta-Analysis by Savvas Kolanis, Eleni P. Kotanidou, Vasiliki Rengina Tsinopoulou, Elisavet Georgiou, Emmanuel Hatzipantelis, Liana Fidani, Assimina Galli-Tsinopoulou

“…<b>Background/Objectives:</b> <i>MTHFR</i> gene polymorphisms (677C>T and 1298A>C) correlate with various types of cancer across all age groups; however, a small number of studies have included solely children and adolescents. …”
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The prevalence and burden of musculoskeletal disorders amongst Indigenous people in Pimicikamak, northern Manitoba, Canada: A community health survey by André Bussières, Melissa Atkinson-Graham, Jennifer Ward, Muriel Scott, Jean Moss, Patricia Tavares, Deborah Kopansky-Giles, Jacqueline Ladwig, Cheryl Glazebrook, David A. Monias, Helga Hamilton, Donald Z. Mckay, Randall Smolinski, Scott Haldeman, Sheilah Hogg-Johnson, Steven Passmore

“…Results: The survey was completed by 130 adults (65 % females, mean age, 48.4 years). Nearly all participants (89.6 %) reported having spine symptoms in the past four weeks, with a majority experiencing activity limitations lasting one day or more due to neck (77.9 %) or low back pain (55.6 %). …”
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Effects of high-intensity interval and moderate-intensity continuous training on ambulatory blood pressure and cardiovascular outcomes in older adults with hypertension (HEXA Study... by Francisco Dalton-Alves, Maria Beatriz F Araújo, Bruno Erick B Lucena, Gabriel C Souto, Daniele Samara D Lopes, Maria Isabel S Lucena, Raíssa de Melo Silva, Ludmila L P Cabral, Yuri A Freire, Fabíola L Golveia, Telma Maria Araújo Lemos, Rodrigo A V Browne, Eduardo Caldas Costa

“…The trial is conducted with blinded outcome assessors and statistical analysts. 66 inactive older adults with hypertension aged 60–80 years without a history of major adverse cardiovascular events will be randomly assigned to one of the following groups: (1) HIIT (3 months; 3× week); (2) MICT (3 months; 3× week); (3) health education programme (control; 3 months; 1× week). …”
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