Atypical Antiglomerular Basement Membrane Disease in a Pregnant Patient with Systemic Lupus Erythematosus by Areerat Ounhasuttiyanon, Ngoentra Tantranont, Thatsaphan Srithongkul

“…A review of the literature showed that the atypical anti-GBM is less aggressive than the typical anti-GBM disease. However, several patients had persistent renal dysfunction and 20–30% of patients had progression to ERSD. …”
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Aesthetic dentistry and ethics: a systematic review of marketing practices and overtreatment in cosmetic dental procedures by Masoumeh Rostamzadeh, Farshad Rahimi

“…The commodification of dental care, fueled by aggressive marketing strategies, has resulted in a notable increase in overtreatment, where unnecessary procedures are performed to satisfy commercial pressures and idealized beauty standards. …”
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Primary Gliosarcoma of the Cerebellum in a Young Pregnant Woman: Management Challenges and Immunohistochemical Features by Marco Meloni, Salvatore Serra, Giulia Bellisano, Nikolaos Syrmos, Sanjeeva Jeyaretna, Mario Ganau

“…To this regard, sarcomas, solitary fibrous tumors, and even metastases should be considered, especially in light of the tendency of GS to give rise to extracranial localizations. Whenever an aggressive management with radical excision and adjuvant treatment is not safely achievable, disease progression is likely to be unavoidable.…”
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Investigation of survival and prognostic factors in triple negative molecular subtype male breast cancer patients: A population-based study by Ahmet Necati Sanli, Bilal Turan

“…It is encouraging that triple negative molecular subtype breast cancer, which is an aggressive tumor, is less common in men. [Med-Science 2024; 13(4.000): 829-34]…”
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A unique case of extranodal marginal zone lymphoma with synchronous pulmonary and dermatologic manifestations by Carlo Arevalo, Fernando Camacho, Joseph Modrak

“…Initial work-up was remarkable for normocytic anemia, lymphopenia, mild hypercalcemia, and elevated inflammatory markers. Despite aggressive diuresis, his respiratory distress worsened requiring up-titration of supplemental oxygen (6–8L/min). …”
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A computational and structural approach to identify malignant non-synonymous FOXM1 single nucleotide polymorphisms in triple-negative breast cancer by Prarthana Chatterjee, Satarupa Banerjee

“…Intriguingly, FOXM1 overexpression was found to be highest in Triple-negative breast cancer (TNBC), the most aggressive BC with the worst prognosis. However, FOXM1-mediated TNBC pathogenesis is not completely elucidated. …”
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Screening of cucumber varieties and hybrids for selection of downy mildew resistance sources by N. T. Amirkhanova, A. S. Rsaliyev

“…High variability of the fungus leading to the emergence of new aggressive pathotypes and consequently to loss of resistance by some crop cultivars causes ever-growing harmfulness of P. cubensis. …”
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Vitamin D Receptor, Retinoid X Receptor, Ki-67, Survivin, and Ezrin Expression in Canine Osteosarcoma by John Davies, Heather Heeb, Rama Garimella, Kimberly Templeton, David Pinson, Ossama Tawfik

“…Canine osteosarcoma (OS) is an aggressive malignant bone tumor. Prognosis is primarily determined by clinical parameters. …”
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Balloon Cell Urethral Melanoma: Differential Diagnosis and Management by M. McComiskey, C. Iavazzo, M. Datta, R. Slade, B. Winter-Roach, G. Lambe, V. K. Sangar, M. Smith

“…Adjuvant treatment including chemotherapy, radiotherapy, or immunotherapy has also been reported. Even with aggressive management, malignant melanoma of the urogenital tract generally has a poor prognosis. …”
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RNA-binding protein DAZAP1 accelerates the advancement of pancreatic cancer by inhibiting ferroptosis by Xinqing Wang, Hao Fan, Xiaoping Ye, Yu Hu, Yan Xiao, Ming Zhang, Yonghui Xu, Jianjun Song, Yongyun Luo

“…Abstract Background Pancreatic cancer (PC) is a highly aggressive malignancy with a poor prognosis due to its late-stage diagnosis and limited treatment options. …”
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YPEL2 regulates the efficacy of BRD4-EZH2 dual targeting in EZH2Y641mut germinal center-derived lymphoma by Aránzazu Chamorro-Jorganes, Núria Profitós-Pelejà, Clara Recasens-Zorzo, Juan G Valero, Diana Reyes-Garau, Laura Magnano, Ray Butler, Antonio Postigo, Patricia Pérez-Galán, Marcelo Lima Ribeiro, Gaël Roué

“…Altogether, our results provide first pre-clinical evidence that simultaneous targeting of MYC and EZH2 is a safe and efficient approach that can be monitored by specific biomarkers, in aggressive lymphoid tumors of germinal center origin.…”
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Targeting fucosyltransferase FUT8 as a prospective therapeutic approach for DLBCL by Hao Xu, Qi Li, Yuchen Zhang, Chuan He, Xinyun Zhang, Zhiming Wang, Meifang Zhao, Yali Chai, Wenzhuo Zhuang, Bingzong Li

“…Abstract Diffuse large B-cell lymphoma (DLBCL) is characterized by its aggressive nature and resistance to standard chemotherapy, necessitating the development of new therapeutic approaches. …”
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Combined Klippel-Feil syndrome, Sprengel deformity, and diffuse large B-cell lymphoma: A rare case report by Golnaz Lotfian, MD, Amirmasoud Negarestani, MD, Sarah Gondek, BS, Aleksandr Raskind, DO, William Chen, MD, Emad Allam, MD

“…In particular, awareness of the potential co-existence of congenital abnormalities and aggressive malignancies is critical in such cases.…”
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Thyroid-Specific Genes Expression Uncovered Age-Related Differences in Pediatric Thyroid Carcinomas by Maria Isabel Cunha Vieira Cordioli, Lais Moraes, Maria Teresa de Seixas Alves, Rosana Delcelo, Osmar Monte, Carlos Alberto Longui, Adriano Namo Cury, Janete Maria Cerutti

“…Children (<10 years old) usually present a more aggressive disease than adolescents (≥10–18 years old). …”
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Influence of Duodenal–Jejunal Implantation on Glucose Dynamics: A Pilot Study Using Different Nonlinear Methods by David Cuesta-Frau, Daniel Novák, Vacláv Burda, Daniel Abasolo, Tricia Adjei, Manuel Varela, Borja Vargas, Milos Mraz, Petra Kavalkova, Marek Benes, Martin Haluzik

“…Duodenal–jejunal bypass liner (DJBL) is a reversible implant that mimics the effects of more aggressive surgical procedures, such as gastric bypass, to induce weight loss. …”
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Current biomarkers of prostate cancer by I. A. Aboian, E. N. Fedotova, A. N. Shevchenko, S. M. Pakus, A. Yu. Maximov, E. V. Filatova, I. A. Khomutenko, Е. F. Komarova, N. K. Guskova

“…For example, biomarkers such as %-free PSA, Prostate Health Index (PHI) or 4K score can be used to increase specificity and reduce the number of unnecessary biopsies, while the PCA3 test can be used to reduce the number of repeated biopsies in men with previously negative biopsy. To determine aggressiveness and predict the outcome of the disease, tissue multigenic tests can be used, such as: T2-ERG, ExoDx, SelectMDx and ConfirmMDx, Prolaris, Oncoytype DX, Decipher. …”
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Giant Protruding Nodular Fasciitis of the Anterior Chest Wall Clinically Mimicking a Soft Tissue Sarcoma by Hideyuki Kinoshita, Tsukasa Yonemoto, Hiroto Kamoda, Yoko Hagiwara, Toshinori Tsukanishi, Sumihisa Orita, Kazuhide Inage, Naoya Hirosawa, Seiji Ohtori, Takeshi Ishii

“…Owing to its rapidly growing nature, a precise clinical diagnosis is difficult; it is frequently misdiagnosed as an aggressive or malignant tumor. Herein, we present the case of a 15-year-old male who presented with a large protruding mass on the anterior chest wall. …”
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Obtaining a pancreatic cancer cell line stably expressing doxycycline-dependent endonuclease Cas9 by A.K. Nurgalieva, V.S. Skripova, L.F. Minigulova, R.G. Kiyamova

“…Pancreatic cancer is one of the most painful and aggressive types of cancer with high lethality rate. …”
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Younger Age Is Associated with Poorer Survival in Patients with Signet-Ring Cell Carcinoma of the Colon without Distant Metastasis by Ben Huang, Mengdong Ni, Chen Chen, Yang Feng, Sanjun Cai

“…In this study, we aim to analyze the impact of age on cancer-specific survival (CSS) in patients with signet-ring cell carcinoma (SRCC) of the colon, a particularly aggressive type of colon cancer. Methods. Information on patients with SRCC of the colon with no distant metastasis was extracted from the US Surveillance, Epidemiology, and End Results (SEER) database. …”
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Calcium carbonate sediment corrosion and formation investigation in drinking water distribution network in Sough City, Iran by Abdol Hosein Salehi Sarvak, Seyed Ali Almodaresi, Abolghasem Mirhosseini Deh-abadi, Masoud Reza Shishehbore, Abdol Hosein Kangazian, Ali Akbar Jamali

“…The parameters included pH, TDS, water temperature, total alkalinity, calcium hardness, and total hardness indices of Langelier, Ryznar, Pokurious, and Aggressive were measured in all sources. The mean indices were -0.59 ± 0.62, 8.48 ± 0.79, 7.24 ± 0.28, and 12.01 ± 0.22, respectively. …”
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