Modified Kraske Procedure with Mid-Sacrectomy and Coccygectomy for En Bloc Excision of Sacral Giant Cell Tumors by Vítor M. Gonçalves, Álvaro Lima, João Gíria, Nuno Carvalho, José Parreira, Manuel Cunha e Sá

“…Sacral giant cell tumors are rare neoplasms, histologically benign but potentially very aggressive due to the difficulty in achieving a complete resection, their high recurrence rate, and metastization capability. …”
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NFE2-driven neutrophil polarization promotes pancreatic cancer liver metastasis progression by Wenchao Xu, Jianzhou Liu, Qiaofei Liu, Jia Xu, Li Zhou, Zhiyong Liang, Haoran Huang, Bowen Huang, Gary Guishan Xiao, Junchao Guo

“…Here, combined single-cell sequencing with spatial transcriptomics results revealed that liver metastases exhibit more aggressive transcriptional characteristics and higher levels of immunosuppression compared with the primary tumor. …”
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Genetic and epigenetic characterization of sarcoma stem cells across subtypes identifies EZH2 as a therapeutic target by Edmond O’Donnell, Maria Muñoz, Ryan Davis, Jessica Bergonio, R. Lor Randall, Clifford Tepper, Janai Carr-Ascher

“…Abstract High-grade soft tissue sarcomas (STS) are a heterogeneous and aggressive set of cancers. Failure to respond anthracycline chemotherapy, standard first-line treatment, is associated with poor outcomes. …”
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Plasmacytoid Urothelial Carcinoma of the Bladder Metastatic to the Stomach: A Case Report by Philippe Nabbout, James Furr, Murugan Paari, Gennady Slobodov

“…Plasmacytoid urothelial carcinoma of the bladder is an aggressive variant of urothelial carcinoma. Based on our case and the literature review, this tumor can be misdiagnosed because of its rarity, leading to treatment delays. …”
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Stratifying vascular disease patients into homogeneous subgroups using machine learning and FLAIR MRI biomarkers by Karissa Chan, Corinne Fischer, Pejman Jabehdar Maralani, Sandra E. Black, Alan R. Moody, April Khademi

“…Based on biomarker and clinical profiles, Subgroup 4 was characterized with neurodegeneration unrelated to CVD, Subgroup 3 identified patients with high CVD risk requiring aggressive intervention, and Subgroups 1, 2, and 5 identified patients with varying levels of moderate risk, suitable for long-term lifestyle interventions. …”
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Evaluation of Yield, Yield Component and Usefulness Indices of Bean (Phaseolus vulgaris) and Maize (Zea mays) Intercropping under Inoculation with Rhizobium phaseoli by Ebrahim Zolfagari Kotbehsara, Peyman Sharifi, Mohammad Hossein Ansari

“…This shift indicates that maize had a lower competitive ability compared to beans in inoculated conditions within the mixed cropping system.  The Aggressivity index for beans was positive under inoculated conditions across all three intercropping ratios, further supporting its competitive advantage. …”
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Southern Pine Beetle, Dendroctonus frontalis Zimmermann (Insecta: Coleoptera: Scolytidae) by James R. Meeker, Wayne N. Dixon, John L. Foltz, Thomas R. Fasulo

“…A recent historical review estimated that SPB caused $900 million of damage to pine forests from 1960 through 1990 (Price et a1. 1992). This aggressive tree killer is a native insect that lives predominantly in the inner bark of pine trees. …”
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Agonistic Behaviors of The Anemonefish Amphiprion ocellaris Living with Their Host Anemones by Lempereur Antoine, Nguyen Hai-Thanh Thi

“…Agonistic behaviours, defined as an individual’s aggressive behavior towards a conspecific, facilitate a social ranking throughout the animal kingdom, particularly within anemonefish group. …”
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Exploring novel immunotherapy biomarker candidates induced by cancer deformation. by Se Min Kim, Namu Park, Hye Bin Park, JuKyung Lee, Changho Chun, Kyung Hoon Kim, Jong Seob Choi, Hyung Jin Kim, Sekyu Choi, Jung Hyun Lee

“…Triple-negative breast cancer (TNBC) demands urgent attention for the development of effective treatment strategies due to its aggressiveness and limited therapeutic options [1]. This research is primarily focused on identifying new biomarkers vital for immunotherapy, with the aim of developing tailored treatments specifically for TNBC, such as those targeting the PD-1/PD-L1 pathway. …”
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Man against machine: Debates in the expert community on the lethal autonomous systems by A. Yu. Lipova

“…Both the Russian and the Western experts agree that the contemporary international humanitarian law is unable to handle the challenges posed by aggressive development of the lethal autonomous weapons. …”
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Gambling in Connecticut adolescents: Prevalence, socio-demographic characteristics, trauma exposure, suicidality, and other risk behaviors. by Elina A Stefanovics, Zu Wei Zhai, Marc N Potenza

“…Gambling was further associated with suicidality and risk behaviors including substance use, smoking [traditional tobacco and electronic vapor use], risky use of digital technologies, unsafe sex, and aggressive behaviors. Gambling was also associated with traumatic experiences, depression/dysphoria, poor academic performance, and less familial social support. …”
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Early Recurrence of Ovarian Cancer during Pregnancy after Primary Staging Surgery in the First Trimester by Munetoshi Akazawa, Kazunori Hashimoto

“…Even in the case of nonadvanced cancer, it has the potential to be an extremely aggressive malignancy under the irregular hormonal environment of pregnancy.…”
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Immediate Surgery Might Be a Better Option for Subcapsular Thyroid Microcarcinomas by Jun Jiang, Hui Lu

“…This study aimed to evaluate the location of PTMCs in the thyroid lobe and determine whether location is associated with an aggressive biology and the necessity of immediate surgery. …”
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Iran-Saudi Arabia Rivalry and the Yemen Crisis by Ramazan İZOL

“…On the other hand, with the aggressive policy of Saudi Arabia towards them, the Houthis have further developed their relations with Iran for pragmatic and ideological reasons. …”
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An Innovative School Design Based on a Biophilic Approach Using the Appreciative Inquiry Model: Case Study Scandinavia by Amjad Almusaed, Asaad Almssad, Karim Najar

“…To understand the school’s role in society and its works, it became essential to reevaluate its functions and importance for society after the aggressive attack of the COVID-19 pandemic. Thus, a new educational space design represents a powerful and required tool for stimulating creativity and increasing concentration, motivation, and assimilation of knowledge for future generations. …”
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Study on the Stress Relaxation Behavior of Large Diameter B-GFRP Bars Using FBG Sensing Technology by Li Guo-wei, Pei Hua-Fu, Hong Cheng-yu

“…Corrosion of steel tendons in certain aggressive environments could lead to durability problems of civil engineering. …”
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The Breaking of the Square: Late Victorian Representations of Anglo-Sudanese Warfare by Luisa Villa

“…The analysis elicits reflections on the construction of normative masculinity (with its emphasis on disciplined aggressiveness), on the perception of modern technology (which often made victory over native fighters alarmingly easy and hardly honorable), on the “uses” of violence and on the dynamics of “Imperialist nostalgia” (as the anthropologist Rosaldo dubbed it), i.e. the coloniser’s own regret at the inevitable destruction of native societies brought about by the process of compulsory modernization.…”
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POLITIK ISLAM MAHATHIR MOHAMMAD DI MALAYSIA DAN SOEHARTO DI INDONESIA by M. Zaki Mubarak, Mohamad Zaini Abu Baka

“…On the contrary, the Mahathir regime has successfully survived in facing the similar crisis, so that his pro-Islamic policy has passed off although not as aggressive as in the past.…”
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Monitoring Disease Progression and Therapeutic Response in a Disseminated Tumor Model for Non-Hodgkin Lymphoma by Bioluminescence Imaging by Margarethe Köberle, Kristin Müller, Manja Kamprad, Friedemann Horn, Markus Scholz

“…Our aim was to establish and apply a model for aggressive CD20-positive B-cell non-Hodgkin lymphomas, enabling us to monitor tumor growth and shrinkage in a noninvasive manner. …”
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Minimizing Harmonic Distortion Impact at Distribution System with Considering Large-Scale EV Load Behaviour Using Modified Lightning Search Algorithm and Pareto-Fuzzy Approach by S. N. Syed Nasir, J. J. Jamian, M. W. Mustafa

“…Therefore, it can be concluded that the MLSA is suitable method to mitigate harmonic and it is beneficial in minimizing the impact of aggressive CS installation at distribution network.…”
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