Polymicrobial Bacteremia Involving Comamonas testosteroni by Jose Orsini, Eric Tam, Naomi Hauser, Salil Rajayer

“…In spite of its uncommon human pathogenesis, there are few reports on the aggressive manner of it as an opportunistic pathogen, mostly related to testosteroni spp. …”
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Recurrence of Primary Vascular Leiomyosarcoma Five Years after Initial Diagnosis in the Lower Extremity by Hilal Erinanc, Mehmet Ozulku, Aysen Terzi

“…Although it is an extremely aggressive tumor, the symptoms may be unspecific, especially in the lower extremities. …”
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The Janus Face of Lipids in Human Breast Cancer: How Polyunsaturated Fatty Acids Affect Tumor Cell Hallmarks by Benoît Chénais, Vincent Blanckaert

“…While most of the results obtained with docosahexaenoic acid and/or eicosapentaenoic acid show a decrease of tumor cell proliferation and/or aggressivity, there is some evidence that other lipids, which accumulate in breast cancer tissues, such as arachidonic acid may have opposite effects. …”
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Mixed Fungal Infection (Aspergillus, Mucor, and Candida) of Severe Hand Injury by Milana Obradovic-Tomasev, Aleksandra Popovic, Nada Vuckovic, Mladen Jovanovic

“…After ten weeks the patient was successfully cured. The aggressive nature of Mucor and Aspergillus skin infection was described. …”
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Hepatic Arterial Embolization for the Treatment of Metastatic Neuroendocrine Tumors by Eric Lee, H. Leon Pachter, Umut Sarpel

“…Long-term survival is not uncommon, making aggressive palliation of symptoms an important component of treatment.…”
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Acute Warfarin Toxicity as Initial Manifestation of Metastatic Liver Disease by Varalaxmi Bhavani Nannaka, Nihar Jani, Masooma Niazi, Dmitry Lvovsky

“…She rapidly deteriorated with acute respiratory failure requiring mechanical ventilation, profound shock requiring high dose vasopressor infusion, severe coagulopathy, worsening liver enzymes with worsening of lactic acidosis and severe metabolic abnormalities, and refractory to aggressive supportive care and died in less than 48 hours. …”
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Adult Intramedullary Ewing Sarcoma of the Proximal Hip by Preetam Gongidi, Siva Jasti, William Rafferty, Veniamin Barshay, Richard Lackman

“…The permeative nature of the lesion can elicit new bone formation creating a partially sclerotic appearance, cortical expansion presenting as a “Codman triangle,” or have an “onion-skin” type of aggressive periosteal reaction/periostitis. Ewing sarcoma is rarely seen without an associated soft-tissue mass and is even rarer to just have benign-appearing periostitis (e.g., thick, uniform, or wavy cortex). …”
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Bile acids and incretins as modulators of obesity-associated atherosclerosis by Andrijana Kirsch, Juergen Gindlhuber, Diana Zabini, Elena Osto, Elena Osto

“…Obesity is one of the major global health concerns of the 21st century, associated with many comorbidities such as type 2 diabetes mellitus (T2DM), metabolic dysfunction-associated steatotic liver disease, and early and aggressive atherosclerotic cardiovascular disease, which is the leading cause of death worldwide. …”
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The rhabdoid variant of adrenocortical carcinoma-Report of three cases and literature review by Pavithra Ayyanar, Mukund N. Sable, Amit K. Adhya, Manoj K. Das, Madhabananda Kar, Pritinanda Mishra

“…Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy. Extensive rhabdoid morphology in ACC has been described recently in very few cases. …”
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Sealing Compositions Based on Polysulfide Oligomers Obtained by a Modified Method by Z.K. Myshyrova, M.I. Tulepov, L.R. Sassykova, R. Busquets

“…The work also assessed the resistance of composites to the action of aggressive substances after exposure of composites in various media (gasoline, benzene, concentrated acids), it was noted that the introduction of MWCNT increases this indicator. …”
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New developments in immunotherapy for SCLC by Zhonglin Hao, Tsering Dolkar, Christopher Gates, Reinhold Munker

“…Small cell lung cancer (SCLC) is an aggressive form of neuroendocrine neoplasm known for its striking initial response to treatment, followed by fast relapse and refractoriness in response to additional lines of therapy. …”
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Papillary Endolymphatic Sac Tumor: A Case Report by S. Arava, R. M. Soumya, S. Chitragar, R. Safaya, S. H. Chandrashekhar, Alok Thakar

“…A distinct subclass of these tumors demonstrates microscopic papillary architecture and has a propensity to erode the petrous bone and extend intracranially. The term “aggressive papillary middle ear tumor” has recently been proposed to describe this more invasive type of middle ear tumor. …”
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Eight-Year Follow-Up Using a Fresh Osteochondral Allograft for a Femoral Head Chondroblastoma in a 17-Year-Old Patient by Louis-Charles Moreau, Philippe Beauchamp-Chalifour, Etienne L. Belzile, Norbert Dion

“…Chondroblastoma located in the femoral head is associated with a higher recurrence rate and carries the additional risks of head collapse and degenerative hip disease. Aggressive curettage followed by bone grafting is the current mainstay of treatment. …”
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Surveillance for the Management of Small Renal Masses by Mehmet Ozsoy, Tobias Klatte, Matthias Waldert, Mesut Remzi

“…Imaging alone is inadequate for suggesting the aggressive potential of SRM for both diagnosis and followup. …”
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Brief Report: Clinical Characteristics and Outcomes of Patients With Thoracic SMARCA4-Deficient Undifferentiated Tumors by Alissa J. Cooper, MD, Andrea Arfe, PhD, Biagio Ricciuti, MD, Andréanne Gagné, MD, PhD, Lynette M. Sholl, MD, Alessandro Di Federico, MD, Mark M. Awad, MD, PhD, Mihaela Aldea, MD, PhD, Maria Rosa Ghigna, MD, Miruna Grecea, MD, Phoebe Clark, MS, Jamie E. Chaft, MD, Mark G. Kris, MD, Gregory J. Riely, MD, Charles M. Rudin, MD, PhD, Ibiayi Dagogo-Jack, MD, Mari Mino-Kenudson, MD, Lingzhi Hong, MD, PhD, Neda Kalhor, MD, Natalie Vokes, MD, Anita Bowman, MS, Soo-Ryum Yang, MD, Natasha Rekhtman, MD, PhD, Adam J. Schoenfeld, MD

“…Introduction: Thoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UTs) are a recently defined group of aggressive cancers in which the effectiveness of standard treatments for lung cancer is unknown. …”
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Phthalate exposure induces microRNA-5010/Nrf2-EGR1/GDF15 signaling expression in prostate cancer by Yuh-Shyan Tsai, Yeong-Chin Jou, Ian Seng Cheong, Hsiu-Ting Tung, Lin-Nei Hsu, Hsin-Tzu Tsai, Tzong-Shin Tzai

“…These findings suggest that phthalate exposure induces Nrf-2 and its downstream signaling (i.e., EGR-1/GDF-15) through microRNA regulation, contributing to prostate cancer aggressiveness.…”
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Development and validation of genome-informed and multigene-based qPCR and LAMP assays for accurate detection of Dickeya solani: a critical quarantine pathogen threatening the pota... by Shefali Dobhal, Gem Santillana, Michael J. Stulberg, Dario Arizala, Anne M. Alvarez, Mohammad Arif

“…ABSTRACT Dickeya solani one of the most aggressive pectinolytic phytopathogens, causes blackleg disease in potatoes, resulting in significant economic losses and adversely impacting one of the world’s most important food crops. …”
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Felix Aderca – scriitorul sub vremuri by Mihaela Iancu

“…His creative effort proved to be unceasing throughout his fifty-year-long career, despite the unfavourable historical times in which he lived: being a Jew, he had to pass through a period of antisemitic policy immediately before and during World War II and he also experienced probably the most aggressive years of the communist regime in Romania under the rule of Gheorghe Gheorghiu-Dej. …”
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Directional entropy based model for diffusivity-driven tumor growth by Marcelo E. de Oliveira, Luiz M. G. Neto

“…In our formulation, the tumor aggressiveness and morphological behavior is tissue-type dependent, i.e. alterations in white and gray matter regions (which can e.g. be induced by normal aging in healthy individuals or neurodegenerative diseases) affect both tumor growth rates and their morphology.The feasibility of this new conceptual approach is supported by previous observations that the fractal dimension, which correlates with the Shannon entropy we calculate, is a quantitative parameter that characterizes the variability of brain tissue, thus, justifying the further evaluation of this new conceptual approach.…”
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Verrucous Carcinoma of Buccal Mucosa in Female: A Rare Case Report of Traumatic Tooth Origin by V. Keerthi Narayan

“…Here, in this paper, we discuss a rare case scenario of a 52-year-old female diagnosed with verrucous carcinoma of the left buccal mucosa with constant traumatic irritation caused by tooth as etiology for the occurrence of lesion, though verrucous carcinoma is described as a benign lesion with minimum aggressive potential but long-standing cases have shown transformation into squamous cell carcinoma. …”
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