Challenges in the Diagnosis and Treatment of Aneurysmal Bone Cyst in Patients with Unusual Features by Ziyad M. Mohaidat, Salah R. Al-gharaibeh, Osama N. Aljararhih, Murad T. Nusairat, Ali A. Al-omari

“…Aneurysmal bone cyst (ABC) is a benign but locally aggressive tumor. It has several challenging features. …”
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Biological functions of extracellular vesicle double C2-like domain beta in cervical cancer by Sangavi Eswaran, Samatha Bhat, Dinesh Upadhya, Roshan Mascarenhas, Shama Prasada Kabekkodu

“…Altogether, EV-mediated DOC2B transfer may reduce the aggressive behavior of CC cells.…”
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Episcleral spread of ciliochoroidal melanoma following surgeries: a case report by E.E. Grishina, I.D. Kim, E.N. Izotova

“…Vladimirskiy Moscow Regional Research and Clinical Institute, Moscow, Russian Federation </p> <p> Uveal melanoma is one of the most aggressive malignant tumors because its metastasis occurs by hematogenous spread. …”
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ADAMDEC1 promotes the malignant progression of cholangiocarcinoma by regulating NF-κB signaling pathway by Shuo Zhou, Yuhang Yang, Feiyu Qi, Wanliang Sun, Dengyong Zhang, Zheng Lu, Yongliang Chen

“…Abstract Cholangiocarcinoma (CCA), a highly aggressive form of cancer, is known for its high mortality rate. …”
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Surgical Treatment Patterns, Healthcare Resource Utilization, and Economic Burden in Patients with Tenosynovial Giant Cell Tumor Who Underwent Joint Surgery in the United States by Feng Lin, Winghan J. Kwong, Sherry Shi, Irina Pivneva, Eric Q. Wu, John A. Abraham

“…**Background:** Tenosynovial giant cell tumors (TGCT) are rare and locally aggressive neoplasms in synovium, bursae, and tendon sheaths, which cause pain, joint dysfunction, and damage to the affected joints. …”
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First-line combination therapy of immunotherapy plus anti-angiogenic drug for thoracic SMARCA4-deficient undifferentiated tumors in AIDS: a case report and review of the literature by Xiaoling Wei, Xiangju Xing, Wei Yao, Changzheng Wang, Yajie Xiao, Xianzhi Du

“…BackgroundThoracic SMARCA4-deficient undifferentiated tumors (SMARCA4-UT) exhibit a notably aggressive phenotype, which is associated with poor patient survival outcomes. …”
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Usefulness of Mechanical Thrombectomy in Patients with Cancer Who Developed Cerebral Infarction by Sayaka TERAZONO, Yuki SAKAEYAMA, Yutaka FUCHINOUE, Masataka MIKAI, Shuhei KUBOTA, Mitsuyoshi ABE, Kosuke KONDO, Nobuo SUGO, Takaaki NAGAO, Masaaki NEMOTO

“…The presence or absence of cancer was not considered an independent factor of mRS(1w), mRS(ENT), or mRS(90 days). Aggressive treatment may be recommended to patients with cancer and/or a history of cancer who present with a systemic condition that can be managed with MT.…”
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THE IMPACT OF FIRM CHARACTERISTICS ON ACCRUALS AND REAL EARNINGS MANGEMENT OF LISTED MANUFACTURING FIRMS IN NIGERIA by Aisha Chado Muhammad

“…Return on assets (ROA), have negative relationship with both AEM and REM which indicates Manager’s aggressive behavior to meet the benchmark has a significant positive association with both AEM and REM. …”
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Causal Association Between Skin Microbiota and Malignant Melanoma: Genetic Insights From Mendelian Randomization by Li X, Wu S, Pan Y, Wu Z, Du Z, Xie W, Zhou Q

“…Xianglong Li,1 Shuang Wu,2 Yujie Pan,3 Ziyan Wu,3 Zhong Du,1 Wanying Xie,1 Qingyu Zhou1 1Department of Medical and Radiation Oncology, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 2Department of Critical Care, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, People’s Republic of China; 3School of Medicine, Yichun University, Yichun, People’s Republic of ChinaCorrespondence: Qingyu Zhou, Email zqy17@foxmail.comBackground: Malignant melanoma (MM) is an extremely aggressive type of skin cancer that represents a major risk to human health. …”
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Health-related quality of life after prosthodontic rehabilitation in patients with COVID-19-associated mucormycosis: A systematic review by Gunjan Chouksey, Rupali Choure, Kritika Singhal

“…COVID-19-associated mucormycosis often necessitates aggressive surgical removal of infected tissues and restoration of the defect. …”
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Identification and Clinical Validation of High HSP60 Expression Predicts Poor Prognosis in Patients with Ovarian Cancer by Zheng M, Li S, Deng J, Huang C, Zhang H

“…Multivariate Cox analysis identified HSP60 as an independent prognostic factor for both overall survival and disease-free survival.Conclusion: High HSP60 expression is associated with poor prognosis and aggressive tumor characteristics in ovarian cancer. …”
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Variation in Botryosphaeriaceae from Eucalyptus plantations in YunNan Province in southwestern China across a climatic gradient by Guoqing Li, Bernard Slippers, Michael J. Wingfield, Shuaifei Chen

“…All the Botryosphaeriaceae species were pathogenic to one-year-old plants of an E. urophylla × E. grandis clone and E. globulus seed-derived plants, but showed significant inter- and intra-species variation in aggressiveness amongst isolates. The study provides a foundation for monitoring and management of Botryosphaeriaceae through selection and breeding of Eucalyptus in the YunNan Province of southwestern China.…”
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Investigating the Relationship between Socioeconomic Status and Traffic Behaviors of Pedestrians in Marand by Sepideh Harzand-Jadidi, Abolfazl Rahimi Bonab, Morteza Haghighi, Mohammad Saadati, Saeid Mousavi

“…The results of the independent t-test showed that the average score of aggressive behavior had a significant relationship with gender. …”
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Performance of GGBS Cement Concrete under Natural Carbonation and Accelerated Carbonation Exposure by Jun Zhao, Eskinder Desta Shumuye, Zike Wang, Gashaw Assefa Bezabih

“…Factors that can substantially affect carbonation resistance of concrete are temperature, relative humidity, cement composition, concentration of external aggressive agents, quality of concrete, and depth of concrete cover. …”
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Comparison of the results of medical approach and surgical approach of septic arthritis in native joints: a single-center retrospective study by Qiyuan Lu, Xiaoqiang Yang, Mengmeng Chen, Zhiqiang Mao, Houfu Ling

“…Maybe the type of bacteria (gram negative or more aggressive ones) can play a role in the choice of treatment strategy. …”
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Basal Cell Carcinoma Diagnosed by Dermoscopy in Dermatology Clinic of the Miguel Enríquez University Hospital by Delia María Gálvez Medina, Yurelbis Loida Lobaina Mejías, Juliette Massip Nicot, Lisbeth Fernández González, Carmen Oraida Tenorio Morión, Dayné Leyva Duthil

“…It is considered locally invasive, also aggressive and destructive. <strong><br />Objective:</strong> to show the behavior of patients with basal cell carcinoma diagnosed by dermoscopy in dermatology clinic of the Miguel Enríquez University Hospital, between June 2020 and May 2021. …”
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Real-World Outcomes of Pralsetinib in RET Fusion-Positive NSCLC by Francesca Lucibello, MD, Valérie Gounant, MD, PhD, Mihaela Aldea, MD, PhD, Michaël Duruisseaux, MD, PhD, Maurice Perol, MD, Christos Chouaid, MD, Jaafar Bennouna, MD, PhD, Vincent Fallet, MD, Aldo Renault, MD, Florian Guisier, MD, PhD, Etienne Giroux-Leprieur, MD, PhD, Marie Wislez, MD, PhD, Anne-Claire Toffart, MD, PhD, Julien Mazieres, MD, PhD, Clémence Basse, MD, PhD, Nadia Hegarat, PhD, Matthieu Carton, MD, Nicolas Girard, MD, PhD

“…We also observe the aggressive nature of disease progression, frequent utilization of chemotherapy and antiangiogenic agents as initial subsequent therapies, and limited insight into resistance mechanisms due to infrequent rebiopsy and genomic profiling at progression.…”
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Ruxolitinib and oHSV combination therapy increases CD4 T cell activity and germinal center B cell populations in murine sarcoma by Ravi Dhital, Yeaseul Kim, Doyeon Kim, Ilse Hernandez-Aguirre, Jack Hedberg, Alexia Martin, Kevin A. Cassady

“…Malignant peripheral nerve sheath tumors (MPNSTs) are a highly aggressive neoplasm of the peripheral nervous system and are resistant to most conventional cancer therapies. …”
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Metformin in COVID-19: a magical role beyond the hyperglycemia by Gaurav Kumar Chaubey, Rahul Dilawari, Radheshyam Modanwal, Sharmila Talukdar, Asmita Dhiman, Manoj Raje

“…Coronavirus disease-2019 (COVID-19) has emerged as an aggressive viral infection in the last few years. Initially reported in the Wuhan area of the People’s Republic of China, it soon emerged across the globe. …”
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Gravity-based microfiltration reveals unexpected prevalence of circulating tumor cell clusters in ovarian and colorectal cancer by Anne Meunier, Javier Alejandro Hernández-Castro, Nicholas Chahley, Laudine Communal, Sara Kheireddine, Newsha Koushki, Nadia Davoudvandi, Sara Al Habyan, Benjamin Péant, Anthoula Lazaris, Andy Ng, Teodor Veres, Luke McCaffrey, Diane Provencher, Peter Metrakos, Anne-Marie Mes-Masson, David Juncker

“…We perform GµF of blood from orthotopic ovarian cancer mouse models and characterize the morphological features of scCTCs and cCTCs, and the expression of molecular markers for aggressiveness. Finally, we analyze blood from 17 epithelial ovarian cancer patients with either localized or metastatic disease, and from 13 colorectal cancer liver metastasis patients. …”
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