Machine learning insights into early mortality risks for small cell lung cancer patients post-chemotherapy by Min Liang, Min Liang, Fuyuan Luo

“…IntroductionSmall cell lung cancer (SCLC) is a highly aggressive form of lung cancer, and chemotherapy remains a cornerstone of its management. …”
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FOXP3 as a prognostic marker and therapeutic target in immunogenic cell death modulation for clear cell renal cell carcinoma by Jian Chen, Cheng Zhu, Yan He, Liping Huang, Weizhuo Wang, Shuaishuai Huang

“…Evaluating ICD patterns in ccRCC may guide patient-specific interventions, paving the way for improved management of this aggressive cancer.…”
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The narrative of the «Northern Territories» in the socio-political discourse of contemporary Japan by D. V. Streltsov

“…Of particular importance from the point of view of the emotional effect on public consciousness are the theses that the Southern Kurils are the “ancestral territory of Japan,” that the USSR committed aggressive and unfair actions against Japan during World War II, and modern Russia did not correct them, and that the Japanese natives of the Southern Kurils experience enormous moral suffering, not having the opportunity to freely visit the graves of their ancestors. …”
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Looking beyond the ER, PR, and HER2: what’s new in the ARsenal for combating breast cancer? by Tryambak Pratap Srivastava, Ruby Dhar, Subhradip Karmakar

“…This review also raises the possibility of using AR splice variants in predicting tumor aggressiveness. From the settings of developing nations, this may provide useful insight by integrating recent advances in AR-targeted therapies and exploring their translational potential, emphasizing the critical need for further research to optimize AR-based therapeutic strategies for breast cancer management.…”
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Scoping review protocol on non-pharmacological interventions for interpersonal and self-directed violence in adults with severe mental illness by Maria Concepcion Moreno-Calvete, Ivan Ruiz-Ibañez, Jose Juan Uriarte-Uriarte

“…Several strategies to reduce the risk of aggressive and violent behaviour have been proposed, and these include non-pharmacological interventions. …”
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Plexin C1 Marks Liver Cancer Cells with Epithelial Phenotype and Is Overexpressed in Hepatocellular Carcinoma by Gorkem Odabas, Metin Cetin, Serdar Turhal, Huseyin Baloglu, A. Emre Sayan, Tamer Yagci

“…Hepatocellular carcinoma is an aggressive malignancy of the liver and is ranked as the sixth most common cancer worldwide. …”
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Squamous Cell Carcinoma of Nasofacial Groove by Tamajit Sau, Saumitra Kumar, Ankita Atin Mukherjee, Debalina Mazumdar

“…It is usually not life-threatening, though it can be aggressive causing serious complications. However, nasofacial groove is a very uncommon area for the origin of squamous cell carcinoma. …”
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Prognostic value of albumin-bilirubin grade in patients with cholangiocarcinoma: a systematic review and meta-analysis by Mahyaar Omouri-Kharashtomi, Seyedeh Yasaman Alemohammad, Negin Moazed, Inas Afzali Nezhad, Hamed Ghoshouni

“…CCA accounts for 10% of primary hepatic cancers and is characterized by its aggressive nature and poor prognosis. This systematic review and meta-analysis aims to assess the prognostic value of the novel hepatic function assessment measure known as albumin-bilirubin (ALBI) grade in patients with CCA. …”
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Extraskeletal Myxoid Chondrosarcoma with Small Bowel Metastasis Causing Bowel Obstruction by Ernesto Bustinza-Linares, Francisco Socola, Vinicius Ernani, Shelly A. Miller, Jonathan C. Trent

“…It has been often described as a low-grade sarcoma although there are certain characteristics like high mitotic activity and the presence of focal regions of Ki67 staining above 25% that correlate with aggressive behavior of the tumor. This is the first case of EMC metastatic to the small bowel to be reported to the medical community.…”
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A Journey into the Complexity of Temporo-Insular Gliomas: Case Report and Literature Review by Manuel De Jesus Encarnacion Ramirez, Gervith Reyes Soto, Carlos Castillo Rangel

“…Introduction: Temporo-insular gliomas, rare brain tumors originating from glial cells, comprise about 30% of brain tumors and vary in aggressiveness from grade I to IV. Despite advancements in neuroimaging and surgical techniques, their management remains complex due to their location near critical cognitive areas. …”
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PPIH is a novel diagnostic biomarker associated with immune infiltration in cholangiocarcinoma by Jun Ye, Zhitao Chen, Chuan Zhang, Rui Xie, Haini Chen, Peng Ren

“…Abstract Background Cholangiocarcinoma (CHOL) is the second most common primary liver malignancy, characterized by high aggressiveness and heterogeneity. It is typically diagnosed at an advanced stage, leading to a poor prognosis. …”
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Clinical implications of Delphian lymph node metastasis in papillary thyroid carcinoma: a single-institution study, systemic review and meta-analysis by Bin Wang, Xing-zhu Wen, Wei Zhang, Ming Qiu

“…In this meta-analysis, there was a strong correlation between Delphian lymph node metastasis and aggressive clinicopathologic characteristics with regards to multifocality (P = 0.0008), bilaterality (P = 0.04), extrathyroid extension (P < 0.00001), lymphovascular invasion (P < 0.00001), further central lymph node metastasis (P < 0.00001) and lateral lymph node metastasis (P < 0.00001). …”
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Mastectomy, HER2 Receptor Positivity, NPI, Late Stage and Luminal B-Type Tumor as Poor Prognostic Factors in Geriatric Patients with Breast Cancer by Demet Nak, Mehmet Kivrak

“…HER2-positive patients exhibited a poorer PFS compared to their HER2-negative counterparts, underscoring the need for careful management of aggressive subtypes in older adults. Additionally, patients undergoing mastectomy were less likely to receive adjuvant therapies, contributing to inferior outcomes compared to breast-conserving surgery (BCS). …”
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Targeting AURKA with multifunctional nanoparticles in CRPC therapy by Bin Deng, Binghu Ke, Qixing Tian, Yukui Gao, Qiliang Zhai, Wenqiang Zhang

“…Abstract Castration-resistant prostate cancer (CRPC) presents significant therapeutic challenges due to its aggressive nature and poor prognosis. Targeting Aurora-A kinase (AURKA) has shown promise in cancer treatment. …”
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Effect of Non-Fumigant Nematicides on Reproduction of Recently Detected <i>Meloidogyne</i> Species in Georgia Under Greenhouse Conditions in Tomato by Nabin Poudel, Luis Torres, Richard F. Davis, Ganpati B. Jagdale, Theodore McAvoy, Intiaz A. Chowdhury

“….; RKNs) are among the most destructive soil-borne pathogens affecting tomato production. Recently, aggressive species such as <i>M. enterolobii</i>, <i>M. floridensis</i>, and <i>M. haplanaria</i> have been reported in several tomato fields across the southern United States. …”
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The Impact and Risk Factors of Screen Time Exposure in Children with Autism Spectrum Disorder by Shahad Ali Ahmed AL-Baldawi, Nabeeha Najatee Akram, Zahraa Aqeel Abdulmajeed

“…For all children, personal data (age, age at diagnosis, sex, sleeping duration at day and night, and aggressive behavior) and both parents' data (age, educational level, and occupation) and screen data (duration of screen exposure, type of device used for, and the content of screening) were collected for each participant. …”
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Pilot study: Initial investigation suggests differences in EMT-associated gene expression in breast tumor regions by Kylie L. King, Hamed Abdollahi, Zoe Dinkel, Alannah Akins, Homayoun Valafar, Heather Dunn

“…Triple negative breast cancer (TNBC) is the most aggressive subtype and disproportionately affects African American women. …”
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Vitamin D Toxicity Managed with Peritoneal Dialysis by Krystel Feghali, Kostas Papamarkakis, Jackson Clark, Neha Malhotra, Lanu Stoddart, Ibitoro Osakwe

“…Cornerstone medical management of hypercalcemia was provided which included aggressive intravenous fluid hydration, intravenous diuretics, calcitonin, bisphosphonate, and corticosteroid therapy. …”
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High expression of nucleotide-binding oligomerization domain protein 1 correlates with poor prognosis and immune cell infiltration in Glioblastoma Multiforme patients by Hongyang Zhao, Beiwu Lan, Zenghui Zhao, Peining Zhu, Chong Wang, Yufei Gao

“…Overall, our findings suggest that NOD1 is a promising prognostic biomarker and is associated with immune cell infiltration in GBM, making it a potential diagnostic biomarker for this aggressive brain cancer.…”
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Asking an AI for salary negotiation advice is a matter of concern: Controlled experimental perturbation of ChatGPT for protected and non-protected group discrimination on a context... by R Stuart Geiger, Flynn O'Sullivan, Elsie Wang, Jonathan Lo

“…Asking for negotiation advice includes how aggressive one ought to be in a negotiation relative to known empirical salary distributions and scales, which is a deeply contextual and personalized task that has no objective ground truth to validate. …”
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