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2021
Machine Learning-Based Classification and Statistical Analysis of Liver Cancer: A Comprehensive Study of Model Performance and Clinical Significance
Published 2024-12-01“…Method: In this study, various models, such as SVM, decision tree, random forest, logistic regression, K-neighbor, Gaussian NB, AdaBoost classifier, MLP classifier, passive aggressive, ridge classifier, extra tree, bagging classifier, extra trees, gradient boosting, SGD classifier, linear SVC, voting classifier, and stacking classifier were used. …”
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2022
Preliminary characterisation of the spatial immune and vascular environment in triple negative basal breast carcinomas using multiplex fluorescent immunohistochemistry.
Published 2025-01-01“…Since little is known about tumour-infiltrating lymphocyte trafficking in triple negative breast cancers, we investigated the relationship between tumour-infiltrating lymphocytes and the vascular compartment to better understand the immune tumour microenvironment in this aggressive cancer type. We aimed to identify mechanisms and signaling pathways responsible for immune cell trafficking in triple negative breast cancers, specifically of basal type, that could potentially be manipulated to change such tumours from immune "cold" to "hot" thereby increasing the likelihood of successful immunotherapy in this challenging patient population. …”
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2023
Rare Case of Multiple Perirenal, Extra-Adrenal Myelolipoma: Case Report, Current Management Options, and Literature Review
Published 2021-01-01“…When these lesions occur outside the adrenals in the retroperitoneum, they are radiographically easily confused with both primary and secondary retroperitoneal tumors, which tend to be aggressive. Although myelolipomas are benign and can be managed conservatively, if malignancy is suspected, a surgical procedure is an option. …”
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2024
Sustaining reductions in postoperative nausea and vomiting after evidence-based practice initiative: A success story
Published 2017-07-01“…Laparoscopic gastric bypass patients remain a high-risk group requiring aggressive multimodal prophylaxis beyond their Apfel simplifi ed risk score.…”
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2025
An analysis of the global burden of gallbladder and biliary tract cancer attributable to high BMI in 204 countries and territories: 1990–2021
Published 2024-12-01“…BackgroundGallbladder and biliary tract cancers (GBTCs) are aggressive with poor prognosis, often undetected until advanced stages. …”
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2026
The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study
Published 2018-01-01“…Inflammatory breast cancer (IBC) is a rare but most aggressive breast cancer subtype. The impact of locoregional therapy on survival in IBC is controversial. …”
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2027
The opposite association of HRAS and KRAS mutations with clinical variables of bladder cancer
Published 2015-12-01“…The data obtained suggest that HRAS and KRAS gene mutations may characterize alternative pathways of bladder cancer pathogenesis: HRAS mutations indicating benign and KRAS mutations, aggressive disease course.…”
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2028
Étude multicritères sur le passage à un régime sans fruits chez les Cébidés et les Cercopithécidés
Published 2024-11-01“…Nutrition and ethology was monitored, including an assessment of the nutritional composition of diets before, during and after diet change; monitoring of faeces consistency; observation of feeding choices; and the occurrence of aggressive behaviour and vocalisations by scan sampling. …”
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2029
The type of infections and the use of antibiotics among patients with rheumatoid arthritis: A review
Published 2025-01-01“…Additionally, it is important to administer vaccinations for specific pathogens (such as pneumococcal, herpes zoster, and influenza) before and during treatment. Aggressive therapy should be pursued to effectively manage disease activity in RA patients, while also maintaining constant vigilance for early signs of infections. …”
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2030
Women's Quality of Life After Surgical Treatment for Breast Cancer
Published 2023-10-01“…<strong>Foundation</strong>: breast cancer requires aggressive treatments such as mastectomy or lumpectomy, followed by radiotherapy or chemotherapy. …”
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2031
Encapsulation of paclitaxel into date palm lipid droplets for enhanced brain cancer therapy
Published 2024-12-01“…Abstract Paclitaxel, a powerful anticancer drug, is limited by its poor water solubility and systemic toxicity, which hinder its effectiveness against aggressive brain tumors. This study aims to overcome these challenges by exploring novel intranasal delivery methods using lipid droplets (LDs) derived from date palm seeds (DPLDs) and mouse liver (MLLDs). …”
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2032
Upregulated Solute Carrier SLC39A1 Promotes Gastric Cancer Proliferation and Indicates Unfavorable Prognosis
Published 2022-01-01“…High SLC39A1 is critical for a more aggressive tumor phenotype by promoting cell proliferation and invasion. …”
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2033
Stromal Expression of Hypoxia Regulated Proteins Is an Adverse Prognostic Factor in Colorectal Carcinomas
Published 2007-01-01“…Background: Hypoxia modifies the phenotype of tumors in a way that promotes tumor aggressiveness and resistance towards chemotherapy and radiotherapy. …”
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2034
Levetiracetam Induced Behavioral Abnormalities in a Patient with Seizure Disorder: A Diagnostic Challenge
Published 2020-01-01“…This research describes the case of a 28-year-old woman with seizure disorder and a psychiatric history of schizoaffective disorder who developed aggressive behavior, paranoia, and severe hostility following administration of Levetiracetam 750 mg orally twice daily. …”
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2035
Streptococcal periorbital necrotizing fasciitis: Case series on a rare but potentially life-threatening entity
Published 2025-01-01“…Conclusions: Based on the negative experience with our first case, we developed a more aggressive surgical plan for cases with periorbital NSTI. …”
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2036
Digital Gangrene: An Unusual Manifestation of Non-Hodgkin Lymphoma
Published 2022-01-01“…The clinical picture varies from indolent to aggressive presentation and nodal (lymphadenopathy) to extranodal (central nervous system, gastrointestinal, cutaneous plaque, or ulcer) involvement. …”
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2037
QoE-Aware Bitrate Selection in Cooperation With In-Network Caching for Information-Centric Networking
Published 2021-01-01“…Only when the user-perceived QoE is expected to be improved, the user application tries to aggressively download high-quality segments from the in-network cache. …”
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2038
Nanoparticles assisted drug delivery for effective management of Glioblastoma
Published 2025-01-01“…Glioblastoma multiforme (GBM) is one of the most aggressive forms of primary brain tumor with a dire prognosis due to its heterogeneity, invasive nature, and resistance to conventional therapies. …”
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2039
Sex differences in borderline personality disorder: A scoping review.
Published 2022-01-01“…Males with BPD were more likely to present externalizing symptoms (e.g., aggressiveness) and comorbid disorders (e.g., substance use), while females with BPD were more likely to present internalizing symptoms (e.g., affective instability) and comorbid disorders (e.g., mood and eating disorders). …”
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2040
HIF-1α Is Associated with Resistance to Hypoxia-Induced Apoptosis in Ameloblastoma
Published 2021-01-01“…Ameloblastoma (AMB) is a benign odontogenic tumour, with an aggressive local behaviour and a high rate of recurrence. …”
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