Therapeutic Potential of Social Chatbots in Alleviating Loneliness and Social Anxiety: Quasi-Experimental Mixed Methods Study by Myungsung Kim, Seonmi Lee, Sieun Kim, Jeong-in Heo, Sangil Lee, Yu-Bin Shin, Chul-Hyun Cho, Dooyoung Jung

“…Quantitative measures were analyzed using analysis of variance and stepwise linear regression to identify the factors affecting change. Thematic analysis was used to analyze user experiences and assess the perceived benefits and challenges of chatbots. …”
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Monocyte STAT1 phosphorylation and treatment response of JAK inhibitors in chronic nonbacterial osteomyelitis by Motoshi Sonoda, Keishiro Kinoshita, Nobutaka Harada, Sungyeon Park, Shunichi Adachi, Yutaro Yada, Katsuhide Eguchi, Toshifumi Fujiwara, Makiko Kido-Nakahara, Noriko Kinjo, Masataka Ishimura, Shouichi Ohga

“…Abstract Background Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory disease of unknown cause, predominantly affecting teens and young adults. The early diagnosis and management are challenging due to the lack of reliable diagnostic markers and the occasional intractable cases despite conventional anti-inflammatory treatments. …”
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From structure prediction to function: defining the domain on the African swine fever virus CD2v protein required for binding to erythrocytes by Ana Luisa Reis, Anusyah Rathakrishnan, Vlad Petrovan, Muneeb Islam, Lynnette Goatley, Katy Moffat, Mai Tuyet Vuong, Yuan Lui, Simon J. Davis, Shinji Ikemizu, Linda K. Dixon

“…African swine fever, a pig disease with fatality rates approaching 100%, causes very substantial economic losses in affected countries, and new control measures are clearly needed. …”
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Predictors of Unfavorable Outcomes in Patients with Atrial Fibrillation and Concomitant Heart Failure with Different Ejection Fractions: RIF-CHF Register One-Year Follow-Up by Igor Zhirov, Natalia Safronova, Yulia Osmolovskaya, Alina Alshevskaya, Andrey Moskalev, Sergey Tereshchenko

“…The geographic and ethnic characteristics of patients may significantly affect the efficacy of different types of therapy and patients’ compliance. …”
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Correlation between Glycated Hemoglobin Levels and Knowledge, Attitude, and Practice of Type 2 Diabetic Patients Attending Primary Health Care Centers in Dubai Health Authority by Hind Al Razooqi, Bashayer AlNajjar, Ebrahim AlShamsi, Kaltham Ibrahim, Wadeia Sharief, Hamda Khansaheb, Marwan Zidan

“…The correlation coefficient between the knowledge score and HbA1c is 0.032 (95% CI [−0.096 to 0.159], p value = 0.628). Factors that affected HbA1c levels were the level of education, marital status, and duration of diabetes (p value: 0.029, 0.003, and 0.006, respectively). …”
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Supplementation of isoacids to lactating dairy cows fed low- or high-forage diets: Effects on performance, digestibility, and milk fatty acid profile by M.R.A. Redoy, S. Ahmed, J. Bonilla Urbina, D.H. Kleinschmit, M.T. Socha, P. Salunke, M.E. Uddin

“…The statistical model included FL, ISO, and FL × ISO as fixed effects and block as a random effect (lme4 in R). The ISO did not affect DMI, and LF cows had greater DMI than HF cows (27.8 vs. 26.0 kg/d). …”
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Estudio genético en adultos con glomeruloesclerosis focal y segmentaria by Melissa Pilco-Terán, Amir Shabaka, Mónica Furlano, Ana Tato Ribera, Isabel Galán Carrillo, Eduardo Gutiérrez, Roser Torra, Gema Fernández-Juárez

“…Abstract: Focal segmental glomerulosclerosis (FSGS) is a histological pattern of injury that derives from various pathological processes that affect podocytes, resulting in loss of selectivity of the glomerular filtration membrane, proteinuria and the development of renal failure that progresses to end-stage kidney disease in a significant number of patients. …”
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Requirement of n-6 and n-3 Fatty Acid in Broodstock Diets on Reproductive Performance of Green catfish, Hemibagrus nemurus Blkr. by Adharto Utiah, M. Zairin Junior, I. Mokoginta, R. Affandi, K. Sumantadinata

“…Results showed that different dietary level of n-6 and n-3 fatty acids of the broodstock significantly affect the reproductive performance especially fecundity and hatching rate of eggs. …”
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Umbilical Cord Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Modulate Skin Matrix Synthesis and Pigmentation by Kee LT, Foo JB, How CW, Nur Azurah AG, Chan HH, Mohd Yunus MH, Ng SN, Ng MH, Law JX

“…Although UC-MSC-sEVs did not alter the proliferation of MNT-1 cells, it did result in a dose-dependent reduction in melanin synthesis without affecting TYR activity. However, when it was applied topically, UC-MSC-sEVs failed to penetrate the skin barrier and remained localized within the stratum corneum layer even after 18 hours.Conclusion: These results highlight the potential of UC-MSC-sEVs in stimulating HDF proliferation, regulating ECM synthesis, and reducing melanin production. …”
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Can exercise as a complementary technique manage inflammatory markers in women with breast cancer who are overweight and obese? A systematic review and meta-analysis by Liang Tan, Jinyu Mei, Ruihong Tang, Duo Huang, Kai Qi, Zbigniew Ossowski, Xiaoning Wang

“…Background: Inflammation can result in the development of breast cancer in women with overweight and obese, and also affects the outcome and prognosis of breast cancer patients, thereby decreasing the cure and survival rates of breast cancer patients. …”
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Research on time–frequency characteristics of electromagnetic signals from coal and rock blasting based on DBO-VMD filtering by Litao WANG, Liming QIU, Menghan WEI, Dazhao SONG, Rentao GOU, Lin LIU, Shiqiang ZHONG, Tianyi XIE

“…In shaft mining, conventional vibration monitoring of blasting operations is often affected by environmental factors and system limitations, complicating the extraction of coal–rock rupture signals. …”
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Development and model test of dynamic loading system in mine goaf site for high-speed railway subgrade by Lianwei REN, Liang LI, Ziqiang WANG, Youfeng ZOU, Zhilin DUN, Shuren WANG

“…The masonry beam structure, which first affects the moving boundary, becomes unstable and activated. …”
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CHANGES IN THE QUALITY OF LIFE AND SEXUAL FUNCTION IN WOMEN WITH PELVIC PROLAPSE AFTER LIGATION OF COLPOPEXY WITH POLYPROPYLENE MESH by A. D. Kaprin, A. A. Kostin, V. B. Filimonov, R. V. Vasin, I. V. Vasina

“…The pelvic organ prolapse in women significantly affects their quality of life and becomes the cause of sexual disorders. …”
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Eu:CROPIS AIV Program: Challenges and Solutions for a Spin-Stabilized Satellite Containing Biology by Toni Delovski, Catherin Düvel, Fabian Greif, Ansgar Heidecker, Sebastian Kottmeier, Olaf Mierheim, Falk Nohka, Fabian Orlowski-Feldhusen

“…These payloads and the system design imposed constraints which affected the Assembly Integration and Verification (AIV) program in various ways and created challenges for the relatively small team to find solutions for. …”
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Construction of the mathematical model of the strength of post-consumer wood made blockboard of different designs by Serhiy Gayda, Lyubomyr Medvid

“…It was found that the width of the strips in blockboard structures with 22 mm thick PCW significantly affects the strength characteristics of the blockboard cores. …”
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Resveratrol contributes to NK cell-mediated breast cancer cytotoxicity by upregulating ULBP2 through miR-17-5p downmodulation and activation of MINK1/JNK/c-Jun signaling by Bisha Ding, Jie Li, Jia-Lin Yan, Chun-Yan Jiang, Ling-Bo Qian, Jie Pan

“…This study aims to investigate how RES affects the expression of ULBP2 and the sensitivity of breast cancer (BC) cells to NK cell cytotoxicity, along with the underlying mechanisms.MethodsThe effects of RES on ULBP2 expression were detected with qRT-PCR, western blot, flow cytometry analysis and immunohistochemistry. …”
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Effects of brown alga, Stoechospermum marginatum extract on growth performance, body chemical compositions and some serum biochemical parameters in grey mullet, Mugil cephalus (Lin... by Nazanin Kiani, Paria Akbary

“…Using algae in the diet of aquatic animals not only reduces the cost of feeding, but also leads to improve the efficiency of aquatic nutrition, digestion, and strengthening the immune system of fish, and by improving the efficiency of digestion, it also affects the quality of water. Given the importance of grey mullet, Mugil cephalus as one of the commercially important fish species and its ability to grow in earthen ponds as well as adapting to a wide range of temperature, salinity and nutritional conditions, in this research, the effect of brown algae, Stoechospermum marginatum extract on growth performance and some biochemical parameters in the grey mullet blood serum were studied for 60 days. …”
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Study on the Regulated Cell Death of Hypertrophic H9c2 Cells Induced by Au:Ag Nanoparticles by Galindo-Padrón AG, Lorenzo-Anota HY, Rueda-Munguía M, García-Carrasco A, Gaitán López M, Vázquez-Garza E, Campos-González E, Lozano O, Cholula-Díaz JL

“…Moreover, the effect of the metal-based nanoparticle exposure on healthy and hypertrophic H9c2 cells was measured by analyzing the cellular vitality, the loss of mitochondrial membrane potential (∆Ψm), and the production of mitochondrial reactive oxygen species (mROS).Results: The Au:Ag NPs did not affect the cell vitality of healthy or metabolically activated macrophages. …”
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Scaling climate information services and climate smart agriculture through bundled business models by Desire M. Kagabo, Livingstone Byandaga, Patrick Gatsinzi, Patrick Mvuyibwami, Yvonne U. Munyangeri, Nasson Ntwari, Mathieu Ouedraogo

“…Eleven CIS-CSA bundled business models with publicly available quantitative scaling readiness data (financial capacity, the number of customers, customer categories, and the number of beneficiaries) were used to quantitatively model how different CIS-CSA products and services bundling strategies, the revenue stream structure of a CIS-CSA business, and the structure of a CIS-CSA business’s stakeholder network (the diversity of its stakeholders) affect its scaling readiness. Based on the scaling readiness evaluation framework, of the 29 identified CIS-CSA bundled business cases, 12 were ready for scaling. …”
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Perancangan dan Implementasi Game Edukasi Kesehatan Gigi “Tooth and Fairy” berbasis Android Menggunakan Unity Engine by Sussi Sussi, Sri Astuti, Nurwulan Fitriyanti, Nyoman Bogi Aditya Karna, Nizar Rizky Awany, Muhammad Fajar Firdiansyah, Rafli Noveri Alfariji, Dhea Dearly Herman, Muhammad Risqi Risfianda, Muh Nurkhaliz

“…Abstract Education about dental health needs to be taught from an early age because healthy living habits from childhood will affect adulthood. Parents can start knowledge about healthy teeth by providing information about spoilage foods and supporting dental health. …”
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