Development of normal reference intervals for renal function in pregnancy: a secondary analysis of clinical trial data by Zandile Legoabe, Motshedisi Sebitloane, Carl Lombard, Megeshinee Naidoo, Glenda Gray, Dhayendre Moodley

“…Background Due to its potential nephrotoxicity, screening for pre-existing renal function disorders has become a routine clinical assessment for initiating Tenofovir diphosphate fumarate (TDF)-containing antiretroviral treatment (ART) or pre-exposure prophylaxis (PrEP) in pregnant and non-pregnant adults. We aimed to establish reference values for commonly used markers of renal function in healthy pregnant women of African origin.Methods Pregnant women ≥18 years, not living with HIV, and at 14–28 weeks gestation were enrolled in a PrEP clinical trial in Durban, South Africa between September 2017 and December 2019. …”
Get full text

The impact of age on comparative diagnostic accuracy of temporal artery thermometers and non-contact infrared thermometers for fever detection: a systematic review and meta-analysi... by Kwo-Chen Lee, Yun-Ping Lin, Ya-Ling Tzeng, Wen-Chun Liao, Chyi Lo, Pei-Yun Chen, Shu-Hua Lu

“…Sensitivity was higher at fever thresholds > 38 °C (0.71, 95% CI: 0.60–0.80), and higher in children (0.77, 95% CI: 0.66–0.85) than in adults (0.48, 95% CI: 0.30–0.67). Similar sensitivities were observed between rectal and other standards (0.70, 95% CI: 0.59–0.80 vs. 0.70, 95% CI: 0.41–0.89). …”
Get full text

Determination of Seroprevalence and Risk Factors of Crimean–Congo Haemorrhagic Fever (CCHF) in the Endemic Region in Turkey: A Population-Based Cross-Sectional Study by Rıza Çıtıl, Mücahit Eğri, Yalçın Önder, Fazilet Duygu, Yunus Emre Bulut, Özkan Yaşayancan, Nagehan Yıldız Çeltek, Şafak Şahin

“…The aim of the study was to determine the seroprevalence and risk factors of CCHF in adults aged ≥20 years in Tokat in the endemic region, Turkey. …”
Get full text

Beverage consumption modifies the risk of type 2 diabetes associated with ambient air pollution exposure by Chaonan Fan, Wenjuan Wang, Wenxue Xiong, Zhiyao Li, Li Ling

“…Methods: A total of 77,278 adults from the UK Biobank cohort were enrolled. Annual average concentrations of fine particulate matter (PM2.5 and PM10) and nitrogen oxides (NO2 and NOX) were estimated to represent the long-term AP exposure using the land use regression model. …”
Get full text

Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States by Qu Zhang, Yemei Wu, Bo Luo

“…LOBS was associated with reductions across WC, BP, FG, TG, and an increase in HDL-C.ConclusionOBS is inversely associated with MetS in middle-aged and older U.S. adults. Enhancing OBS through dietary guidelines emphasizing antioxidant-rich foods, fiber, and unsaturated fats, alongside lifestyle changes like regular exercise, smoking cessation, and moderate alcohol intake, may be crucial in MetS prevention for this population.…”
Get full text

Penyeimbangan Kelas SMOTE dan Seleksi Fitur Ensemble Filter pada Support Vector Machine untuk Klasifikasi Penyakit Liver by Muhammad Amir Nugraha, Muhammad Itqan Mazdadi, Andi Farmadi, Muliadi, Triando Hamonangan Saragih

“…Quoting an article from the American Liver Foundation website, in 2020, as many as 51,642 adults in the United States died from liver disease. …”
Get full text

Wearable Loop Sensors for Knee Flexion Monitoring: Dynamic Measurements on Human Subjects by Ian Anderson, Christopher Cosma, Yingzhe Zhang, Vigyanshu Mishra, Asimina Kiourti

“…<italic>Methods:</italic> Three dynamic activities (walking, brisk walking, and full flexion&#x002F;extension, all performed in place) are used to validate the tethered sensor on ten (10) adults. The untethered sensor is validated upon a cylindrical phantom that is bent manually at random speed. …”
Get full text

Association of lung health and cardiovascular health (Life’s Essential 8) by Wanjia Zhang, Menglong Zou, Junyao Liang, Dexu Zhang, Man Zhou, Hui Feng, Chusen Tang, Jie Xiao, Zhan Yi, Yin Xu

“…Among middle-aged and older adults (age &gt; 40), the high LE8 group had significantly lower odds of respiratory symptoms, including cough (OR = 0.23; 95% CI = 0.12, 0.46), phlegm (OR = 0.42; 95% CI = 0.19, 0.90), and wheezing (OR = 0.29; 95% CI = 0.15, 0.54). …”
Get full text

Informal Caregivers Connecting on the Web: Content Analysis of Posts on Discussion Forums by Michelle L Foster, Chinenye Egwuonwu, Erin Vernon, Mohammad Alarifi, M Courtney Hughes

“… Abstract BackgroundAbout 53 million adults in the United States offer informal care to family and friends with disease or disability. …”
Get full text

ChatGPT’s Attitude, Knowledge, and Clinical Application in Geriatrics Practice and Education: Exploratory Observational Study by Huai Yong Cheng

“…The mean subscore on positive geriatrics attitude of ChatGPT was higher than that of the trainees (medical students, internal medicine residents, and neurologists; 4.1 vs 3.7 on a scale from 1 to 5 where a higher score means a more positive attitude toward older adults). The mean subscore on negative geriatrics attitude of ChatGPT was lower than that of the trainees and neurologists (1.8 vs 2.8 on a scale from 1 to 5 where a lower subscore means a less negative attitude toward aging). …”
Get full text

Promoting trans patient autonomy in surgical preparation for phalloplasty and metoidioplasty: results from a community-based cross-sectional survey and implications for preoperativ... by Leo L. Rutherford, Elijah R. Castle, Noah Adams, Logan Berrian, Linden Jennings, Ayden Scheim, Aaron Devor, Nathan J. Lachowsky

“…Methods This study sought to fill this gap by utilizing data from PROGRESS (Patient-Reported Outcomes of Genital Reconstruction and Experiences of Surgical Satisfaction), a cross-sectional, community-based survey of trans and nonbinary adults from the United States of America and Canada who had undergone one or more of these surgeries. …”
Get full text

Acute Concurrent Exercise Improves Inhibitory Control Without Mediating the Role of Lactate: An Event-Related Potential Study by Ruei-Hong Li, Tai-Rui Chen, Nicholas D. Gilson, Marius Brazaitis, Yi-Ting Cheng, Hui-Fang Wu, Ji-Hang Lee, Yu-Kai Chang

“…Methods Seventy-eight adults (mean age = 22.95, SD = 1.75 years) were randomly assigned to either a CE, AE, or control (CON) group. …”
Get full text

Efficacy of drugs most commonly prescribed at functional gastrointestinal diseases (functional dyspepsia syndrome and irritable bowel syndrome) observational study results by V. T. Ivashkin, Ye. A. Poluektova, D. V. Reykhart, O. S. Shifrin, A. G. Beniashvili, O. S. Lyashenko, A. V. Belostotsky

“…Later all patients underwent a set of laboratory and instrumental tests required according to «Guidelines on diagnostics and treatment of the irritable bowel syndrome in adults» of the Russian gastroenterological association and Russian Association of coloproctology and to «Clinical guidelines on diagnostics and treatment of the functional dyspepsia» of the Russian gastroenterological association. …”
Get full text

Consumption of Raw Herbal Medicines Is Associated with Major Public Health Risks amongst Ugandans by Fred, Ssempijja, Keneth Iceland, Kasozi, Ejike, Daniel Eze, Andrew, Tamale, Sylvia Anurika, Ewuzie, Kevin, Matama, Justine, Ekou, Paul, Bogere, Regan, Mujinya, Grace Henry, Musoke, Jovile Kasande, Atusiimirwe, Gerald, Zirintunda, Muhamudu, Kalange, Joel, Lyada, Ritah, Kiconco, Theophilus, Pius, Christopher, Nandala, Roland Mugisha, Kamugisha, Yunusu, Hamira, Edgar Mario, Fernandez, Simon Peter, Musinguzi

“…+e EDI was significantly higher in children than in adults, demonstrating an increased risk of toxicity in children. …”
Get full text

Functional status, lymphocyte-to-monocyte ratio, and platelet-to-lymphocyte ratio as prognostic factors of one-year survival rate in elderly patients with advanced-stage non-small... by Ratna Nurhayati, Aulia Rizka, Cleopas Martin Rumende, Noorwati Sutandyo, Arif Hanafi, Edy Rizal Wahyudi, Hamzah Shatri, Anna Mira Lubis, Em Yunir, Muhammad Firdaus, Yuniar Harris Prayitno, Nadira Nibras Taqiyya

“…Functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio describe a chronic inflammation and correlate to the survival of older adults with advanced-stage (IIIB-IV) NSCLC. This study aims to determine functional status, lymphocyte-to-monocyte ratio and platelet-to-lymphocyte ratio as prognostic factors to 1-year survival in elderly patients with NSCLC stage IIIB-IV. …”
Get full text

Frequency of consumption and factors associated with hookah use in Curitiba, Brazil: a cross-sectional study by Heloisa Franco de Meira, Paulo Henrique Couto Souza, Juliana Schaia Rocha Orsi, Fernanda Tiboni, Sérgio Aparecido Ignácio, Constanza Andrea Hernandez Meza, Flávia Sukekava, Arieli Carini Michels, Amanda Dallegrave Vicentin, Patricia Lupion Torres, Emanuela Carla dos Santos, Mariana Hornung Marins, Aldini Beuting Pereira, Paula Cristina Trevilatto, Aline Cristina Batista Rodrigues Johann

“…Methods This cross-sectional study involved adults, hookah users, residing in the city of Curitiba. …”
Get full text

Knowledge, attitudes and behaviour towards ticks and tick-borne diseases—A survey among Lyme borreliosis cases in Bavaria in 2019 by Stefanie Böhm, Volker Fingerle, Andreas Beyerlein, Manfred Wildner, Merle M. Böhmer

“…Questions included socio-demographic characteristics, experiences with TBDs, potential tick exposures, details of the recent episode of LB, and knowledge, attitudes, and behaviours regarding TBDs and protection measures.Among the 377 participants, 300 were adults/adolescents, 77 were children (<14 years). …”
Get full text

START—the Swiss tele-assisted rehabilitation and training program to support transition from inpatient to outpatient care in the subacute phase after a stroke: feasibility, safety... by Szabina Gäumann, Carina Ziller, Carina Ziller, Nele Paulissen, Nele Paulissen, Frank Behrendt, Frank Behrendt, Zorica Suica, Zorica Suica, Björn Crüts, Luana Gammerschlag, Katrin Parmar, Katrin Parmar, Hans Ulrich Gerth, Hans Ulrich Gerth, Leo H. Bonati, Leo H. Bonati, Leo H. Bonati, Corina Schuster-Amft, Corina Schuster-Amft, Corina Schuster-Amft

“…Potential challenges include patient self-reporting via the mobile application and barriers related to technology use among older adults and older mobile devices. Additionally, the availability of coaching is limited to business hours, which may affect adherence. …”
Get full text

How learning to read Braille in visual and tactile domains reorganizes the sighted brain by Maciej Gaca, Alicja M. Olszewska, Dawid Droździel, Agnieszka Kulesza, Małgorzata Paplińska, Bartosz Kossowski, Katarzyna Jednoróg, Jacek Matuszewski, Aleksandra M. Herman, Artur Marchewka

“…Our study involved 17 sighted adults who learned Braille for 7 months and 19 controls. …”
Get full text

Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis by Yong-Li Zhao, Yi-Ning Hao, Yi-Jun Ge, Yi Zhang, Lang-Yu Huang, Yan Fu, Dan-Dan Zhang, Ya-Nan Ou, Xi-Peng Cao, Jian-Feng Feng, Wei Cheng, Lan Tan, Jin-Tai Yu

“…Methods Our study included 164,463 non-demented adults (89,644 [54.51%] female; mean [SD] age, 56.69 [8.14] years) from the UK Biobank who completed four cognitive assessments at baseline. 364 variables were finally extracted for analysis through a rigorous screening process. …”
Get full text