Serial measurements in COVID-19-induced acute respiratory disease to unravel heterogeneity of the disease course: design of the Maastricht Intensive Care COVID cohort (MaastrICCht) by Steven J R Meex, Walther N K A van Mook, Iwan C C van der Horst, Jeanette Tas, Coen D A Stehouwer, Rob J J van Gassel, Serge J H Heines, Mark M G Mulder, Nanon F L Heijnen, Melanie J Acampo-de Jong, Julia L M Bels, Frank C Bennis, Marcel Koelmann, Rald V M Groven, Moniek A Donkers, Frank van Rosmalen, Ben J M Hermans, Otto Bekers, Astrid M L Oude Lashof, Fabian H Tijssen, Jan-Willem E M Sels, Chahinda Ghossein-Doha, Rob G H Driessen, Pieter L Kubben, Marcus L F Janssen, Gerry A F Nicolaes, Ulrich Strauch, Zafer Geyik, Thijs S R Delnoij, Kim H M Walraven, Jeanine A M C F Verbunt, Susanne van Santen, Ronny M Schnabel, Marcel J H Aries, Marcel C G van de Poll, Bas C T van Bussel, Joachim E Wildberger, Sander M J van Kuijk, Dennis C J J Bergmans, Paul H M Savelkoul, Alma M A Mingels, Wolfgang F F A Buhre

“…The results will be published in peer-reviewed academic journals, with a preference for open access journals, while particularly considering deposition of the manuscripts on a preprint server early.Trial registration number The Netherlands Trial Register (NL8613).…”
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Identification of strengths and weaknesses of the healthcare system for persons living with rare diseases in Catalonia (Spain), and recommendations to improve its comprehensive att... by José Hernández-Rodríguez, Fernando Martínez-Valle, Xènia Acebes, Carmen Alerany, Jordi Antón, Gonzalo Calvo, Marian Corral, Jordi Cruz, M. Antònia Mangues-Bafalluy, José Mateo, Josefa Rivera, Albert Salazar, Roser Francisco, Cristina Mallol, Rita Reig-Viader, Ariadna Tigri-Santiña, Assumpta Ricart, Francesc Palau

“…The problems found in the current healthcare model were grouped into ten main areas: (1) the healthcare model for RDs; (2) coordination with primary healthcare providers and other tertiary and secondary hospitals; (3) access to and coordination with non-medical services; (4) the role of case manager in the XUEC; (5) genetic diagnosis; (6) undiagnosed patients; (7) treatments; (8) referring process, continuous follow-up, and transition from pediatric to adult centers; (9) research and education for professionals; and (10) associations of PLWRD and their families (patients’ advocacy). …”
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Refining Established Practices for Research Question Definition to Foster Interdisciplinary Research Skills in a Digital Age: Consensus Study With Nominal Group Technique by Jana Sedlakova, Mina Stanikić, Felix Gille, Jürgen Bernard, Andrea B Horn, Markus Wolf, Christina Haag, Joel Floris, Gabriela Morgenshtern, Gerold Schneider, Aleksandra Zumbrunn Wojczyńska, Corine Mouton Dorey, Dominik Alois Ettlin, Daniel Gero, Thomas Friemel, Ziyuan Lu, Kimon Papadopoulos, Sonja Schläpfer, Ning Wang, Viktor von Wyl

“…We propose 3 clusters of contextual and methodological adaptations to this workflow to better integrate data science practices: (1) acknowledging real-life constraints and limitations in research scope; (2) allowing more iterative, data-driven approaches to research question formulation; and (3) strengthening research quality through reproducibility principles and adherence to the findable, accessible, interoperable, and reusable (FAIR) data principles. …”
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Optimization and characterization studies of poultry waste valorization for peptone production using a newly Egyptian Bacillus subtilis strain by Hajar Saeed, Anthony Ragaey, Ziad Samy, Viola Ashraf, Aly ElMostafa, Norhan Ahmad, Enjy Bebawy, Nour ElHoda M. Sorour, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa El-Noby, Samah H. Abu-Hussien

“…The isolation process yielded the highly potent proteolytic B.subtilis isolate P6, identified through 16S rRNA gene sequencing to share 94% similarity with the B.subtilis strain KEMET024 (GenBank accession number PP694485.1) and deposited in MIRCEN culture collection, Cairo, Egypt as EMCC 998871. …”
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Maternal exposure to dim light at night induces behavioral alterations in the adolescent and adult offspring Wistar rat by Shellye González-González, Mariana Gutiérrez-Pérez, Mara A. Guzmán-Ruiz, Estefania Espitia-Bautista, Rosa María Pavón, Karla P. Estrada-Rodríguez, Alejandro Díaz-Infante R., Cecilia G. Guadarrama Gándara, Carolina Escobar, Natalí N. Guerrero-Vargas

“…IntroductionAccess to electric light has exposed living organisms to varying intensities of light throughout the 24 h day. …”
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Development and usability testing of a multifaceted intervention to reduce low-value injury care by Mélanie Bérubé, Alexandra Lapierre, Michael Sykes, Jeremy Grimshaw, Alexis F. Turgeon, François Lauzier, Monica Taljaard, Henry Thomas Stelfox, Holly Witteman, Simon Berthelot, Éric Mercier, Catherine Gonthier, Jérôme Paquet, Robert Fowler, Natalie Yanchar, Barbara Haas, Paule Lessard-Bonaventure, Patrick Archambault, Belinda Gabbe, Jason R. Guertin, Yougdong Ouyang, Lynne Moore, the Canadian Traumatic Brain Injury Research Consortium

“…Results We identified barriers and facilitators related to individual characteristics, including knowledge and beliefs about low-value practices and the de-implementation process, such as the complexity of changing practices and difficulty accessing performance feedback. Accordingly, the following intervention strategies were selected: involving governing structures and leaders, distributing audit & feedback reports on performance, and providing educational materials, de-implementation support tools and educational/facilitation visits. …”
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Integrated transcriptomic hypothalamic-pituitary-ovarian axis network analysis reveals the role of energy availability on egg production in layers by Jianling Peng, Yong Cui, Haiping Liang, Shenyijun Xu, Linjian Weng, Meng Ru, Ramlat Ali, Qing Wei, Jiming Ruan, Jianzhen Huang

“…To investigate the mechanism of integrated network regulation of the HPO axis under energy fluctuation, ninety Hy-line brown layers (265-day-old, 1.92 ± 0.02 kg) were randomly divided into three groups for a 17-day experiment: a control group (Con group) fed ad libitum from days 1 to 17, an energy-deprived group (ED group) that was fed ad libitum from days 1 to 12 and then underwent a fasting period from days 13 to 17 to induce a pause in laying, and a re-fed group (Rf group) that fasted for seven days (specifically, days 1 to 5, day 7, and day 9), had ad libitum access to feed on days 6 and 8, and was continuously fed from days 10 to 17. …”
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Analytical and Comparative Analysis of Copper Industry Development Programs in Iran by Adel Rouhi Jouybari, Seyed Mohammad Esmaiel Jalali

“…Methods The most important challenges in the copper industry in Iran include problems related to sanctions and the resulting lack of access to modern technologies, lack of support for small and medium-sized businesses, price differences in the commodity exchange and free market and their impact on the trade market and copper products, and the level of access of consumers to the market. …”
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Designing and Explaining the Competence Model of Knowledge Engineers in Municipalities (Study Case: Tehran Municipality) by Amin Seyyed Nosrati, Zahra Foroutani, Atyieh Bohrani

“…The role of a knowledge engineer is pivotal in capturing and codifying the tacit knowledge held by employees, making it accessible and preserving it within the organization. …”
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Medication adherence and blood pressure control in treated hypertensive patients: first follow-up findings from the PREDIcT-HTN study in Northern Bangladesh by Ahmed Hossain, Gias Uddin Ahsan, Mohammad Zakir Hossain, Mohammad Anwar Hossain, Probal Sutradhar, Sarowar-E. Alam, Zeeba Zahra Sultana, Heba Hijazi, Syed Azizur Rahman, Mohamad Alameddine

“…These efforts align with the UN's 2030 SDGs, emphasizing targeted interventions for equitable healthcare access and outcomes.…”
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Dairy cows' responses to 2 separation methods after 3 months of cow-calf contact by Anina Vogt, Susanne Waiblinger, Rupert Palme, Uta König von Borstel, Kerstin Barth

“…Milk yield was higher in NF than GR cows during the 2 wk while GR calves had time-restricted access to their dams and NF calves were prevented from suckling, but showed no difference afterward. …”
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Status of Digital Health Technology Adoption in 5 Vietnamese Hospitals: Cross-Sectional Assessment by Duc Minh Tran, Nguyen Thanh Dung, Chau Minh Duc, Huynh Ngoc Hon, Le Minh Khoi, Nguyen Phuc Hau, Duong Thi Thu Huyen, Huynh Thi Le Thu, Tran Van Duc, Lam Minh Yen, C Louise Thwaites, Chris Paton

“…Although the adoption of EMR systems is less common, their implementation revolves around data collection, management, and access to clinical data. Secondary use of clinical data for decision support through the implementation of CDRs and CDSS is limited, posing a potential barrier to the integration of external DHTs into the existing systems. …”
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Un service de table en bronze et argent soigneusement rangé dans une cave à Reims/Durocortorum by Michaël Brunet, Fabienne Médard, Magalie Cavé, Stéphane Sindonino

“…The cellar is rectangular, with a rectilinear access hallway, in its northwestern corner. It measures over 6 m in length, including the cellar descent, and 3.85 m in width. …”
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Resident-based learning model for sustainable resident participation in municipal solid waste management program by A. Ghazali, J. Tjakraatmadja, . Sunarti, E.Y.D. Pratiwi

“…==========================================================================================COPYRIGHTS©2021 The author(s). This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, as long as the original authors and source are cited. …”
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Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada by Jorge L. Martinez-Cajas, Ann Jolly, Yanping Gong, Gerald Evans, Santiago Perez-Patrigeon, Bradley Stoner, T. Hugh Guan, Beatriz Alvarado

“…We employed Poisson regression for period #1 and Cox regression for period #2 to examine associations of demographic factors (age, sex, ethnicity, migration status, income insufficiency), health factors (chronic conditions, smoking history, SARS-CoV-2 vaccination status), household factors (exposure to COVID-19), occupational factors (work role, exposure to COVID-19 patients, personal protective equipment access, aerosol-generating procedures) and community exposures (use of masks, distance, hand-washing) with SARS-CoV-2 infection. …”
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Le port antique de Chelles (Seine-et-Marne) : une course après la rivière by Yann Le Jeune, Corinne Charamond, Christian Charamond

“…The riverbanks sustained various activities and endeavors aimed at maintaining access to water –digging, dredging, depositing backfill, and more advanced developments toward the north in hopes of following the river– an effort which could not be maintained for more than a century and which reflects a veritable race after the river. …”
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Investigating the Role of the basic Components of Smart Governance in Realizing a Smart City with the ISM Method (Case Study: Tehran) by ALi Asghar Pourezzat, Tayebeh Abbasi, Shahryar Maghsoodi Kenari, Mohammad Mehdi Namdar Joybari

“…After reviewing the research background and conducting in-depth interviews, several critical components were identified, including citizen participation, e-government, smart management, technology utilization, the political and institutional environment, internet access and usage, socio-environmental characteristics, transparency, accountability, data exchange, and public-private sector collaboration. …”
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Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)—an mHealth Application for the Universal Screening of Alcohol, Substance Use, D... by Krystyna Isaacs, Autumn Shifflett, Kajal Patel, Lacey Karpisek, Yi Cui, Maayan Lawental, Golfo Tzilos Wernette, Brian Borsari, Katie Chang, Tony Ma

“… BackgroundWomen of childbearing age (aged 18-44 years) face multiple barriers to receiving screening and treatment for unhealthy alcohol and substance use, depression, and anxiety, including lack of screening in the primary care setting and lack of support in accessing care. The Women Empowered to Connect with Addiction Resources and Engage in Evidence-based Treatment (WE-CARE) mobile app was developed to test universal screening with women of childbearing age and linkage to care after an anonymous assessment. …”
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The Effect of Combining mHealth and Health Professional–Led Intervention for Improving Health-Related Outcomes in Chronic Diseases: Systematic Review and Meta-Analysis by Masashi Kanai, Takahiro Miki, Toshiya Sakoda, Yuta Hagiwara

“…This has led to the exploration of innovative solutions, such as mobile health (mHealth) technologies. mHealth, which leverages mobile and wireless technologies, has the potential to transform health care delivery by providing continuous, accessible, and personalized care. However, the effectiveness of mHealth, particularly when integrated with traditional health care interventions delivered by professionals, warrants comprehensive investigation. …”
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Impact of cariprazine on body weight and blood pressure among adults with bipolar I disorder, schizophrenia, or major depressive disorder in a real-world setting by Christoph U. Correll, Andrew J. Cutler, François Laliberté, Guillaume Germain, Sean D. MacKnight, Julien Boudreau, Sally W. Wade, Nadia Nabulsi, Huy-Binh Nguyen, Mousam Parikh

“…Methods Symphony Health’s Integrated Dataverse® with electronic medical record access (3/1/2015–10/31/2018) was used to identify adults (≥ 18 years) diagnosed with BP-I depression, BP-I mania/mixed, schizophrenia, or MDD, with ≥ 2 cariprazine dispensings (first dispensing = index) and continuous clinical activity for ≥ 12 months pre-index (baseline) and ≥ 3 months post-index. …”
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