Evaluation of the implementation in primary care of genetic testing for the screening of MODY2 (iMOgene): protocol for an implementation pilot study by Marie-Ève Poitras, Luigi Bouchard, Samuel Legeay, Vanessa Tremblay-Vaillancourt, Amélie Fournier, Josianne Leblanc, Philippe Caron, Catherine Savard, Nathalie Bettez, Karine Tremblay

“…Genetic testing for the diagnosis of MODY2 is currently reserved for genetic specialists and some physicians. Still, access to it by primary care healthcare professionals (HCPs), coupled with appropriate training, would improve the diagnosis and management of patients with MODY2. …”
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Midwives’ knowledge and perspectives on neonatal resuscitation and survival before and after Helping Babies Breathe training: a qualitative study in Uganda by Anna Bergstrom, Josaphat Byamugisha, Susanna Myrnerts Höök, Marielle Abrahamsson, Sarah Namusoko

“…Excessive workload, limited access to clean equipment, and ethical dilemmas hampered performance and neonatal survival. …”
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Experiences Using Media Health Claims to Teach Evidence-Based Practice to Healthcare Students: A Mixed Methods Study [version 3; peer review: 2 approved, 2 approved with reservatio... by Astrid Dahlgren, Marianne Molin, Jürgen Kasper, Lisa Garnweidner-Holme, Hilde Tinderholt Myrhaug, Ida-Kristin Orjasaeter Elvsaas

“…In this context, we advocate the strategic use of health claims in media to promote critical thinking and provide an accessible entry point to evidence-based practice for early-stage university healthcare students. …”
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Evaluating catastrophic health expenditures among patients with long bone fractures in Ghana's major teaching hospitals: a hospital-based analysis by Alexis D. B. Buunaaim, Michel Adurayi Amenah, Dominic Konadu-Yeboah, Richard Baidoo, Amgbo Asare, Wilfred Larbi Addo, Claude Martin

“…Abstract Background In low and middle-income countries like Ghana, out-of-pocket (OOP) payments remain a significant barrier to healthcare access, often leading to catastrophic health expenditures (CHE). …”
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How climate change is shaping young people’s health: a participatory, youth co-led study from Bangladesh, Guatemala and Nigeria by Jessie Pinchoff, Karen Austrian, Eno-Obong Etetim, Damilola Babatunde, Eleanor Blomstrom, Sigma Ainul, Toyin Olamide Akomolafe, Brian Medina Carranza, Angel Del Valle

“…Using NVivo software, translated transcripts were coded to explore and synthesise key thematic areas.Results Respondents discussed varied climate exposures and associated health risks, for example, how flooding events were impeding access to sexual and reproductive health commodities. …”
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A participatory needs assessment to map the system dynamics of overweight related behaviours of 10-14-year-old adolescents living in an underserved neighbourhood in Amsterdam, the... by Helga Emke, Rabab Chrifou, Coosje Dijkstra, Wilma Waterlander, Karien Stronks, Stef Kremers, Mai Chinapaw, Teatske Altenburg

“…The adolescents explained that their physical environment fosters unhealthy behaviour by providing easy access to unhealthy food products while restricting physical activity. …”
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Is the groundwater of Dhaka city, Bangladesh contaminated with naturally occurring potential toxic elements? by Mahir Tajwar, Mahfuzur Rahman, Mahfuzur Rahman, Shamiha Shafinaz Shreya, Nazmus Sakib, Md. Yousuf Gazi, Md. Yousuf Gazi, Mahmudul Hasan, Anika Samm-A, Anwar Zahid

“…This study highlights groundwater contamination as a critical public health concern and advocates the need for mitigation efforts to ensure safe drinking water access. The study underscores the urgent need for implementing stricter groundwater management policies and public health interventions to mitigate contamination risks.…”
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“I’m living in a ‘no’ world now…”- A qualitative study of the widespread impact of living with chronic breathlessness, and experiences of identification and assessment of this symp... by Helene L. Elliott-Button, Miriam J. Johnson, Ann Hutchinson, David C. Currow, Joseph Clark

“…Evidence-based breathlessness interventions are available, but not routinely implemented with few patients accessing them. Proactive identification, assessment and management of breathlessness in primary care is needed to support adults living with chronic breathlessness.…”
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The impact of delay in HIV diagnosis on patient survival: analysis of HIV infection trends from 2007 to 2023 by Riyaz A. Shaik, Sharan K. Holyachi, Mohammad S. Ahmad, Mohammed Miraj, Syed Yousaf Kazmi, Mohammad Rehan Asad, Ali Faraz, Mirwais Ramozi, Ritu Kumar Ahmad

“…Programs to increase awareness and access to diagnostic and treatment services should be strengthened.…”
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Effects of home-based mirror therapy and cognitive therapeutic exercise on the improvement of the upper extremity functions in patients with severe hemiparesis after a stroke: a pr... by Josefa Gonzalez-Santos, Raul Soto-Camara, Paula Rodriguez-Fernández, Maria Jimenez-Barrios, Jeronimo Gonzalez-Bernal, Carla Collazo-Riobo, Maha Jahouh, Yolanda Bravo-Anguiano, Jose M Trejo-Gabriel-Galan

“…The results will be disseminated through open-access peer-reviewed journals, conference presentation, broadcast media and a presentation to stakeholders. …”
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Comparison of Accounting Profit Between Offshore and Deep-sea Commercial Fishing Industry in Pahang State, East Coast of Peninsular Malaysia by Moe Shwe Sin, Lavaniya Gopabala Krishnan, Shzee Yew Tai, Azlina Abd Aziz, Mahirah Kamaludin

“…Moreover, there are more trawlers vessels operating in the Pahang state fishing ground and the open access nature of the fishery like larger profit invites more effort to use in the fishery which is leading to the over exploitation of fishery resources and threatening the sustainable condition of the fishery. …”
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The effect of lavender inhalation aromatherapy on systolic and diastolic blood pressure in patients with prehypertension by Amir Musarezaie, Mohammad Javad Tarrahi, Masoumeh Sadeghi, Sedigheh Farzi, Tahere Momeni-Ghale Ghasemi, Amir Hossein Saeidi, Maryam Sadat Shahshahani

“…Conclusion: Considering the rising trend of high blood pressure and its widespread complications, along with the positive effects of aromatherapy as a cost-effective and accessible intervention, lavender inhalation aromatherapy is recommended as a complementary treatment strategy in conjunction with other methods.…”
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Identification of critical biomarkers and immune landscape patterns in glioma based on multi-database by Hanzhang Yuan, Jingsheng Cheng, Jun Xia, Zeng Yang, Lixin Xu

“…CellMiner was used to access the correlation between the expression of potential biomarkers and anticancer drug sensitivity. …”
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Enhancing furcation involvement classification on panoramic radiographs with vision transformers by Xuan Zhang, Enting Guo, Xu Liu, Hong Zhao, Jie Yang, Wen Li, Wenlei Wu, Weibin Sun

“…Conclusion DL algorithms can automatically classify FI using readily accessible panoramic images. These findings demonstrate that ViT outperforms the tested traditional models, highlighting the potential of transformer-based approaches to significantly advance image classification. …”
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Brain radiotherapy and dorsal vagal complex irradiation: A new organ at risk to decrease radiation-induced nausea and vomiting? by Valentine Caspar, Nicolas Giraud, Thomas Charleux, Arnaud Beddok, Brieuc Bernard, Maelle Martin, Juliette Thariat, Aymeri Huchet, Véronique Vendrely, Charles Dupin

“…Material: Details of consecutive patients treated for benign brain tumors at the Bordeaux University Hospital using normofractionated intensity modulated radiotherapy technique, without chemotherapy, were accessed. DVC delineation was performed on MRI T1 sequences with gadolinium injection using a reference atlas. …”
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Oncolytic peptide LTX-315 induces anti-pancreatic cancer immunity by targeting the ATP11B-PD-L1 axis by Meng Wang, Xing Huang, Tingbo Liang, Tianyu Tang, Gang Zhang, Minghao Lu, Zhengtao Hong, Junming Huang, Xiao Zhi

“…Both in-house tissue microarray and open accessed The Cancer Genome Atlas data sets were used to evaluate the clinical relevance in pancreatic cancer prognosis.Results LTX-315 treatment inhibited PD-L1 expression and enhanced lymphocyte infiltration in pancreatic tumors. …”
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Effects of entinostat, quisinostat, and tubastatin-A on alcohol consumption in male high ethanol consuming rats by Sheketha R. Hauser, Sheketha R. Hauser, Laura B. Ferguson, Laura B. Ferguson, Tiebing Liang, Erin E. Jarvis, R. Dayne Mayfield, Richard L. Bell, Richard L. Bell

“…The objective of the current study was to test the effects of different HDACi on ethanol intake in two rat lines selectively bred for high ethanol-consumption.MethodAdult naïve male high alcohol drinking line 1 (HAD1) or alcohol-preferring (P) rats were given continuous 24-h, 3-bottle, free-choice access to 15%, 30% ethanol concurrently with water for 8 weeks prior to testing entinostat (selective HDAC1i and HADC3i, 0, 1.25, 2.5, 5 mg/kg, i. p.), quisinostat (pan HADCi, 0, 0.5, 1.0, 2.0 mg/kg, i. p.), or tubastatin-A (selective HDAC6i, 0, 1.25, 2.5, 5 mg/kg, i. p.) over 4-5 consecutive days.ResultsIn HAD1 rats, entinostat reduced 2-, 4-, and 24-h ethanol intake across the 2nd – 5th test days; while, in P rats, entinostat’s effect was primarily seen at the 24-h time-point, at the highest dose and only across three test days. …”
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Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves by A. A. Anashkina, E. N. Kuznetsov, A. V.  Batianovskii, L. A. Uroshlev, V. G. Tumanyan, N. G. Esipova

“…Totally, the interaction between protein atoms and nucleic base atoms accounts for 27.1 % of all contacts. Analysis of the accessible surface area of atoms in the major and the minor grooves showed a correlation with the number of contacts (coefficient of linear correlation 0.94 and 0.93, respectively), however, nucleic acid atoms forming hydrogen bonds make contacts more often than may be expected from statistical considerations. …”
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Characterizing Wellness Initiatives in Academic Radiation Oncology Departments by Sara Beltrán Ponce, MD, Crystal Seldon Taswell, MD, Idalid Franco, MD, MPH, Malcolm D. Mattes, MD, Tracy Kelly, MD, Leah Katz, MD, MPH

“…The most common previously implemented initiatives included offering programming and education (33.3%) and improved access to mental health services (25%). The most common active initiatives include conducting studies to address root causes of burnout (41.7%), developing specific wellness goals (25%), performing a review of policies that encourage prolonged work hours (25%), and offering programming and education (25%). …”
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How, why, where and when people feed birds?—Spatio‐temporal changes in bird‐feeding in Finland by Purabi Deshpande, Anna Haukka, Katja Rönkä, Tuomas Aivelo, Andrea Santangeli, Rose Thorogood, Aleksi Lehikoinen

“…In rural areas, people who reduced feeding more often identified concerns over avian diseases and the effort required to access, clean and refill bird‐feeding sites. Policy implications: Our results highlight that provisioning food to wild animals involves complex decision‐making depending on habitat, geography and economic factors. …”
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