Application of three-dimensional printing in the planning and execution of aortic aneurysm repair by Harshank Patel, Paul Choi, Jennifer C. Ku, Rosemary Vergara, Rafael Malgor, Dhiren Patel, Yong Li

“…This review examines the application of 3D printing and AI in complex aortic aneurysm repair, highlighting current clinical trends.MethodsAn exhaustive literature review was performed using keywords such as “3D printing,” “Artificial intelligence,” “Thoracoabdominal aneurysm,” “Abdominal aortic aneurysm,” “Aortic arch aneurysm,” “Endovascular repair,” and “Open repair” in PubMed and Google Scholar indexes up to June 2022.ResultsThis analysis included seven studies: four focused on 3D-printed phantoms for endovascular repair of various aortic pathologies (aortic arch, thoracoabdominal aorta, juxtarenal and pararenal aorta), one on open thoracoabdominal aneurysm repair using 3D-printed models for graft construction, and two on the use of convolutional neural networks, an AI-based technology, for the pre-processing of aortic computed tomography angiography images.ConclusionThe application of 3D printing and AI-based image pre-processing in the planning of complex aortic aneurysms offers several benefits, including enhanced patient and trainee education, more accurate fenestration placement, reduced surgical time and complications, and decreased surgeon stress.…”
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SP600125 Attenuates Nicotine-Related Aortic Aneurysm Formation by Inhibiting Matrix Metalloproteinase Production and CC Chemokine-Mediated Macrophage Migration by Zhen-Zhen Guo, Qun-An Cao, Zong-Zhuang Li, Li-Ping Liu, Zhi Zhang, Ya-Juan Zhu, Guang Chu, Qiu-Yan Dai

“…Nicotine, a major chemical component of cigarettes, plays a pivotal role in the development of abdominal aortic aneurysm (AAA). c-Jun N-terminal kinase (JNK) has been demonstrated to participate in elastase-induced AAA. …”
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Evaluation of Aneurysm Cases Undergoing Surgery at a Tertiary Center in Iran: A 22‐year Retrospective Study by Hamed Ghoddusi Johari, Keivan Ranjbar, Kimia Kassaee, Seyed Mohammadali Hoseini, Reza Shahriarirad

“…Specifically, an abdominal aortic aneurysm (AAA) is identified as an aortic diameter measuring at least one and a half times the standard diameter at the renal artery level, approximately equivalent to 2.0 cm. …”
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Hybrid Repair Combined with Fresh Arterial Allograft Extra-Anatomical Reconstruction: The Treatment of Infrarenal Abdominal Aneurysm above an Aortobifemoral Bypass Complicated by a... by Robert Novotny, Tomas Marada, Jiri Novotny, Jakub Kristek, Jaroslav Chlupac, Michal Kudla, Kvetoslav Lipar, Jiri Mendl, Jiri Fronek, Libor Janousek

“…Furthermore, the CTA revealed 11 cm juxtarenal abdominal aortic aneurysm (JAAA) from which the proximal anastomosis of the ABF was arising. …”
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Stimulation of Alpha7 Nicotinic Acetylcholine Receptor Attenuates Nicotine-Induced Upregulation of MMP, MCP-1, and RANTES through Modulating ERK1/2/AP-1 Signaling Pathway in RAW264... by Liping Liu, Hongxian Wu, Qunan Cao, Zhenzhen Guo, Anmin Ren, Qiuyan Dai

“…Treatment with α7-nAChR agonist inhibits nicotine-induced upregulation of MMP and inflammatory cytokines through modulating ERK1/2/AP-1 signaling in RAW264.7 cells and AP-1 in MOVAS cells, providing a new therapeutic for abdominal aortic aneurysm.…”
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The Accuracy of the NSQIP Universal Surgical Risk Calculator Compared to Operation-Specific Calculators by Mark E. Cohen, PhD, Yaoming Liu, PhD, Bruce L. Hall, MD, PhD, MBA, FACS, Clifford Y. Ko, MD, MS, MSHS, FACS

“…Operation-specific risk calculators (OS-RC) and OS-RCs with operation-specific predictors (OSP-RC) were independently developed for each of 6 operative groups (colectomy, whipple pancreatectomy, thyroidectomy, abdominal aortic aneurysm (open), hysterectomy/myomectomy, and total knee arthroplasty) and 14 outcomes using the same 80%/20% rule applied to the appropriate subsets of the 5M records. …”
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Design of a Cost-Effective Ultrasound Force Sensor and Force Control System for Robotic Extra-Body Ultrasound Imaging by Yixuan Zheng, Hongyuan Ning, Eason Rangarajan, Aban Merali, Adam Geale, Lukas Lindenroth, Zhouyang Xu, Weizhao Wang, Philipp Kruse, Steven Morris, Liang Ye, Xinyi Fu, Kawal Rhode, Richard James Housden

“…Validation was conducted using an ultrasound-compatible abdominal aortic aneurysm (AAA) phantom created from patient CT data and healthy volunteer testing. …”
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A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care dataResearch in context by Olivia Murrin, Ninon Mounier, Bethany Voller, Linus Tata, Carlos Gallego-Moll, Albert Roso-Llorach, Lucía A. Carrasco-Ribelles, Chris Fox, Louise M. Allan, Ruby M. Woodward, Xiaoran Liang, Jose M. Valderas, Sara M. Khalid, Frank Dudbridge, Sally E. Lamb, Mary Mancini, Leon Farmer, Kate Boddy, Jack Bowden, David Melzer, Timothy M. Frayling, Jane A.H. Masoli, Luke C. Pilling, Concepción Violán, João Delgado

“…Discordance between genetic and primary care data was also observed, e.g., abdominal aortic aneurysm and bladder cancer co-occurred in primary care but were not genetically correlated (Odds-Ratio = 2.23 [2.09:2.37], Rg = 0.04 [−0.20:0.28]) and schizophrenia and fibromyalgia were less likely to co-occur together in primary care but were positively genetically correlated (OR = 0.84 [0.75:0.94], Rg = 0.20 [0.11:0.29]). …”
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Stability of Membrane Elastodynamics with Applications to Cylindrical Aneurysms by A. Samuelson, P. Seshaiyer

“…The enlargement and rupture of intracranial and abdominal aortic aneurysms constitutes a major medical problem. …”
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Aortic Disease in the Young: Genetic Aneurysm Syndromes, Connective Tissue Disorders, and Familial Aortic Aneurysms and Dissections by Marcelo Cury, Fernanda Zeidan, Armando C. Lobato

“…In the absence of familial history and other clinical findings, the proportion of thoracic and abdominal aortic aneurysms and dissections resulting from a genetic predisposition is still unknown. …”
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Current Evidence and Insights about Genetics in Thoracic Aorta Disease by Gianluigi Bisleri, Lorenzo Bagozzi, Claudio Muneretto

“…Thoracic aortic aneurysms have been historically considered to be caused by etiologic factors similar to those implied in abdominal aortic aneurysms. However, during the past decade, there has been increasing evidence that almost 20% of thoracic aortic aneurysms may be associated with a genetic disease, often within a syndromic or familial disorder. …”
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Intraoperative rescue of a dislodged renal stent during fenestrated endovascular aortic repair for treatment of type 1A endoleak by Mario D’Oria, MD, Filippo Griselli, MD, Cristiano Calvagna, MD, Sandro Lepidi, MD

“…In the past 15 years, fenestrated-branched endovascular aortic repair (F-BEVAR) has progressively become the first-line option for management of most complex abdominal aortic aneurysms (AAAs); with increasing experience, as well as persistent technological refinements, F-BEVAR indications have been expanded to include rescue of failures after prior EVAR. …”
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Effect of Antrodia camphorata on Inflammatory Arterial Thrombosis-Mediated Platelet Activation: The Pivotal Role of Protein Kinase C by Wan-Jung Lu, Shih-Chang Lin, Chang-Chou Lan, Tzu-Yin Lee, Chih-Hsuan Hsia, Yung-Kai Huang, Hsiu-Chuan Lee, Joen-Rong Sheu

“…Critical vascular inflammation leads to vascular dysfunction and cardiovascular diseases, including abdominal aortic aneurysms, hypertension, and atherosclerosis. …”
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Hydrogen sulfide attenuates disturbed flow-induced vascular remodeling by inhibiting LDHB-mediated autophagic flux by Xia Wang, Xiying Huang, Yongya Zhang, Huanhuan Huo, Guo Zhou, Linghong Shen, Long Li, Ben He

“…Notably, the expression of LDHB was found to be elevated in vascular tissues from patients with abdominal aortic aneurysms (AAA) and thoracic aortic aneurysms (TAA). …”
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