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    Tigulixostat Alleviates Hyperuricemic Nephropathy by Promoting M2 Macrophage Polarization by Xue L, Tao Q, Chang H, Yan S, Wang L, Zhao Z, Tu C

    Published 2025-01-01
    “…Lina Xue,1,2,* Qianru Tao,1,2,* Haining Chang,1,* Shu Yan,1 Lei Wang,3 Zefang Zhao,4 Chao Tu1 1Department of Internal Medicine, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, People’s Republic of China; 2Department of Nephrology, The Third Affiliated Hospital of Soochow University, Changzhou, Jiangsu, People’s Republic of China; 3Nanjing jinyu medical examination laboratory, Nanjing, Jiangsu, People’s Republic of China; 4Hongyi Honor College, Wuhan University, Wuhan, Hubei, People’s Republic of China*These authors contributed equally to this workCorrespondence: Chao Tu, Department of Internal Medicine, The Third Affiliated Hospital of Soochow University, 185 Juqian Road, Changzhou, Jiangsu, 213000, People’s Republic of China, Tel +86 15895073069, Email tcmedical21@czfph.comPurpose: Serum uric acid (SUA) is primarily produced through the hydrolysis of purines in the liver, with its excretion largely handled by the kidneys. …”
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