Hospice Care by Suzanna Smith

“…“Recently a friend’s mother, Alice, was diagnosed with lung cancer, and even though she received all the possible treatments, the cancer was incurable. She went into hospice care so that she could get professional help in preparing herself and her family for her death.” …”
Get full text

Live-cell metabolic analyzer protocol for measuring glucose and lactate metabolic changes in human cells by Kenji Miki, Mikako Yagi, Ko Igami, Hiroki Kittaka, Akito Tani, Natsuki Horiuchi, Satoshi Fukumoto, Koji Yoshimoto, Takeshi Uchiumi

“…Summary: Understanding metabolic conditions related to glycolysis dependence is crucial for developing new treatments in cancer and regenerative medicine. This protocol details a method for using the live-cell metabolic analyzer (LiCellMo) to measure continuous changes in glucose consumption and lactate production in cultured human cells. …”
Get full text

Crosstalk between Gut Microbiota and Cancer Immunotherapy: Present Investigations and Future Perspective by Yuhui Tang, Qiaoting Cai, Zhi Tian, Wenkuan Chen, Hailin Tang

“…To better grasp the underlying crosstalk between gut microbiota and immunotherapy, more experimental and clinical trials are indispensable for the customized gut microbiota-based treatments in cancer patients undergoing immunotherapy.…”
Get full text

The known unknowns of the Hsp90 chaperone by Laura-Marie Silbermann, Benjamin Vermeer, Sonja Schmid, Katarzyna Tych

“…After decades of research, several ‘known unknowns’ about the molecular function of Hsp90 remain unanswered, hampering rational drug design for the treatment of cancers, neurodegenerative, and other diseases. …”
Get full text

Cancer Stem Cells and Their Microenvironment: Biology and Therapeutic Implications by Eunice Yuen-Ting Lau, Nicole Pui-Yu Ho, Terence Kin-Wah Lee

“…With a better understanding of how CSC interacts with its niche, we are able to identify potential therapeutic targets for the development of more effective treatments against cancer.…”
Get full text

Revolutionizing ovarian cancer therapy by drug repositioning for accelerated and cost-effective treatments by Edgar Yebran Villegas-Vazquez, Francisco Pável Marín-Carrasco, Octavio Daniel Reyes-Hernández, Andrea S. Báez-González, Lilia Patricia Bustamante-Montes, Teresita Padilla-Benavides, Laura Itzel Quintas-Granados, Gabriela Figueroa-González

“…These insights not only shed light on the efficacy of these drugs but also expand in potential synergies with other pharmaceutical agents, favoring the development of cost-effective treatments for cancer patients.…”
Get full text

Utilization of nanomaterials functionalized bio-field-effect transistors for detection of cancer biomarkers by Keerthana Madhivanan, Raji Atchudan, Sandeep Arya, Ashok K. Sundramoorthy

“…Despite of all the advanced treatments in cancer, the early detection and diagnosing the first stage of the disease is very important. …”
Get full text

Electrospun short fibers: a new platform for cancer nanomedicine applications by Yifan Huang, Mengsi Zhan, Mingwu Shen, Lili Zhang, Xiangyang Shi

“…Herein, this paper provides an overview of the recent advances in the design of electrospun short fibers that retain the advantages of nanofibers with good dispersibility for different nanomedicine applications, including cancer cell capture, cancer treatments, and cancer theranostics. The rational preparation of electrospun short fibers that are available to boost the development of nanomedicine is also discussed.…”
Get full text

Modulation of Nrf2 expression by targeting i-motif DNA by E. F. Warner, D. Guneri, M. A. O’Connell, C. J. MacDonald, Z. A. E. Waller

“…This is the first example of controlling the promoter of Nrf2 by targeting DNA structures and offers an alternative mode of action for the development of compounds to improve the chemotherapeutic responsiveness of existing treatments for cancer.…”
Get full text

On QSPR analysis of pulmonary cancer drugs using python-driven topological modeling by Huiling Qin, Mazhar Hussain, Muhammad Farhan Hanif, Muhammad Kamran Siddiqui, Zahid Hussain, Mohamed Abubakar Fiidow

“…This review sets the pace for establishing methodologies that are efficient in designing new and efficient treatments against cancer since it gives insight into the strengths and limitations of topological modeling. …”
Get full text

Current and Future Perspectives of PD-1/PDL-1 Blockade in Cancer Immunotherapy by Rangarirai Makuku, Neda Khalili, Sepideh Razi, Mahsa Keshavarz-Fathi, Nima Rezaei

“…Among immunotherapeutic agents, immune checkpoint inhibitors have been of particular interest and have gained approval by the FDA for treatment of cancers. Immune checkpoint blockade through targeting programmed cell death protein-1 (PD-1) has demonstrated promising antitumor effects in cancer immunotherapy of many different solid and hematologic malignancies. …”
Get full text

Strains, Mechanism, and Perspective: Salmonella-Based Cancer Therapy by Cheng-Zhi Wang, Robert A. Kazmierczak, Abraham Eisenstark

“…Furthermore, bacterial clinical treatments for cancer have been improved by combination with other therapeutic methods such as chemotherapeutic drugs and radioactive agents. …”
Get full text

Sorafenib-Associated Heart Failure Complicated by Cardiogenic Shock after Treatment of Advanced Stage Hepatocellular Carcinoma: A Clinical Case Discussion by Candace Wu, Kamal Shemisa

“…As TKI usage grows for treatment of cancers, heart failure-related complications will increase. …”
Get full text

Bibliometric and visual analysis of chronic stress in cancer research from 2014 to 2024 by Zhuheng Wei, Anxia Li, Ling Su, Bo Zhang, Yuanyuan Yan

“…The primary focus of the research is the impact of chronic stress on various cancer types, the underlying molecular mechanisms, and the implications of chronic stress-related treatments on cancer outcomes. Conclusion Chronic stress is increasingly recognized as a Carcinogenic factors. …”
Get full text

A Review on Colorectal Cancer and the Role of Traditional Chinese Herbal Medicine as Complementary Therapy by Jie Ji, Hiu Ching Phang, Xian Gu, Riyanto Teguh Widodo, Bey Hing Goh, Phei Er Kee, Siew-Keah Lee, Ashok Kumar Janakiraman, Long Chiau Ming, Kai Bin Liew

“…For many years, surgery and chemotherapy have been the mainstay treatments for cancer, but patients with metastatic disease have generally faced poor outcomes. …”
Get full text

Lactobacillus fermentum and Lactobacillus crispatus Do Not Have Cytotoxic Effects on HN5 Oral Squamous Cell Carcinoma Cell Line by Sepideh Mokhtari, Saede Atarbashi-Moghadam, Elahe Motevaseli, Soudeh Ghafouri-Fard, Ardeshir Hesampour

“…Lactobacilli are known as one of the newest methods for the prevention and treatment of cancers. Previous studies on the effects of probiotics on oral cancer cells are very limited, and only two species of Lactobacillus which are not present in the normal oral microflora have been studied. …”
Get full text

Synergistic Effects of Cabozantinib and EGFR-Specific CAR-NK-92 Cells in Renal Cell Carcinoma by Qing Zhang, Kang Tian, Jinjing Xu, Haixu Zhang, Liantao Li, Qiang Fu, Dafei Chai, Huizhong Li, Junnian Zheng

“…The chimeric antigen receptor-modified immune effector cell (CAR-T and CAR-NK) therapies are newly developed adoptive treatments of cancers. However, their therapeutic efficacy against solid tumors is limited. …”
Get full text

Exclusive Cutaneous and Subcutaneous Sarcoidal Granulomatous Inflammation due to Immune Checkpoint Inhibitors: Report of Two Cases with Unusual Manifestations and Review of the Lit... by Narciss Mobini, Rummit Dhillon, Jason Dickey, Jordan Spoon, Kaviyon Sadrolashrafi

“…Recent emergence of immune checkpoint inhibitors (ICIs) has revolutionized the treatment of cancers and produced prolonged response by boosting the immune system against tumor cells. …”
Get full text

Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy by Xiaopeng Li, Yang Zhong, Pengyuan Qi, Daoming Zhu, Chenglong Sun, Nan Wei, Yang Zhang, Zhanggui Wang

“…Radiotherapy (RT) is one of the most common treatments for cancer. However, intracellular glutathione (GSH) plays a key role in protecting cancer from radiation damage. …”
Get full text

Association of skin temperature, cumulative dose of radiation, and the diagnosis of radiodermatitis by Dryelle Soster Iede Shiguihara, Leandra Ulbricht, Eduardo Borba Neves

“… Radiotherapy is one of the treatments of cancer, and radiodermatitis is one of the side effects, with a negative impact on the patient's quality of life, which can lead to limitation dose of radiation, delay in completion, or discontinuation of treatment. …”
Get full text