Mesenchymal Stem Cell-Derived Extracellular Vesicles: Roles in Tumor Growth, Progression, and Drug Resistance by Xiaoyan Zhang, Huaijun Tu, Yazhi Yang, Lijun Fang, Qiong Wu, Jian Li

“…MSC-EVs open up a promising opportunity in the treatment of cancer with increased efficacy.…”
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Dosimetric Comparison of Tangential Volumetric Arc Therapy and Half Beam Volumetric Modulated Arc Therapy Planning Technique for Carcinoma of the Breast by Shreekripa Rao, Alpha Benny, Srinidhi Chandraguthi, Rechal Dsouza

“…Introduction: This study aims to compare tangential volumetric modulated arc therapy with half beam volumetric modulated arc therapy in the treatment of cancer in the left and right breasts. Material and Methods: Twenty patients (10 with left and 10 with right breast cancer) were planned with Tangential Volumetric Modulated Arc Therapy (tVMAT) and Half Beam Volumetric Modulated Arc Therapy (HVMAT) techniques for prescribed dose of 42.56Gy over 16 fractions with 6MV photon. …”
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Enhanced Morbidity of Pectoralis Major Myocutaneous Flap Used for Salvage after Previously Failed Oncological Treatment and Unsuccessful Reconstructive Head and Neck Surgery by Christiana Maria Ribeiro Salles Vanni, Leandro Luongo de Matos, Mário Paulo Faro Junior, Jossi Ledo Kanda, Cláudio Roberto Cernea, Lenine Garcia Brandão, Fábio Roberto Pinto

“…The reconstruction of complex cervicofacial defects arising from surgical treatment for cancer is a real challenge for head and neck surgeons, especially in salvage reconstruction surgery and/or failed previous reconstruction. …”
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Matrix metalloproteinase-3 is a potent prognostic factor associated with cell proliferation and migration in prostate cancer by Ai Sato, Kiyoshi Takagi, Mio Yamaguchi-Tanaka, Jotaro Okushima, Yuto Yamazaki, Akihiro Ito, Takashi Suzuki

“…Prostate cancer is a common malignancy in men around the world, and it is crucial to explore novel biomarkers to improve its treatment. Prostate cancer cells typically invade the surrounding stroma, and remodeling of the extracellular matrix (ECM) is a crucial step in the progress of prostate cancer. …”
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Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides by Serkan Yazıcı, Emel Bülbül Başkan, Ferah Budak, Barbaros Oral, Şaduman Balaban Adim, Zübeyde Ceylan Kalin, Güven Özkaya, Kenan Aydoğan, Hayriye Saricaoğlu, Şükran Tunali

“…TNMB and histopathological staging of the cases were retrospectively performed in accordance with International Society for Cutaneous Lymphomas/European Organization of Research and Treatment of Cancer (ISCL/EORTC) criteria at the time of flow cytometry sampling. …”
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Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines by Saidu I. Ngulde, Umar K. Sandabe, Roger Abounader, Ying Zhang, Isa M. Hussaini

“…Many of the plants claimed by the traditional medicine practitioners (TMPs) to be effective in the treatment of cancer are yet to be evaluated scientifically. …”
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Effects of a Multidisciplinary Educational Rehabilitative Intervention in Breast Cancer Survivors: The Role of Body Image on Quality of Life Outcomes by Giovanni Morone, Marco Iosa, Augusto Fusco, Antonella Scappaticci, Maria Rosaria Alcuri, Vincenzo Maria Saraceni, Stefano Paolucci, Teresa Paolucci

“…To assess the quality of life was administered The European Organization for Research and Treatment of Cancer Study Group on Quality of Life core questionnaire, while to investigate the psychological features and self-image were administered the following scales: the Body Image Scale, the Hamilton Rating Scale for Depression, and the State-Trait Anxiety Inventory. …”
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No impairment of quality of life after radiotherapy for prostate cancer by Maria M. Meier, Oliver Koelbl, Isabella Gruber

“…Health-related quality of life was assessed at a median of 63.6 months after radiotherapy using the European Organization for Research and Treatment of Cancer quality of life questionnaire (EORTC QLQ-C30) with 145 patients returning questionnaires (response rate, 58.7%). …”
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A Spiritual Care Program for Patients With Cancer and Psychosomatic Disorders in Iran: A Protocol Study by Rahmatollah Marzband, Seyed Hamzeh Hosseini, Zeinab Hamzehgardeshi, Mahmood Moosazadeh, Mohammad Eslamijouybari, Tahereh Yaghoubi, Marzieh Azizi, Fereshteh Araghian Mojarad, Ehsan Abedini

“…Background and Purpose: Considering that the treatment of cancer and psychosomatic diseases puts a high medical cost burden on the health system, it is necessary to use suitable services to improve the effectiveness of the treatment and thus reduce the costs. …”
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Synergistic Stimulation with Different TLR7 Ligands Modulates Gene Expression Patterns in the Human Plasmacytoid Dendritic Cell Line CAL-1 by Tobias Hilbert, Folkert Steinhagen, Christina Weisheit, Georg Baumgarten, Andreas Hoeft, Sven Klaschik

“…TLR7 ligation in plasmacytoid dendritic cells is promising for the treatment of cancer, allergy, and infectious diseases; however, high doses of ligands are required. …”
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Thapsigargin Induces Apoptosis by Impairing Cytoskeleton Dynamics in Human Lung Adenocarcinoma Cells by Fei Wang, Da-zhong Liu, Hao Xu, Yi Li, Wei Wang, Bai-lu Liu, Lin-you Zhang

“…The present findings highlight important roles of calcium entry in cytoskeleton organization and apoptosis in human lung adenocarcinoma cells and will help to set a stage to the clinical treatment of cancer cell metastasis.…”
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A Randomized, Double-Blind, Placebo-Controlled Trial Protocol Using the Fuzhengxiaoliu Patch for the Management of Primary Liver Cancer Pain by Li S, Wang B, Deng J, Li H, Wu Y, Fang Y, Yan B, Chen Y

“…Traditional Chinese medicine (TCM) has rich clinical experience in the treatment of cancer pain. The Fuzhengxiaoliu patch (FZXLP) is a compound TCM with the effects of detoxification and pain relief and has shown great efficacy in the treatment of patients with liver cancer, but high-quality clinical research that provides research-based evidence is lacking. …”
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Endoprosthetic Reconstruction for a Displaced Atypical Femoral Fracture in a Cancer Patient with Poor Prognosis by Hironari Tamiya, Hiroki Hagizawa, Takaaki Nakai, Yoshinori Imura, Takaaki Tanaka, Kazuya Oshima, Toshikazu Ito, Norifumi Naka, Shigeyuki Kuratsu

“…On the other hand, intramedullary nailing for displaced atypical femoral fractures occasionally causes problems with regard to bone healing, resulting in long-term treatment. In cancer patients with poor prognosis who experience atypical femoral fractures, improvement in activities of daily living should be the priority. …”
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A system‐based intervention to reduce Black‐White disparities in the treatment of early stage lung cancer: A pragmatic trial at five cancer centers by Samuel Cykert, Eugenia Eng, Paul Walker, Matthew A. Manning, Linda B. Robertson, Rohan Arya, Nora S. Jones, Dwight E. Heron

“…For the retrospective baseline, crude treatment rates were 78% for White patients vs 69% for Black patients (P < 0.001); difference by race was confirmed by a model adjusted for age, treatment site, cancer stage, gender, comorbid illness, and income‐odds ratio (OR) 0.66 for Black patients (95% CI 0.51‐0.85, P = 0.001). …”
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Biological evaluation of novel 5-((1H-indol-3-yl) methyl)-2-(4-chlorobenzyl)-6-phenyl-imidazo[2,1-b][13,4]thiadiazole derivatives as novel BCL-2 specific inhibitors by Shivangi Sharma, Sadashivamurthy Shamanth, Humaira Siddiqua, Laijau Goyary, Kunigal S. Sagar, Susmita Kumari, Divya Sathees, Gudapureddy Radha, Bibha Choudhary, Sathees C. Raghavan, Kempegowda Mantelingu

“…We report several derivatives of Disarib and the identification of DSR 43 and 4-OCH3, as the most potent among them. Treatment of cancer cell lines with the Disarib derivatives, DSR 43 and 4-OCH3 led to the activation of the apoptotic pathway without generating any ROS or disrupting the mitochondrial membrane potential within the cells, leading to cell death. …”
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Statistical analysis plan for a pragmatic randomised controlled trial comparing enhanced acceptance and commitment therapy plus ( +) added to usual aftercare versus usual aftercare... by Clare Robinson, Trudie Chalder, Paul McCrone, Olivier Quintin, Evdoxia Gkaintatzi, Imran Khan, Stephanie J. C. Taylor, on behalf of the SURECAN GROUP

“…Abstract Background The aim of the SURECAN trial is to evaluate a person-centred intervention, based on Acceptance and Commitment Therapy (ACT Plus ( +)), for people who have completed treatment for cancer with curative intent, but are experiencing poor quality of life. …”
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Prevalence of lymphedema symptoms across cancer diagnoses and association with depression, pain interference and health-related quality of life by Gitte Sone Larsen, Christoffer Johansen, Annika von Heymann, Bolette Skjødt Rafn

“…Utilized questionnaires were the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, the Major Depression Inventory, and the Brief Pain Inventory. …”
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Research status and thinking on the application of moxibustion therapy in cancer patients undergoing chemotherapy (艾灸疗法在肿瘤化疗患者中的应用研究现状与思考)... by MEI Yuwei (梅雨薇), ZHANG Mi (张秘), Li Yingjie (李迎杰), WANG Xue (王雪), WANG Zhihao (王志豪)

“…Chemotherapy is a common treatment for cancer, but the impact of side effects on the quality of life of patients is also the main problem that needs attention. …”
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The promising role of nanopore sequencing in cancer diagnostics and treatment by Xinming Su, Qingyuan Lin, Bin Liu, Chuntao Zhou, Liuyi Lu, Zihao Lin, Jiahua Si, Yuemin Ding, Shiwei Duan

“…In essence, this technology stands poised to unearth novel mechanisms underlying tumorigenesis while providing dependable support for the diagnosis and treatment of cancer.…”
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Real-world evaluation of physiotherapist-led exercise prehabilitation and rehabilitation during autologous stem cell transplantation in myeloma: a single-centre experience by Orla McCourt, Joanne Land, Neil Rabin, Kwee Yong, Abi Fisher, Jonathan Sive, Charalampia Kyriakou, Michael K Luong, Alasdair Longden

“…Functional (6 min walk and timed sit-to-stand tests) and patient-reported outcome measures (European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire (EORTC-C30) and EuroQol EQ5D-5L were assessed at preharvest, preadmission and in the post-ASCT evaluation (day 100) clinic.Results Patients (n=46) with a diagnosis of multiple myeloma referred for ASCT following induction chemotherapy were assessed. …”
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