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15221
Spinorphin Molecules as Opportunities for Incorporation into Spinorphin@AuNPs Conjugate Systems for Potential Sustained Targeted Delivery to the Brain
Published 2025-01-01“…<b>Methods:</b> Zeta (ζ) potential, Fourier transformation infrared (FTIR) spectroscopy, circular dichroism (CD), scanning electron microscopy (SEM-EDS), transmission electron microscopy (TEM), and UV–Vis spectrophotometry were employed to elucidate the structure–activity correlations of the peptide@nano AuNP systems. …”
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15222
Immune Dysregulation and Cellular Composition in Lichen Sclerosus Revealed by Integrative Epigenetic Analysis with Cell Type Deconvolution
Published 2025-01-01“…Jianwei Wang,1,* Hailang Fan,2,* Zhengqing Bao,1 Guizhong Li,1 Lingyan Wang,1 Dake Zhang2 1Urology Department, Beijing Jishuitan Hospital, Capital Medical University, Beijing, 102200, People’s Republic of China; 2Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education; Key Laboratory of Innovation and Transformation of Advanced Medical Devices, Ministry of Industry and Information Technology; National Medical Innovation Platform for Industry-Education Integration in Advanced Medical Devices (Interdiscipline of Medicine and Engineering); School of Engineering Medicine, Beihang University, Beijing, 100191, People’s Republic of China*these authors contributed equally to the workCorrespondence: Lingyan Wang, Urology Department, Beijing Jishuitan Hospital, Capital Medical University, Beijing, People’s Republic of China, Email wang_lingyan@foxmail.com Dake Zhang, Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Engineering Medicine, Beihang University, Beijing, People’s Republic of China, Email dakezhang@buaa.edu.cnBackground: Lichen sclerosus (LS) is a chronic inflammatory disease affecting skin and mucosal tissues, particularly external genitalia, with a risk of cancer. …”
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15223
A bibliometric study on the impact of gut microbiota on the efficacy of immune checkpoint inhibitors in cancer patients: analysis of the top 100 cited articles
Published 2025-01-01“…BackgroundImmune checkpoint inhibitors (ICIs) have transformed oncological treatment by modulating immune responses against tumors. …”
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15224
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15225
A Scalable Approach to Internet of Things and Industrial Internet of Things Security: Evaluating Adaptive Self-Adjusting Memory K-Nearest Neighbor for Zero-Day Attack Detection
Published 2025-01-01“…The Internet of Things (IoT) and Industrial Internet of Things (IIoT) have drastically transformed industries by enhancing efficiency and flexibility but have also introduced substantial cybersecurity risks. …”
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15226
A machine learning approach for vocal fold segmentation and disorder classification based on ensemble method
Published 2024-06-01“…This study emphasizes the potential of machine learning to transform the medical field’s capacity to categorize VF and segment VF, providing clinicians with a vital instrument to mitigate the profound impact of the condition. …”
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15227
Multi-label text classification via secondary use of large clinical real-world data sets
Published 2024-11-01“…In comparison to the transformer-based architecture, we were levering the non-contextual model fastText, a convolutional neural network, a support vector machine and logistic regression for a comparative analysis of possible coding performance. …”
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15228
Carbonic Anhydrase IX Targeted Polyaspartamide fluorescent Probes for Tumor imaging
Published 2025-01-01“…These derivatives were also characterized by Fourier transform infrared spectroscopy, gel permeation chromatography, ultraviolet-visible spectroscopy, nuclear magnetic resonance spectroscopy and fluorescence assays. …”
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15229
An Experimental Study of Coal Gangue Pulverization for Slurry Making and a Field Test on Hulusu Coal Mine Overburden Grouting
Published 2025-01-01“…With reference to fly ash granules and their slurry characteristics that have been previously applied successfully, raw gangue was pulverized and transformed into a slurry. This experiment then investigated the fundamental characteristics of the gangue powder solids and slurry. …”
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15230
Mechanical Mechanism of Water Injection to Enhance the Stability of Soft Coal
Published 2021-01-01“…The cohesive force increases first and then decreases, while the angle of internal friction almost has no change. (4) After reasonable water injection, the shape of liquid bridge in coal body changes into capillary tube, and the liquid bridge force reaches the maximum value, which transforms from a highly unstable bulk to a stable continuum. …”
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15231
CONCEPTUALIZATION OF THE INTERNATIONAL COOPERATION IN THE FIELD OF SCIENCE AND TECHNOLOGY
Published 2019-01-01“…It strengthens globalization and interdependence, expands the number of actors in world politics by strengthening the capabilities of non-state actors, it transforms national sovereignty, and also leads to the emergence of new, high-tech challenges and threats to international and national security. …”
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15232
MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach
Published 2023-01-01“…Thus, we aimed to indicate signaling pathways, Gene Ontology terms, and prognostic markers mediating the malignant transformation of the normal oral tissue to OTSCC and BSCC. …”
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15233
Cyanide ion oxidation by catalytic effect of nickel ferrites activated carbon composites
Published 2021-04-01“…The catalyst that showed the greatest capacity for cyanide transformation was that obtained by the hydro-chemical pathway with oxalic acid, achieving efficiencies of 96.3% oxidation of cyanide ion. …”
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15234
Initiation and sustenance of small portion size consumption behavior in rural Appalachia, USA: Application of multi-theory model (MTM)
Published 2019-03-01“…Results: Stepwise multiple regression demonstrated that initiation of small portion size consumption was explained by participatory dialogue (advantages outweighing disadvantages), behavioral confidence, and changes in physical environment (R2 = 47.9%, P < 0.001) and continuation of behavior by emotional transformation and practices for change (R2 = 40.2%, P < 0.001). …”
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15235
Study on the nonlinear transition relationship between water resources consumption and economic development in Heilongjiang province based on system dynamics
Published 2025-02-01“…The findings provide valuable insights for accelerating the green transformation of Heilongjiang Province and fostering the economy's and water resources' outstanding development.…”
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15236
RELATIONSHIP BETWEEN NATIVE INTELLIGENCE (NI) AND ARTIFICIAL INTELLIGENCE (AI): AN OVERVIEW
Published 2024-03-01“…Western Ideologists tend to attribute Native Intelligence (NI) to Africans / third-word concepts, indistinctly fixed to value and belief that aided social cultural, religious, political economic, spiritual evolution, and ancient societies, However, the Emergence of Artificial intelligence (AI) being the capacity of a computer system or machine to mimic human cognitive such as learning and solving problems, through a computer system that uses mathematics and logic, to simulate the reasoning ability of man, through the process of learning from new information, and transforming such information into actions, by making decisions that has increasingly enhanced the quality of human life. …”
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15237
Analysis of Complex Transportation Network and Its Tourism Utilization Potential: A Case Study of Guizhou Expressways
Published 2020-01-01“…This study broadens the practical application of traffic network complexity research and provides a scientific basis for upgrading and transforming the Guizhou expressway transportation network as well as for developing composite tourism uses for expressway service areas.…”
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15238
Presenting two new methods for solving linear interval optimal control problems using the resilience approach of control signal
Published 2024-12-01“…In these methods, the given interval optimal control problem is transformed into a non-interval (deterministic) optimal control problem so that it is possible to use the optimal control theory to solve it. …”
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15239
Supply chain performance in the age of Industry 4.0
Published 2025-02-01“…It also offers guidance for policymakers in supporting digital transformation initiatives. Social implications: By highlighting the benefits of digital supply chain integration, the study contributes to broader societal goals of economic development and industrial competitiveness in emerging markets. …”
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15240
AI enabled, mobile soil pH classification with colorimetric paper sensors for sustainable agriculture.
Published 2025-01-01“…Using mobile technology for paper sensor readout could, in principle, enable the application of machine-learning models for transforming colorimetric data into threshold-based classes that represent chemical concentration. …”
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