Evaluating the effects of dietary glutamine on performance, carcass traits, blood biochemistry, and intestine morphology in laying quail by Ewa Tomaszewska, Kamil Drabik, Kornel Kasperek, Piotr Dobrowolski, Monika Hułas-Stasiak, Renata Pyz-Łukasik, Waldemar Paszkiewicz, Monika Ziomek, Janine Donaldson, Katarzyna Dobrowolska, Artur Burmaczuk, Justyna Batkowska, Marcin B. Arciszewski, Siemowit Muszyński

Get full text

Harnessing genomic and bioinformatic data to broaden understanding of leukaemia across continents by Gumelar Gugun, Ulfa Mia Maria, Amukti Danang Prasetyaning, Irham Lalu Muhammad, Yuliani Sapto, Adikusuma Wirawan, Khairi Sabiah, Darmawi Darmawi, Chong Rockie, Ates Ilker, Singh Dilpreet, Chavan Aditya Ashok

Get full text

Speciation of Potentially Carcinogenic Trace Nickel(II) Ion Levels in Human Saliva: A Sequential Metabolomics-Facilitated High-Field ¹H NMR Investigation by Kayleigh Hunwin, Georgina Page, Mark Edgar, Mohammed Bhogadia, Martin Grootveld

“…These provided valuable molecular information regarding the identities of Ni(II) complexes in human saliva, which is relevant to trace metal ion speciation and toxicology, the <i>in vivo</i> corrosion of NiC-MADPs, and the molecular fate of ingested Ni(II) ions in this biofluid. …”
Get full text

Targeting KRAS G12C and G12S mutations in lung cancer: In silico drug repurposing and antiproliferative assessment on A549 cells by Mansour S. Alturki, Nada Tawfeeq, Amal Alissa, Zahra Ahbail, Mohamed S. Gomaa, Abdulaziz H. Al Khzem, Thankhoe A. Rants'o, Mohammad J. Akbar, Waleed S. Alharbi, Bayan Y. Alshehri, Amjad N. Alotaibi, Fahad A. Almughem, Abdullah A. Alshehri

Get full text

Association between exposure to perfluoroalkyl and polyfluoroalkyl substances with estimated glomerular filtration rate: Mediating role of serum albumin by Hua Fang, Huajing Chang, Danjing Chen, Wenxin Qiu, Jiangwang Fang, Yunli Wu, Xian-E. Peng

“…Mediation analysis was performed to examine the mediating role of albumin. Comparative toxicology databases identified relevant genes for mechanistic exploration. …”
Get full text

The CYP4/20-HETE/GPR75 axis in the progression metabolic dysfunction-associated steatosis liver disease (MASLD) to chronic liver disease by James P. Hardwick, Byoung-Joon Song, Paul Rote, Charles Leahy, Yoon Kwang Lee, Alexandra Rudi Wolf, Danielle Diegisser, Victor Garcia

Get full text

Analysis of acute non-pharmaceutical toxic exposures in children: a 5-year retrospective study by Yanning Qu, Rui Tang, Zhuyan Duan, Mengyi Sheng, Hui Wang, Shuang Liu, Jiao Li, Linlin Guo, Linying Guo, Si Zheng, Si Zheng

“…Logistic regression analysis showed that corrosive household products exposure (OR = 42.747, 95% CI[5.041–362.520]), skin and mucosal damage (OR = 37.052, 95% CI[5.339–257.153]), pesticides exposure (OR = 33.322, 95% CI[3.863–287.423]), heavy metals exposure (OR = 31.636, 95% CI[1.471–680.210]), neurological manifestation (OR = 22.656, 95% CI[4.766–107.711]), positive toxicology results (OR = 15.105, 95% CI[6.584–34.656]), industrial products exposure (OR = 10.294, 95% CI[1.144–92.641]), and intentional poisoning (OR = 3.060, 95% CI[1.733–5.405]) associated with hospitalization.ConclusionPediatric patients exposed to some specific toxicants like industrial products and corrosive household products might associated with a higher risk of severe clinical outcomes. …”
Get full text

Chromosome-level genome assembly and annotation of the gynogenetic large-scale loach (Paramisgurnus dabryanus) by Lei Zhang, Wanting Zhang, Yingyin Cheng, Yutong Fang, Xin Guan, Ao Gong, Yanxin Jiang, You Duan, Lei Huang, Waqar Younas, Yaping Wang, Mijuan Shi, Xiao-Qin Xia

“…Currently, molecular mechanism studies related to some aspects such as sex determination, toxicology, feed nutrition, growth and genetic evolution have been conducted. …”
Get full text

Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment by Annabelle M Belcher, Thomas O Cole, Aaron D Greenblatt, Stephen W Hoag, David H Epstein, Michael Wagner, Amy S Billing, Ebonie Massey, Kristen R Hamilton, Zofia K Kozak, Christopher J Welsh, Eric Weintraub, Emerson M Wickwire, Eric D Wish, Ted J Kaptchuk, Luana Colloca

“…Secondary outcomes include self-report of drug use; 3-month urine toxicology screen results; and treatment retention. …”
Get full text

Megagrazer loss drives complex landscape-scale biophysical cascades by Olli Hyvarinen, Mariska te Beest, Elizabeth le Roux, Graham I H Kerley, Robert Buitenwerf, Dave J Druce, Jiquan Chen, Linda Rapp, Joana Fernandes, Joris P G M Cromsigt

Get full text

Immunomodulatory and growth-promoting effects of Rauwolfia serpentina root powder in broiler chicks challenged with Salmonella Gallinarum by Yingyu Zhang, Hiba Rehman, Farina Khattak, Maryam Tariq, Bushra Nisar Khan, Sadia Chaman, Ayaesha Riaz, Muhammad Ovais Omer, Aqib Ali, Qamar un Nisa, Muhammad Muddassir Ali, Gulbeena Saleem

Get full text

Establishment of a Novel Model for Anticancer Drug Resistance in Three-Dimensional Primary Culture of Tumor Microenvironment by Tatsuya Usui, Masashi Sakurai, Shuhei Enjoji, Hideyoshi Kawasaki, Koji Umata, Takashi Ohama, Nobuyuki Fujiwara, Ryotaro Yabe, Shunya Tsuji, Hideyuki Yamawaki, Shoichi Hazama, Hiroko Takenouchi, Masao Nakajima, Ryouichi Tsunedomi, Nobuaki Suzuki, Hiroaki Nagano, Koichi Sato

Get full text

How resistant is anammox biofilm against antibiotics: A special insight into anammox response towards fluoroquinolones by Faysal-Al Mamun, Rohit Kumar, Kelvin Ugochukwu Anwuta, Sovik Das, Madis Jaagura, Koit Herodes, Tetyana Kyrpel, Agnieszka Fiszka Borzyszkowska, Anna Zielińska-Jurek, Zane Vincevica-Gaile, Juris Burlakovs, Andrey E. Krauklis, Mohamad Nor Azra, Md Salauddin, Jiexi Zhong, Taavo Tenno, Kai Bester, Ivar Zekker

Get full text

Association between PM2.5 components and poor ovarian response in assisted reproductive technology patients: A retrospective cohort study identifying sensitive exposure windows in... by Rui-Ling Liu, Zhi-Lei Xu, Yu-Ling Hu, Xing-Yu Lv, Quan-Zi Yao, Jia-Liang He, Li-Juan Fu, Li-Hong Geng, Tong Wang, Zhao-Hui Zhong, Yi-Jian Zhu, Yu-Bin Ding

Get full text

Comparative transcriptome analysis reveals molecular mechanisms of resistance in Chinese cabbage to Plasmodiophora brassicae pathotype 11 by Yue Qiu, Yue Qiu, Yue Qiu, Jinhao Zhang, Jinhao Zhang, Chunju Deng, Chunju Deng, Jiasheng Yuan, Jiasheng Yuan, Bowen Wang, Bowen Wang, Han Meng, Han Meng, Mohamed Mohany, Liting Zeng, Liting Zeng, Lanfang Wei, Lanfang Wei, Waqar Ahmed, Guanghai Ji, Guanghai Ji

Get full text

Edible mushrooms as a potent therapeutics of subclinical thyroid dysfunction among adults, especially in obese individuals: a prospective cohort study by Juanjuan Zhang, Sabina Rayamajhi, Amrish Thapa, Ge Meng, Qing Zhang, Li Liu, Hongmei Wu, Yeqing Gu, Shunming Zhang, Tingjing Zhang, Xuena Wang, Zhixia Cao, Jun Dong, Xiaoxi Zheng, Xu Zhang, Xinrong Dong, Xing Wang, Shaomei Sun, Ming Zhou, Qiyu Jia, Kun Song, Kaijun Niu

Get full text

Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae by Chenkai Ge, Zhijun Ye, Weitao Hu, Jingrong Tang, Huimin Li, Fasheng Liu, Xinjun Liao, Jianjun Chen, Shouhua Zhang, Zigang Cao

“…This study expands our understanding of the potential effects of the pesticide pyrazosulfuron-ethyl on injured fish, highlights the link between the immune system and the regeneration process, and demonstrates the potential application of fin regeneration in risk assessments of environmental toxicology to assess drug toxicity.…”
Get full text

CD40-TRAF6 inhibition suppresses cardiovascular inflammation, oxidative stress and functional complications in a mouse model of arterial hypertension by Lea Strohm, Henning Ubbens, Dominika Mihalikova, Alexander Czarnowski, Paul Stamm, Michael Molitor, Stefanie Finger, Matthias Oelze, Dorothee Atzler, Philip Wenzel, Philipp Lurz, Thomas Münzel, Christian Weber, Esther Lutgens, Andreas Daiber, Steffen Daub

Get full text

State of Lung Cancer in Egypt: Moving Towards Improved Guidelines for Prevention, Screening, Treatment, and Clinical Care Programs by Nagla Abdel Karim, MD, Ahmed Magdy Rabea, MD, Philip C. Mack, PhD, Janakiraman Subramanian, MD, Ehab Khalil, MD, Mai Sherif, MD, Radwa Marawan, MD, Tagrid Gaafar, MD, Lobna Shash, MD, Kei Suzuki, MD, Manmeet Ahluwalia, MD, Hisham Wahba, MD, Salma Aboelela, MSc, Asrar Al Ahmadi, MD, Hamed Al Husaini, MD, Nada Mohsen, MD, Rana Khaled, MD, Neemat Kassem, MD, Hussein Khaled, MD, Noha El Said, MD, Nadia Zakhary, MD, Dina Shoukry, MD, Alaa Abdullah ElSadieque, MSc, M. Yasser Alsedfy, MSc, Shaheen Islam, MD, Hend ElSherbiny, MD, Mervat El Deftar, MD, Noha Awad, MD, Abdel Rahman Mohamed, MD, David Gandara, MD, Karen Kelly, MD, Triparna Sen, PhD

Get full text

Modulation effects of folic acid and vitamin D on the relationships between prenatal cumulative phthalate exposure and preschoolers’ emotional and behavioral problems by Li-wen Chen, Xin Chen, Chen Han, Bei-bei Zhu, Yi-fan Wang, Yuan Liu, Min-min Jiang, Ya-fei Wang, Chun-han Shan, Hua-yan Mo, Kun Huang, Hui Gao, Fang-biao Tao

Get full text