The potential therapeutic role of berberine in treating epilepsy focusing on temporal lobe epilepsy: State of art and ongoing perspective by Bshra A. Alsfouk, Hayder M. Al-Kuraishy, Ali K. Albuhadily, Ali I. Al-Gareeb, Ahmed M. Abdelaziz, Athanasios Alexiou, Marios Papadakis, Mubarak Alruwaili, Gaber El-Saber Batiha

Get full text

The ameliorative effect of selenium-loaded chitosan nanoparticles against silver nanoparticles-induced ovarian toxicity in female albino rats by Omnia E. Shalaby, Yasmine H. Ahmed, Aya M. Mekkawy, Mohamed Y. Mahmoud, G. A. Elbargeesy

Get full text

Active Antialopecia Chemical Identification of Merremia peltata Leaves and Computational Study toward Androgen Receptor Using Molecular Docking and Molecular Dynamic Simulation by Syawal Abdurrahman, Ruslin Ruslin, Aliya N. Hasanah, Resmi Mustarichie, Mus Ifaya

“…An in silico study was then carried out using minoxidil as a comparison ligand; 17 compounds derived from M. peltata leaves were identified as antialopecia compounds through prediction of molecular interactions and molecular dynamics simulation and prediction of absorption, distribution, metabolism, excretion, and toxicology (ADME-Tox). The assay results showed that fractions F2 and F3 had a better effect on hair growth compared to the positive control, and the test compound obtained from the LC-MS analysis, bufotalinin, had a strong binding energy to the receptor in the molecular docking interaction study: −5.99 kcal/mol compared to −4.8 kcal/mol for minoxidil. …”
Get full text

Synergistic anticancer effects of cisplatin and phenolic aglycones of the aerial part of Rumex dentatus L. in tongue squamous cell carcinoma: insights from network pharmacology and... by Amany E. Ragab, Ghada M. Al-Ashmawy, Sherin R. El Afify, Ola A. El-Feky, Amera O. Ibrahim

Get full text

Drug consumption and treatment costs of the glaucoma therapy in the Republic of Serbia by Ćoškov Aleksandra D., Savanović Dijana R., Todorović Nemanja B., Lalić-Popović Mladena N., Tomić Nataša Z., Milijašević Boris Ž.

Get full text

Psychological Safety in Saudi Arabian Healthcare: A Scoping Review by Yumna Ali, Roaya Alqurashi, Ahmed M. Asfahani, Mark Leonard, Catherine Elisa John, Yasuhiro Kotera

Get full text

Syzygium cumini fresh juice ameliorated memory impairment in a scopolamine-induced amnesic mouse model through active avoidance paradigm by Nosheen Malik, Hammad Murtaza, Waseem Ashraf, Muhammad Fawad Rasool, Farhan Siddique, Maryam Bashir, Tanveer Ahmad, Faleh Alqahtani, Imran Imran

Get full text

An insight into the therapeutic impact of quinoxaline derivatives: Recent advances in biological activities (2020–2024) by Aly M. Waseem, Ranya Mohammed Elmagzoub, Mervat Mohammed Mazhar Abdelgadir, Areej Al Bahir, N.S. Abd EL-Gawaad, Ahmed S. Abdel-Samea, Devendra Pratap Rao, Konstantinos Kossenas, Stefan Bräse, Hamada Hashem

Get full text

Prevalence of Ticks Infesting Dairy Cattle and the Pathogens They Harbour in Smallholder Farms in Peri-Urban Areas of Nairobi, Kenya by Shepelo Getrude Peter, Hellen Wambui Kariuki, Gabriel Oluga Aboge, Daniel Waweru Gakuya, Ndichu Maingi, Charles Matiku Mulei

Get full text

Predictors of oral anticoagulant-associated adverse events in seniors transitioning from hospital to home: a retrospective cohort study protocol by Lehana Thabane, James Douketis, Anne Holbrook, Gary Foster, Harsukh Benipal, J. Michael Paterson

Get full text

Trace metals induce microbial risk and antimicrobial resistance in biofilm in drinking water by Bowei Li, Ling Feng, Rakia Chouari, Sofia Samoili, Stefanos Giannakis

Get full text

Carboxymethyl cellulose/shellac composite loaded with pomegranate extract and jojoba oil as anti-mycotic and anti-mycotoxigenic food packaging materials by Salah A. A. Mohamed, Amr Farouk, Adel G. Abdel-Razek, El-Shahat Nashy, Mohamed El-Sakhawy, Ahmed Noah Badr

Get full text

Particulate matter concentrations and health risks associated with cow hides singeing in Abattoirs in Benin City, Nigeria by Aimuanmwosa Frank Eghomwanre, Gracious Oghosa Edomwonyi

Get full text

Association of direct oral anticoagulant-proton pump inhibitor cotherapy with adverse outcomes: protocol for a population-based cohort study by Lehana Thabane, Lawrence Mbuagbaw, Michael Paterson, Laura Targownik, Mei Wang, Anne Holbrook, Deborah Siegal

Get full text

Corrigendum to “Inhibition of HIF-2α expression in cardiomyocytes attenuates PCB126-induced cardiotoxicity associated with decreased apoptosis through the PI3K/Akt and p53 signalin... by Long Chen, Li-Jian Chen, Hong-Wu Shen, Clare Hsu, Jia-Hao Zeng, Jia-Hao Li, Jia-Li Liu, Jian-Zheng Yang, Yi Liu, Xiu-Wen Li, Xiao-Li Xie, Qi Wang, Dong Zhao

Get full text

Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways by Li Jia, Kuijin Xue, Junheng Liu, Ola A. Habotta, Lianhai Hu, Ahmed E. Abdel Moneim

Get full text

The Predictive Role of Parathyroid Hormone for Nonalcoholic Fatty Liver Disease following Bariatric Surgery by Tannaz Jamialahmadi, Mohsen Nematy, Mohammed Abdalla, Ali Jangjoo, Ladan Goshayeshi, Matthew Kroh, Seyed Adel Moallem, Mitra Abbasifard, Thozhukat Sathyapalan, Amirhossein Sahebkar

Get full text

From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents by Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse, Hamada Hashem

Get full text

Evaluation of Antimicrobial Activity and Cytotoxicity of an Epoxy Resin-Based Endodontic Sealer Containing Nanoparticles Amorphous Calcium Phosphate by Bilal H. Ibrahim, Hussain Al-Huwaizi

“…The cytotoxicity of the NACP incorporated AH Plus and AH Plus sealers were tested indirectly by MTT assay and directly by the multiparametric high content screening toxicology assay using fibroblast-like cells as cell lines. …”
Get full text

Computational antidiabetic assessment of Salvia splendens L. polyphenols: SMOTE, ADME, ProTox, docking, and molecular dynamic studies by Hatun A. Alomar, Wafaa M. El Kady, Asmaa A. Mandour, Amany A. Naim, Neveen I. Ghali, Taghreed A. Ibrahim, Noha Fathallah

Get full text