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1901
Effect of Paraquat on Tilapia Fingerlings under laboratory condition
Published 2019-08-01“…Mortality was measured at different time intervals of 10hr, 12hr, 16hr, 20hr, 46hr and 52hr for the range finding test, using different concentrations of paraquat (120mg/l, 60mgl, 30mg/l and 15mg/l). Acute toxicity test, using different concentrations of paraquat (10mg/l, 5mgl, 2.5mg/l and 1mg/l) was used to measure mortality of 4, 0, 0 and 0 respectively, for 96hrs. …”
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1902
In vitro antioxidant capacity and free radical scavenging evaluation of standardized extract of Costus afer leaf
Published 2018-12-01“…Keywords: Costus afer, Antioxidant, Toxicity…”
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1903
Massive Acetaminophen Overdose Treated Successfully with N-Acetylcysteine, Fomepizole, and Hemodialysis
Published 2021-01-01“…There is strong evidence for N-acetylcysteine (NAC) as a safe and effective antidote for acetaminophen toxicity. However, there is less clarity in the management of massive overdoses (acute, single ingestions>500 mg/kg with 4-hour equivalent concentrations ~6000 μmol/L) which are often associated with metabolic acidosis and multiorgan dysfunction. …”
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1904
Co(II) Complex of Mefloquine Hydrochloride: Synthesis, Antimicrobial Potential, Antimalaria and Toxicological Activities
Published 2012-01-01“…Overall, it was revealed that both mefloquine and its metal complex do not showed toxicity particularly on the liver and kidney.…”
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1905
Stable and inert manganese complexes for magnetic resonance imaging
Published 2024-02-01“…Manganese is an essential metal which alleviates its potential toxicity and the environmental concerns related to the use of Gd$^{3+}$. …”
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1906
Ethylene Glycol Poisoning: An Unusual Cause of Altered Mental Status and the Lessons Learned from Management of the Disease in the Acute Setting
Published 2016-01-01“…Ethylene glycol is found in many household products and is a common toxic ingestion. Acute ingestions present with altered sensorium and an osmolal gap. …”
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1907
Heavy Metal Stress and Some Mechanisms of Plant Defense Response
Published 2015-01-01“…Unprecedented bioaccumulation and biomagnification of heavy metals (HMs) in the environment have become a dilemma for all living organisms including plants. HMs at toxic levels have the capability to interact with several vital cellular biomolecules such as nuclear proteins and DNA, leading to excessive augmentation of reactive oxygen species (ROS). …”
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1908
Recycling of Oily Sludge as a Roadbed Material Utilizing Phosphogypsum-Based Cementitious Materials
Published 2019-01-01“…The efficacy of the S/S process is assessed mainly through an unconfined compressive strength (UCS) test and a toxicity leaching test. Road performance, including water stability, freeze-thaw resistance, and volume stability, is also tested on the solidified samples. …”
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1909
Nanoparticles Modulating the Immune Microenvironment in Breast Cancer Treatment
Published 2025-02-01“…The review addresses the challenges in clinical translation, focusing on safety, biocompatibility, and toxicity. Finally, we outline future research directions and the potential advancements in nanoparticle-based immunotherapy, emphasizing their transformative impact on breast cancer treatment.Keywords: nanoparticle, breast cancer, immune cells…”
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1910
Natural products as part of triple negative breast cancer
Published 2025-01-01“…Immunotherapy causes a wide variety of toxic effects called immune-related adverse events (IRAEs). …”
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1911
Decolorization of mixture of dyes: A critical review
Published 2015-01-01“…These effluents are recalcitrant to biodegradation and cause acute toxicity to the receiving water bodies, as these comprised of various types of toxic dyes, which are difficult to remove. …”
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1912
Optimization of Green Synthesis of Selenium Nanoparticles and Evaluation of Their Antifungal Activity against Oral Candida albicans Infection
Published 2022-01-01“…Increasing resistance of microbes to available antimicrobial agents has necessitated the production of new compounds with wider activity and lower toxicity. Candida is one of the pathogenic fungal strains that are highly prevalent in oral diseases. …”
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1913
Resolution of Crizotinib-Associated Fulminant Hepatitis following Cessation of Treatment
Published 2018-01-01“…Targeted cancer treatments offer the prospect of precise inhibition of tumor growth without the untoward off-target toxicity of traditional chemotherapies. Still, unintended, often idiosyncratic side effects, such as drug-induced liver injury, can occur. …”
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1914
Site-Specific Immunosuppression in Vascularized Composite Allotransplantation: Prospects and Potential
Published 2013-01-01“…Investigating the site-specific therapeutic effects and efficacy of systemically active agents may enable optimizing the dosing, frequency, and duration of overall immunosuppression in VCA with minimization or elimination of long-term drug-related toxicity.…”
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1915
Impact Evaluation of Wastewater Treatment Based on the Anaerobic Digestion of Sewage Sludge Using the Life Cycle Assessment Method
Published 2024-01-01“…Among the 18 effect classes, the treated wastewater in the class of marine environmental toxicity with the amount of 101.1531 kg 1,4-DCB had the most environmental impacts among other classes. …”
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1916
Revolution of blood cancer treatment in the oral cavity: Breakthroughs in nanotherapy
Published 2024-09-01“…Nanoparticles (NPs) made from organic and inorganic materials have shown promise in delivering therapeutic substances to cancer cells, enhancing their pharmacological efficacy, and reducing their systemic toxicity. Different types of nanoparticles, such as liposomes, extracellular vehicles, and polymeric nanoparticles, have been studied for their effectiveness in targeting cancer cells. …”
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1917
Evaluating the effectiveness of propylene glycol and ethanol as antifreeze: an environmentally friendly alternative
Published 2025-01-01“…Moreover, some environmental concerns and toxicity risks are associated with the use of such oil. …”
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1918
The evolution of antifungal therapy: Traditional agents, current challenges and future perspectives
Published 2025-01-01“…The current arsenal of antifungal drugs is limited and often accompanied by high toxicity to patients, elevated treatment costs, increased frequency of resistance rates, and the emergence of naturally resistant species. …”
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1919
Effect of Paraquat on Tilapia Fingerlings under laboratory condition
Published 2019-08-01“…Mortality was measured at different time intervals of 10hr, 12hr, 16hr, 20hr, 46hr and 52hr for the range finding test, using different concentrations of paraquat (120mg/l, 60mgl, 30mg/l and 15mg/l). Acute toxicity test, using different concentrations of paraquat (10mg/l, 5mgl, 2.5mg/l and 1mg/l) was used to measure mortality of 4, 0, 0 and 0 respectively, for 96hrs. …”
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1920
GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth
Published 2024-12-01“…The construct’s pharmacokinetics (PK), toxicity profile, and in vivo efficacy were also evaluated.Results GrB-Fc-KS49 exhibited comparable GrB enzymatic activity to commercial GrB, as well as high affinity to an EMP2 peptide, with the dissociation constant in the picomolar range. …”
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