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1801
A Case of Acute Motor Sensory Axonal Neuropathy: A Variant of Guillain-Barré Syndrome, with Possible Syndrome of Irreversible Lithium-Effectuated Neurotoxicity
Published 2020-01-01“…We present a unique case of a 38-year-old female patient with decade-long use of lithium for bipolar disorder that presented with acute lithium toxicity. Though she was ultimately diagnosed with AMSAN, the Syndrome of Irreversible Lithium-Effectuated Neurotoxicity (SILENT) may have also contributed to her persistent neurological sequelae.…”
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1802
A Case of Chronic Calcific Nonalcoholic Pancreatitis
Published 2016-01-01“…The etiology of TCP remains uncertain, with the current consensus suggesting genetics as well as possible toxicity from consuming large amounts of cassava, a tuber. …”
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1803
Recycling of plastic waste polyethylene terephthalate (PET) as a modifier in asphalt mixture: study of Creep-Recovery at Low, Medium, and Hot Temperatures
Published 2022-04-01“…., These plastics become a problem because of their non-biodegradability, toxicity, etc. The recovery of plastic waste in pavements has become an ecological technique that contributes to the preservation of natural resources. …”
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1804
Studies on Dyeing Performance of Novel Acid Azo Dyes and Mordent Acid Azo Dyes Based on 2,4-Dihydroxybenzophenone
Published 2009-01-01“…Results of bactericidal studies of chrome pretreated fibers revealed that the toxicity of mordented dyes against bacteria is fairly good. …”
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1805
Functionalized Selenium Nanoparticles Enhance Anticancer Efficacy of Doxorubicin for Hepatocellular Carcinoma Therapy
Published 2022-01-01“…To address this dilemma, tumor-targeted nanotechnology has been proposed to balance the toxicity and efficacy of chemotherapy. Tumor-targeted selenium nanoparticles (HA-SeNPs) were prepared to load an anticancer drug doxorubicin (DOX). …”
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1806
FK228 Analogues Induce Fetal Hemoglobin in Human Erythroid Progenitors
Published 2012-01-01“…To determine the physiological relevance of these compounds, studies in primary erythroid progenitors confirmed that JMA26 and JMA33 activated HbF synthesis at levels comparable to FK228 with low cellular toxicity. These data support our lead compounds as potential therapeutic agents for further development in the treatment of SCD.…”
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1807
Determining application rates of FYM and pressmud to improve soil health properties in salt degraded soils.
Published 2025-01-01“…The findings of this study suggested that organic amendments can improve soil fertility, mitigate salt ion toxicity, and enhance food production potential, particularly in arid and semi-arid soils.…”
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1808
From detection to elimination: iron-based nanomaterials driving tumor imaging and advanced therapies
Published 2025-02-01“…Regarding treatment, INMs play a key role in advanced strategies such as immunotherapy, magnetic hyperthermia, and synergistic combination therapy, which effectively overcome tumor-induced drug resistance and reduce systemic toxicity. The integration of INMs with artificial intelligence (AI) and radiomics further expands its capabilities for precise tumor identification, and treatment optimization, and amplifies treatment monitoring. …”
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1809
Discriminating Analysis of Metal Ions via Multivariate Curve Resolution–Alternating Least Squares Applied to Silver Nanoparticle Sensor
Published 2025-01-01“…Heavy metals are life-threatening pollutions because of their great toxicity, long-term persistence in nature and their bioaccumulation in living organisms. …”
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1810
Targeting Apoptosis Pathways in Cancer with Alantolactone and Isoalantolactone
Published 2013-01-01“…Inula japonica, Aucklandia lappa, Inula racemosa, and Radix inulae, have been found to have various pharmacological actions including anti-inflammatory, antimicrobial, and anticancer properties, with no significant toxicity. Recently, the anticancer activity of alantolactone and isoalantolactone has been extensively investigated. …”
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1811
Analysis of Hepatic Artery Infusion (HAI) Chemotherapy Using Randomized Trials of Floxuridine (FUDR) for Colon Cancer Patients with Multiple Liver Metastases
Published 2022-01-01“…The parameters like toxicity, overall survival rate, response rate, and progression-free response for the suggested therapy are also analyzed. …”
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1812
Prediction of hemolytic peptides and their hemolytic concentration
Published 2025-02-01“…Abstract Peptide-based drugs often fail in clinical trials due to their toxicity or hemolytic activity against red blood cells (RBCs). …”
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1813
Phytosynthesis of Titanium Dioxide Nanoparticles Using King of Bitter Andrographis paniculata and Its Embryonic Toxicology Evaluation and Biomedical Potential
Published 2021-01-01“…The phytosynthesis TiO2 shows the antioxidant and antidiabetic activities. Similarly, toxicity studies have demonstrated the hatching and viability LD 50 value of TiO2 250 μg/L. …”
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1814
Exploring effector protein dynamics and natural fungicidal potential in rice blast pathogen Magnaporthe oryzae.
Published 2025-01-01“…Additionally, the compounds were evaluated based on Lipinski's rule of five and toxicity predictions, indicating their suitability for agricultural use. …”
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1815
Current Status of Plant-Based Bioactive Compounds as Therapeutics in Alzheimer’s Diseases
Published 2025-01-01“…The pathogenesis of AD remains unclear and current Western medicines treatment are purely symptomatic, with a singular pathway, limited efficacy, and substantial toxicity and side effects. In recent years, as research into AD has deepened, there has been a gradual increase in the exploration and application of medicinal plants for the treatment of AD. …”
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1816
Rising incidence of recreational ketamine use: Clinical cases and management in emergency settings
Published 2025-06-01“…This trend has been accompanied by an increase in first aid incidents involving ketamine, often in combination with other substances such as alcohol or MDMA, leading to heightened toxicity. Acute intoxication with ketamine manifests through symptoms like agitation, hallucinations, nausea, tachycardia, and hypertension, while frequent use is associated with long-term complications, including ketamine-induced uropathy. …”
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1817
Intravenous γ Globulin for Intractable Abdominal Pain due to IgA Vasculitis
Published 2020-01-01“…We present two children with IgA vasculitis and severe abdominal pain despite corticosteroid administration, who responded promptly to intravenous γ globulin (IVIg) with complete resolution of their symptoms and review of the relevant medical literature. Given the toxicity and/or need for long-term administration of other second-line immunosuppressive therapies in corticosteroid-resistant IgA vasculitis, such as rituximab, cyclosporine, cyclophosphamide, azathioprine, or colchicine, we propose that IVIg may be a useful and safe treatment option, although randomized controlled clinical trials are needed in order to clarify its role in the treatment of abdominal pain in IgA vasculitis.…”
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1818
Severe Rhabdomyolysis Associated with Simvastatin and Role of Ciprofloxacin and Amlodipine Coadministration
Published 2015-01-01“…Simvastatin is among the most commonly used prescription medications for cholesterol reduction and the most common statin-related adverse drug reaction is skeletal muscle toxicity. Multiple factors have been shown to influence simvastatin-induced myopathy. …”
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1819
Expanding Yarrowia lipolytica’s metabolic potential for detoxification of cyanogenic glycosides in edible plants
Published 2025-02-01“…Abstract Cyanides are highly toxic chemicals in several edible plants that threaten food safety and human health. …”
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1820
Effect of Local Anesthesia with and without the Vasoconstrictor on Blood Glycemic Level in Diabetic Patients Undergoing Tooth Extractions
Published 2024-12-01“…Background: Vasoconstrictors with local anesthetics provide a bloodless as well as toxicity-free area for effortless extraction tooth. …”
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