A Survey of Mycotoxin Contamination in Fermented Condiments and the Biological Methods for Its Reduction by WANG Lihui, FU Jinhui, LI Chaowei, ZHANG Li, XIA Xiaolong, LI Sitong, ZHANG Mengmei, CHEN Yinzhu, LIU Shuliang, HU Kaidi, ZHAO Ning, LI Qin, LI Jianlong

“…Microorganisms can convert mycotoxins into low-toxicity or non-toxic substances through the adsorption of cell walls or enzymatic catalysis, thus ensuring the safety of fermented condiments for consumption. …”
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Analysis of HIV therapy in the liver using optimal control and pharmacokinetics by Hasifa Nampala, Matylda Jabłońska-Sabuka, Martin Singull

“…An objective function is defined with an aim to investigate the optimal control strategy that minimises toxicity, viral load and cost of first-line and second-line HIV regimen. …”
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Synergistic Effects of SDS and H2O2 Combinations on Tracheal Scaffold Development: An In Vitro Study Using Goat Trachea by Dhihintia Jiwangga, Ferdiansyah Mahyudin, Gondo Mastutik, Estya Nadya Meitavany, null Juliana, Priangga Adi Wiratama

“…The results demonstrated that the combination of SDS and H2O2 for goat tracheal decellularization yielded scaffolds with minimal cellular remnants, low toxicity, preserved ECM, and high tensile strength and elasticity. …”
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Quantitative and Qualitative Analysis of Aconitum Alkaloids in Raw and Processed Chuanwu and Caowu by HPLC in Combination with Automated Analytical System and ESI/MS/MS by Aimin Sun, Bo Gao, Xueqing Ding, Chi-Ming Huang, Paul Pui-Hay But

“…Furthermore, HA was little hydrolyzed by heating processes and thus it might account more for the toxicity of processed aconites. Hence, HA could be used as an indicator when one alkaloid is required as a reference to monitor the quality of raw and processed Chuanwu and Caowu. …”
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Attention-based deep learning for accurate cell image analysis by Xiangrui Gao, Fan Zhang, Xueyu Guo, Mengcheng Yao, Xiaoxiao Wang, Dong Chen, Genwei Zhang, Xiaodong Wang, Lipeng Lai

“…In comparative tests on drug-induced cardiotoxicity, mitochondrial toxicity classification, and compound classification, X-Profiler outperformed both DeepProfiler and CellProfiler, as two highly recognized and representative methods in this field. …”
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Intravitreal Ampicillin Sodium for Antibiotic-Resistant Endophthalmitis: Streptococcus uberis First Human Intraocular Infection Report by Raul Velez-Montoya, Dulce Rascón-Vargas, William F. Mieler, Jans Fromow-Guerra, Virgilio Morales-Cantón

“…While treatment with intravitreal ampicillin is feasible, there are still concerns about its possible toxicity.…”
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Nanomédicaments pour le traitement de maladies graves et recherches duales by Couvreur, Patrick

“…By releasing the active ingredient at the level of pathological cells and tissues, these nanocarriers help reduce toxicity while improving therapeutic efficacy. They also protect fragile molecules from rapid metabolization and can promote their intracellular penetration. …”
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St-N, a novel alkaline derivative of stevioside, reverses docetaxel resistance by targeting lysosomes in vitro and in vivo. by Yanxia Guo, Shikang Wang, Qun Liu, Yan Dong, Yongqing Liu

“…In docetaxel-resistant PCa homograft mice, St-N significantly inhibited the growth of RM-1/Doc homografts and enhanced the anticancer effects of docetaxel, but did not show significant toxicity. Taken together, these findings demonstrated that St-N reversed docetaxel resistance in vitro and in vivo by destabilizing lysosomal membranes to promote cell death, thus providing a strong rationale for applying St-N in docetaxel-resistant PCa.…”
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Theoretical Investigation on the Solubilization in Water of Functionalized Single-Wall Carbon Nanotubes by Michael Mananghaya, Emmanuel Rodulfo, Gil Nonato Santos, Al Rey Villagracia

“…This should lower the toxicity of nanotubes and improve their biocompatibility.…”
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Rifampicin in Nontuberculous Mycobacterial Infections: Acute Kidney Injury with Hemoglobin Casts by Rishi Kora, Sergey V. Brodsky, Tibor Nadasdy, Dean Agra, Anjali A. Satoskar

“…Rifampicin is a key component of multidrug regimens not only for tuberculosis, but also nontuberculous mycobacterial infections (NTM) which are on the rise worldwide. Knowledge of the toxicity profile is important. Hepatotoxicity is a well-known side effect of Rifampicin necessitating regular liver function monitoring during therapy. …”
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Cross-platform hatedom: Influencers’ strategies for managing affective aversion by Arantxa Vizcaíno-Verdú, Paloma Contreras-Pulido

“… Amidst the rise of toxic behavior in online fan communities, this study examines the construction of cross-platform hatedom through social media and the strategies influencers use to navigate hostile digital environments. …”
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Prevalence of Pharmaceuticals in Surface Water Samples in Ghana by David Azanu, David Adu-Poku, Selina Ama Saah, William Ofori Appaw

“…Pharmaceuticals, among the emerging contaminants, are pseudopersistent and recently of serious concern due to universal use, toxicity, and resistance development at low concentrations. …”
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Myoglobin Cast Nephropathy Diagnosed on Renal Biopsy in a Patient Treated for Malarial Infection by Ramya Varadarajan, Ashmi Patel, Haneen Salah, Neil Sutaria, Roberto Barrios, Luan Truong, Lillian Gaber, Ziad M. El-Zaatari

“…Previous literature has suggested mechanisms for the development of rhabdomyolysis in malarial infection, including inflammatory processes, direct effect of parasite accumulation, and drug-induced toxicity. Our case further implicates antimalarial therapy as a cause of rhabdomyolysis and increases awareness of myoglobin cast nephropathy as a potential complication of malaria.…”
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Ibrutinib-associated osteonecrosis of the jaw by Annu Singh, Sion Na, Joseph M. Huryn, Cherry L. Estilo, Steven Horwitz, SaeHee K. Yom

“…Ibrutinib has well-described side effects that limits its use such as, increased risk of atrial fibrillation, hypertension, and hemorrhage. However, oral toxicity associated with ibrutinib has not been reported. …”
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Chemical Profiling Ethyl Acetate Extract of <i>Basilicum polystachyon</i> Leaves and Exploration of Anticancer SIRT1 Inhibitors Using <i>In Silico</i> Approach by Tukiran Tukiran, Muhammad Raihan

“…Natural products are the primary source of medicinal compounds believed to have lower toxicity and side effects than synthetic drugs. This research aimed to reveal the chemical profile of the ethyl acetate extract of Basilicum polystachyon leaves. …”
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Reversion of Hormone Treatment Resistance with the Addition of an mTOR Inhibitor in Endometrial Stromal Sarcoma by J. Martin-Liberal, C. Benson, C. Messiou, C. Fisher, I. Judson

“…Response has been maintained for more than 2 years with minimal toxicity and treatment is ongoing. Conclusion. This case suggests that the resistance to the hormone manipulation in ESS can be reversed by the addition of an mTOR pathway inhibitor. …”
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O istotnych kontrowersjach wokół oceny zagrożeń środowiska i jego naprawy by Konrad Gałuszko

“…Subsequently to the above were discussed: the criticism of some misconceptions and the evolution of scientists. opinions about derivations of the greenhouse effect, toxicity and carcinogenesis criteria, evidence supporting the threshold dose versus the linear hypothesis at the evaluation of harmful environmental effects, examples of ecological utopia assuming a possibility of “life in the world without toxins”, the consequences of acts of law created with the idea, untrustworthy examples of alleged hazards, Poland’s law delay with the assimilation of the new toxicological and carcinogenesis evidence, DDT application dilemma concerned with the latter, the acceptance of the threshold dose also for radioactivity, the latest news about ravages of the Chernobyl catastrophe, the author’s belief in better cooperation of humanists, ecophilosophers, scientists and mass media people to create sensible social attitudes of the public in the face of the ecological and civilization crisis.…”
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Facioscapulohumeral muscular dystrophy: a review of pathogenesis, clinical symptoms, and treatment by T. Mikalauskas, B. Burnytė

“…The phenotypic differences between the two types are not distinct, both resulting from dysregulation of DUX4 expression leading to skeletal muscle toxicity. The first type is characterised by a reduction in D4Z4 repeats, while the second type is characterised by mutations in genes encoding epigenetic regulators such as SMCHD1. …”
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Synthesis, Characterization, and Agricultural Biological Activities of 5-Fluoro-2-hydroxy Butyrophenone by Fengli Xin, Chunhua Du, Gongjia Lan, Zhuanping Wu

“…The target compound also shows potent herbicidal activities for Lactuca sativa, a dicotyledon, and Echinochloa crus-galli, a monocotyledon. The toxicity regression C50 values of the compound against Valsa mali, Coniothyrium diplodiella, Lactuca sativa seedling, and Echinochloa crusgalli seedling were calculated by SPSS. …”
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NIR-activated catechol-functionalized nanodiamond nanofibers for accelerating on-demand MRSA and E. coli biofilm eradication by Hyeonseo Park, Tejal V. Patil, Jieun Lee, Hojin Kim, Seong-Jun Cho, Ki-Taek Lim

“…Our research proposes a platform that not only effectively addresses antibiotic-resistant infections but also contributes to advancements in wound healing therapies by enabling controlled antibacterial action with minimal toxicity.…”
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