Effects of Metalloporphyrins on Heme Oxygenase-1 Transcription: Correlative Cell Culture Assays Guide in Vivo Imaging by Monica Hajdena-Dawson, Weisheng Zhang, Pamela R. Contag, Ronald J. Wong, Hendrik J. Vreman, David K. Stevenson, Christopher H. Contag

“…Furthermore, serum enzyme assays indicated that neither caused detectable liver toxicity. These findings, and especially those with ZnBG, support the use of selected Mps as therapies for pathologic jaundice. …”
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Hypolipidemic Effect of Chloroform Extract of Lagenaria siceraria: Potential Inhibitory Activity of Phytochemicals Targeting the HMG-CoA Reductase Revealed by Molecular Docking and... by Qudsia Kanwal, Mahmood Ahmed, Atiq Ur-Rehman, Aneela Anwar, Samiah Shahid, Atif Shahzad, Attaullah Shah Bukhari, Muhammad Ahmad, Numan Yousaf, Muhammad Muddassar

“…The experimental animals did not display any acute toxicity. Atorvastatin (10 mg/kg bw) was used as a standard drug. …”
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Microglial Lyzl4 Facilitates β‐Amyloid Clearance in Alzheimer's Disease by Jie Pan, Jie Zhong, Ji Geng, Jane Oberhauser, Shihua Shi, Jun Wan

“…Despite a wealth of research on the toxicity of Aβ and its role in synaptic damage, the mechanisms facilitating Aβ clearance are not yet fully understood. …”
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Environmental impact assessment of southern tehran wastewater treatment plant using life cycle assessment (LCA) by Zeinab Samsami, Ahmad Jonidi Jafari, Mohammad Delnavaz, Azra Naderi, Reza Barati Rashvanlou, Behnam Movassagh Inchehboroun, Emad Dehghanifard

“…Although the use of treated wastewater and digested sludge for agricultural land may save a significant amount of water, it has significant adverse effects on carcinogenic and noncarcinogenic toxicity in humans due to the presence of heavy metals and has a negative effect on global warming.…”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…All these disadvantages engender the need for new therapy. siRNA delivery carriers like liposomes, polymeric nanoparticles, and siRNA polymer bio-conjugates are proving to be particularly effective with less toxicity compared to the traditional treatments. A promising addition to these carriers is wrapsome (WS), which can be used as a favorable carrier for delivery of siRNA to its specific sites, such as inflamed joints or the inflamed synovium. …”
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A comprehensive in silico analysis of structural and functional impacts of natural nonsynonymous SNPs in the ALDH2_HUMAN gene by Mehr Ali Mahmood Janlou

“…Acetaldehyde exhibits a toxic effect, highlighting the necessity of ALDH2’s proper functioning to protect against diseases associated with aldehyde toxicity. …”
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Effect of 3-hydrazinylquinoxaline-2-thiol hydrogel on skin wound healing process in diabetic rats by Jehan Barakat Alamre, Huda Alkreathy, Ahmed S. Ali, Abdelbagi Alfadil, Sahar S. Alghamdi

“…In silico study indicated a favorable drug-like properties and toxicity profile. The present work showed that 3-hydrazinylquinoxaline-2-thiol holds great potential for the treatment of diabetic wounds.…”
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Protective Effects of Garlic and Cinnamon Oils on Hepatocellular Carcinoma in Albino Rats by Salah M. Aly, Hamdy A. Fetaih, Abeer A. I. Hassanin, Mosleh M. Abomughaid, Aliaa A. Ismail

“…The present findings proposed that these natural oils have the ability to improve liver function, significantly reduced the liver toxicity and HCC development. However, further sophisticated studies are recommended before their use as conventional therapeutics for HCC treatment.…”
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Sensitive and Simultaneous Determination of Hydroquinone and Catechol in Water Using an Anodized Glassy Carbon Electrode with Polymerized 2-(Phenylazo) Chromotropic Acid by Miao Zhang, Chuang-ye Ge, Ya-feng Jin, Liang-bin Hu, Hai-zhen Mo, Xiao-bo Li, Hao Zhang

“…Hydroquinone (HQ) and catechol (CT) are considered as environmental pollutants with high toxicity. We have developed a simple electrochemical sensor using an anodized glassy carbon electrode modified with a stable 2-(phenylazo) chromotropic acid- (CH-) conducting polymer (PCH/AGCE). …”
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Evaluation of the optical, structural, morphological and electronic properties of Rb3Bi2I9 Perovskites films prepared by Sequential Evaporation by G. Gordillo, O.G. Torres, C.A. Celis, M. Reinoso, J I Clavijo

“…Toxicity and poor stability remain major barriers to large-scale production of hybrid organic-inorganic lead halide perovskite solar cells. …”
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Life Cycle Assessment of Biofuel Production from Sugarcane Bagasse by Nasri Nurul Farhana, Mohd Hanafiah Marlia, Harun Siti Norliyana, Chong Jing Wen, Hassan Faez M.

“…The findings revealed that biofuel production from sugarcane significantly impacts terrestrial ecotoxicity (10.44 kg 1,4-DCB), human non-carcinogenic toxicity (2.61 kg 1,4-DCB), and global warming (2.60 kg CO2 eq). …”
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Lipid Horizons: Recent Advances and Future Prospects in LBDDS for Oral Administration of Antihypertensive Agents by null Preeti, Sharda Sambhakar, Rohit Malik, Saurabh Bhatia, Ahmed Al Harrasi, Renu Saharan, Geeta Aggarwal, Suresh Kumar, Renu Sehrawat, Chanchal Rani

“…The future of hypertension management using LBDDS is promising, with ongoing reviews focusing on precision medicine approaches, improved biocompatibility, and reduced toxicity. As we delve deeper into understanding the intricate mechanisms underlying hypertension, LBDDS offers a pathway to develop next-generation antihypertensive therapies that are safer, more effective, and tailored to individual patient needs.…”
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Polystyrene nanoplastics promote the blood-brain barrier dysfunction through autophagy pathway and excessive erythrophagocytosis by Eun-Hye Kim, Seung Mi Baek, Han Jin Park, Yiying Bian, Han Young Chung, Ok-Nam Bae

“…Our study will help to understand the cardiovascular toxicity of nano-sized plastics.…”
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Targeting Shp2 as a therapeutic strategy for neurodegenerative diseases by Jiao Pang, Changqian Cen, Yuan Tian, Xingrui Cao, Liang Hao, Xueshu Tao, Zhipeng Cao

“…Shp2 is closely related to NDs-related pathogenic factors such as oxidative stress, mitochondrial dysfunction, excitatory toxicity, immune inflammation, apoptosis, and autophagy. …”
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Effects and Impact of Selenium on Human Health, A Review by Song Bai, Miaohe Zhang, Shouying Tang, Miao Li, Rong Wu, Suran Wan, Lijun Chen, Xian Wei, Shuang Feng

“…Despite its critical importance to human health, the range between selenium’s nutritional and toxic doses is very narrow. Insufficient daily selenium intake can lead to selenium deficiency, while excessive intake carries the risk of selenium toxicity. …”
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Combustion Behaviour of ADN-Based Green Solid Propellant with Metal Additives: A Comprehensive Review and Discussion by Rushikesh Kore, Ashish Vashishtha

“…Ammonium dinitramide (ADN) has gained considerable attention as a potential oxidizer for green solid propellants due to its high oxygen content, significant energy density, non-toxicity, and non-polluting combustion products, leading to lower environmental impact. …”
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Effect of Short-Term Stress and Interaction of Salinity and Ammonia-N Levels, Associated With Food Deprivation on Fatty Acid Profile and Body Composition in Nile Tilapia (Oreochrom... by Eisa Ebrahimi, Javad Motamedi-Tehrani, Rahim Peyghan

“…High levels of nitrogen compounds can lead to acute toxicity in aquatic organisms. Ammonia, a by-product of protein breakdown, is the most prevalent contaminant in freshwater environments. …”
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Cystatin C-Based Equations Detect Hidden Kidney Disease and Poor Prognosis in Newly Diagnosed Patients with Multiple Myeloma by Francisco-Javier Cepeda-Piorno, Esther González-García, Alba Méndez-Gallego, Juan Torres-Varona, Vanesa García-Moreira, Christian Sordo-Bahamonde, Cristina AlberdiGarcía-del-Castillo, Elene Astobieta-Madariaga, Maria-Victoria Mateos-Manteca, Segundo González-Rodríguez

“…The IMWG criteria may underestimate kidney disease, mostly in women, which could affect the dose received as well as its toxicity. Altogether, our data suggest that equations that include CysC are more accurate to detect hidden kidney disease, as well as patients with more and worse prognostic factors, in newly diagnosed MM.…”
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Experimental Research on Mechanical Property and Environmental Safety of an Industrial Residue Waste Subgrade Material by Yangpeng Zhang, Jianping Xiong, Qinglin Li, Jiuhui Cui

“…Furthermore, the chemical stability and toxicity of SOF leachates are environmentally friendly, which are in line with the benchmarks of Class II surface water and Class III ground water. …”
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MoS₂–Plasmonic Hybrid Platforms: Next-Generation Tools for Biological Applications by Nayra A. M. Moussa, Seungah Lee, Seong Ho Kang

“…Despite the promising advancements of MoS₂–plasmonic hybrids, translating these platforms into clinical practice requires overcoming considerable challenges, such as synthesis reproducibility, toxicity, stability in physiological conditions, targeted delivery, and scalable manufacturing. …”
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