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2021
RETRACTED ARTICLE: Novel magnetic organic–inorganic hybrids based on aromatic polyamides and ZnFe2O4 nanoparticles with biological activity
Published 2021-10-01“…So, the prepared hybrid is biocompatible and non-toxic to Hu02 cells. Also, it has antibacterial ability against gram-positive and gram-negative bacteria. …”
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2022
Targeting epithelial-mesenchymal transition signaling pathways with Dietary Phytocompounds and repurposed drug combinations for overcoming drug resistance in various cancers
Published 2025-02-01“…This review also investigates the concept of low-toxicity and broad spectrum (“The Halifax Project”) approach which can help for site targeting of several key pathways and their mechanism. …”
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2023
Phosphate-sensing mechanisms and functions of phosphate as a first messenger
Published 2024-04-01“…Several of these responses to phosphate are considered as phosphate toxicity. However, it is not clear whether FGFR1 is involved in these responses to phosphate. …”
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2024
17α-Ethynyl-5α-androstane-3α, 17β-diol Treatment of MNU-Induced Mammary Cancer in Rats
Published 2011-01-01“…The combination of HE3235 with docetaxel was more effective than any single agent, although without apparent toxicity. Only HE3235 or HE3235 plus docetaxel continued to suppress tumor growth after cessation of treatment. …”
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2025
Chemical composition and insecticidal efficacy of two animals’ horn and hoof crude extracts against lesser grains borer, Rhyzopertha dominica (F.) [Coleoptera: Bostrichidae]
Published 2025-01-01“…Different concentrations (0.1, 0.2, 0.3, 0.4 and 0.5 ml) of the crude extracts were applied per 20 g of wheat grains to assess the toxicity effect on adult mortality and adult emergence. …”
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2026
RETRACTED ARTICLE: Histological, ultrastructural, and biochemical study on the possible role of Panax ginseng in ameliorating liver injury induced by Lambda cyhalotherin
Published 2020-12-01“…Although claiming that LCT has a low mammalian toxicity, several investigations reported its mammalian hepatotoxicity by mediating oxidative stress causes severe hepatotoxicity and liver damage. …”
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2027
Scutellarin combined with lidocaine exerts antineoplastic effect in human glioma associated with repression of epidermal growth factor receptor signaling.
Published 2025-01-01“…Additionally, SCU and lidocaine also inhibited the growth of glioma in vivo, and the effect of the combination was better. Above all, the toxicity of SCU and its combination with lidocaine was low to normal astrocytes and neurons. …”
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2028
Deciphering CSU pathogenesis: Network toxicologyand molecular dynamics of DOTP exposure
Published 2025-02-01“…Conclusion: This study clarifies the potential molecular mechanisms of DOTP-induced CSU and underscores the efficacy of network toxicology, molecular docking, and molecular dynamics simulations in assessing the toxicity of food and environmental pollutants and their related molecular biological mechanisms. …”
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2029
Quand des pesticides empoisonnent la recherche, la réglementation et la démocratie :
Published 2021-05-01“…Without losing sight of the essential points, Seralini and Douzelet expose the agrochemical giant’s tremendous power to manipulate information to conceal Roundup’s toxicity, but above all, the extent of its strategies to subvert the very foundations of public regulations intended to protect health and the environment. …”
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2030
Evaluation of hesperidin as a potential larvicide against Culex pipiens with computational prediction of its mode of action via molecular docking
Published 2025-01-01“…However, further research is needed to assess its toxicity to non-target organisms and optimize its formulation for broader application in mosquito control.…”
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2031
A Review on Biosurfactant Applications in the Petroleum Industry
Published 2021-01-01“…They are biotechnological products of high value owing to their widespread applications, low toxicity, relatively easy preparation, and specific performance, applied in different industries like organic chemicals and fertilizers, agrochemicals, metallurgy and mining, cosmetics, foods, medical and pharmaceuticals, beverages, environmental management, and petroleum and petrochemical applications in emulsifying and demulsifying wetting agents, detergent spreading and foaming agents, and functional food ingredients. …”
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2032
Microbial Control in the Processing of Low-Temperature Meat Products: Non-Thermal Sterilization and Natural Antimicrobials
Published 2025-01-01“…Biocides are extensively used in the antibacterial field owing to their high efficiency, low toxicity, and long-lasting properties. Both non-thermal sterilization technology and biocides can ensure food safety, extend the shelf life of food products, improve food quality, meet consumers’ demand for natural and healthy food, enhance market competitiveness, and play a positive role in promoting the sustainable development of the food industry. …”
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2033
Natural compounds in the management of polycystic ovary syndrome: a comprehensive review of hormonal regulation and therapeutic potential
Published 2025-02-01“…Recently, natural compounds have garnered considerable attention due to their efficacy in hormone modulation and minimal toxicity. Substances such as myo-inositol, resveratrol, berberine, and quercetin have shown promise in mitigating PCOS symptoms. …”
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2034
Biological Character of RetroNectin Activated Cytokine-Induced Killer Cells
Published 2016-01-01“…Median survival time (mOS) after first R-CIK cell infusion was 10.57 months; the 1-year survival rate was 38.5%. No serious toxicity was associated with R-CIK cell infusion. In conclusion, RetroNectin may enhance antitumor activity of CIK cells: it is safe for use in treating pancreatic cancer.…”
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2035
Isolation and Structural Identification of New Diol Esters of Okadaic Acid and Dinophysistoxin-1 from the Cultured <i>Prorocentrum lima</i>
Published 2025-01-01“…All diol esters exhibited cytotoxic effects, with compound <b>3</b> displaying toxicity comparable to OA. These results expand our understanding of DSP toxin diversity and provide valuable insight into the structural variations and biological activity of diol esters of OA/DTX-1.…”
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2036
Safety Profile and Effects of Pulsed Methylprednisolone on Vital Signs in Thyroid Eye Disease
Published 2015-01-01“…No significant cardiovascular or hepatic toxicity was found. Conclusion. IVMP is relatively safe and efficacious. …”
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2037
Lithium as an Alternative Option in Graves Thyrotoxicosis
Published 2015-01-01“…There were no signs of lithium toxicity within this time period. Conclusion. Lithium has a unique physiologic profile and can be used to treat thyrotoxicosis when thionamides cannot be used while awaiting elective radioablation. …”
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2038
New Approach Methodologies: Physiological responses of daphnids to pharmaceutical mixtures
Published 2025-11-01“…The pharmaceutical cocktail comprised of representatives of commonly encountered pharmaceuticals and specifically diclofenac, metformin, gabapentin, amoxicillin, trimethoprim, and erythromycin. Combining toxicity, phenotypic and molecular endpoints, results showed differences in mortality, feeding, key enzyme activities and metabolic perturbations, thus supporting a distinct pattern in physiological responses of daphnids that could be used to monitor and predict pollution early.…”
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2039
Interesting Cytokine Profile Caused by Clinical Strains of Pseudomonas aeruginosa MDR Carrying the exoU Gene
Published 2024-01-01“…In addition, PBMC exposed to strains of four different categories according to their resistance and toxicity showed a differential pattern of cytokine expression, a decrease in IL-10, IL-6, and IL-8, and an over-secretion of IL-1b. …”
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2040
Novel cisplatin-magnetoliposome complex shows enhanced antitumor activity via Hyperthermia
Published 2025-02-01“…The ML has no significant toxicity both in vitro and in vivo and, most importantly, enhances cell death by apoptosis after magnetic hyperthermia. …”
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