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Systematic surveillance of SARS-CoV-2 reveals dynamics of variant mutagenesis and transmission in a large urban population
Published 2024-12-01“…We previously described C19-SPAR-Seq, a high-throughput, next-generation sequencing platform to detect SARS-CoV-2 that we here deployed to systematically profile variant dynamics of SARS-CoV-2 for over 3 years in a large, North American urban environment (Toronto, Canada). Sequencing of the ACE2 receptor binding motif and polybasic furin cleavage site of the Spike gene in over 70,000 patients revealed that population sweeps of canonical variants of concern (VOCs) occurred in repeating wavelets. …”
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Impact of interventions on mpox transmission during the 2022 outbreak in Canada: a mathematical modeling study of three different cities
Published 2025-04-01“…Methods: We estimated changes in sexual behaviors during the outbreak using 2022 data from the Engage Cohort Study, which recruited self-identified GBM in Montréal, Toronto, and Vancouver (n = 1,445). We developed a transmission dynamic model to estimate the fraction of new infections averted due to the three interventions in each city. …”
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Whipple’s Endocarditis: An Enigmatic Cause of Culture-Negative Bacterial Endocarditis
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Electrical Nerve Stimulation Can Be Used as a Tool in fMRI Studies of Pain- and Tingling-Evoked Activations
Published 2000-01-01Get full text
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Time to Make the Change from ‘Primary Biliary Cirrhosis’ to ‘Primary Biliary Cholangitis’
Published 2015-01-01Get full text
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Combination of Ciprofloxacin and Metronidazole in Severe Perianal Crohn’s Disease
Published 1993-01-01Get full text
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West Nile Virus Infection in the Intensive Care Unit: A Case Series and Literature Review
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Hepatitis B Learning Needs Assessment of Family Medicine Trainees in Canada: Results of a Nationwide Survey
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Oversized cells activate global proteasome-mediated protein degradation to maintain cell size homeostasis
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