ATG8 delipidation is not universally critical for autophagy in plants by Yong Zou, Jonas A. Ohlsson, Sanjana Holla, Igor Sabljić, Jia Xuan Leong, Florentine Ballhaus, Melanie Krebs, Karin Schumacher, Panagiotis N. Moschou, Simon Stael, Suayib Üstün, Yasin Dagdas, Peter V. Bozhkov, Elena A. Minina

“…Remarkably, the more complex autophagy machinery of Arabidopsis renders ATG8 delipidation entirely dispensable for the maturation of autophagosomes, autophagic flux, and related stress tolerance; whereas autophagy in Chlamydomonas strictly depends on the ATG4-mediated delipidation of ATG8. …”
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Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought by Douglas Jardim-Messeder, Ygor de Souza-Vieira, Gilberto Sachetto-Martins

“…This review provides an overview of the intricate relationship between ROS, redox metabolism, and the nine different phytohormones signaling in plants, shedding light on potential strategies for enhancing drought tolerance for sustainable crop production.…”
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Comparison of Predicted Exercise Capacity Equations and the Effect of Actual versus Ideal Body Weight among Subjects Undergoing Cardiopulmonary Exercise Testing by H. Reza Ahmadian, Joseph J. Sclafani, Ethan E. Emmons, Michael J. Morris, Kenneth M. Leclerc, Ahmad M. Slim

“…This is a retrospective chart review of patients who were predominantly in active military duty with complaints of dyspnea or exercise tolerance and who underwent cardiopulmonary exercise testing (CPET) from 2007 to 2009. …”
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Immunotherapy for Hepatocellular Carcinoma: Current Advances and Future Expectations by Yingjun Xie, Yien Xiang, Jiyao Sheng, Dan Zhang, Xiaoxiao Yao, Yongsheng Yang, Xuewen Zhang

“…In recent years, tumor immunotherapy has emerged as a promising method owing to its safety and efficacy with respect to delaying the progression of advanced tumors and protecting postoperative patients against tumor relapse and metastasis. Immune tolerance and suppression in tumor microenvironments are the theoretical basis of immunotherapy. …”
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Integration research of blockchain and social networks in rural management systems under fuzzy cognitive environment by Wencun Wang, Jun Yao, Di Zhao, Can Huang

“…Subsequently, by incorporating fuzzy set theory and adopting an enhanced blockchain consensus algorithm—the Byzantine Fault Tolerance (BFT) algorithm— a comprehensive rural management system is established, combining fuzzy sets and blockchain. …”
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B7-H4 Pathway in Islet Transplantation and β-Cell Replacement Therapies by Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock

“…B7-H4 protects allograft survival and generates donor-specific tolerance. It also prevents the development of autoimmune diabetes. …”
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Factors in Gestational Diabetes Mellitus Predicting the Needs for Insulin Therapy by Ya Zhang, Jiashen Shao, Feifei Li, Xianming Xu

“…A total of 1352 patients with GDM diagnosed by the 75-g/2-h oral glucose tolerance test (OGTT) were enrolled in this study. …”
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Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson’s Disease? The Potential Role of Zolpidem in the Treatment of Parkinso... by Antonio Daniele, Francesco Panza, Antonio Greco, Giancarlo Logroscino, Davide Seripa

“…Randomized clinical trials are needed in order to assess the efficacy, safety, and tolerability of zolpidem in treating motor symptoms of PD.…”
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Genome-wide transcriptomics revealed carbon source-mediated gamma-aminobutyric acid (GABA) production in a probiotic, Lactiplantibacillus pentosus 9D3 by Nachon Raethong, Pitakthai Chamtim, Roypim Thananusak, Kanyawee Whanmek, Chalat Santivarangkna

“…The integration of transcriptome data with a genome-scale metabolic network (GSMN) revealed that L. pentosus 9D3 displays adaptability by synthesizing GABA as an alternative acid-tolerant mechanism when lactose is used as a carbon source rather than depending on the fatty acid synthesis and the arginine catabolic pathway. …”
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A Component-Based Parametric Reduced-Order Modeling Method Combined with Substructural Matrix Interpolation and Automatic Sampling by Ying Liu, Hongguang Li, Yun Li, Huanyu Du

“…The exact error of the assembled model at the optimal parameter point is subsequently calculated to determine whether the automatic sampling procedure reaches a desired error tolerance. The proposed framework is then applied to the moving coil of electrical-dynamic shaker to illustrate the advantage and validity. …”
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Fault Diagnosis of Piezoelectric Sensor Patches for Vibration Control Based on Multifeature Fusion and Improved SVM by Tian-bing Ma, Zhou Qing, Du Fei, Liu Jian

“…The fault diagnosis of piezoelectric sensor patches is very important for the stability of the vibration control system and fault-tolerant control technology. In order to improve the accuracy of fault self-diagnosis of piezoelectric sensor patches, singular value decomposition (SVD) and Hilbert marginal spectrum method are proposed to extract multiple features of each IMF component and conduct feature fusion, and a support vector machine (SVM) based on particle swarm optimization (PSO) is designed for fault identification of different eigenvalues. …”
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Copolymer SJ-1 as a Fluid Loss Additive for Drilling Fluid with High Content of Salt and Calcium by Hongping Quan, Huan Li, Zhiyu Huang, Tailiang Zhang, Shanshan Dai

“…Good temperature resistance and salt tolerance of “–SO3-” of AMPS, strong absorption ability of “amino-group” of AM, and good hydrability of side chain polyoxyethylene ether (C2H4O)n of APEG provide SJ-1 excellent properties as a fluid loss additive. …”
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Janus kinase inhibitors in rheumatoid arthritis-associated interstitial lung disease: where do we stand and what may be the future? by Beatrice Maranini, Roberta Foti, Moustapha Taha, Veronica Venturelli, Andrea Lo Monaco, Marcello Govoni

“…In some cohorts, JAKis determined even an encouraging improvement in lung disease, and few reports presented good tolerability of JAKis in combination with antifibrotics. …”
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Origin of the MRI Contrast in Natural and Hydrogel Formulation of Pineapple Juice by Domenico Rizzo, Enrico Ravera, Marco Fragai, Giacomo Parigi, Claudio Luchinat

“…Natural oral contrast agents, such as fruit juice, have the advantages of better taste, tolerability, and lower price with respect to the artificial agents. …”
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A meta-analytic evaluation of the efficacy and safety of levetiracetam for treating myoclonic seizures by Sara Najafi, Mohaddeseh Sadat Alavi, Hamid Reza Sadeghnia

“…Furthermore, it is well-tolerated and responsible for a few side-effects. However, it is necessary to monitor carefully LEV's individual response.…”
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ANGPTL4 induces Kupffer cell M2 polarization to mitigate acute rejection in liver transplantation by Weifeng Huang, Liqing Jiang, Yingsong Jiang, Shanshan Li, Wanqi Liu, Kezhen Zong, Dadi Peng, Zhongjun Wu, Zuotian Huang

“…Using a rat orthotopic liver transplantation model, we observed reduced ANGPTL4 expression during AR, whereas increased ANGPTL4 levels were linked to immune tolerance. Administration of ANGPTL4 recombinant protein improved liver function, suppressed inflammation, and promoted M2 polarization of KCs. …”
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The IVIG treatment response in autoimmune polyendocrine syndromes type 2 with anti-GAD65 antibody-associated stiff person syndrome: a case report and literature review by Yulong Yang, Hailin Jiang, Wenming Yang, Wenming Yang, Wenming Yang, Han Wang, Han Wang, Meixia Wang, Meixia Wang, Xiang Li, Peng Huang, Shuzhen Fang, Wenjie Hao, Yue Yang, Furong Zhao, Wei He

“…Autoimmune polyendocrine syndromes (APS) is a rare group of disorders caused by impaired function of multiple endocrine glands due to disruption of immune tolerance. Of which, type 2 (APS-2) is the most common. …”
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Transcriptomic Analysis Reveals Molecular Mechanisms Underpinning Mycovirus-Mediated Hypervirulence in <i>Beauveria bassiana</i> Infecting <i>Tenebrio molitor</i> by Charalampos Filippou, Robert H. A. Coutts, Ioly Kotta-Loizou, Sam El-Kamand, Alexie Papanicolaou

“…Genes that participate in carbohydrate assimilation and transportation, and those essential for fungal survival and oxidative stress tolerance, calcium uptake, and iron uptake, were found to be overexpressed in the virus-infected isolate during the mid-infection stage. …”
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Investigation of Digital Light Processing-Based 3D Printing for Optimized Tooling in Automotive and Electronics Sheet Metal Forming by Szabolcs Szalai, Brigitta Fruzsina Szívós, Vivien Nemes, György Szabó, Dmytro Kurhan, Mykola Sysyn, Szabolcs Fischer

“…Measurements using digital image correlation (DIC) revealed minimal wear and deformation, with tolerances consistently within IT 0.1 mm. The results demonstrated that SLA-printed tools perform comparably to conventional metal tools in cutting and bending operations, achieving similar surface quality and edge precision while significantly reducing the production time and cost. …”
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Retention and Clinical Performance of Zirconia Crowns: A Comprehensive Review by Fatemeh Soleimani, Hamid Jalali, Azam Sadat Mostafavi, Somayeh Zeighami, Maryam Memarian

“…Overall, although clinical long-term and follow-up studies are a vital requirement to conclude that zirconia has great reliability, it seems that zirconia crown restorations are both well tolerated and sufficiently resistant.…”
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