CD4+ T Cells Mediate Dendritic Cell Licensing to Promote Multi‐Antigen Anti‐Leukemic Immune Response by Luis Gil‐de‐Gómez, Joseph J. Mattei, Jessica H. Lee, Stephan A. Grupp, Gregor S. D. Reid, Alix E. Seif

“…Results In our model, leukemia responsiveness correlates with in vivo CD4+ T cell activation and DC maturation, supporting a role for DC licensing. In contrast, tolerance is characterized by in vivo increased expression of negative immune checkpoints (IC) which may suppress rather than license DC. …”
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Accidental intra-arterial injection of enoxaparin sodium leading to abdominal wall expanding subcutaneous hematoma and abdominal wound: case report-vascular by Caroline Howell, Richard Simman, Richard Simman, Richard Simman

“…It is generally well-tolerated and has a favorable safety profile. The most common injection site reactions caused by enoxaparin sodium are urticaria, ecchymosis, and skin and fat necrosis.Case ReportA 56 year-old female with extensive thromboembolic history was completing an enoxaparin sodium bridge to warfarin when she accidentally self-injected enoxaparin sodium into the left superficial epigastric artery, resulting in the formation of a large expanding hematoma and the development of hemorrhagic shock. …”
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Trained Innate Immunity by Repeated Low-Dose Lipopolysaccharide Injections Displays Long-Term Neuroprotective Effects by Xiao-yan Zhou, Rong Gao, Jian Hu, Da-peng Gao, Yan-ling Liao, Jian-jun Yang

“…In the present study, mice received daily intraperitoneal injection of low-dose lipopolysaccharide (LPS, 0.1 mg/kg) for three consecutive days to induce immune memory (immune tolerance) and then were subjected to sham operation or cecal ligation and puncture (CLP) 9 months later, followed by a battery of neurobehavioral and biochemical studies. …”
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L-Arginine Supplementation in Type II Diabetic Rats Preserves Renal Function and Improves Insulin Sensitivity by Altering the Nitric Oxide Pathway by Taylor Claybaugh, Sarah Decker, Kelly McCall, Yuriy Slyvka, Jerrod Steimle, Aaron Wood, Megan Schaefer, Jean Thuma, Sharon Inman

“…Marked improvements in glucose tolerance were also observed in the LA treated diabetic rats. …”
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Independent Benefits of Meeting the 2008 Physical Activity Guidelines to Insulin Resistance in Obese Latino Children by Nazrat Mirza, Matilde Palmer, Johanna O'Connell, Loretta DiPietro

“…Clinical assessments of body composition, resting energy expenditure (REE), as well as glucose and insulin responses to an oral glucose tolerance test (OGTT) were performed after an overnight fast. …”
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A very low carbohydrate diet improved metabolic profile in congenital generalized lipodystrophy type 4 by Sayantan Chakraborty, Subhankar Roy, Debaditya Das, Sayantani Chatterjee, Pranab Kumar Sahana, Satinath Mukhopadhyay

“…The serum levels of glucose and triglyceride did not reduce significantly, even with maximally tolerated doses of metformin (2 g), pioglitazone (45 mg) and fenofibrate (160 mg), not uncommonly seen in poor rural families in West Bengal, India. …”
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RESPONSE OF WHEAT TO DIFFERENT ABIOTIC STRESS CONDITIONS: A REVIEW by Harikala Paudel, Radhakrishna Bhandari, Anjali Dhakal, Shivalal Nyaupane, Binod Panthi, Mukti Ram Poudel

“…The study of wheat against such circumstances would help plant breeders identify stress-tolerant genotypes that could significantly contribute to eradicating existing hunger and malnutrition in the world.…”
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The shifting of buffer crop repertoires in pre-industrial north-eastern Europe by Meiirzhan Abdrakhmanov, Michael Kempf, Ruta Karaliute, Piotr Guzowski, Rimvydas Lauzikas, Margaux L. C. Depaermentier, Radosław Poniat, Giedre Motuzaite Matuzeviciute

“…Our findings revealed that rye remained a main staple crop throughout the studied periods reflecting environmental adaptation to northern latitudes. The drought-tolerant and thermophilic millet crop exhibited resilience during the adverse dry climatic conditions of the Medieval Climatic Anomaly while showing a significant decline during the Little Ice Age. …”
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Highly bright perovskite light-emitting diodes enabled by retarded Auger recombination by Zhiqi Li, Qi Wei, Yu Wang, Cong Tao, Yatao Zou, Xiaowang Liu, Ziwei Li, Zhongbin Wu, Mingjie Li, Wenbin Guo, Gang Li, Weidong Xu, Feng Gao

“…Trifluoroacetate anions can additionally alter the crystallization dynamics and inhibit halide migration, facilitating charge injection balance and improving the tolerance of perovskites under high voltages. Our findings shed light on a promising future for perovskite emitters in high-power light-emitting applications, including laser diodes.…”
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A Case of Uterine Lymphangioleiomyomatosis Complicated by Tuberous Sclerosis Complex by Kaori Yamada, Yukio Yamanishi, Junichi Aratake, Nanayo Sasagasako, Yoshihide Inayama, Rei Gou, Atsuko Kawamura, Megumi Yamanishi, Kenzo Kosaka

“…Subsequently, laparoscopic hysterectomy and bilateral salpingectomy were performed since she could not tolerate everolimus for a long period due to the medication’s side effects. …”
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Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice by Yang Long, Dan Jia, Libin Wei, Yumei Yang, Haoming Tian, Tao Chen

“…Increased GGT activity had no effect on the glucose tolerance but could facilitate blood glucose lowering after intraperitoneal insulin administration. …”
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A Case of Ruptured Aortic Arch Aneurysm Successfully Treated by Thoracic Endovascular Aneurysm Repair with Chimney Graft by Yohei Kawatani, Yujiro Hayashi, Yujiro Ito, Hirotsugu Kurobe, Yoshitsugu Nakamura, Yuji Suda, Takaki Hori

“…TEVAR using the chimney graft technique could be an effective treatment option for patients with a decreased ability to tolerate surgery.…”
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Genetic Diversity and Population Structure of Tomato (<i>Solanum lycopersicum</i>) from the USDA-GRIN Germplasm Collection by Ibtisam Alatawi, Haizheng Xiong, Hanan Alkabkabi, Kenani Chiwina, Qun Luo, Kai-Shu Ling, Yuejun Qu, Renjie Du, Ainong Shi

“…These findings provide essential insights into the genetic diversity and population structure of tomato, offering valuable information for breeding programs aimed at improving traits such as yield, stress tolerance, and disease resistance. The results further underscore the role of global germplasm exchange in shaping the genetic landscape of tomato accessions.…”
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Clinical application of hempseed or flaxseed oil-based lyotropic liquid crystals: Evaluation of their impact on skin barrier function by Vitek Mercedes, Matjaž Mirjam Gosenca

“…The short- and long-term effects of LCCs on TEWL, SC hydration, erythema index, melanin index, and tolerability were determined and compared with baseline. …”
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A large giant cell tumor of the larynx: case report and review of the literature by Andrew Arndt, Rachelle LeBlanc, Peter Spafford

“…Currently the patient has no evidence of disease at 13 months follow-up, has an optimal prosthetic voice, and is able to tolerate all textures of foods. Conclusion GCTs of the larynx have a good prognosis and can be treated successfully through complete resection of the tumor, negating the need for adjunctive therapy such as radiation, chemo or denosumab therapy.…”
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Konsep Entrepreneur Dalam Dunia Pendidikan by Alzet Rama, Ganefri Ganefri, Asmar Yulastri

“…Unsur-unsur entrepreneurship merupakan The entrepreneur,Inovation,Organization creation,Creating value,Profit dan non profit, Growth, Uniqueness.Process. karakteristik entrepreneurship yaitu Risk taking, Innovatives, Locus of Control, Need for Achievement, Self Efficacy Tolerance of Ambiguity. Entrepreneurship pendidikan ada beberapa metode yaitu Termasuk mata kuliah kewirausahaan, Mencantumkan jiwa entrepreneurship dalam setiap mata pelajaran, Mengurutkan dan memilih informasi (teori) yang paling relevan dengan tujuan masing-masing mata pelajaran sambil, sejauh mungkin, memberikan bobot pada penerapannya sesuai dengan penerapan contoh nyata di daerah setempat. …”
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Relationship of individual psychological factors of cadets’ adaptation in voyage conditions by O. Ivanova, Y. Chumaieva, S. Kushchinska

“…Based on these factors, an empirical study was organised, which revealed the relationship between indicators of psychological stability, self-confidence, adaptability, and tolerance to ambiguity. It was determined that psychological resilience is associated with the parameters of passion, resourcefulness, optimism, and the level of expression of motivational components of professional activity of cadets, determined by the motives of life support and self-realisation. …”
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Immune Privilege and Eye-Derived T-Regulatory Cells by Hiroshi Keino, Shintaro Horie, Sunao Sugita

“…The eye and immune system use strategies to maintain the ocular immune privilege by regulating the innate and adaptive immune response, which includes immunological ignorance, peripheral tolerance to eye-derived antigens, and intraocular immunosuppressive microenvironment. …”
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Open-label use of Anakinra (Kineret) in the treatment of patients with osteoarthritis by Craig Davis Scoville, John Partridge Dickson

“…Background: Novel treatments for osteoarthritis (OA) are needed for patients not responding to and/or not tolerating conventional treatments. In this prospective study the usefulness of Anakinra (Kineret) in the treatment of OA was evaluated. …”
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Influence of Bio-fertilization on Physical and Biochemical Parameters of Grapefruit Saplings Citrus paradisi Macfad. Under Salt Stress by Sabaa J. Abdulkadhim

“…This experiment aimed to know the role of biofertilization in increasing the ability of grapefruit seedlings to tolerate salt stress. Biofertilizers were applied with four levels (without biofertilizers, mycorrhizal fungi, bacteria, and mycorrhizae + bacteria). 20 g of mycorrhizal fungi were added near the saplings roots. 20 ml of bacteria were injected into the soil and in contact with the root zone. …”
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