Preparation and Evaluation of Intravaginal Ring Containing Drospirenone by Ying Zhang, Chun-Xiao Li, Mei-Ying Ning, Xue-Yan Duan, Ying Liu

“…Biocompatibility of reservoir system was evaluated by tolerability on tissue level in rats. It was found that, under strong light exposure, high temperature, and high humidity conditions, drospirenone and excipients had no significant interactions. …”
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Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis by Francesca Leonardis, Viviana De Angelis, Francesca Frisardi, Chiara Pietrafitta, Ivano Riva, Tino Martino Valetti, Valentina Broletti, Gianmariano Marchesi, Lorenza Menato, Roberto Nani, Franco Marson, Mirca Fabbris, Luca Cabrini, Sergio Colombo, Alberto Zangrillo, Carlo Coniglio, Giovanni Gordini, Lucia Stalteri, Giovanni Giuliani, Vittorio Dalmastri, Gaetano La Manna

“…Therapy proved to be safe and well tolerated. From this first experience, extracorporeal cytokine removal seems to be a valid and safe therapy in the management of meningococcal and pneumococcal diseases and may contribute to the patient stabilization and prevention of severe sequelae. …”
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Mitigating biomass recalcitrance for plant‐based bioenergy production by Vincent Ninkuu, Zhixin Liu, Yaping Zhou, Enzhi Guo, Xiao Song, Peibo Gao, Yajia Xie, Xuwu Sun

“…Abstract The emission of greenhouse gases, particularly carbon dioxide, predominantly from fossil fuel combustion has received critical warnings several times as their levels exceed the tolerable limits in view of global warming. This calls for a paradigm shift from a fossil fuel‐based source to a less hazardous bioenergy source. …”
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Reusable and robust fuzzy extractor for CRS-dependent sources by Yucheng Ma, Peisong Shen, Xue Tian, Kewei Lv, Chi Chen

“…These instantiations result in the first reusable and robust fuzzy extractor for CRS-dependent sources that can tolerate linear errors.…”
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β-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia by Kristoffer L. Egerod, Chunyu Jin, Pia Steen Petersen, Nils Wierup, Frank Sundler, Birgitte Holst, Thue W. Schwartz

“…Although the overexpression of the constitutively active GPR39 receptor in animals not treated with streptozotocin appeared by itself to impair the glucose tolerance slightly and to decrease the β-cell mass, it nevertheless totally protected against the gradual hyperglycemia in the steptozotocin-treated animals. …”
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Human T follicular helper cells and their impact on IgE and IgG4 production across allergy, malignancy, and IgG4-related disease by Mitsuhiro Akiyama, Waleed Alshehri, Sho Ishigaki, Koichi Saito, Yuko Kaneko

“…Their critical role in diseases such as allergy, malignancy, and IgG4-related disease highlights their profound impact on balancing inflammation and immune tolerance. Our current review provides the molecular characteristics of human Tfh cells, the differentiation pathways of Tfh subsets, mechanisms by which Tfh subsets induce IgE and IgG4 production, and their clinical implications in allergy, malignancy, and IgG4-related disease.…”
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Recent Insights into Antibiotic Resistance in Helicobacter pylori Eradication by Wenming Wu, Yunsheng Yang, Gang Sun

“…Since the worldwide increase in the rate of antibiotic resistance represents a problem of relevance, some studies have been performed in order to identify highly active and well-tolerated anti-H. pylori therapies including sequential, concomitant quadruple, hybrid, and quadruple therapy. …”
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Performance analysis of dual stator six‐phase embedded‐pole permanent magnet synchronous motor for electric vehicle application by Raja Ram Kumar, Priyanka Devi, Chandan Chetri, Ankita Kumari, Papu Moni Saikia, Ram Khelawan Saket, Kundan Kumar, Baseem Khan

“…Moreover, the availability of two sets of the stator winding enhances the performance efficiency and ensures the proposed motor's more significant fault‐tolerating ability of the motor. For performance evaluation, the Finite Element Method analysis is chosen, as it gives appropriate and precise results. …”
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Growth and Survival of Acid-Resistant and Non-Acid-Resistant Shiga-Toxin-Producing Escherichia coli Strains during the Manufacture and Ripening of Camembert Cheese by M. P. Montet, E. Jamet, S. Ganet, M. Dizin, S. Miszczycha, L. Dunière, D. Thevenot, C. Vernozy-Rozand

“…AR and NAR STEC were able to survive during the manufacture and ripening of Camembert cheese prepared from microfiltered milk with no evidence of induced acid tolerance in NAR STEC strains.…”
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Magnetic-Guided Capsule Endoscopy in the Diagnosis of Gastrointestinal Diseases in Minors by Yuting Qian, Tingting Bai, Juanjuan Li, Yi Zang, Tong Li, Mingping Xie, Qi Wang, Lifu Wang, Ruizhe Shen

“…MGCE is a safe, effective, and well-tolerated procedure with good sensitivity and has a potential clinic value for the diagnosis of gastrointestinal diseases in minors.…”
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Phosphorus and Nutrition in Chronic Kidney Disease by Emilio González-Parra, Carolina Gracia-Iguacel, Jesús Egido, Alberto Ortiz

“…But the interaction between intestinal dysbacteriosis in dialysis patients, phosphate binder efficacy, and patient tolerance to the binder could reduce their efficiency.…”
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Improved Stem Cell MR Detectability in Animal Models by Modification of the Inhalation Gas by Uwe Himmelreich, Ralph Weber, Pedro Ramos-Cabrer, Susanne Wegener, Korinna Kandal, Eric M. Shapiro, Alan P. Koretsky, Mathias Hoehn

“…This change in protocol of physiological conditions was well tolerated by all studied animals, even over prolonged experimental times. …”
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Optimization of circular coils with ferrite boxes for enhanced efficiency in wireless power transfer for electric vehicles by Soukaina Jaafari, Hamza El Hafdaoui, Khadija Ajabboune, Ahmed Khallaayoun, Esmail Ahouzi

“…Equivalent coils with ferrite boxes meet a 95% efficiency goal with a strong, narrowed field at a lower cost, while inequivalent coils excel in strengthening and centralizing the field, enhancing misalignment tolerance in distinctive ways.…”
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Alkyl polyglucoside vs. ethoxylated surfactant-based microemulsions as vehicles for two poorly water-soluble drugs: physicochemical characterization and in vivo skin performance by Pajić Nataša Z. Bubić, Todosijević Marija N., Vuleta Gordana M., Cekić Nebojša D., Dobričić Vladimir D., Vučen Sonja R., Čalija Bojan R., Lukić Milica Ž., Ilić Tanja M., Savić Snežana D.

“…In addition, results of the in vivo skin performance study supported acceptable tolerability for all investigated formulations, suggesting selected microemulsions as promising carriers worth exploring further for effective skin delivery of model drugs.…”
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Case Report of Presumed (In)voluntary Capsaicin Intoxication Mimicking an Acute Abdomen by Simona Koprdova, Christine Schürmann, Dirk Peetz, Thomas Dürbye, Frank Kolligs, Herbert Koop

“…A 27-year-old man took part in a qualifying for a competition in spicy food tolerance. During this qualifying, he swallowed 4 chili peppers type Bhut jolokia (about 1 million Scoville units) and other extremely spicy foods; the total amount of capsaicin ingested (roughly calculated retrospectively) accounted for at least 600 mg. …”
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Influence of Zeolite, Kaolin, and Chitosan on the Growth and Productivity of Strawberry by Walid F. A. Mosa, Khalid Almutairi, Krzysztof Górnik, Lidia Sas-Paszt

“…Therefore, the application of plant biostimulants and biostimulant-like substances has become necessary to improve the availability and absorption of nutrients, enhance growth, yield, quality, and tolerance to abiotic and biotic stresses, and serve as an alternative to mineral fertilizers. …”
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Influence of Low-Temperature Stress-Relieving Treatment in the Fatigue Life of Components Produced by Laser Powder Bed Fusion in AlSi10Mg by Malcolm António, Rui Fernandes, Joel de Jesus, Luís Borrego, Ricardo Branco, José da Costa, José Ferreira

“…The findings suggest that low-temperature stress-relieving treatment can enhance the fatigue performance of L-PBF AlSi10Mg components by reducing residual stresses and improving defect tolerance.…”
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Investment and Saving Among House Hold in Kabale District: A Case Study of Kitumba Sub-County Kabale District. by Aturinde, Annitor

“…Factors influencing saving and investment decisions included financial literacy, religious beliefs, income levels, age, risk tolerance, employment type, family size, rationality in decision-making, and education levels. …”
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Inhalation d'aérosols liquides ou solides chez les Primates Non Humains by Jérôme Montharu, Chrystophe Aubert, Georges Roseau, Laurent Vecellio, Antoine Guillon, Michèle de Monte

“…Afin de tester l'efficacité de drogues, d'évaluer leur cinétique, leur tolérance pulmonaire et/ou leur toxicité, nous avons donc développé des modèles précliniques incluant les rongeurs, les porcs, et les primates non humains (PNH). …”
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Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19: A multicenter, randomized, double-blind, phase 1b trial by Norberto Chavez-Tapia, Muneeba Ahsan Sayeed, Shobha Luxmi, Douglas J. Kasper, Fenchao Xue, Yang Shen, Weiliang Fan, Wei Yuan, Bin Du

“…The primary objective was to evaluate SIR1-365 safety and tolerability. Secondary objectives included an assessment of SIR1-365 efficacy. …”
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