First-in-human, multicenter, open-label, phase I study of ATOR-1017 (evunzekibart), a 4-1BB antibody, in patients with advanced solid malignancies by Peter Ellmark, Jeffrey Yachnin, Ana Carneiro, Lena Schultz, Amanda Hahn, Sumeet Ambarkhane, Karin Enell Smith, Gustav J. Ullenhag

“…The primary objective of the study included determination of the maximum tolerated dose (MTD) via assessment of adverse events and dose-limiting toxicities (DLTs). …”
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Epicutaneous immunotherapy for food allergy: a systematic review and meta-analysis by Xiaohong Xiang, Jingwei Hu, Rangui Sachu, Chonghua Gao, Hongyan Niu, Yi Gao, Shiju Chen, Xiaotian Cui, Xiang Li

“…Conclusion After EPIT treatment, patients with food allergy can effectively increase their immune tolerance to food. However, it also significantly increases mild-to-moderate anaphylaxis. …”
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In vivo scanning laser fundus and high-resolution OCT imaging of retinal ganglion cell injury in a non-human primate model with an activatable fluorescent-labeled TAT peptide probe... by Xudong Qiu, Seth T Gammon, Carol Rasmussen, Federica Pisaneschi, Charlene B Y Kim, James Ver Hoeve, Steven W Millward, Edward M Barnett, T Michael Nork, Paul L Kaufman, David Piwnica-Worms

“…In normal healthy eyes, intravitreal injection of 3 nmol of TcapQ488 was well-tolerated, while 12 nmol of TcapQ488 to the healthy eye caused extensive probe activation in the ganglion cell layer (GCL) and eventual retinal nerve fiber layer thinning. …”
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Factors influencing the natural history of non-IgE-mediated gastrointestinal food allergies in paediatric age: a prospective multicentre cohort study by Giorgio Bedogni, Roberto Berni Canani, Laura Carucci, Rita Nocerino, Serena Coppola, Pasqualina Capasso, Veronica Giglio

“…At 24-month follow-up, 54% of patients acquired immune tolerance. This rate was higher in FPIAP (75%), when compared with FPIMD (62%), FPE (54%) and FPIES (24%). …”
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Repetitive Transcranial Magnetic Stimulation for the Treatment of Complex Regional Pain Syndrome: A Pilot Study by Foglia SD, Drapeau CC, Ramdeo KR, Adams FC, Soppitt DB, Rehsi RS, Shanthanna H, Nelson AJ

“…Clinical outcomes included pain intensity using the numerical ratings scale, Pain Catastrophizing scale-EN-SF, PROMIS-29 v2.0 profile, and Rainbow Pain Scale.Results: All participants tolerated the study procedures and 83% of participants completed the 9-week intervention, deeming the protocol feasible. …”
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Efficacy and Prognostic Factors for Y-90 Radioembolization (Y-90) in Metastatic Neuroendocrine Tumors with Liver Metastases by Erica S. Tsang, Jonathan M. Loree, Janine M. Davies, Sharlene Gill, David Liu, Stephen Ho, Daniel J. Renouf, Howard J. Lim, Hagen F. Kennecke

“…In our population-based cohort, Y-90 was well-tolerated in patients with metastatic liver-dominant NETs. …”
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Residue depletion profile and withdrawal interval estimation of ivermectin in eggs following topical administration of injectable ivermectin to domestic chickens (Gallus domesticus... by Melissa A. Mercer, Jennifer L. Davis, Scott E. Wetzlich, Maaike O. Clapham, Lisa A. Tell

“…The results provide insight into how the estimated ivermectin egg WDIs using regulatory methods differ based on the maximum residue limit/tolerance applied and portion of the terminal elimination phase sampled.…”
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BRAF inhibitor monotherapy in BRAFV600E-mutated pediatric low-grade glioma: a single center’s experience by S. S. McThenia, S. S. McThenia, S. S. McThenia, K. M. Reddy, K. M. Reddy, E. Damaraju, E. Castellino, Z. He, R. Beer, F. Chien, F. Chien, F. Chien, R. C. Castellino, R. C. Castellino, R. C. Castellino, A. E. Goldman-Yassen, A. E. Goldman-Yassen, J. R. Fangusaro, J. R. Fangusaro, J. R. Fangusaro, T. MacDonald, T. MacDonald, T. MacDonald

“…Objective Response (OR) for 15 evaluable patients on BRAF inhibitor (BRAFi) therapy: 73% (0/15 CR + 6/15 PR + 5/15 MR) with Overall Response Rate (ORR=CR+PR): 40%. Overall, patients tolerated treatment well with Grade 1 rash being the most common toxicity. …”
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The Combination of Gastroschisis, Jejunal Atresia, and Colonic Atresia in a Newborn by Zachary Bauman, Victor Nanagas

“…Our case report also demonstrates primary enteric anastomosis as a safe, well-tolerated surgical option for patients with types of intestinal atresia.…”
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IEEE 802.11 WLAN analytical model for M2M small data service by WANG Ya-hui, CHI Xue-fen

“…Machine to machine（M2M） communications had a huge potential market.Wireless local area network（WLAN） as the main complement for 3G networks would carry a lot of M2M services.Considering the characteristics of typical M2M small data service which was delay tolerant and retry patient,a large time-scale backoff algorithm was proposed in the network model of IEEE 802.11 DCF.MAC layer service time probability distribution was derived,and IPP/G/1/K discrete-time queuing model was established in order to analyze the QoS performance of M2M under unsaturated traffic condition and imperfect channel in the WLAN.Simulation results indicate that the proposed algorithm effectively enhances system throughput and reduces system blocking rate.…”
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Les nouveaux intellectuels religieux saoudiens : le Wahhabisme en question by Stéphane Lacroix

“…We will finally examine the limits of this critique: while the regime can, if it suits its temporary interests, tolerate, and even encourage, a degree of religious criticism, it cannot let this criticism turn into what many of these intellectuals consider as its natural corollary, i.e. political criticism.…”
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Efficient and provably-secure certificateless sequential aggregate signature scheme by Zhu WANG, Siqi YANG, Fenghua LI, Kui GENG, Tingting PENG, Mengyao SHI

“…Aiming at the problem that current schemes mostly let the latter signer to verify the multiple signatures of the previous signer, and the message is signed and then passed to the next signer, leading to the efficiency problem of long overall signature time.A sequential aggregate signature scheme based on bilinear pairs was proposed.The aggregate signatures of documents were generated by multiple users in a certain order, and only the final signature was needed to be verified to confirm the correct order of signatures and the legitimacy of multiple user signatures.The complexity of verifying the multi-user sequential signature was effectively reduced and the offline verification of the authenticity of signature was realized when the user was offline or in a delay-tolerant network with limited node caching capacity and network resources.It is shown that the proposed scheme is existential unforgeability against chosen-message attacks under adversary adaptive selection messages in the random oracle model.…”
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Polynomial estimation method for PN sequence based on reliability accumulation by Song CHEN, Kai-zhi HUANG, Hua ZHAO

“…The issues of insufficient efficiency and poor error-tolerance of current high-order polynomial estimation me-thods under error conditions were studied.By combining the iterative berlekamp-massey(BM)algorithm in GF(2)and the improved Chase algorithm,a novel algorithm based on reliability accumulation was proposed.The sequence soft infor-mation was mapped to sequence reliability as the input information of BM algorithm,and the corresponding output relia-bility of estimated polynomial was accumulated as the rule of correct polynomial.In order to improve the estimation pre-cision,the candidate reliability-accumulated polynomial set were reduced by the characteristics of primitive polynomial in GF(2).The simulation results show that the proposed method is irrelevant with the tapped number of ator poly-nomial,and has a good estimation performance to estimate 17-order polynomials when the sequence BER is 18%.…”
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Murder and Aesthetics in Patricia Highsmith’s Deep Water by Robert Lance Snyder

“…An esteemed non-conformist in an upscale New England community, Van Allen is initially tolerant of his wife’s serial infidelities but reaches a breaking point when he kills two of her lovers before strangling his spouse. …”
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Image thresholding based on two-dimensional histogram oblique segmentation and its fast recurring algorithm by WU Yi-quan, PAN Zhe, WU Wen-yi

“…It makes the inner part uniform,the edge accurate in the thresholded image and has better tolerance capability to noise. At the same time the running time is significantly reduced.…”
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Goji Berry: a Novel Nutraceutical "Superfruit" for Florida Master Gardeners by Yujie Jiao, Guodong Liu

“…Most of Florida’s climate is favorable for goji berry, and a few Florida growers have cultivated it for years. This species can tolerate infertile and unfavorable growth conditions, and the prominent health benefits of this crop may be highly profitable for Florida growers. …”
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Study on the Finite Element Simulation Method of the Belt Skew by Huang Zhuo, Han Fenglin, Yan Hongzhi, Li Peng

“…The belt skew caused by manufacturing and assembly tolerance frequently occurs in engineering practice. …”
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Kitsch, classes sociales et multiculturalisme dans My Beautiful Laundrette (Stephen Frears, 1985) by Lionel Souquet

“…Combining socio-cultural, ethnic and feminist issues to the question of homosexuality, Frears and Kureishi question the capacity of a society in crisis to accept or simply tolerate all forms of differences. Innovative in a positive and militant representation of homosexuality, My Beautiful Laundrette is emblematic of the renaissance of the British film industry of the 1980s. …”
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Croton Production and Use by Robert H. Stamps, Lance S. Osborne

“…Since some cultivars are tolerant of interior environments, crotons have also become very popular as interior potted foliage plants. …”
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Recent advancements to enhance the therapeutic efficacy of antiepileptic drugs by Li Fuquan, Singh Akhilesh Vikram

“…Antiepileptic drugs must be used only if the ratio of efficacy, safety, and tolerability of treatment are favorable and outweigh the disadvantages including treatment costs. …”
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