CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production by Emily E. O’Driscoll, Sakshi Arora, Jonathan F. Lang, Beverly L. Davidson, Ophir Shalem

“…Recombinant adeno-associated virus (rAAV) vectors are an effective and well-established tool in the growing gene therapy field, with five U.S. Food and Drug Administration-approved AAV-mediated gene therapies already on the market and numerous more in clinical trials. …”
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Model for predicting metabolic activity in athletes based on biochemical blood test analysis by Victoria A. Zaborova, Evgenii I. Balakin, Ksenia A. Yurku, Olga E. Aprishko, Vasiliy I. Pustovoyt

“…The use of the developed model will also allow us to assess the nature of adaptation to specific muscular work, identify an athlete's weaknesses, forecast the success of their performance, and timely adjust both the training process and the recovery program.…”
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Powdery mildew resistance of apple clonal rootstocks from the collection of the Michurinsk State Agrarian University by I. N. Shamshin, M. L. Dubrovsky, A. A. Trifonova, K. V. Boris, A. M. Kudryavtsev

“…The results of a three-year field evaluation of powdery mildew resistance of 80 rootstocks allowed us to distinguish five main groups ranging from very low to highly resistant. …”
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Evaluation of the impact of PEPFAR transition on retention in care in South Africa’s Western Cape Province by J Chiliza, R Laing, F G Feeley, A T Brennan

“…Research on the impact of the US President’s Emergency Plan for AIDS Relief (PEPFAR) transition in South Africa (SA) in 2012 found varying results in retention in care (RIC) of people living with HIV (PLWH). …”
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Morphological and molecular characterization of a Sarcocystis bovifelis-like sarcocyst in American beef by Aditya Gupta, Larissa S. de Araujo, Andrew Hemphill, Asis Khan, Benjamin M. Rosenthal, Jitender P. Dubey

“…Although S. hominis has been reported as prevalent in Europe, the occurrence of thick-walled species in the US remains poorly known. Here, for the first time to our knowldge, we characterize a thick-walled Sarcocystis species from a sample of beef from a local grocery store in Maryland. …”
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Co-effects of COVID-19 and Meteorology on PM2.5 Decrease in Ho Chi Minh City, Vietnam: A Comparison of 2016–2019 and 2020–2021 by Cong-Thanh Tran, Le My Thuan Nguyen, Tzong-Gang Wu, Chang-Fu Wu, To Thi Hien, Kuo-Liong Chien

“…In conclusion, the large decrease of PM2.5 concentrations during the unprecedented period of COVID-19 pandemic gave us a better chance to more fully comprehend the PM2.5 pollution status in HCMC for future reference.…”
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Association between metabolic score for visceral fat index and BMI-adjusted skeletal muscle mass index in American adults by Yifan Zhou, Xiangjie Su, Haitao Tan, Jun Xiao

“…Methods We conducted a cross-sectional study using data from the NHANES database, focusing on U.S. adults aged 20 years and older from 2013 to 2018. …”
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IoT based intelligent pest management system for precision agriculture by Salman Ahmed, Safdar Nawaz Khan Marwat, Ghassen Ben Brahim, Waseem Ullah Khan, Shahid Khan, Ala Al-Fuqaha, Slawomir Koziel

“…Abstract Despite seemingly inexorable imminent risks of food insecurity that hang over the world, especially in developing countries like Pakistan where traditional agricultural methods are being followed, there still are opportunities created by technology that can help us steer clear of food crisis threats in upcoming years. …”
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Design and development of a low-cost, eco-friendly forklift for sustainable logistics management by Asif Jalal, Muhammad Farooq, Izza Anwer, Nasir Hayat, Adeel Munir, Imran Zahid, Noreen Sher Akbar, M. Hamza, M. Nouman, Fahid Riaz

“…The U.S. Occupational Safety and Health Administration’s (OSHA) most recent estimates show that between 35,000 and 62,000 injuries occur every year due to forklift-related accidents. …”
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Management Modalities of Mandible Fracture and Dental Trauma in Pediatric Patients During Mixed Dentition Phase: A Series of Case Study by Lomtu Ronrang, Alice Lyngdoh

“…All these uncertain factors, including the natural way of protection bestowed on us by nature during the childhood stage, might be the actual factors that can easily resist any form of minor trauma in pediatric patients. …”
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Stroke Induces a BDNF-Dependent Improvement in Cognitive Flexibility in Aged Mice by Josh Houlton, Lisa Y. Y. Zhou, Deanna Barwick, Emma K. Gowing, Andrew N. Clarkson

“…Recently, we have established an animal model of stroke that results in delayed impairment in spatial memory, allowing us to better investigate cognitive deficits. Young and aged brains show different recovery profiles after stroke; therefore, we assessed aged-related differences in poststroke cognition. …”
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Novel protein-based prognostic signature linked to immunotherapeutic efficiency in ovarian cancer by Shuo-Fu Chen, Liang-Yun Wang, Yi-Sian Lin, Cho-Yi Chen

“…The algorithm began by clustering patients using immune-related gene sets, which allowed us to identify immune-related proteins of interest. …”
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The impact of the international rice genebank’s (IRG) on rice farming in Bangladesh by Donald Villanueva, Yuji Enriquez, Grace Lee Capilit

“…This yield increase can be translated into an additional US$ 8,576,973 aggregated net benefit of farmers during the wet season in Bangladesh. …”
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Evaluation of the immunological functions of placental alkaline phosphatase in vivo using ALPP transgenic mice by Tse-Ching Chen, Kwai-Fong Ng, Ning Chen, Yi-Ling Pan, Chun-An Cheng, Hsiao-Chun Wu, Yi-Jen Hsueh, Nien-Yi Chiang, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin, Hsi-Hsien Lin

“…Placental alkaline phosphatase (ALPP) is one of tissue-specific ALP isozymes expressed mostly during pregnancy, however it was found to be differentially upregulated in certain hepatocellular carcinomas by us recently. In addition, ALPP has been identified as a reliable biomarker of diverse germ cell tumors. …”
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Permafrost Dynamics Observatory: 3. Remote Sensing Big Data for the Active Layer, Soil Moisture, and Greening and Browning by Elizabeth Wig, Kevin Schaefer, Roger Michaelides, Richard Chen, Leah K. Clayton, Brittany Fager, Lingcao Huang, Andrew D. Parsekian, Howard Zebker, Yingtong Zhang, Yuhuan Zhao

“…Remote sensing enables us to study permafrost at high resolution and over large areas. …”
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A short ncRNA modulates gene expression and affects stress response and parasite differentiation in Leishmania braziliensis by José C. Quilles, Caroline R. Espada, Lissur A. Orsine, Tânia A. Defina, Letícia Almeida, Fabíola Holetz, Angela K. Cruz

“…Studies of the mechanisms regulating gene expression in Leishmania led us to investigate noncoding RNAs (ncRNAs) as regulatory elements. …”
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Protecting the American dream for socially vulnerable families: An evaluation of state-level policies to improve housing security and protect mobile home communities by Morgan Clennin, Denise Hartsock, Olivia Goodman, Stacie Daugherty, Cheryl Kelly

“…Background: Manufactured and mobile homes are the largest source of unsubsidized affordable housing in the U.S. However, mobile home residents face unique challenges and are at greater risk of housing instability. …”
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Assessing knowledge management and time performance of building construction projects in Ghana by Francis Gyimah, Kheni Nongiba Alkanam, Elijah Kusi, Fredrick Simpeh

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Don’t move a mussel: The role of key environmental drivers and management scale in assessing spatial variation in dreissenid spread risk in the Missouri River basin by Joseph Raymond, Lucas S. Bair, Timothy D. Counihan, Wesley M. Daniel, Sofie Duntugan, Matthew E. Neilson, Michael Springborn

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Outcomes of Age-Friendly Health Systems: Return to Clinic After 4Ms Care Delivery by Grace Q. Armstrong MPH, Heba M. Aldossary MSN, RN, Jessica Bingham BSN, Lilia Pino PhD, RN, FNP-C, Anne Pohnert DNP, RN, FNP-BC, Mary A. Dolansky PhD, RN, FAAN, Nicholas K. Schiltz PhD

“…A retrospective cohort design using electronic health record (EHR) data obtained from patients 65 years of age and older who received care at a large national network of convenient care clinics in the U.S. ( N  = 987,197) between January 2021 and March 2024. …”
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