Huntington’s disease modeling on HEK293 cell line by D. V. Sharipova, T. B. Malankhanova, A. A. Malakhova

“…The new genome editing approaches, such as CRISPR/Cas9, allow us to generate isogenic cell lines that can be useful for drug screening and studying mechanisms of molecular and cellular events triggered by certain mutation on an equal genetic background. …”
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Effects of Low-Load Blood Flow Restriction Training on Rotator Cuff Strength and Hypertrophy: Case Series by Daniel W Safford, Kshamata M Shah, Frederic Breidenbach, Philip W McClure

“…The dependent variables were maximal isometric strength of the shoulder external rotators(ER) and elevators (in the scapular plane in full can position) (FC) measured via handheld dynamometry, cross sectional area (CSA) of the supraspinatus and infraspinatus muscles, and supraspinatus tendon thickness measured via ultrasound imaging (US). Mean changes within and between arms were compared after training using paired t-tests. …”
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Utilizing ATLS® Trauma Management Protocols: The Gold Standard for Safe and Effective Care. by Agron Dogjani, Edvin Selmani, Edmond Zaimi, Kastriot Haxhirexha, Petrit Biberaj, Basri Lenjani, Kastriot Subashi, Ilir Hasmuca, Erjona Zogaj, Amarildo Blloshmi, Klevis Doci

“…Traumatic injury is the leading cause of death under the age of 45 in the U.S. and worldwide. Traumatic injuries represent a significant global health burden, demanding swift and decisive intervention to mitigate morbidity and mortality. …”
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Germany-Iran Relations in Political-Military Sphere: The Impossible Unlocking of Potential? by V. S. Мirzekhanov, Ph. O. Trunov

“…The authors try to estimate the probable position of Germany towards possible military-political crisis in the region involving Iran and especially towards a potential US war against Iran.What result will Germany strive for in the Iranian direction? …”
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LIVER DISEASE & SICKLE CELL DISEASE: AUTOIMMUNE HEPATITIS MORE THAN A COINCIDENCE; A SYSTEMATIC LITERATURE REVIEW. by Kelvin Lynch, Andrea Mega, Andrea Piccin, Massimo Daves, Helen Fogarty

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The effect of physical activity on markers of oxidative and antioxidant stress in cancer patients: a systematic review and meta-analysis by Laerte Jônatas Leray Guedes, Victória Brioso Tavares, Saul Rassy Carneiro, Laura Maria Tomazi Neves

“…Six databases were used for the search (EMBASE, The Cochrane Library (CENTRAL), US National Library of Medicine (PubMed), Physiotherapy Evidence Database (PEDro), Cumulative Index of Nursing and Allied Health (CINAHL) and SPORTDiscus via EBSCO) until January 31st, 2024. …”
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Field apple scab susceptibility of a diverse Malus germplasm collection identifies potential sources of resistance for apple breeding by David Papp, Liqiang Gao, Ranjita Thapa, Dan Olmstead, Awais Khan

“…We also screened a differential host set for 2 years to monitor for changes in the effectiveness of ten known scab resistance genes, which allowed us to confirm the presence of virulent pathogen races in the orchard. …”
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Enhancing Disaster Situation Awareness Through Multimodal Social Media Data: Evidence from Typhoon Haikui by Songfeng Gao, Tengfei Yang, Yuning Xu, Naixia Mou, Xiaodong Wang, Hao Huang

“…Additionally, the Geodetector was used to investigate spatial heterogeneity and its underlying factors. This approach allowed us to analyze the spatiotemporal patterns of disaster evolution, enabling rapid disaster damage assessment and facilitating emergency response efforts. …”
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Associations between dietary fatty acids and kidney stones by Ning Tan, Ya Zhang

“…This study investigates the association between dietary fatty acid intake—specifically saturated (SFA), monounsaturated (MUFA), and polyunsaturated fatty acids (PUFA)—and the prevalence of kidney stones in a U.S. adult population, aiming to inform potential dietary prevention strategies. …”
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Hospital Surgical Volume, Utilization, Costs and Outcomes of Retroperitoneal Lymph Node Dissection for Testis Cancer by Hua-yin Yu, Nathanael D. Hevelone, Sunil Patel, Stuart R. Lipsitz, Jim C. Hu

“…Methods and Materials. Using the US Nationwide Inpatient Sample from 2001–2008, we identified 993 RPLND and used propensity score methods to assess utilization, costs, and inpatient outcomes based on hospital surgical volume. …”
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Heart Rate Variability in Children with Tricyclic Antidepressant Intoxication by Ener Cagri Dinleyici, Zubeyir Kilic, Sabiha Sahin, Rabia Tutuncu-Toker, Makbule Eren, Zeynel Abidin Yargic, Pelin Kosger, Birsen Ucar

“…These findings provided us with a starting point for the value of HRV analysis in determining the risk of arrhythmia and convulsion in TCA poisoning patients. …”
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Effect of Toll-Like Receptor 4 on Synovial Injury of Temporomandibular Joint in Rats Caused by Occlusal Interference by Jingjing Kong, Yingying Yang, Shuzhen Sun, Jianli Xie, Xuefen Lin, Ping Ji

“…In addition, the inflammation reactions and the increased expression of IL-1β could be restrained by treatment with TAK-242, a blocker of TLR4 signaling. The results prompted us that the activation of TLR4 may be involved in the inflammatory reactions and increased expression of IL-1β in patients with synovitis and participate in the mechanisms of the initiation and development of synovial injury by regulating the expression of inflammatory mediators like IL-1β in synovial membranes.…”
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The subcompartmented oxphosomic model of the phosphorylating system organization in mitochondria by I. V. Ukolova

“…These data have allowed us to reconsider the contemporary concept of the phosphorylation system organization and propose a new subcompartmented oxphosomic model. …”
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Fracture Modeling of Deep Tight Sandstone Fault-Fracture Reservoir Based on Geological Model and Seismic Attributes: A Case Study on Xu 2 Member in Western Sichuan Depression, Sich... by Jitong Li, Junlong Liu, Hongde Chen, Jianhua He, Ruyue Wang, Xupeng Shao, Xin Fang

“…Based on available data sources, including core samples, well logs, and outcrop data, we utilized a combination of geophysical and geological modeling techniques to clarify the characteristics of effective fractures in tight gas reservoirs. This allowed us to construct a geological model of a tight sandstone fault-fracture gas reservoir in the Xu 2 Member of the Xujiahe Formation located in the Xinchang area, which represents a fault-fracture reservoir formed by high-angle faulting-derived fractures and controlled by the S-N trending fault. …”
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Improving Distributed Decision Making in Inventory Management: A Combined ABC-AHP Approach Supported by Teamwork by Ileana Gloria Pérez Vergara, Julián Andrés Arias Sánchez, Rocío Poveda-Bautista, Jose-Antonio Diego-Mas

“…Therefore, the methodology allows us to solve inventory management DDM based on multicriteria ABC classification and was validated in a Colombian company belonging to the graphic arts sector.…”
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Genomic evidence of improved fertility and adaptation in Iranian domestic sheep attributed to introgression from Asiatic Mouflon and urial by Reza Khalkhali-Evrigh, Nemat Hedayat, Reza Seyedsharifi, Mirdarioush Shakouri, Eric N. Ponnampalam

“…This information can enhance our understanding of the impact of wild species on domesticated livestocks, providing us with clearer insights for management, breeding, and conservation of these species.…”
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Strengthening mycology research through coordinated access to microbial culture collection strains by D. Smith, A. Kermode, G. Cafà, A. G. Buddie, T. S. Caine, M. J. Ryan

“…Current technologies enable us to access this latter, hidden resource, thereby facilitating a better understanding of how to harness and manipulate microbial communities to improve crop yields and allow successful interventions such as biocontrol of pests, diseases and invasive species. …”
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Slowly Progressive and Painless Thoracic Aortic Dissection Presenting with a Persistent Fever in an Elderly Patient: The Usefulness of Combined Measurement of Biochemical Parameter... by Shunsuke Yamada, Masanori Tokumoto, Toshiaki Ohkuma, Yasuo Kansui, Yoshinobu Wakisaka, Yuji Uchizono, Kazuhiko Tsuruya, Takanari Kitazono, Hiroaki Ooboshi

“…In the present case, a negative procalcitonin test, increased D-dimer and serum creatinine phosphokinase-BB levels, and reelevation of the CPR level led us to the correct diagnosis.…”
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Imperfect bipolarity: The ‘third power’ factor in Soviet-American relations in the nuclear field (1958–1968) by V. А. Veselov

“…30 years after the end of the Cold War, bipolar structure still dominates in the nuclear sphere, although certain nuclear powers are closing the gap with Russia and the United States in terms of strategic arsenals and the system of world politics in general is moving towards polycentrism. At the same time, as US-Russian relations continue to deteriorate against the backdrop of the ‘Ukrainian crisis’, the prospects for strategic dialogue after the expiration of the Treaty on Measures for the Further Reduction and Limitation of Strategic Offensive Arms (New START) are becoming increasingly vague. …”
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Demographic clinical trial diversity assessment methods: Use of real-world data by Hua Chen, Nnadozie Emechebe, Sudeep Karve, Leon Raskin, Jailene Leal, Ning Cheng, Wendy Sebby, Kim Ribeiro, Samuel Crawford

“…In the United States, clinical trial diversity is often benchmarked against US Census data, which may limit the representativeness of patient demographics in clinical trials. …”
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