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Results of a modified Delphi consensus on the optimal testing pathway for oesophago-gastric cancer care in the UK
Published 2025-02-01“…Given the level of agreement and that the stopping criteria were met, it was decided not to undertake further Delphi rounds.Conclusion The recommendations support the use of a reflex testing approach for human epidermal growth factor receptor 2, programmed death ligand 1 and microsatellite instability high/mismatch repair deficiency in patients diagnosed with OG cancer who are suitable for treatment with targeted therapy.…”
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622
Community engagement initiatives in primary health care to achieve universal health coverage: A realist synthesis of scoping review.
Published 2023-01-01“…., skills and capacity) that are put in place to enable both communities and service providers to undertake successful CE. Process aspects of CE initiatives discussed in the literature included: i) the role of the community in defining priorities and setting objectives for CE, ii) types and dynamics of the broad range of engagement approaches and activities, and iii) presence of an on-going communication and two-way information sharing. …”
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623
Revisiting Weimar Film Reviewers’ Sentiments: Integrating Lexicon-Based Sentiment Analysis with Large Language Models
Published 2024-07-01“…In a two-step process, we first harness ChatGPT's more nuanced grasp of language to undertake a verbose sentiment analysis, in which the model is prompted to explain its judgment of the film reviews at length. …”
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624
Improving drug–target affinity prediction by adaptive self-supervised learning
Published 2025-01-01“…Through this two-stage feature extraction design, each stage undertakes specific tasks, fully leveraging the advantages of each model while efficiently integrating information from different data sources, providing a more accurate and comprehensive solution for drug-target affinity prediction. …”
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625
Co-Optimization Operation of Distribution Network-Containing Shared Energy Storage Multi-Microgrids Based on Multi-Body Game
Published 2025-01-01“…In the first stage, a multi-objective optimization configuration model for shared energy storage among multi-microgrids is established, with optimization objectives balancing the randomness of renewable energy fluctuations and the economics of each microgrid undertaking shared energy storage. The charging and discharging interactive power of energy storage and each microgrid at various time periods are obtained and passed to the second stage. …”
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626
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627
Oral manifestations of Nance Horan syndrome: A systematic review of case reports
Published 2024-09-01“…However, due to the sporadicity of cases and the similarity in manifestations of mild NHS with X-linked cataracts, it is difficult for clinicians and researchers to diagnose and treat NHS. Therefore, we undertake a comprehensive review of the existing literature on the oral manifestations of NHS and, its definitive diagnosis based on oral and craniofacial symptoms. …”
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628
Efficacy and safety of Mahuang Fuzi and Shenzhuo Decoction for treatment of primary membranous nephropathy: a multicenter prospective trial
Published 2024-12-01“…Background This study aims to undertake a comprehensive assessment of the effectiveness and safety profile of Mahuang Fuzi and Shenzhuo Decoction (MFSD) in the management of primary membranous nephropathy (PMN), within the context of a prospective clinical investigation.Methods A multicenter, open-label clinical trial was executed on patients diagnosed with PMN. …”
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629
Long-term planning optimisation of sustainable energy systems: A systematic review and meta-analysis of trends, drivers, barriers, and prospects
Published 2025-01-01“…In this context, the paper undertakes a systematic and comprehensive review, synthesising existing empirical evidence concerning the long-term procurement of renewable energy resources with differing optimisation objectives and within the framework of diverse constraints. …”
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630
How does community health feature in Global Financing Facility planning documents to support reproductive, maternal, newborn, child and adolescent health and nutrition (RMNAH-N)? i...
Published 2024-12-01“…Results In country documents, there is a commitment to community health, with significant attention paid to various cadres of community health workers (CHWs) who undertake a range of preventive, promotive and curative roles across RMNCAH-N spectrum. …”
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631
Core Outcome Set development for LEPtospirosis trials (COS-LEP): a study protocol to develop a core outcome set for the evaluation of clinical therapeutic interventions for human l...
Published 2025-01-01“…This includes (1) a systematic review of available quantitative and qualitative literature reporting therapeutic response and safety outcomes and measures; (2) focused interviews with healthcare professional and people treated for leptospirosis exploring outcomes of interests using qualitative methodology; (3) narrowing the choice of outcomes by international consensus using a Delphi survey process; and (4) undertaking a hybrid consensus meeting with key stakeholders to build the final COS. …”
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632
Building a practice-based research network for healthcare integration: a protocol paper for a mixed-method project
Published 2022-06-01“…The overall project aim is to build a sustainable collaboration between a PBRN and an Advanced Health Research and Translation Centre to generate a research platform suitable for planning, undertaking and translating research to improve care across the healthcare continuum.Methods and analysis We will use a developmental evaluation design. …”
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633
The assessment of change in human heat stress risk in Brazil projected by the CMIP6 models
Published 2025-01-01“…If the temperature rise exceeds 3 °C, then almost the entire country at some point in the year will have levels of WBGT that would pose a high risk to health for people undertaking physical activity. Furthermore, 8% of the population will be affected for almost half of the year. …”
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634
Investigation of Kidney Histopathology in Rats Receiving Methamphetamine Simultaneously with Berberine Hydrochloride and Aerobic Exercise
Published 2025-01-01“…Introduction: Given the widespread issue of methamphetamine addiction and its damaging effects, coupled with the crucial role of the kidneys in maintaining bodily equilibrium, we chose to undertake this study. Methods: Forty rats were randomly divided into five equal groups: control, methamphetamine, methamphetamine with exercise, methamphetamine with berberine hydrochloride, and methamphetamine with both exercise and berberine hydrochloride. …”
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635
Adipocyte heterogeneity and tumor infiltration of adipose tissue in patients with metastatic breast cancer
Published 2025-02-01“…The microscopic tumor cell infiltration observed in the visceral fat, mainly for ILC, underscores the need to undertake additional research to understanding the contribution of the adipose tissue in breast cancer metastasis.…”
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636
Phytochemical screening and neuro-pharmacological activity of Mimosa pudica flowers: Integrating in vitro, in silico and in vivo approaches
Published 2025-02-01“…The objective of our research is to examine the various pharmacological uses of this mysterious plant by undertaking a thorough investigation of its methanolic extract. …”
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637
Prospective evaluation of the impact of repeated whole prison testing for hepatitis C
Published 2025-02-01“…Therefore, resources should be focused on optimising reception testing rather than undertaking repeated HITTs.…”
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638
Experimental Estimation of the Heat Transfer Coefficient of an Unglazed Solar Plate for Unsteady Humid Outdoor Condition
Published 2021-01-01“…This research presents a study on the heat transfer coefficient for an unglazed solar plate collector in an unsteady humid outdoor environment. The purpose for undertaking this research is to investigate the correlation between the heat transfer coefficient and air speed and also verify whether heat transfer from unglazed solar thermal collectors under outdoor conditions can be experimentally determined using a particular mathematical relationship for different locations. …”
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639
Tracing the Intellectual History of the Knowledge Economy: An Analysis of OECD Publications within the International Political Economy Framework
Published 2021-11-01“…From its inception, the OECD has evolved into an intellectual hub, generating influential documents that exert a substantial impact on the national economic policies of a diverse array of countries, irrespective of their membership status within the organization. This study undertakes an assessment of the evolution of the “knowledge economy” concept within the OECD, employing a dual analytical framework that encompasses intellectual history and international political economy (IPE), with a predominant focus on the neo-Gramscian school of thought within the IPE paradigm.Our recourse to the neo-Gramscian branch of IPE serves the purpose of delineating the role played by the “knowledge economy” within the broader context of power dynamics and the competing interests of influential groups capable of wielding political and economic influence. …”
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640
What can qualitative research do for randomised controlled trials? A systematic mapping review
Published 2013-06-01“…Researchers can increase the impact of this work on trials by undertaking more of it at the pretrial stage and being explicit within their articles about the learning for trials and evidence-based practice.…”
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