A novel frameshift variant of GATA3 (p.Ala17ProfsTer178) responsible for HDR syndrome in a Japanese family by Yutaka Hasegawa, Toshie Segawa, Ai Chida, Eriko Yoshida, Hirofumi Kinno, Hiraku Chiba, Tomoyasu Oda, Yoshihiko Takahashi, Koji Nata, Yasushi Ishigaki

“…Genetic testing revealed a novel GATA3 gene variant at exon 2 (c.48delC), which induces a frameshift resulting in termination at codon 178, causing HDR syndrome. We summarized 45 Japanese cases of HDR syndrome with regard to the mode of onset (familial or sporadic) and the age at diagnosis. …”
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Leptin Enhances Synthesis of Proinflammatory Mediators in Human Osteoarthritic Cartilage—Mediator Role of NO in Leptin-Induced PGE2, IL-6, and IL-8 Production by Katriina Vuolteenaho, Anna Koskinen, Meiju Kukkonen, Riina Nieminen, Unto Päivärinta, Teemu Moilanen, Eeva Moilanen

“…The results suggest that the effects of leptin are mediated through activation of transcription factor nuclear factor κB (NF-κB) and mitogen-activated protein kinase (MAPK) pathway c-Jun NH2-terminal kinase (JNK). Interestingly, inhibition of leptin-induced NO production with a selective iNOS inhibitor 1400 W inhibited also the production of IL-6, IL-8, and PGE2, and this was reversed by exogenously added NO-donor SNAP, suggesting that the effects of leptin on IL-6, IL-8, and PGE2 production are dependent on NO. …”
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N-Methyl-D-Aspartate Receptors Involvement in the Gentamicin-Induced Hearing Loss and Pathological Changes of Ribbon Synapse in the Mouse Cochlear Inner Hair Cells by Juan Hong, Yan Chen, Yanping Zhang, Jieying Li, Liujie Ren, Lin Yang, Lusen Shi, Ao Li, Tianyu Zhang, Huawei Li, Peidong Dai

“…In normal mature mouse cochleae, the majority of NMDARs were distributed on the modiolar side of IHCs and close to the IHC nuclei region, while most of synaptic ribbons and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) were located on neural terminals closer to the IHC basal poles. After gentamicin exposure, the NMDARs increased and moved towards the IHC basal poles. …”
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Engineering triple O-Ti-O vacancy associates for efficient water-activation catalysis by Feng Bi, Qingjie Meng, Yili Zhang, Hao Chen, Boqiong Jiang, Hanfeng Lu, Qinghua Liu, Hongjun Zhang, Zhongbiao Wu, Xiaole Weng

“…Experimental and theoretical analyses demonstrate that terminal hydroxyls adsorbed at unsaturated cationic sites play an essential role in boosting VOVTiVO formation, which enhances H2O dissociation and facilitates dissociative OH* deprotonation for defect site regeneration. …”
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The geometry evolution of Early Paleozoic carbonate platform in the southwestern Tarim Basin, China: evidence from sequence stratigraphic analysis and seismic forward modeling by Jie Li, Jie Li, Zicheng Cao, Feng Geng, Suju Yang, Xuguang Sha, Mingjie Lan, Shenghou Wang, Yongchao Lu, Yangbo Lu, Daqing Tang, Zhao Zhang, Fang Hao

“…Inside of the high-amplitude interval, the seismic reflection terminated at the top reflector. Seismic forward modeling was performed to examine the validity of possible hypothetical models in the studied area. …”
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Gallstone Ileus following Endoscopic Stone Extraction by Yoshiya Yamauchi, Noritaka Wakui, Yasutsugu Asai, Nobuhiro Dan, Yuki Takeda, Nobuo Ueki, Takahumi Otsuka, Nobuyuki Oba, Shuta Nisinakagawa, Tatsuya Kojima

“…The next day, the patient developed abdominal pain, abdominal distension, and nausea and was diagnosed as having gallstone ileus based on abdominal computed tomography (CT) and abdominal ultrasonography findings of an incarcerated stone in the terminal ileum. Although colonoscopy was performed after inserting an ileus tube, no stone was visible. …”
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Folded pseudochiral Fermi surface in 4Hb-TaSe2 from band hybridization with a charge density wave by Matthew D. Watson, Andrea Tonelli, Mugerabe Zerabza, Sam Hayward, Rebecca Wilkinson, Ettore Carpene, Cephise Cacho, Valentina De Renzi, Simon Crampin, Enrico Da Como

“…Using selective area angle resolved photoemission spectroscopy on the T termination combined with ab initio calculations, we unveil a finely structured Fermi surface arising from band folding in the reconstructed Brillouin zone caused by the CDW star clusters. …”
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Creation of a nationwide breastfeeding policy for surgical residents: a scoping review protocol by Natalia Ziolkowski, Larissa Rogowsky, Julia Innis, Angela Grant Buechner, Elena Springall, Jana Dengler

“…After returning from maternity leave, surgical trainees face extensive barriers to breast feeding and tend to terminate breast feeding earlier than guideline recommendations. …”
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Low-Bit Rate Feedback Strategies for Iterative IA-Precoded MIMO-OFDM-Based Systems by Sara Teodoro, Adão Silva, Rui Dinis, Atílio Gameiro

“…We design low-complexity and low-bit rate feedback strategies where a quantized version of some CSI parameters is fed back from the user terminal (UT) to the base station (BS), which shares it with the other BSs through a limited-capacity backhaul network. …”
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Optimal power dispatch method for wind farms considering service quality and available power by Xueting Cheng, Juan Wei, Hanzhi Peng, Jinhao Wang, Fan Hu, Liming Bo

“…Active power allocation is constrained by the power demand instructions, while reactive power allocation aims to maintain the WT terminal voltage within a feasible range. The proposed method can ensure the fair power allocation within WFs to meet the requirements of equipment reliability, voltage safety, and power supply simultaneously, which can improve resource utilization and avoid the potential failure. …”
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Placenta Percreta at 17 Weeks with Consecutive Hysterectomy: A Case Report and Review of the Literature by Natasha Gupta, Anu Gupta, Marlene Green, Hyung Shik Kang, Josef Blankstein

“…We reviewed all reported cases of first and second trimester placenta percreta in the literature, to emphasize the early recognition of abnormal placentations in patients with risk factors, consider prenatal evaluation in such patients, anticipate complicated placental implantations during termination procedures, and prevent associated maternal morbidity and mortality.…”
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Report of a Novel Mutation in MLH1 Gene in a Hispanic Family from Puerto Rico Fulfilling Classic Amsterdam Criteria for Lynch Syndrome by Juan M. Marqués-Lespier, Yaritza Diaz-Algorri, Maria Gonzalez-Pons, Marcia Cruz-Correa

“…This deletion causes a frameshift in the protein coding sequence at p.682 resulting in premature termination and a truncated MLH1 protein. To our knowledge, this mutation has not been previously reported in the literature. …”
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Enhancement of Anti-Inflammatory and Osteogenic Abilities of Mesenchymal Stem Cells via Cell-to-Cell Adhesion to Periodontal Ligament-Derived Fibroblasts by Keita Suzuki, Naoyuki Chosa, Shunsuke Sawada, Naoki Takizawa, Takashi Yaegashi, Akira Ishisaki

“…The subsequent adherence of MSCs to PDL-Fs plays an immunomodulatory role to terminate inflammation during wound healing and upregulates the expression stem cell markers to enhance the stemness of MSCs, thereby facilitating bone formation in damaged PDL tissue.…”
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A single-cell 3D dynamic volume control system for chondrocytes by Qiang Zhang, Yiyao Wang, Yanjun Zhang, Xiaochun Wei, Weiyi Chen, Quanyou Zhang

“…Chondrocyte hypertrophic phenotype is a criticle physiological process which indicates a hallmark of chondrocyte terminal differentiation and bone formation. Thus, developing a in vitro cell culture system for dynamic regulation of single chondrocyte volume at a three-dimensional (3D) level is particularly necessary for understanding how physical cues of matrix microenvironment regulate chondrocyte fate and the degeneration of articular cartilage. …”
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Ultrastructure of Placenta of Gravidas with Gestational Diabetes Mellitus by Qian Meng, Li Shao, Xiucui Luo, Yingping Mu, Wen Xu, Chao Gao, Li Gao, Jiayin Liu, Yugui Cui

“…On TEM, the distinct ultrastructural alterations indicating the degeneration of terminal villi were found in the GDM placentas as follows: thickening of the basal membrane (BM) of vasculosyncytial membrane (VSM) and the VSM itself, significantly fewer or even absent syncytiotrophoblastic microvilli, swollen or completely destroyed mitochondria and endoplasmic reticulum, and syncytiotrophoblasts with multiple vacuoles. …”
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Structural characterization and immunostimulatory activity of a water-soluble polysaccharide from abalone (Haliotis discus hannai Ino) muscle by Linfan Shi, Gengxin Hao, Jun Chen, Junling Wang, Wuyin Weng

“…The linkages of AMPP consisted of terminal, 1,4-linked, 1,6-linked, and 1,4,6-linked Glcp with a molar ratio of 3.1:7.2:1.0:2.5. …”
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Modeling and Control Strategy for Multiterminal Flexible DC Distribution Network with Echelon Utilization Power Battery by Min Mou, Yuhao Zhou, Wenguang Zheng, Yurong Xie, Shipeng Wang, Lili Liu, Chengzhi Wei

“…To achieve a DC network connection of various types of power supply and load, this paper proposes a starting method of multiterminal flexible DC distribution network and a cooperative control strategy of the wind-solar-storage system. A six-terminal ring-shape DC distribution network model is built in real-time digital simulation (RTDS) platform. …”
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A Logical Hierarchical Hidden Semi-Markov Model for Team Intention Recognition by Shi-guang Yue, Peng Jiao, Ya-bing Zha, Quan-jun Yin

“…Additionally, the LHHSMM explicitly models the duration of team working mode, the intention termination, and relations between the world state and observation. …”
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Preclinical assessment of splicing modulation therapy for ABCA4 variant c.768G>T in Stargardt disease by Dyah W. Karjosukarso, Femke Bukkems, Lonneke Duijkers, Tomasz Z. Tomkiewicz, Julia Kiefmann, Andrei Sarlea, Sander Bervoets, Irene Vázquez-Domínguez, Laurie L. Molday, Robert S. Molday, Mihai G. Netea, Carel B. Hoyng, Alejandro Garanto, Rob W. J. Collin

“…A recurrent variant at the exon-intron junction of exon 6, c.768G>T, causes a 35-nt elongation of exon 6 that leads to premature termination of protein synthesis. Methods To correct this aberrant splicing, twenty-five 2′-O-methoxyethyl antisense oligonucleotides (AONs) were designed, spanning the entire exon elongation. …”
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Doubly Fed Induction Machine Models for Integration into Grid Management Software for Improved Post Fault Response Calculation Accuracy—A Short Review by Andrija Mitrovic, Luka Strezoski, Kenneth A. Loparo

“…During faults, voltage drops at the stator terminals lead to elevated voltages and currents on the rotor side due to electromagnetic coupling between stator and rotor, potentially damaging rotor insulation and costly power electronics. …”
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