Associations among circulating sphingolipids, β-cell function, and risk of developing type 2 diabetes: A population-based cohort study in China. by Huan Yun, Liang Sun, Qingqing Wu, Geng Zong, Qibin Qi, Huaixing Li, He Zheng, Rong Zeng, Liming Liang, Xu Lin

“…Network analysis further identified 5 modules, and 2 modules containing saturated sphingomyelins showed the strongest associations with increased T2D risk (RRQ4 versus Q1 = 1.59 and 1.43; both Ptrend < 0.001). …”
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Synergistic antimicrobial activity of essential oils mixture of Moringa oleifera, Cinnamomum verum and Nigella sativa against Staphylococcus aureus using L-optimal mixture design by Samah H. Abu-Hussien, Antony R. Nasry, Ziad Samy, Salwa M. El-Sayed, Ashraf Bakry, Naglaa Ebeed, Hesham Elhariry, Thanaa ElNoby

“…Synergistic interactions between oils further boosted efficacy, with moringa-cinnamon and cinnamon-black seed pairings exhibiting the strongest synergies. The developed predictive models for IZD and MIC showed excellent fit, with R2 values of 0.9843 and 0.9958, respectively. …”
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Fournier Gangrene Associated with Sodium-Glucose Cotransporter-2 Inhibitors: A Pharmacovigilance Study with Data from the U.S. FDA Adverse Event Reporting System by Yang Hu, Ziyu Bai, Yan Tang, Rongji Liu, Bin Zhao, Jian Gong, Dan Mei

“…Among all SGLT2 inhibitor therapies, empagliflozin was associated with the highest number of FG reports (232 in total), while empagliflozin plus metformin had the strongest association with FG occurrence with the reporting odds ratio (ROR 54.79, 95% two-sided CI 31.56 to 95.12) and proportional reporting ratio (PRR 53.36, χ2 666.70). …”
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Factors Predicting Ventilator Dependence in Patients with Ventilator-Associated Pneumonia by Chia-Cheng Tseng, Kuo-Tung Huang, Yung-Che Chen, Chin-Chou Wang, Shih-Feng Liu, Mei-Lien Tu, Yu-Hsiu Chung, Wen-Feng Fang, Meng-Chih Lin

“…Preexisting cardiopulmonary function, high APACHE II and SOFA scores, and high oxygenation index were the strongest predictors of ventilator dependence. Initial empiric antibiotic treatment can improve ventilator weaning rates at the time of discharge.…”
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Identification of macrophage polarisation and mitochondria-related biomarkers in diabetic retinopathy by Weifeng Liu, Bin Tong, Jian Xiong, Yanfang Zhu, Hongwei Lu, Haonan Xu, Xi Yang, Feifei Wang, Peng Yu, Yunwei Hu

“…Immune infiltration analysis showed that activated NK cell and Monocyte were notably different between DR cohort and control cohorts, and PTAR1 showed the strongest positive correlations with activated NK cell. …”
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Perbedaan Kadar Endotelin-1 Plasma pada Penderita Preeklampsia dengan Kehamilan Normotensif by Susi Hartati, Rahmatina B Herman, Darwin Amir

“…<br />Kata kunci: preeklampsia, endotelin-1, normotensif<br /><br />Abstract <br /> Endothelin-1 is potent endothelium derived as the strongest vasocontrictor that has 21 amino acids. Damage of endothelial layer activated the increasing of vasoconstriction which is endothelin-1. …”
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Hubungan Lama Aktivitas Membaca dengan Derajat Miopia pada Mahasiswa Pendidikan Dokter FK Unand Angkatan 2010 by Mutia Maulud Fauziah, M. Hidayat, Julizar .

“…Various factors association with myopia such as heredity and environmental factor. The strongest role an environmental is near work such as reading. …”
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Association between blood test indicators and atrial fibrillation in elderly patients aged 65 and above in the Central Jiangsu region: a cross-sectional study by Hao Liang, Shuai Zhang, Ye Zhu

“…The ROC curve analysis indicates that albumin, direct bilirubin, and uric acid all have good association strength with AF in elderly patients, with direct bilirubin showing the strongest association effect (AUC (95% CI) = 0.728 (0.686, 0.769)). …”
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Associations between Life’s Essential 8 and liver function: a cross-sectional study by Qiaoli Liang, Menglong Zou, Ziming Peng

“…WQS regression identified body mass index, blood pressure, blood glucose, and nicotine exposure as the strongest contributors to liver function markers. These findings underscore the potential of LE8 scores as a comprehensive indicator for liver health, particularly in younger populations.ConclusionThis study suggests that LE8 scores is associated with improved liver function. …”
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Chemical Composition and Antioxidant and Antimicrobial Activities of Wormwood (Artemisia absinthium L.) Essential Oils and Phenolics by Kamel Msaada, Nidhal Salem, Olfa Bachrouch, Slim Bousselmi, Sonia Tammar, Abdulkhaleg Alfaify, Khaldoun Al Sane, Wided Ben Ammar, Sana Azeiz, Adel Haj Brahim, Majdi Hammami, Sawsen Selmi, Ferid Limam, Brahim Marzouk

“…Antiradical activity was region-dependant and the methanolic extract of Bou Salem region has the strongest activity (CI50=9.38±0.82 µg/mL). Concerning the reducing power, the methanolic extract of Bou Salem, Jérissa, and Boukornine regions was more active than the positive control. …”
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Lipids and C-reactive protein predict anhedonia and reward circuit functional connectivity responses to anti-cytokine and dopaminergic therapies in patients with depression by Aditya Singh, Mandakh Bekhbat, David R. Goldsmith, Ngoc-Anh Le, Evanthia C. Wommack, Zhihao Li, Ebrahim Haroon, Jennifer C. Felger

“…Responses to infliximab and L-DOPA were strongest in patients with versus without clinically elevated CRP (>3 mg/L) and/or cholesterol (>150 mg/dL)(p < 0.05). …”
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Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Zaid Ahmed Shamsi, Vlad Paraoan, Chang Kim, Sarah Raihanah Saifuddin, Thomas D A Cosker, Duncan Whitwell, Christopher L M H Gibbons, Dionisios Stavroulias, Francesco DiChiara

“…Conclusion Our results indicate that primary resection remains the cornerstone of thoracic sarcoma treatment, representing the single strongest independent factor for survival in treatable cases. …”
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The effects of PM2.5 components on the cardiovascular disease admissions in Shanghai City, China: a multi- region study by Wanying Su, Heping Liu, Tiantian Han, Yunyun Wang, Yi An, Yan Lin

“…$$\:{\text{SO}}_{\text{4}}^{\text{2-}}$$ and BC were strongest associated with CVD admissions in the elderly than in younger people, with increasing interquartile range of the concentrations, the maximum cumulative RR (95% CI) was 1.567 (95% CI: 1.116–2.019) and 1.534 (95% CI: 1.104–1.963), respectively. …”
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Metabolic enzyme inhibitory abilities, in vivo hypoglycemic ability of palmleaf raspberry fruits extracts and identification of hypoglycemic compounds by Jun Tan, Danshu Wang, Yu Lu, Yehan Wang, Zongcai Tu, Tao Yuan, Lu Zhang

“…The 40 % ethanol eluting fraction of 40EUS showed the strongest a-glucosidase inhibition with the IC50 value of 37.79 ng/mL, it could also effectively attenuate the fasting blood glucose level and oral glucose tolerance of C57BL/6 mice. …”
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GAJARDOITE-(NH4), (NH4)As3+ 4O6Cl2[(Ca0.5□0.5)(H2O)5], A NEW MINERAL FROM THE KHOVU-AKSY DEPOSIT, EASTERN SIBERIA, RUSSIA by A.V. Kasatkin, V.V. Gurzhiy, N.V. Chukanov, A.A. Agakhanov, R. Škoda, D.I. Belakovskiy

“…Gajardoite-(NH4) is hexagonal, space group P6/mmm; the unit-cell parameters are as follows: a = 5.263(3), c = 16.078(5) Å, V = 385.8(5) Å3 , Z = 1. The strongest lines of the powder X-ray diffraction pattern [d, Å (I, %) (hkl)] include 16.08 (34) (001), 5.36 (34) (003), 4.565 (41) (100), 3.466 (23) (103), 2.637 (100) (110), 2.360 (25) (113). …”
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Eliciting Preferences for the Uptake of Smoking Cessation Apps: Discrete Choice Experiment by Dorothy Szinay, Rory A Cameron, Andy Jones, Jennifer A Whitty, Tim Chadborn, Jamie Brown, Felix Naughton

“…Relative to other attributes, a 4.8-star user rating, representing social proof, was the strongest driver of app selection (mean preference parameter 2.27, SD 1.55; 95% CI 1.95-2.59). …”
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Blowing Out the Candle: How to Quench Galaxies at High Redshift—An Ensemble of Rapid Starbursts, AGN Feedback, and Environment by Lucas C. Kimmig, Rhea-Silvia Remus, Benjamin Seidel, Lucas M. Valenzuela, Klaus Dolag, Andreas Burkert

“…On longer timescales, >1 Gyr, the environment becomes the strongest predictor, followed by t _50 – t _90 , indicating that at high redshifts the consumption of old gas and lack of new gas are more relevant for long-term prevention of star formation than the presence of a massive AGN. …”
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Stress and Interpersonal Relationships in Medical Students During Public Health Emergencies: A Network Analysis by Cui Y, Guo Z, Yang T, Zhang M, Mu H, Li J, Fang J, Du T, Yang X

“…The edges between S1 “personal hassle” and R3 “dealing with people”, S2 “academic hassle” and R2 “socializing”, and S3 “negative life event” and R4 “dating someone of the opposite sex” were the strongest. S1 “personal hassle” had the greatest BEI of the stress community (0.44), and R3 “dealing with people” had the greatest BEI of the interpersonal relationship community (0.19).Conclusion: This study used network analysis to investigate the relationship between stress and interpersonal relationships in Chinese medical students at the component level for the first time and highlight that the critical bridge variables “personal hassle” and “dealing with people” may contribute to preventing and relieving stress in Chinese medical students.Keywords: medical students, stress, interpersonal relationship, network analysis, public health emergency…”
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Green Extraction of Bioactives from <i>Curcuma longa</i> Using Natural Deep Eutectic Solvents: Unlocking Antioxidative, Antimicrobial, Antidiabetic, and Skin Depigmentation Potenti... by Jelena Jovanović, Marko Jović, Jelena Trifković, Katarina Smiljanić, Uroš Gašić, Maja Krstić Ristivojević, Petar Ristivojević

“…Furthermore, NADES 14 (ChCl/lactic acid/water 1:2:5) demonstrated the strongest tyrosinase inhibition (98.7%), supporting its potential for skin-brightening applications, including notable α-amylase inhibition exceeding 90%. …”
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Chronic kidney disease progression in patients with previous type 2 diabetes and/or hypertension: a population-based cohort study from primary care in Spain by David Vizcaya, Betlem Salvador-González, Oriol Cunillera-Puértolas, Sílvia Cobo-Guerrero, José Romano-Sánchez, Daniel Bundó-Luque, Ariadna Arbiol-Roca

“…Subdistributional hazard ratios (sHRs) were estimated using Cox regression adjusted for confounders.Results Compared with the CKD without hypertension and T2D group, adjusted sHRs (95% CIs) for SKI/kidney failure were 1.77 (1.65 to 1.89) for CKD with hypertension and T2D, 1.50 (1.41 to 1.59) for CKD with hypertension and 1.21 (1.09 to 1.34) for CKD with T2D, and for kidney failure were 1.24 (1.10 to 1.39) for CKD with hypertension, 0.74 (0.61 to 0.90) for CKD with T2D and 1.09 (0.96 to 1.24) for CKD with hypertension and T2D. The strongest risk factors for CKD progression were low eGFR and albuminuria, even at mild-moderate levels.Conclusions Hypertension could be associated with an equal/greater risk of CKD progression as T2D. …”
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