Students’ perspective on new teaching concepts for medical studies: case- and competency-based learning in radiology by Max Masthoff, Friedrich Pawelka, Gisela Zak, Bas de Leng, Dogus Darici, Philipp Schindler, Walter Heindel, Anne Helfen

“…Significant improvement was observed in perceived competency in modality selection and description and interpretation of common pathologies, with the strongest effect for CT and MRI data. The new format was rated more motivating and significantly better in pedagogical and content quality than traditional lectures and seminars, although it did not influence students’ interest in pursuing a radiology career. …”
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Adipocytes from New Zealand Obese Mice Exhibit Aberrant Proinflammatory Reactivity to the Stress Signal Heat Shock Protein 60 by Tina Märker, Jennifer Kriebel, Ulrike Wohlrab, Volker Burkart, Christiane Habich

“…Hsp60 binding involved conserved binding structure(s) and Hsp60 epitopes and was strongest to NZO mouse-derived mature adipocytes. Hsp60 exposure induced KC, IL-6, and MCP-1 release from (pre-)adipocytes of all mouse strains with a pronounced increase of IL-6 release from NZO mouse-derived adipocytes. …”
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Antifungal, toxicological, and colorimetric properties of Origanum vulgare, Moringa oleifera, and Cinnamomum verum essential oils mixture against Egyptian Prince Yusuf Palace deter... by Asmaa Alhussein Mohamed, Mahgoub A. Ahmed, Abdallah S. Korayem, Samah H. Abu-Hussien, Wael Bakry Rashidy

“…Out of the three oils, oregano oil showed the strongest antifungal effect with an inhibition zone diameter (IZD) of 4.5 cm followed by moringa (3.5 cm) and cinnamon (3.2 cm). …”
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Coup (d'etat) in the Baltic States (1926, 1934): Similarities and Differences by Zenonas Butkus

“…Ulmanis was also interested in removing Social Democrats—the strongest political party in Latvia—from their path to power. …”
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How fast is the frequency of precipitation extremes doubling in global land regions? by Guillaume Chagnaud, Juliette Blanchet, Guillaume Evin, Benoit Hingray, Thierry Lebel, Geremy Panthou, Théo Vischel

“…In addition, the rarest events are found to have smaller FDT compared to more ‘common’ extremes; infrastructures designed to withstand the strongest events are thus more exposed to premature obsolescence.…”
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Can the adherence to quality of care indicators for early rheumatoid arthritis in clinical practice reduce risk of hospitalisation? Retrospective cohort study based on the Record L... by Carlo Alberto Scirè, Antonella Zambon, Greta Carrara, Anna Zanetti, Lisa Argnani

“…Among the indicators of the adherence score, early DMARD prescription showed the strongest positive impact, while long-term use of glucocorticoids was the worst negative one.Conclusion In early RA, adherence to quality standards of care is associated with a lower risk of hospitalisation. …”
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Effect of Isoniazid Preventive Therapy on the Incidence of Tuberculosis among Seropositive Children Attending HIV/AIDS Care in Two General Hospitals, Northwest Ethiopia, 2021 by Fassikaw Kebede, Birhanu Kebede, Tsehay Kebede, Melaku Agmasu

“…The human immune deficiency virus (HIV) is the strongest risk factor for the incidence of tuberculosis (TB) by way of reactivation of latent or new infection. …”
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The effect of the APOE4 genotype on physiological and cognitive health in randomised controlled trials with an exercise intervention: a systematic review and meta-analysis by Felicity S. E. Spencer, Richard J. Elsworthy, Leigh Breen, Jon R. B. Bishop, Connor Dunleavy, Sarah Aldred

“…Randomised controlled trials have investigated whether the strongest genetic risk factor for Alzheimer’s disease, APOE4, impacts the effectiveness of exercise on health. …”
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Immune Cells and Intracerebral Hemorrhage: A Causal Investigation Through Mendelian Randomization by Liumei Mo, Wei Pan, Wenjing Cao, Kui Wang, Li'an Huang

“…DP (CD4+CD8+) %T cell (OR = 0.83, CI = 0.72–0.96, p = 0.013) exhibited the strongest protective effect. In contrast, transitional AC (OR = 1.09, CI = 1.02–1.16, p = 0.006) and IgD− CD27− %lymphocyte (OR = 1.08, CI = 1.00–1.17, p = 0.045) showed a higher tendency to increase the ICH risk. …”
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Associations of plasma biomarkers with cerebral perfusion and structure in Alzheimer’s disease by Yong He, Xiaojiao Liu, Fang Liu, Ping Che, Yanxin Zhang, Ruxue Fan, Yuan Li, Wen Qin, Nan Zhang

“…Correlations were found between regional CBF and several plasma biomarkers, with Aβ42 showing the strongest correlation with CBF in the left inferior temporal gyrus (r = 0.507, p = 0.001). …”
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Characterization of visual cognition in pre-manifest, manifest and reduced penetrance Huntington’s disease by Rocio Del Pino, Maria Ángeles Acera, Amaia Ortiz de Echevarrría, Beatriz Tijero, Marta Ruiz-Lopez, Johanne Somme, Javier Ruiz-Martínez, Andrea Gabilondo, Ioana M. Croitoru, Lara Pardina, Naia Ayo-Mentxakatorre, Ane Murueta-Goyena, Iñigo Gabilondo, Rosario Sanchez-Pernaute, Tamara Fernández-Valle, Juan Carlos Gómez Esteban

“…Age, education, CAG repeats, motor status, executive function, and verbal fluency, accounted for up to 72.8% of the variance in general and visual cognitive functions, with motor status having the strongest impact on visual domains in HD carriers. …”
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Magnetic nanoparticles of Nd2Fe14B prepared by ethanol-assisted wet ball milling technique by Younes Mehrifar, Hamed Moqtaderi, Seyedeh Mehri Hamidi, Farideh Golbabaei, Mahdi Hasanzadeh, Somayeh Farhang Dehghan

“…Abstract The magnetic material Nd2Fe14B is one of the strongest magnetic materials found in nature. The demand for the production of these nanoparticles is significantly high due to their exceptional properties. …”
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Impact of a national primary care pay-for-performance scheme on ambulatory care sensitive hospital admissions: a small-area analysis in England by Tim Doran, Christos Grigoroglou, Luke Munford, Evangelos Kontopantelis, Navneet Kapur, Darren Ashcroft, Roger Webb

“…Material deprivation and urbanicity were the strongest predictors of the variation in ACSC rates for all QOF incentivised conditions across England.…”
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Connectome-based disentangling of epilepsy networks from insular stereoelectroencephalographic leads by Kathrin Machetanz, Eliane Weinbrenner, Thomas Volkmar Wuttke, Silke Ethofer, Randolph Helfrich, Josua Kegele, Stephan Lauxmann, Michael Alber, Sabine Rona, Marcos Tatagiba, Holger Lerche, Jürgen Honegger, Georgios Naros

“…Insula-basal ganglia pathways were found in cognitive seizure manifestations, while insular connectivity to fronto-basal regions were strongest in patients with autonomic seizures.ConclusionThe semiology of seizures is mirrored in the functional connectivity of insular epileptic discharges. …”
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Thiosemicarbazone-Based Compounds: A Promising Scaffold for Developing Antibacterial, Antioxidant, and Anticancer Therapeutics by Agnieszka Czylkowska, Monika Pitucha, Anita Raducka, Ewelina Fornal, Edyta Kordialik-Bogacka, Sylwia Ścieszka, Marek Smoluch, Franciszek Burdan, Mateusz Jędrzejec, Paweł Szymański

“…Compound L4 exhibited the strongest inhibitory effect on cancer cell survival. …”
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To use and engage? Identifying distinct user types in interaction with a smartphone-based intervention by Aniek M. Siezenga, Esther C.A. Mertens, Jean-Louis van Gelder

“…Overall, intervention effects were strongest for the user types High engagement–High use and High engagement–Low use. …”
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Association between triglyceride-glucose index and its composite obesity indexes and cardio-renal disease: analysis of the NHANES 2013-2018 cycle by Yu Wu, Chengsen Liu, Jiandong Cao

“…The TYG index was correlated most strongly with CKD (OR 1.42, 95% CI 1.11, 1.82; P = 0.007), while TyG-WHtR had the strongest correlations with CVD (OR 1.63, 95% CI 1.19, 2.22; P = 0.003) and CRS (OR 1.44, 95% CI 1.00, 2.08; P = 0.055). …”
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Factors influencing the unexpected measles outbreak of 2023 in Colombo, Sri Lanka by Kasunee Kalubowila, Chandana Gajanayake

“…Contact history (adjusted OR=8.46) and non/partial vaccination (adjusted OR=6.61) were the strongest predictors of infection. Conclusions & Recommendations: Measles outbreak in 2023 was predominantly driven by unvaccinated individuals and contact with infected cases. …”
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Multi-scale identification of driving forces for landscape ecological risk: A case study of the basin containing three plateau lakes in Yunnan, China by Shu Wang, Quanli Xu, Junhua Yi

“…The LER of the basin was most affected by elevation from 2000 to 2010, with the annual average temperature in 2020 being the strongest driver. The interactions between topography, climate, regional accessibility, and socioeconomic factors exacerbated the degree of LER. …”
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Chemical Constituents and Combined Larvicidal Effects of Selected Essential Oils against Anopheles cracens (Diptera: Culicidae) by Jitrawadee Intirach, Anuluck Junkum, Benjawan Tuetun, Wej Choochote, Udom Chaithong, Atchariya Jitpakdi, Doungrat Riyong, Daruna Champakaew, Benjawan Pitasawat

“…For larvicidal bioassay, all five essential oils exerted promising efficacy in a dose-dependent manner and different performances on A. cracens after 24 hours of exposure. The strongest larvicidal potential was established from P. sarmentosum, followed by F. vulgare, C. longa, M. fragrans, and Z. piperitum, with LC50 values of 16.03, 32.77, 33.61, 40.00, and 63.17 ppm, respectively. …”
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