Progression patterns in patients with advanced hepatocellular carcinoma treated with local therapy, targeted drugs, and PD-1/PD-L1 inhibitors by Yanan Zhao, Di Wu, Quanjun Yao, Hang Yuan, Hongtao Hu, Hailiang Li

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Asymptomatic Intestinal Malrotation Progressing to Midgut Volvulus in a Decompensated Alcoholic Cirrhotic Adult: A Rare Scenario Requiring Special Considerations by Vatche Melkonian, Pablo Quadri, Chintalapati R. Varma, Mustafa Nazzal, Henry B. Randall, Minh-Tri J. P. Nguyen

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Research progress of peer education for stroke patients (同伴教育模式在脑卒中患者中的应用研究进展) by WU Yuanxia (吴远霞), WEI Yan (魏艳)

“…This review summarizes the domestic and foreign research progress on the application of peer education to stroke patients, in order to provide reference for clinical intervention of stroke patients. …”
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An overlap-weighted analysis on the association of constipation symptoms with disease progression and survival in amyotrophic lateral sclerosis: a nested case-control study by Tongyang Niu, Peize Wang, Xiaomeng Zhou, Tingting Liu, Qi Liu, Rui Li, Haitao Yang, Hui Dong, Yaling Liu

“…Patients with ALS constipation exhibited faster disease progression ( p  < 0.001), with a positive correlation between constipation severity and progression rate ( r  = 0.356, p  < 0.001). …”
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CREB3L1 facilitates pancreatic tumor progression and reprograms intratumoral tumor-associated macrophages to shape an immunotherapy-resistance microenvironment by Yu Wang, Haiyan Xu, Li Cai, Yang Sun, Liwei Wang, Ming Yue, Xiaofei Zhang, Yanling Wang, Shumin Li, Shengbai Xue, Jingyu Ma, Tiebo Mao, Weiyu Ge, Daiyuan Shentu, Wenxin Lu, Yongchao Wang, Jiong Hu, Jiujie Cui

“…Functionally, we confirmed CREB3L1 contributing to PDAC malignant progression including growth and metastasis by multiple in in vitro and in vivo models. …”
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A comparative study of legislative and normative frameworks in Morocco, France and U.S.A towards progressive and evolutionary quality management in Moroccan laboratories by Kharrazi Anass, El Ftouh Sobha, El Feniche Mohammed, Bahji Mostafa, Bouaiti El Arbi

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Research progress on climate change adaptation strategies to control invasive crop pest in sub-Saharan Africa: a bibliometric and systematic review by Eméline Sêssi Pélagie Assèdé, Eméline Sêssi Pélagie Assèdé, Calvince Ouko Othoo, Calvince Ouko Othoo, Ahmadou Ly, Gobena Bayisa, Temesgen Gashaw Tarkegn, Temesgen Gashaw Tarkegn, Mègnissè Zohoun, Anje-Jokebed N’goran

“…This bibliometric and systematic review assesses research progress and climate change adaptation strategies to control invasive crop pests in sub-Saharan Africa. …”
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Numbness on the Medical Take: An Atypical Presentation of Guillain‐Barre Syndrome With Unilateral Paraesthesia and Rapid Progression to Bulbar Palsy: A Case Report by J. Stanley, Q. Zhou

“…ABSTRACT Guillain‐Barré syndrome (GBS) is characterized classically by progressive and symmetrical motor weakness and areflexia. …”
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The Prevalence and Progression of Microvascular Complications and the Interaction With Ethnicity and Socioeconomic Status in People With Type 2 Diabetes: A Systematic Review and Meta-Analysis by Thamer Alobaid, Janaka Karalliedde, Matthew DL O’Connell, Luigi Gnudi, Katie Sheehan, Ka Keat Lim, Salma Ayis

“…Conclusion: Ethnicity and SES may be associated with differential risk of development and progression of DN and DR. The available evidence was limited by the number of studies and small samples for certain ethnic/socioeconomic groups.…”
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Machine learning analysis of pathological images to predict 1-year progression-free survival of immunotherapy in patients with small-cell lung cancer by Hirotaka Matsumoto, Hiroaki Akamatsu, Nobuyuki Yamamoto, Yuki Sato, Daichi Fujimoto, Yoshihiko Taniguchi, Motohiro Tamiya, Yasuhiro Koh, Junya Fukuoka, Hisashi Tanaka, Naoki Furuya, Ryota Shibaki, Tsukasa Nozawa, Akira Sano, Yuka Kitamura, Takashi Kijima, Toshihide Yokoyama, Satoru Miura, Akito Hata, Jun Sugisaka

“…We trained a model to predict 1-year progression-free survival (PFS) using pathological images (H&amp;E, programmed cell death-ligand 1 (PD-L1), and double immunohistochemical assay (cluster of differentiation 8 (CD8) and forkhead box P3 (FoxP3)) and patient information. …”
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Research progress of standardization management of nosocomial infection control in the operating room (手术室医院感染规范管理研究进展) by XU Xu (徐旭), REN Guqun (任顾群), SU Yuqiang (苏玉强), WANG Yuena (王岳娜), XU Yuanle (许远乐)

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Upregulation of GSTP1 mediated by chimeric TFE3 promotes TFE3-tRCC progression by targeting JNK signaling pathway by Weixu Chen, Mengtong Wu, Lin Du, Changhua Fang, Hao Wang, Wendi Wang, Chengwei Zhang, Hongqian Guo, Gutian Zhang

“…Furthermore, GSTP1 was found to drive TFE3-tRCC progression via modulation of the JNK signaling pathway. …”
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Association between non-insulin-based insulin resistance indicators and frailty progression: a national cohort study and mendelian randomization analysis by Hui Tian, Yong-meng Li, Cheng-qiang Wang, Guo-qiang Chen, Ying Lian

“…Conclusions The non-insulin-based IR indicators, including TyG index, METS-IR and eGDR, were independently associated with the frailty progression and physical function decline. Monitoring and managing abnormal glucose metabolism should be recommended as a part of comprehensive strategies to prevent or delay the progression of frailty.…”
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma Developed in a Patient with Progressive Muscular Dystrophy: A Case Report and Review of the Literature by Ryo Miyagi, Toshihiko Nishisho, Shinjiro Takata, Yoshimitsu Shimatani, Shunichi Toki, Koichi Sairyo

“…Muscular dystrophy (MD) is characterized by progressive muscle atrophy and its replacement by adipose and fibrous tissue. …”
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LAMB1 downregulation suppresses glioma progression by inhibiting aerobic glycolysis through regulation of the NF-κB/HK2 axis by Zhenxiang Zhao, Haiying Liu, Yingzi Liu, Junpeng Wen, Jiangwei Yuan

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Acute Progressive Visual Loss in a Case of Acute Myeloid Leukemia: Challenges in the Utility of Molecular Tests in Early Diagnose of Cytomegalovirus Retinitis by Ali Amanati, Nader Shakibazad, Bahman Pourabbas, Mohammad Hossein Nowroozzadeh, Soheila Zareifar, Omid Reza Zekavat

“…Herein, we report a 12-year-old boy with acute myeloid leukemia complicated by rapid progressive visual loss during relapse of leukemia. …”
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Activation of FGD5-AS1 Promotes Progression of Cervical Cancer through Regulating BST2 to Inhibit Macrophage M1 Polarization by Guokun Liu, Xuan Du, Li Xiao, Qing Zeng, QianLing Liu

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A handheld milk conductivity sensing device (Mylee) for measuring secretory activation progress in lactating women: a device validation study by Sharon Haramati, Anastasia Firsow, Daniela Abigail Navarro, Ravid Shechter

“…Here we evaluate the validity of a novel milk-sensing device (Mylee) for measuring the progress of milk maturation and secretory activation status. …”
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Outcome of 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy in Progressive Metastatic Neuroendocrine Tumors from a Tertiary Care Center by David Mathew, Saumya S. Sunny, Justin Benjamin, Junita R. John, Felix K. Jebasingh, Josh T. Georgy, Ashish Singh, Regi Oommen

“…The benefit of 177Lu-DOTATATE PRRT in patients with progressive metastatic NET was analyzed and survival in multi-organ involvement. …”
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Bilateral Iliosacral and Transsacral Screws Are Biomechanically Favorable and Reduce the Risk for Fracture Progression in Fragility Fractures of the Pelvis—A Finite Element Analysis by Moritz F. Lodde, Matthias Klimek, Elmar Herbst, Christian Peez, Oliver Riesenbeck, Michael J. Raschke, Steffen Roßlenbroich

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